Martin Faldyna

Summary

Affiliation: Veterinary Research Institute
Country: Czech Republic

Publications

  1. pmc Porcine mononuclear phagocyte subpopulations in the lung, blood and bone marrow: dynamics during inflammation induced by Actinobacillus pleuropneumoniae
    Petra Ondrackova
    Department of Immunology, Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Vet Res 41:64. 2010
  2. pmc Distribution of porcine monocytes in different lymphoid tissues and the lungs during experimental Actinobacillus pleuropneumoniae infection and the role of chemokines
    Petra Ondrackova
    Veterinary Research Institute, Hudcova 70, Brno 621 00, Czech Republic
    Vet Res 44:98. 2013
  3. doi request reprint Characterization of CD34⁺ thymocytes in newborn dogs
    M Faldyna
    Veterinary Research Institute, Brno, Czech Republic
    Vet Immunol Immunopathol 147:86-90. 2012
  4. doi request reprint Usability of a gamma interferon release assay in the diagnosis of naturally infected pigs with Mycobacterium avium subspecies hominissuis
    Martin Faldyna
    Department of Immunology, Veterinary Research Institute, Brno, Czech Republic
    J Vet Diagn Invest 24:376-8. 2012
  5. ncbi request reprint Lymphatic organ development in dogs: major lymphocyte subsets and activity
    M Faldyna
    Veterinary Research Institute, Hudcova 70, 621 32 Brno, Czech Republic
    Vet Immunol Immunopathol 104:239-47. 2005
  6. ncbi request reprint Experimental Actinobacillus pleuropneumoniae infection in piglets with different types and levels of specific protection: immunophenotypic analysis of lymphocyte subsets in the circulation and respiratory mucosal lymphoid tissue
    M Faldyna
    Department of Immunology, Veterinary Research Institute, Hudcova 70, 621 32 Brno, Czech Republic
    Vet Immunol Immunopathol 107:143-52. 2005
  7. ncbi request reprint A correlation of in vitro tests for the immune response detection: a bovine trichophytosis model
    Martin Faldyna
    Veterinary Research Institute, Brno, Czech Republic
    Vaccine 25:7948-54. 2007
  8. ncbi request reprint Chromium supplementation enhances antibody response to vaccination with tetanus toxoid in cattle
    M Faldyna
    Veterinary Research Institute, Brno, Czech Republic
    J Vet Med B Infect Dis Vet Public Health 50:326-31. 2003
  9. ncbi request reprint Lymphocyte subsets in peripheral blood of dogs--a flow cytometric study
    M Faldyna
    Veterinary Research Institute, Hudcova 70, 621 32, Brno, Czech Republic
    Vet Immunol Immunopathol 82:23-37. 2001
  10. ncbi request reprint Cross-reactive anti-human monoclonal antibodies as a tool for B-cell identification in dogs and pigs
    M Faldyna
    Veterinary Research Institute, Brno, Hudcova 70, 621 00 Brno, Czech Republic
    Vet Immunol Immunopathol 119:56-62. 2007

Collaborators

Detail Information

Publications59

  1. pmc Porcine mononuclear phagocyte subpopulations in the lung, blood and bone marrow: dynamics during inflammation induced by Actinobacillus pleuropneumoniae
    Petra Ondrackova
    Department of Immunology, Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Vet Res 41:64. 2010
    ..In conclusion, two different MP maturation pathways were suggested in pigs. The use of these pathways differs under inflammatory and noninflammatory conditions...
  2. pmc Distribution of porcine monocytes in different lymphoid tissues and the lungs during experimental Actinobacillus pleuropneumoniae infection and the role of chemokines
    Petra Ondrackova
    Veterinary Research Institute, Hudcova 70, Brno 621 00, Czech Republic
    Vet Res 44:98. 2013
    ..In conclusion, "inflammatory" monocytes appear in different lymphoid tissues and the lungs after APP infection in pigs. Various chemokines could drive this process...
  3. doi request reprint Characterization of CD34⁺ thymocytes in newborn dogs
    M Faldyna
    Veterinary Research Institute, Brno, Czech Republic
    Vet Immunol Immunopathol 147:86-90. 2012
    ..T-cell specific markers appear on their surface at early stages of differentiation. As the size of progenitors decreases with terminal primary differentiation, the CD34, CD44, and CD172α surface markers are down-regulated...
