An observational study of the prevalence and incidence of comorbid conditions in older women with breast cancerM D Danese
Epidemiology and Outcomes Research, Outcomes Insights Inc, Westlake Village, USA
Ann Oncol 23:1756-65. 2012
..Longitudinal analyses of comorbid conditions in women with breast cancer are few...
Budget impact model of adding erlotinib to a regimen of gemcitabine for the treatment of locally advanced, nonresectable or metastatic pancreatic cancerMark D Danese
Outcomes Insights, Inc, Newbury Park, California 91320, USA
Clin Ther 30:775-84. 2008
..The aim of this study was to determine the budget impact of adding erlotinib to a US health plan insurer's formulary as a combination therapy with gemcitabine for the treatment of nonresectable pancreatic cancer...
- Consistent control of mineral and bone disorder in incident hemodialysis patients
Mark D Danese
Outcomes Insights, Inc, Newbury Park, California, USA
Clin J Am Soc Nephrol 3:1423-9. 2008
..In 2003, the National Kidney Foundation introduced guidelines for the control of parathyroid hormone, calcium, and phosphorus in hemodialysis patients...
Effect of adherence on lifetime fractures in osteoporotic women treated with daily and weekly bisphosphonatesMark D Danese
Outcomes Insights, Westlake Village, California, USA
J Bone Miner Res 24:1819-26. 2009
..These results show that there is implicit value to improving adherence, both from a financial and clinical perspective...
- Cost and mortality associated with hospitalizations in patients with immune thrombocytopenic purpura
Mark D Danese
Outcomes Insights, Inc, Newbury Park, California, USA
Am J Hematol 84:631-5. 2009
..ITP was associated with higher costs, longer stays, and more in-hospital deaths on average than all other hospitalized patients combined...
- Estimating recurrences prevented from using trastuzumab in HER-2/neu-positive adjuvant breast cancer in the United States
Mark D Danese
Outcomes Insights, Inc, Newbury Park, California, USA
Cancer 116:5575-83. 2010
..Patients with early stage HER2+ tumors are at increased risk of recurrence. The use of trastuzumab for these patients has been shown to reduce recurrences and improve overall survival...
- An observational study of outcomes after initial infused therapy in Medicare patients diagnosed with chronic lymphocytic leukemia
Mark D Danese
Outcomes Insights Inc, 340 N Westlake Blvd, Westlake Village, CA 91362, USA
Blood 117:3505-13. 2011
..These analyses, based on observational data, suggest that the benefits of initial therapy with rituximab in a heterogeneous group of older CLL patients are comparable with those demonstrated in younger patients...
- Addition of rituximab to chemotherapy alone as first-line therapy improves overall survival in elderly patients with mantle cell lymphoma
Robert Griffiths
Outcomes Insights Inc, Westlake Village, CA, USA
Blood 118:4808-16. 2011
..We conclude that first-line chemotherapy including rituximab is associated with significantly improved survival in older patients diagnosed with MCL...
- Racial differences in treatment and survival in older patients with diffuse large B-cell lymphoma (DLBCL)
Robert Griffiths
Outcomes Insights, Inc, Westlake Village, CA, USA
BMC Cancer 10:625. 2010
..Although it is an aggressive type of lymphoma, 40% to 50% of patients are cured with treatment. The study objectives were to identify patient factors associated with treatment and survival in DLBCL...
