Genomes and Genes


Richarda M de Voer



  1. Grolleman J, de Voer R, Elsayed F, Nielsen M, Weren R, Palles C, et al. Mutational Signature Analysis Reveals NTHL1 Deficiency to Cause a Multi-tumor Phenotype. Cancer Cell. 2019;35:256-266.e5 pubmed publisher
    ..These results reveal NTHL1 as a multi-tumor predisposition gene with a high lifetime risk for extracolonic cancers and a typical mutational signature observed across tumor types, which can assist in the recognition of this syndrome. ..
  2. Hahn M, Vreede L, Bemelmans S, van der Looij E, van Kessel A, Schackert H, et al. Prevalence of germline mutations in the spindle assembly checkpoint gene BUB1B in individuals with early-onset colorectal cancer. Genes Chromosomes Cancer. 2016;55:855-63 pubmed publisher
    ..2016 Wiley Periodicals, Inc. ..