  4. doi request reprint Usability of a gamma interferon release assay in the diagnosis of naturally infected pigs with Mycobacterium avium subspecies hominissuis
    Martin Faldyna
    Department of Immunology, Veterinary Research Institute, Brno, Czech Republic
    J Vet Diagn Invest 24:376-8. 2012
    ..The results suggest that the IFN-γ release assay has a higher sensitivity than the tuberculin test and that the assay can be used for diagnosis of M. avium infections in live, naturally infected pigs...
  5. ncbi request reprint Lymphatic organ development in dogs: major lymphocyte subsets and activity
    M Faldyna
    Veterinary Research Institute, Hudcova 70, 621 32 Brno, Czech Republic
    Vet Immunol Immunopathol 104:239-47. 2005
    ..Based on our experimental data, we have concluded that pups are born with a relatively competent immune system the structure of which, however, markedly develops during a few postnatal weeks...
  6. ncbi request reprint Experimental Actinobacillus pleuropneumoniae infection in piglets with different types and levels of specific protection: immunophenotypic analysis of lymphocyte subsets in the circulation and respiratory mucosal lymphoid tissue
    M Faldyna
    Department of Immunology, Veterinary Research Institute, Hudcova 70, 621 32 Brno, Czech Republic
    Vet Immunol Immunopathol 107:143-52. 2005
    ....
  7. ncbi request reprint A correlation of in vitro tests for the immune response detection: a bovine trichophytosis model
    Martin Faldyna
    Veterinary Research Institute, Brno, Czech Republic
    Vaccine 25:7948-54. 2007
    ..Moreover the results show that any of the methods might in future replace the in vivo challenge tests that are still conventionally used for testing of newly developed vaccines...
  8. ncbi request reprint Chromium supplementation enhances antibody response to vaccination with tetanus toxoid in cattle
    M Faldyna
    Veterinary Research Institute, Brno, Czech Republic
    J Vet Med B Infect Dis Vet Public Health 50:326-31. 2003
    ..These results indicate that chromium supplementation at the level used in this experiment modulated the regulation of functions of the immune system...
  9. ncbi request reprint Lymphocyte subsets in peripheral blood of dogs--a flow cytometric study
    M Faldyna
    Veterinary Research Institute, Hudcova 70, 621 32, Brno, Czech Republic
    Vet Immunol Immunopathol 82:23-37. 2001
    ..Therefore, there is need to use appropriate control group in the experimental protocols. Among-breed differences could explain, at least partly, breed predisposition for some diseases...
  10. ncbi request reprint Cross-reactive anti-human monoclonal antibodies as a tool for B-cell identification in dogs and pigs
    M Faldyna
    Veterinary Research Institute, Brno, Hudcova 70, 621 00 Brno, Czech Republic
    Vet Immunol Immunopathol 119:56-62. 2007
    ..The advantages and limits of cross-reactive mAbs in studies on animal B-cells are discussed...
  11. pmc SPI-1-encoded type III secretion system of Salmonella enterica is required for the suppression of porcine alveolar macrophage cytokine expression
    Barbora Pavlova
    Veterinary Research Institute, Brno, Czech Republic
    Vet Res 42:16. 2011
    ..Enteritidis. Our results showed that the SPI-1-encoded T3SS is required not only for cell invasion but in macrophages also for the suppression of early proinflammatory cytokine expression...
  12. ncbi request reprint Immune response of pigs to Salmonella enterica serovar Derby and Typhimurium infections
    Jan Matiasovic
    Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic Electronic address
    Vet Microbiol 170:284-90. 2014
    ..Cellular immune response to both strains was very low and was detected later than was the onset of IgG antibody production. ..
  13. doi request reprint Impact of maternally-derived antibodies against Salmonella enterica serovar Typhimurium on the bacterial load in suckling piglets
    Jan Matiasovic
    Veterinary Research Institute, Hudcova 70, Brno, Czech Republic
    Vet J 196:114-5. 2013
    ..Such a vaccine, delivering colostral/lactogenic immunity to piglets thus has the potential to reduce the prevalence non-typhoid Salmonella spp. infection...
