A randomized, double-blind, placebo-controlled phase 3 study of the relative efficacy and tolerability of tapentadol IR and oxycodone IR for acute painStephen Daniels
Premier Research, Austin, TX, USA
Curr Med Res Opin 25:1551-61. 2009
..To evaluate the relative efficacy and tolerability of tapentadol immediate release (IR) and oxycodone IR for management of moderate to severe pain following orthopedic surgery (bunionectomy)...
- Diclofenac potassium liquid-filled soft gelatin capsules for the treatment of postbunionectomy pain
Stephen E Daniels
Premier Research Group, Ltd, Austin, TX 78666, USA
Curr Med Res Opin 26:2375-84. 2010
..The objective of this study was to investigate the efficacy and safety of DPSGC 25 mg in a multicenter, randomized, double-blind, placebo-controlled study in patients experiencing pain following first metatarsal bunionectomy...
- An assessment of the efficacy and safety of diclofenac potassium liquid-filled capsules in patients with various levels of baseline pain intensity
Stephen E Daniels
Premier Research Group Ltd, Austin, TX 78666, USA
Curr Med Res Opin 28:953-61. 2012
..Diclofenac potassium liquid-filled soft gelatin capsule (DPSGC; Zipsor*) is a novel formulation of diclofenac potassium used to treat mild to moderate acute pain...
Clinical efficacy and safety of tapentadol immediate release in the postoperative settingStephen E Daniels
Premier Research Group, Austin, TX, USA
J Am Podiatr Med Assoc 102:139-48. 2012
..Therefore, tapentadol immediate release may offer an improved analgesic option for the relief of postoperative pain after podiatric surgery...
- Evaluation of the dose range of etoricoxib in an acute pain setting using the postoperative dental pain model
Stephen E Daniels
Premier Research Group, 3200 Red River Boulevard, Austin, TX 78705, USA
Clin J Pain 27:1-8. 2011
..This study was conducted to evaluate the dose range of etoricoxib in acute pain using the postoperative dental pain model further...
- Efficacy and safety of oxycodone HCl/niacin tablets for the treatment of moderate-to-severe postoperative pain following bunionectomy surgery
Stephen E Daniels
Premier Research Group, Austin, Texas 78705, USA
Curr Med Res Opin 27:593-603. 2011
..To evaluate the efficacy and safety of two dose strengths of oxycodone hydrochloride (HCl)/niacin tablets * for the treatment of moderate-to-severe postoperative pain following bunionectomy surgery...
- Efficacy and tolerability of lumiracoxib 200 mg once daily for treatment of primary dysmenorrhea: results from two randomized controlled trials
Stephen Daniels
SCIREX Clinical Research Centers, Austin, TX 78705, USA
J Womens Health (Larchmt) 17:423-37. 2008
..However, the efficacy and tolerability of lumiracoxib 200 mg once daily (q.d.) has not previously been examined in primary dysmenorrhea...
- Celecoxib in the treatment of primary dysmenorrhea: results from two randomized, double-blind, active- and placebo-controlled, crossover studies
Stephen Daniels
ClinicaI Research Centers Premier Research Group Ltd formerly Scirex Clinical Research Centers, Austin, Texas 78705, USA
Clin Ther 31:1192-208. 2009
..Celecoxib, a cyclooxygenase-2 inhibitor, has established analgesic efficacy for the treatment of acute pain resulting from a variety of causes...
- A randomised, five-parallel-group, placebo-controlled trial comparing the efficacy and tolerability of analgesic combinations including a novel single-tablet combination of ibuprofen/paracetamol for postoperative dental pain
Stephen E Daniels
Premier Research, Austin, TX 78705, USA
Pain 152:632-42. 2011
..A single-tablet combination of ibuprofen 200mg/paracetamol 500mg provides highly effective analgesia, comparable or superior to other combination analgesics indicated for strong pain...
