Yifan Dai

Summary

Publications

  1. ncbi Targeted disruption of the alpha1,3-galactosyltransferase gene in cloned pigs
    Yifan Dai
    PPL Therapeutics Inc, 1700 Kraft Drive, Blacksburg, VA 24060, USA
    Nat Biotechnol 20:251-5. 2002
  2. pmc Production of alpha 1,3-galactosyltransferase-deficient pigs
    Carol J Phelps
    PPL Therapeutics Inc, 1700 Kraft Drive, Blacksburg, VA 24060, USA
    Science 299:411-4. 2003
  3. ncbi Efficient production of transgenic cloned calves using preimplantation screening
    Shu Hung Chen
    PPL Therapeutics Inc, Blacksburg, Virginia 24060, USA
    Biol Reprod 67:1488-92. 2002
  4. pmc Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneys
    Gang Chen
    1 Department of Surgery, University of Western Ontario, London, Ontario N6A 5C1, Canada
    Nat Med 11:1295-8. 2005
  5. pmc Generation of cloned transgenic pigs rich in omega-3 fatty acids
    Liangxue Lai
    Division of Animal Science, University of Missouri Columbia, Columbia, Missouri 65211, USA
    Nat Biotechnol 24:435-6. 2006
  6. ncbi Cloned transgenic swine via in vitro production and cryopreservation
    Rongfeng Li
    Division of Animal Science, University of Missouri Columbia, Columbia, Missouri 65211, USA
    Biol Reprod 75:226-30. 2006
  7. doi Expression of the fat-1 gene diminishes prostate cancer growth in vivo through enhancing apoptosis and inhibiting GSK-3 beta phosphorylation
    Yi Lu
    Department of Medicine, University of Pittsburgh, VA Pittsburgh Healthcare Systems, Room 2E146, University Drive, Pittsburgh, PA 15240, USA
    Mol Cancer Ther 7:3203-11. 2008

Collaborators

Detail Information

Publications7

  1. ncbi Targeted disruption of the alpha1,3-galactosyltransferase gene in cloned pigs
    Yifan Dai
    PPL Therapeutics Inc, 1700 Kraft Drive, Blacksburg, VA 24060, USA
    Nat Biotechnol 20:251-5. 2002
    ..Using cells from one colony, we produced six cloned female piglets, of which five were of normal weight and apparently healthy. Southern blot analysis confirmed that these five piglets contain one disrupted pig alpha1,3GT allele...
  2. pmc Production of alpha 1,3-galactosyltransferase-deficient pigs
    Carol J Phelps
    PPL Therapeutics Inc, 1700 Kraft Drive, Blacksburg, VA 24060, USA
    Science 299:411-4. 2003
    ....
  3. ncbi Efficient production of transgenic cloned calves using preimplantation screening
    Shu Hung Chen
    PPL Therapeutics Inc, Blacksburg, Virginia 24060, USA
    Biol Reprod 67:1488-92. 2002
    ..The results suggest that both selection methods are useful for detecting transgenic NT embryos without negatively affecting their development into viable transgenic offspring...
  4. pmc Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneys
    Gang Chen
    1 Department of Surgery, University of Western Ontario, London, Ontario N6A 5C1, Canada
    Nat Med 11:1295-8. 2005
    ..These data suggest that antibodies to non-Gal antigens will present an additional barrier to transplantation of organs from GalT-KO pigs to humans...
  5. pmc Generation of cloned transgenic pigs rich in omega-3 fatty acids
    Liangxue Lai
    Division of Animal Science, University of Missouri Columbia, Columbia, Missouri 65211, USA
    Nat Biotechnol 24:435-6. 2006
    ..The hfat-1 transgenic pigs produce high levels of n-3 fatty acids from n-6 analogs, and their tissues have a significantly reduced ratio of n-6/n-3 fatty acids (P < 0.001)...
  6. ncbi Cloned transgenic swine via in vitro production and cryopreservation
    Rongfeng Li
    Division of Animal Science, University of Missouri Columbia, Columbia, Missouri 65211, USA
    Biol Reprod 75:226-30. 2006
    ..Application of this technique may permit national and international movement of cloned transgenic swine embryos, storage until a suitable surrogate is available, or the long-term frozen storage of valuable genetics...
  7. doi Expression of the fat-1 gene diminishes prostate cancer growth in vivo through enhancing apoptosis and inhibiting GSK-3 beta phosphorylation
    Yi Lu
    Department of Medicine, University of Pittsburgh, VA Pittsburgh Healthcare Systems, Room 2E146, University Drive, Pittsburgh, PA 15240, USA
    Mol Cancer Ther 7:3203-11. 2008
    ..These results suggest that fat-1 gene transfer directly into tumor cells could be used as a novel therapeutic approach...