  14. doi request reprint Cell-mediated immune response in swine infected with Mycobacterium avium subsp. avium
    Hana Stepanova
    Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Vet Immunol Immunopathol 142:107-12. 2011
    ..Using flow cytometry, we found that double-positive CD4(+)CD8(+) lymphocytes were the major T lymphocyte subset producing IFN-γ after in vitro re-stimulation...
  15. pmc Influence of 5 major Salmonella pathogenicity islands on NK cell depletion in mice infected with Salmonella enterica serovar Enteritidis
    Daniela Karasova
    Veterinary Research Institute, Hudcova 70, 62100 Brno, Czech Republic
    BMC Microbiol 10:75. 2010
    ..In this study we were interested in the colonisation and early immune response of Balb/C mice to infection with Salmonella Enteritidis and isogenic pathogenicity island free mutants...
  16. ncbi request reprint Phenotypic characterisation of the monocyte subpopulations in healthy adult pigs and Salmonella-infected piglets by seven-colour flow cytometry
    Petra Ondrackova
    Veterinary Research Institute, Brno, Czech Republic
    Res Vet Sci 94:240-5. 2013
    ..In Salmonella-infected piglets, the population of CD14(low) CD163(+) SLA-DR(+) monocytes was elevated in the BM and mesenteric lymph nodes (MLN), suggesting the role of this population in pathogenesis of Salmonella infection in pigs...
  17. ncbi request reprint Different immune response of pigs to Mycobacterium avium subsp. avium and Mycobacterium avium subsp. hominissuis infection
    Hana Stepanova
    Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Vet Microbiol 159:343-50. 2012
    ..In the case of MAH infection, the IFN-γ release assay could fail because of the low immunogenic capacity of the MAH strain...
  18. pmc Host response in rabbits to infection with Pasteurella multocida serogroup F strains originating from fowl cholera
    Zoran Jaglic
    Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Can J Vet Res 75:200-8. 2011
    ..This is the first study directly demonstrating that avian P. multocida serogroup F strains are highly virulent in rabbits and that avian hosts cannot be excluded as a possible source of rabbit infection with serogroup F...
  19. doi request reprint Adenosine modulates LPS-induced cytokine production in porcine monocytes
    Petra Ondrackova
    Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Cytokine 61:953-61. 2013
    ..The results suggest that adenosine plays an important role in modulation of cytokine production by porcine monocytes...
  20. doi request reprint Age-dependent changes of proinflammatory cytokine production by porcine peripheral blood phagocytes
    Petra Zelnickova
    Department of Immunology, Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Vet Immunol Immunopathol 124:367-78. 2008
    ..In conclusion, the ability of porcine blood leukocytes to produce cytokines develops during postnatal life...
  21. doi request reprint Experimental infection of gnotobiotic piglets with Escherichia coli strains positive for EAST1 and AIDA
    Zuzana Sramkova Zajacova
    Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Vet Immunol Immunopathol 152:176-82. 2013
    ..The EAST1 toxin alone was not able to induce diarrhoea in animals. Therefore our results demonstrate that the function/role of EAST1 and AIDA in colibacillosis of pigs remains to be elucidated...
  22. doi request reprint Epidemiology and interaction of Salmonella enterica serovar Derby, Infantis and Typhimurium with porcine alveolar macrophages
    Jiri Volf
    Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Vet Microbiol 146:105-10. 2010
    ..The lower cytokine signaling but higher cytotoxicity of S. Typhimurium for macrophages correlates with the higher virulence for pigs of this serotype when compared with S. Derby or S. Infantis...
  23. doi request reprint Cytokine mRNA expression in porcine cell lines stimulated by enterotoxigenic Escherichia coli
    Barbora Pavlova
    Veterinary Research Institute, Hudcova 70, Brno 621 00, Czech Republic
    Vet Microbiol 132:105-10. 2008
    ..The highest IL-8 and TNF-alpha mRNA expression in 3D4/31 was detected after stimulation with serotype O149:K88 frequently associated with hemorrhagic gastroenteritis...
  24. doi request reprint CD4+ and γδTCR+ T lymphocytes are sources of interleukin-17 in swine
    Hana Stepanova
    Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Cytokine 58:152-7. 2012
    ..We can conclude that only two subpopulations of porcine WBCs are sources of IL-17 after non-specific stimulation: CD3(+)CD4(+) and CD3(+)γδTCR(+)...
