Effects of angiotensin converting enzyme inhibition on systemic vascular resistance and vasoconstrictor requirements during hypothermic cardiopulmonary bypassC D Deakin
Department of Anaesthetics, Southampton General Hospital, UK
Eur J Cardiothorac Surg 13:546-50. 1998
..We proposed that angiotensin converting enzyme (ACE) inhibitor therapy would alter systemic vascular resistance (SVR) during rewarming and increase the requirement for vasoactive drugs in the immediate post-bypass period...
- Effects of positive end-expiratory pressure on transthoracic impedance--implications for defibrillation
C D Deakin
Department of Anaesthesia, Southampton University Hospitals N H S Trust, Southampton General Hospital, UK
Resuscitation 37:9-12. 1998
..To maximise peak defibrillation current, PEEP should either be minimised prior to defibrillation or consideration should be given to earlier use of high energy levels for defibrillation...
- Effects of respiratory gas composition on transthoracic impedance
C D Deakin
Department of Anaesthesia, Southampton University Hospitals NHS Trust, Southampton General Hospital, UK
Resuscitation 38:193-5. 1998
..Therefore transthoracic current during defibrillation is unlikely to be affected by different respiratory gases. This is the first study to document that these respiratory gases do not change the impedance of transthoracic pathways...
- A comparison of transthoracic impedance using standard defibrillation paddles and self-adhesive defibrillation pads
C D Deakin
Department of Anaesthesia, Southampton University Hospitals, NHS Trust, Southampton General Hospital, UK
Resuscitation 39:43-6. 1998
..TTI in group D is significantly larger. Although transmyocardial current is related to TTI, the relationship is complex and differences in TTI alone cannot predict the outcome from defibrillation...
- Thermal energy balance as a measure of adequate rewarming from hypothermic cardiopulmonary bypass
C D Deakin
Department of Anaesthetics, Southampton General Hospital, England
J Cardiothorac Vasc Anesth 14:388-92. 2000
..To determine whether the amount of heat (thermal energy) used actively to rewarm patients on cardiopulmonary bypass (CPB) was a better indicator of adequate rewarming from hypothermic CPB than core temperature...
- How often should defibrillation pads be changed?: the effect of evaporative drying
C D Deakin
Department of Anaesthesia, Southampton University Hospitals NHS Trust, UK
Resuscitation 48:157-62. 2001
..This study was carried out to assess the effect of evaporative drying of defibrillation pads on TTI...
- Autotransfusion of washed shed mediastinal fluid decreases the requirement for autologous blood transfusion following cardiac surgery: a prospective randomized trial
M J Dalrymple-Hay
Wessex Cardiothoracic Centre, Department of Cardiothoracic Surgery, Southampton General Hospital, UK
Eur J Cardiothorac Surg 15:830-4. 1999
..Transfusion reactions, infection risk and cost should stimulate us to decrease this transfusion rate. We test the efficacy of autotransfusion following surgery in a prospective randomized trial...
- Do physiological changes in pregnancy change defibrillation energy requirements?
J Nanson
Shackleton Department of Anaesthesia, Southampton University Hospital NHS Trust, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK
Br J Anaesth 87:237-9. 2001
..3 (15.8) Omega at term and 91.6 (11.8) Omega 6-8 weeks after delivery; the difference was not statistically significant. We conclude that current energy requirements for adult defibrillation are appropriate for use during pregnancy...
- Evidence-based guidelines for the use of defibrillation pads
N E Drury
Shackleton Department of Anaesthetics, Southampton University Hospitals NHS Trust, SO16 6YD, Southampton, UK
Resuscitation 51:283-6. 2001
..CONCLUSIONS: Defibrillation pads can be used for up to 30 min without evaporation causing a clinically significant increase in TTI. The passage of a defibrillation current across pads does not further accelerate water loss...
- Haemodynamic effects of descending aortic occlusion during cardiopulmonary resuscitation
C D Deakin
Department of Anaesthetics, Southampton General Hospital, UK
Resuscitation 33:49-52. 1996
..Animal studies are consistent with these findings and show that aortic occlusion may significantly improve outcome from cardiac arrest...
