J F Dawson

Summary

Publications

  1. ncbi request reprint Molecular mechanisms underlying inhibition of protein phosphatases by marine toxins
    J F Dawson
    MRC Protein Structure and Function Group, Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada T6G 2H7
    Front Biosci 4:D646-58. 1999
  2. ncbi request reprint Identification of sds21 in fission yeast in an inhibitor-resistant high molecular mass protein phosphatase-1 complex
    J F Dawson
    Department of Biochemistry, University of Alberta, Edmonton, Canada
    Biochem Cell Biol 77:551-8. 1999
  3. ncbi request reprint Mutation of the toxin binding site of PP-1c: comparison with PP-2B
    J F Dawson
    Department of Biochemistry, University of Alberta, Edmonton, Alberta, T6G 2H7, Canada
    Biochem Biophys Res Commun 270:543-9. 2000
  4. ncbi request reprint Inhibition of protein phosphatase-1 by clavosines A and B. Novel members of the calyculin family of toxins
    T L McCready
    Department of Biochemistry, University of Alberta, Edmonton, Alberta T6G 2H7, Canada
    J Biol Chem 275:4192-8. 2000
  5. ncbi request reprint Identification and characterization of cAMP-dependent protein kinase and its possible direct interactions with protein phosphatase-1 in marine dinoflagellates
    J F Dawson
    Department of Biochemistry, University of Alberta, Edmonton, Canada
    Biochem Cell Biol 74:559-67. 1996
  6. ncbi request reprint Molecular enzymology underlying regulation of protein phosphatase-1 by natural toxins
    C F B Holmes
    CIHR Group in Protein Structure and Function, Department of Biochemistry, University of Alberta, Edmonton, Alberta, T6G 2H7, Canada
    Curr Med Chem 9:1981-9. 2002

Detail Information

Publications6

  1. ncbi request reprint Molecular mechanisms underlying inhibition of protein phosphatases by marine toxins
    J F Dawson
    MRC Protein Structure and Function Group, Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada T6G 2H7
    Front Biosci 4:D646-58. 1999
    ....
  2. ncbi request reprint Identification of sds21 in fission yeast in an inhibitor-resistant high molecular mass protein phosphatase-1 complex
    J F Dawson
    Department of Biochemistry, University of Alberta, Edmonton, Canada
    Biochem Cell Biol 77:551-8. 1999
    ..However, this study demonstrated that recombinant sds21 is not a target for PKA in vitro. The constrained configuration of the putative PKA site on the PP-1 holoenzyme may restrict its ability to be targeted by PKA...
  3. ncbi request reprint Mutation of the toxin binding site of PP-1c: comparison with PP-2B
    J F Dawson
    Department of Biochemistry, University of Alberta, Edmonton, Alberta, T6G 2H7, Canada
    Biochem Biophys Res Commun 270:543-9. 2000
    ..We hypothesize that an interaction outside the catalytic core causing the L7 loop of PP-2B to block the catalytic site may be responsible for PP-2B resistance to toxins...
  4. ncbi request reprint Inhibition of protein phosphatase-1 by clavosines A and B. Novel members of the calyculin family of toxins
    T L McCready
    Department of Biochemistry, University of Alberta, Edmonton, Alberta T6G 2H7, Canada
    J Biol Chem 275:4192-8. 2000
    ....
  5. ncbi request reprint Identification and characterization of cAMP-dependent protein kinase and its possible direct interactions with protein phosphatase-1 in marine dinoflagellates
    J F Dawson
    Department of Biochemistry, University of Alberta, Edmonton, Canada
    Biochem Cell Biol 74:559-67. 1996
    ..Higher eukaryotes may have developed inhibitor proteins to provide more complex regulation of protein phosphatase activity...
  6. ncbi request reprint Molecular enzymology underlying regulation of protein phosphatase-1 by natural toxins
    C F B Holmes
    CIHR Group in Protein Structure and Function, Department of Biochemistry, University of Alberta, Edmonton, Alberta, T6G 2H7, Canada
    Curr Med Chem 9:1981-9. 2002
    ....