  25. pmc SPI-1 encoded genes of Salmonella Typhimurium influence differential polarization of porcine alveolar macrophages in vitro
    Kamila Kyrova
    Veterinary Research Institute, Hudcova Brno, Czech Republic
    BMC Vet Res 8:115. 2012
    ..Some pathogens are capable of interfering with differentiation in order to down-regulate the anti-microbial activity and enhance their survival in the host...
  26. doi request reprint Influence of the lipopolysaccharide structure of Salmonella enterica serovar Enteritidis on interactions with pig neutrophils
    Jan Matiasovic
    Veterinary Research Institute, Hudcova 70, Brno 621 00, Czech Republic
    Vet Microbiol 150:167-72. 2011
    ....
  27. ncbi request reprint Functional development of immune response in rabbits
    Edita Jeklova
    Department of Immunology, Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Vet Immunol Immunopathol 118:221-8. 2007
    ..Nevertheless, significantly lower formation of both isotypes was noted in one-day and two-week-old rabbits, and commencement of IgG isotype formation was delayed in one-day, two-week, and four-week-old rabbits when compared to adults...
  28. doi request reprint Association of attenuated mutants of Salmonella enterica serovar Enteritidis with porcine peripheral blood leukocytes
    Hana Stepanova
    Veterinary Research Institute, Brno, Czech Republic
    FEMS Microbiol Lett 321:37-42. 2011
    ..Enteritidis with porcine leukocytes. This information can be used for the design of live Salmonella vaccines preferentially targeting particular cell types including cancer or tumor cells...
  29. doi request reprint Quantitative nitric oxide production by rat, bovine and porcine macrophages
    Petra Zelnickova
    Department of Immunology, Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Nitric Oxide 19:36-41. 2008
    ..Stimulation of porcine PAM with rIFN-gamma together with LPS led to a significant increase in the expression of NOS II mRNA, albeit without detectable NO production or NOS II expression on the protein level...
  30. doi request reprint Characterisation of immunosuppression in rabbits after infection with myxoma virus
    Edita Jeklova
    Department of Immunology, Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Vet Microbiol 129:117-30. 2008
    ..Presence of MXV in respective lymphoid compartments preceded changes in lymphocyte subset distribution or lymphocyte activity...
  31. ncbi request reprint Experimental study of pathogenicity of Pasteurella multocida serogroup F in rabbits
    Zoran Jaglic
    Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Vet Microbiol 126:168-77. 2008
    ..multocida, serogroup F also can be highly pathogenic for rabbits and therefore might be a cause of considerable economic loss in commercial rabbit production...
  32. doi request reprint Interaction of porcine neutrophils with different strains of enterotoxigenic Escherichia coli
    Petra Ondrackova
    Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Vet Microbiol 160:108-16. 2012
    ..It is suggested that a stronger respiratory burst may be an important factor causing severe clinical signs of post-weaning diarrhea in piglets...
  33. doi request reprint Effects of adjuvants on the immune response of pigs after intradermal administration of antigen
    Josef Krejci
    Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Res Vet Sci 94:73-6. 2013
    ..The oil adjuvants also enhanced the cell-mediated immune responses and the levels of local IgA antibodies in the respiratory mucosa. On the other hand, they elicited more pronounced adverse local reactions...
  34. doi request reprint The effect of adenosine on pro-inflammatory cytokine production by porcine T cells
    Petra Ondrackova
    Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Vet Immunol Immunopathol 145:332-9. 2012
    ..Non-selective antagonist CGS15943 as well as allosteric modulator SCH202676 failed to reverse the effect of NECA in pigs. In conclusion, NECA has an anti-inflammatory effect on porcine T cell subpopulations...
  35. doi request reprint Transfer of humoral and cell-mediated immunity via colostrum in pigs
    Katerina Nechvatalova
    Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Vet Immunol Immunopathol 142:95-100. 2011
    ..Furthermore, we found that antigen-specific lymphocytes were detectable in mesenteric lymph nodes and peripheral blood, but very rarely in spleen and tracheobronchial lymph nodes...
