Michael Davidson

..The purpose of the present study was to compare the effect of haloperidol with that of second-generation antipsychotic drugs on the cognitive performance of patients with schizophreniform disorder or first-episode schizophrenia...

..Impairments in intellectual functioning and abnormal behaviors leading to mental illnesses may share common neurobiological substrates. The results support screening male adolescents with learning disorders for psychopathology...

..The present study explored the association between refractive errors in adolescence and schizophrenia, and the potential familiality of this association...

..Previous work suggests that the association between urbanicity and schizophrenia may be greatest in those with pre-existing vulnerability...

..Further, cognitive improvement associated with treatment with risperidone was not influenced by changes in symptoms, but that relationship was significant in haloperidol-treated patients...

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..The authors tested the CMAI factor structure by use of data from three samples of nursing home patients categorized a priori as having at least mild behavioral and psychological symptoms of dementia...

..Investigating the relationship between premorbid functioning and treatment response in schizophrenia is relevant to understanding the illness and predicting treatment outcomes...

..We investigated cognitive performance on a large, population-based sample of individuals, affected at the time of testing by nonpsychotic disorders, and their unaffected siblings...

..To test this hypothesis, we examined the association between parental age at birth and the social functioning of their adolescent male offspring in a population-based study...

..In a historical-prospective design, we studied the association between dysthymia in adolescence and later hospitalization for psychotic disorders and schizophrenia...

..In the long term, risperidone prevents relapse in more patients and for a longer time and also induces less abnormal movements than haloperidol...

..This study examined the premorbid behavioral and intellectual functioning of schizophrenia patients who showed poor response to antipsychotic treatment...

..The assumption behind this is that most individuals with schizophrenia will be hospitalized at least once in their life-time...

..It has been suggested that attenuated psychotic symptoms (APSs) reported by people who do not have psychotic disorders signal risk for later severe mental illness...

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..A decline between ages 16 and 17 and the onset of psychosis is evident in some but not all cognitive functions...

..Empirical support for this hypothesis comes primarily from small samples using retrospectively collected data...

..Although there are some disadvantages to research based on clinical registries, this method enables study designs not be possible with conventional research paradigms...

..We sought to contribute to this debate by linking data on persons who had been hospitalized for meningitis as children, with a National Psychiatric Hospitalization Registry...

..To examine the effect of risperidone on specific behavioral and psychological symptoms of dementia (BPSD)...

..Alternatively, this may indicate that the effect of the medication may involve lipid metabolism, rather than other proposed mechanisms...

..309-3.104. CONCLUSIONS: In this cohort of male adolescents with behavior disturbances, these results further support the hypothesis that drug abuse may be associated with increased risk for future schizophrenia...

..As up to 50% of the general population will be affected during their lifetime by a condition defined in DSM IV as psychopathology, due to this much higher base rate, factors increasing risk by 2-3 fold might become clinically relevant...

..This study assessed the sensitivity of the diagnosis of psychotic disorders ( International Statistical Classification of Diseases, 10th Revision [ ICD-10 ] F20.0-F29.9) and schizophrenia ( ICD-10 F20.0-F20.9) in the Registry...

..Thus, it is not clear to what extent results are generalizable to most individuals treated for a psychotic illness who may not be eligible for such trials...

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..The present study investigated possible differences in levels of these lipids in AD patients, with or without cardiovascular diseases or risk factors...

..Clinicians must not only be aware of the modifiable risk factors, but they must also learn to manage the obstacles to prevention in conjunction with other health care specialists...