Ivan Rychlik


Affiliation: Veterinary Research Institute
Country: Czech Republic


  1. Polansky O, Seidlerova Z, Faldynova M, Sisak F, Rychlik I. Protein expression in the liver and blood serum in chickens in response to Salmonella Enteritidis infection. Vet Immunol Immunopathol. 2018;205:10-16 pubmed publisher
    ..Enteritidis infection but not in the liver. Differently abundant proteins characterise the chicken's response to infection and can be also used as markers of chicken health status. ..
  2. Medvecky M, Čejková D, Polansky O, Karasova D, Kubasova T, Cizek A, et al. Whole genome sequencing and function prediction of 133 gut anaerobes isolated from chicken caecum in pure cultures. BMC Genomics. 2018;19:561 pubmed publisher
    ..Major gut microbiota members utilise different strategies for gut colonisation. High oxygen sensitivity of Firmicutes may explain their commonly reported decrease after oxidative burst during gut inflammation. ..
  3. Matulova M, Varmuzova K, Sisak F, Havlickova H, Babak V, Stejskal K, et al. Chicken innate immune response to oral infection with Salmonella enterica serovar Enteritidis. Vet Res. 2013;44:37 pubmed publisher
    ..This points to an important role for immunoglobulins in the restoration of homeostasis in the cecum after infection. ..
  4. Rychlik I, Elsheimer Matulova M, Kyrova K. Gene expression in the chicken caecum in response to infections with non-typhoid Salmonella. Vet Res. 2014;45:119 pubmed publisher
    ..This review outlines the function of individual proteins expressed in chickens after infection with non-typhoid Salmonella serovars. ..
  5. Varmuzova K, Matulova M, Gerzova L, Čejková D, Gardan Salmon D, Panhéleux M, et al. Curcuma and Scutellaria plant extracts protect chickens against inflammation and Salmonella Enteritidis infection. Poult Sci. 2015;94:2049-58 pubmed publisher
    ..The supplementation of chicken feed with extracts from Curcuma and Scutelleria thus may be used in poultry production to effectively decrease gut inflammation and increase chicken performance. ..
  6. Elsheimer Matulova M, Varmuzova K, Kyrova K, Havlickova H, Sisak F, Rahman M, et al. phoP, SPI1, SPI2 and aroA mutants of Salmonella Enteritidis induce a different immune response in chickens. Vet Res. 2015;46:96 pubmed publisher
    ..The differences in interaction between the mutants and chicken host can be used for a more detailed understanding of the chicken immune system. ..
  7. Polansky O, Sekelova Z, Faldynova M, Sebkova A, Sisak F, Rychlik I. Important Metabolic Pathways and Biological Processes Expressed by Chicken Cecal Microbiota. Appl Environ Microbiol. 2015;82:1569-76 pubmed publisher
    ..However, certain care should be taken during microbiota transplantation because the microbiota may behave differently in the intestinal tract of a recipient depending on how well the existing communities are established. ..
  8. Varmuzova K, Faldynova M, Elsheimer Matulova M, Sebkova A, Polansky O, Havlickova H, et al. Immune protection of chickens conferred by a vaccine consisting of attenuated strains of Salmonella Enteritidis, Typhimurium and Infantis. Vet Res. 2016;47:94 pubmed
    ..Adjusting the vaccine composition and changing the administration route therefore affects vaccine efficacy. ..
  9. request reprint
    Rychlik I, Barrow P. Salmonella stress management and its relevance to behaviour during intestinal colonisation and infection. FEMS Microbiol Rev. 2005;29:1021-40 pubmed
    ..The role of quorum-sensing through luxS and sdiA is also considered as a regulator of virulence and colonisation. ..

More Information


  1. Rychlik I, Karasova D, Sebkova A, Volf J, Sisak F, Havlickova H, et al. Virulence potential of five major pathogenicity islands (SPI-1 to SPI-5) of Salmonella enterica serovar Enteritidis for chickens. BMC Microbiol. 2009;9:268 pubmed publisher
    ..e. with the remaining four deleted) and a mutant with all 5 SPIs deleted, and assessed their virulence in one-day-old chickens, together with the innate immune response of this host...
  2. Pavlova B, Volf J, Ondrackova P, Matiasovic J, Stepanova H, Crhanova M, et al. SPI-1-encoded type III secretion system of Salmonella enterica is required for the suppression of porcine alveolar macrophage cytokine expression. Vet Res. 2011;42:16 pubmed publisher
    ..Enteritidis. Our results showed that the SPI-1-encoded T3SS is required not only for cell invasion but in macrophages also for the suppression of early proinflammatory cytokine expression...
  3. Sekelova Z, Stepanova H, Polansky O, Varmuzova K, Faldynova M, Fedr R, et al. Differential protein expression in chicken macrophages and heterophils in vivo following infection with Salmonella Enteritidis. Vet Res. 2017;48:35 pubmed publisher
  4. Volf J, Polansky O, Sekelova Z, Velge P, Schouler C, Kaspers B, et al. Gene expression in the chicken caecum is dependent on microbiota composition. Vet Res. 2017;48:85 pubmed publisher
    ..Gut microbiota and its composition therefore affected protein expression in the chicken caecum though except for immunoglobulin production, the remaining differences were unexpectedly low. ..