  36. doi request reprint Dexamethasone-induced immunosuppression: a rabbit model
    Edita Jeklova
    Department of Immunology, Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Vet Immunol Immunopathol 122:231-40. 2008
    ..The present results demonstrate clearly that this DXP application protocol is useful for the experimental induction of relatively short-lasting immunosuppression in rabbits...
  37. doi request reprint Usefulness of detection of specific IgM and IgG antibodies for diagnosis of clinical encephalitozoonosis in pet rabbits
    Edita Jeklova
    Department of Immunology, Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Vet Parasitol 170:143-8. 2010
    ..cuniculi, and even in asymptomatic rabbits, detection of both isotypes of specific antibodies should be a routine part of a health check in rabbits...
  38. ncbi request reprint Commercially available rabbit anti-human polyclonal antisera as a useful tool for immune system studies in veterinary species
    J Sinkora
    Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Vet Immunol Immunopathol 119:156-62. 2007
    ..Altogether, our study show that carefully selected polyclonal antibodies available on the market may possess broad cross-reactivity with important applications in veterinary research...
  39. ncbi request reprint Interleukin-17 in veterinary animal species and its role in various diseases: a review
    Marketa Mensikova
    Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Cytokine 64:11-7. 2013
    ..In recent years, some experiments with other animals in which interleukin-17 was measured were carried out. This review is focused on the findings that have been observed and described in important veterinary species of animals...
  40. ncbi request reprint Lymphoid organ development in rabbits: major lymphocyte subsets
    Edita Jeklova
    Department of Immunology, Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Dev Comp Immunol 31:632-44. 2007
    ..Another significant feature was the increase of B cells in peripheral blood and mesenteric lymph nodes...
  41. ncbi request reprint Intracellular cytokine detection by flow cytometry in pigs: fixation, permeabilization and cell surface staining
    Petra Zelnickova
    Department of Immunology, Veterinary Research Institute, Brno, Czech Republic
    J Immunol Methods 327:18-29. 2007
    ..The present study can serve as a particular protocol of intracellular cytokine detection and as a suggestion for optimization of the fixation, permeabilization and cell surface staining procedure in any laboratory...
  42. ncbi request reprint Flow cytometric analysis of bone marrow leukocytes in neonatal dogs
    Martin Faldyna
    Veterinary Research Institute, Brno, Czech Republic
    Vet Immunol Immunopathol 95:165-76. 2003
    ..Using cross-reactive antibodies against CD79alpha we have shown that the B lineage of hematopoiesis strongly prevails. CD34+ cells were shown to be positive for MHC class II and SWC3, a member of the signal regulatory protein family...
  43. ncbi request reprint Systemic and local antibody responses after experimental infection with Actinobacillus pleuropneumoniae in piglets with passive or active immunity
    J Krejci
    Veterinary Research Institute, Hudcova 70, 621 32 Brno, Czech Republic
    J Vet Med B Infect Dis Vet Public Health 52:190-6. 2005
    ..The specific antibodies of IgG isotype increased only in BALF from piglets without colostrum-derived antibodies...
  44. ncbi request reprint Effects of certain inducers of leukocytes migration into the bovine mammary gland on neutrophil apoptosis manifestation in a subsequent in vitro cultivation
    D Rysanek
    Department of Dairy Science and Pathophysiology of Mammary Gland, Veterinary Research Institute, Brno, Czech Republic
    Physiol Res 54:305-12. 2005
    ....
  45. ncbi request reprint Postnatal development of leukocyte subset composition and activity in dogs
    M Toman
    Veterinary Research Institute, Hudcova 70, 62132 Brno, Czech Republic
    Vet Immunol Immunopathol 87:321-6. 2002
    ..Nevertheless its development continues in the postnatal period and some parameters differ from adult values for at least 3 months after birth...
  46. ncbi request reprint Activation of phagocytes during initiation and resolution of mammary gland injury induced by lipopolysaccharide in heifers
    Zbysek Sladek
    Department of Morphology, Physiology and Veterinary Sciences, Mendel University of Agriculture and Forestry, Brno, Czech Republic
    Vet Res 33:191-204. 2002
    ..01). The activation of macrophages during resolution of mammary gland injury can be interpreted as an important mechanism of restitution...
