Spontaneous osteoclast formation from peripheral blood mononuclear cells in postmenopausal osteoporosisPatrizia D'Amelio
Department of Internal Medicine, Center on Experimental Medicine CeRMS, University of Torino, Turin, Italy
FASEB J 19:410-2. 2005
..Our data demonstrated an increased spontaneous osteoclastogenesis in women affected by postmenopausal osteoporosis: this increase may be explained by the higher production of TNF-alpha and RANKL by PBMC cultures of osteoporotic patients...
- Effects of lifestyle and risk factors on bone mineral density in a cohort of Italian women: suggestion for a new decision rule
P D'Amelio
Department of Internal Medicine, University of Torino, Corso Dogliotti 14, 10126 Torino, Italy
Calcif Tissue Int 77:72-8. 2005
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Teriparatide increases the maturation of circulating osteoblast precursorsP D'Amelio
Department of Surgical and Medical Disciplines Gerontology Section, University of Torino Italy, Corso Bramante 88 90, 10126 Torino, Italy
Osteoporos Int 23:1245-53. 2012
..This study shows that teriparatide promotes the circulating osteoblast (OB) precursor degree of maturation in patients affected by postmenopausal osteoporosis...
- Platelet vitamin D receptor is reduced in osteoporotic patients
P D'Amelio
Section of Gerontology, Department of Surgical and Medical Disciplines, University of Turin, Turin, Italy
Panminerva Med 54:225-31. 2012
..In the present study we evaluate PLTs' VDR expression in osteoporotic as opposed to healthy subjects...
- HDL cholesterol and bone mineral density in normal-weight postmenopausal women: is there any possible association?
P D'Amelio
Department of Internal Medicine, University of Turin, Turin, Italy
Panminerva Med 50:89-96. 2008
..Epidemiological investigation of the association between lipid profile, atherosclerosis and bone mass has produced conflicting..
- Protein intake: the impact on calcium and bone homeostasis
G Isaia
Department of Internal Medicine, University of Turin, 10126 Turin, Italy
J Endocrinol Invest 30:48-53. 2007
..The role of protein intake on bone health is still controversial: this review is focused on the relation between protein intake and bone metabolism...
- Alendronate reduces osteoclast precursors in osteoporosis
P D'Amelio
Gerontology Section, Department of Surgical and Medical Disciplines, University of Torino, Corso Bramante 88 90, 10126, Torino, Italy
Osteoporos Int 21:1741-50. 2010
..We suggest that it acts on mature bone resorbing osteoclasts after 3 months of treatment, whereas, after 1 year, it diminishes their formation by reducing their precursors and serum RANKL...
- Clinical characteristics and incidence of first fracture in a consecutive sample of post-menopausal women attending osteoporosis centers: The PROTEO-1 study
G C Isaia
Gerontology Section, Department of Surgical and Medical Disciplines, University of Turin, Turin, Italy
J Endocrinol Invest 34:534-40. 2011
..Osteoporosis is a highly prevalent disease and fractures are a major cause of disability and morbidity...
- Bone and bone marrow pro-osteoclastogenic cytokines are up-regulated in osteoporosis fragility fractures
P D'Amelio
Gerontology Section, Department of Surgical and Medical Disciplines, University of Torino, Corso Bramante 88 90, Torino, Italy
Osteoporos Int 22:2869-77. 2011
..We demonstrate that the cytokine pattern is shifted towards osteoclast activation and osteoblast inhibition in patients with osteoporotic fractures...
- The osteoprotegerin/RANK/RANKL system: a bone key to vascular disease
P D'Amelio
Department of Surgical and Medical Disciplines, University of Turin, Turin, Italy
J Endocrinol Invest 32:6-9. 2009
..This review aims to report the recent findings on the relationship between osteoporosis and OPG/RANK/RANKL-mediated vascular disease...
- Is leptin the link between fat and bone mass?
G C Isaia
Department of Internal Medicine, University of Turin, Turin, Italy
J Endocrinol Invest 28:61-5. 2005
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