- A double-blind randomized controlled trial of rofecoxib and multidose oxycodone/acetaminophen in dental impaction pain
Paul J Desjardins
Clinical Research and Clinical Site Operations, SCIREX Clinical Research Centers, Austin, TX 78705, USA
J Oral Maxillofac Surg 65:1624-32. 2007
- Valdecoxib, a cyclooxygenase-2-specific inhibitor, is effective in treating primary dysmenorrhea
Stephen E Daniels
From the Scirex Corporation, Austin, Texas, USA
Obstet Gynecol 100:350-8. 2002
..Valdecoxib 20 mg and 40 mg demonstrate analgesic efficacy, based on onset, magnitude, and duration of analgesia that is similar to naproxen sodium, making it a potential choice for treating women with primary dysmenorrhea...
Valdecoxib for treatment of primary dysmenorrhea. A randomized, double-blind comparison with placebo and naproxenStephen E Daniels
SCIREX Corporation, 3200 Red River, Suite 300, Austin, TX 78705, USA
J Gen Intern Med 20:62-7. 2005
..To compare the analgesic efficacy of valdecoxib with placebo and naproxen sodium for relieving menstrual cramping and pain due to primary dysmenorrhea...
- Rofecoxib 50 mg and valdecoxib 20 or 40 mg in adults and adolescents with postoperative pain after third molar extraction: results of two randomized, double-blind, placebo-controlled, single-dose studies
Stephen E Daniels
SCIREX Corporation, Austin, Texas 78705, USA
Clin Ther 28:1022-34. 2006
..These studies assessed the comparative efficacy of rofecoxib and valdecoxib in the treatment of acute postoperative dental pain...
- The analgesic efficacy of valdecoxib vs. oxycodone/acetaminophen after oral surgery
Stephen E Daniels
Clinical Site Operations, SCIREX Corp, Austin, Texas, USA
J Am Dent Assoc 133:611-21; quiz 625. 2002
..The studies reported here suggest that the COX-2-specific inhibitor valdecoxib offers an efficacious and safe alternative to other analgesics used to treat pain after oral surgery...
- A randomized, double-blind, phase III study comparing multiple doses of tapentadol IR, oxycodone IR, and placebo for postoperative (bunionectomy) pain
Stephen E Daniels
Premier Research, Austin, TX, USA
Curr Med Res Opin 25:765-76. 2009
..This study evaluated tapentadol immediate release (IR) for pain relief following orthopedic bunionectomy surgery...
- Single doses of parecoxib sodium intravenously are as effective as ketorolac in reducing pain after oral surgery
Donald R Mehlisch
SCIREX Corporation, Austin, TX, USA
J Oral Maxillofac Surg 61:1030-7. 2003
..Parecoxib sodium appears to be safe and well tolerated and, therefore, merits further evaluation in other models of postsurgical pain...
- A phase 3, randomized, placebo-controlled trial of DepoFoam® bupivacaine (extended-release bupivacaine local analgesic) in bunionectomy
Michael Golf
Premier Clinical Research Centers, Austin, TX, USA
Adv Ther 28:776-88. 2011
..San Diego, CA, USA), an extended-release liposomal bupivacaine-based analgesic, was compared with placebo for the prevention of pain after bunionectomy in a randomized, multicenter, double-blind phase 3 clinical study...
- Onset of analgesia with sodium ibuprofen, ibuprofen acid incorporating poloxamer and acetaminophen--a single-dose, double-blind, placebo-controlled study in patients with post-operative dental pain
Stephen Daniels
Premier Research Group, Clinical Research Center, 3200 Red River, Austin, TX 78705, USA
Eur J Clin Pharmacol 65:343-53. 2009
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- Analgesic efficacy of etoricoxib in primary dysmenorrhea: results of a randomized, controlled trial
Kerstin Malmstrom
Clinical Immunology and Analgesia, Merck Research Laboratories, Rahway, NJ 07065, USA
Gynecol Obstet Invest 56:65-9. 2003
..To determine the efficacy of etoricoxib in the treatment of primary dysmenorrhea...