  47. doi request reprint Ovarian disorders in immature rats after postnatal exposure to environmental polycyclic aromatic hydrocarbons
    Vladimir Kummer
    Veterinary Research Institute, Brno, Czech Republic
    J Appl Toxicol 33:90-9. 2013
    ..The study showed that postnatal exposure to BaP, BaA and BkF altered ovarian ERβ expression, disturbed morphological development of the ovaries and caused ovarian dysfunction in immature rats...
  48. doi request reprint The structure and functional analysis of canine T-cell receptor beta region
    Jan Matiasovic
    Veterinary Research Institute, Brno, Czech Republic
    Vet Immunol Immunopathol 132:282-7. 2009
    ..We identified and analyzed probable structure of canine TCR beta region, which is different when compared to sequences published in GenBank or ENSEMBL databases...
  49. ncbi request reprint Morphological and functional disorders of the immature rat uterus after postnatal exposure to benz[a]anthracene and benzo[k]fluoranthene
    Vladimir Kummer
    Veterinary Research Institute, Brno, Czech Republic
    Environ Toxicol Pharmacol 27:253-8. 2009
    ..0μg/kg on postnatal days 20-22) in rats exposed to B[a]A, B[k]F and EE was lower than in controls. The study showed that postnatal exposure to B[a]A and B[k]F resultes in morphological and functional disorders of the immature rat uterus...
  50. ncbi request reprint Early postnatal development of the immune system in piglets: the redistribution of T lymphocyte subsets
    H Stepanova
    Department of Immunology, Veterinary Research Institute, Hudcova 70, 62100 Brno, Czech Republic
    Cell Immunol 249:73-9. 2007
    ..Double positive CD4+CD8+ lymphocytes were rare during the first month of life and a significant age-dependent increase of these cells was found in all the compartments monitored...
  51. ncbi request reprint The influence of culture conditions on the identification of Mycobacterium species by MALDI-TOF MS profiling
    Tereza Balážová
    Research Group Proteomics, CEITEC Central European Institute of Technology, Masaryk University, Brno, Czech Republic Department of Microbiology, Faculty of Science, Masaryk University, Brno, Czech Republic
    FEMS Microbiol Lett 353:77-84. 2014
    ....
  52. ncbi request reprint Effect of postnatal exposure to benzo[a]pyrene on the uterus of immature rats
    Vladimir Kummer
    Veterinary Research Institute, Brno, Czech Republic
    Exp Toxicol Pathol 59:69-76. 2007
    ..The present study showed that postnatal exposure to B[a]P caused pathological changes in constitution and maturation of uterine ERalpha resulting in disturbed morphological development and uterine dysfunction in immature rats...
  53. ncbi request reprint Ontogeny of reactive nitrogen species production by blood phagocytes in pigs
    P Zelnickova
    Veterinary Research Institute, Department of Immunology, Brno, Czech Republic
    Physiol Res 57:81-8. 2008
    ..A temporary increase in all parameters occurred after weaning, but without any significance. In conclusion, RNS production has a decreasing trend during ontogeny and is transiently upregulated after weaning...
  54. doi request reprint Age-related changes in selected haematology parameters in rabbits
    E Jeklova
    Department of Immunology, Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Res Vet Sci 86:525-8. 2009
    ..From the age of six weeks of life, all of the studied haematological parameters were comparable to those of adult rabbits...
  55. ncbi request reprint Cytokine response of porcine cell lines to Salmonella enterica serovar typhimurium and its hilA and ssrA mutants
    J Volf
    Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Zoonoses Public Health 54:286-93. 2007
    ..The ssrA mutant can therefore be considered as more suitable for further vaccine development as the stimulation of innate immune response is important for animal protection against a challenge with virulent strains...
  56. ncbi request reprint Immunosuppression in dogs with pyoderma and/or demodicosis
    M Toman
    Veterinary Research Institute, Brno, Czech Republic
    Vet Med (Praha) 42:299-306. 1997
    ..Conclusion from these findings is that deep pyoderma more than Demodicosis was concerned with immunosuppression. German shepherds with deep pyoderma had more expressed immunosuppression than other breeds...
  57. ncbi request reprint Reactivity of cross-reacting monoclonal antibodies with canine leukocytes, platelets and erythrocytes
    Hans Joachim Schuberth
    Immunology Unit, School of Veterinary Medicine, Bischofsholer Damm 15, D 30173 Hannover, Germany
    Vet Immunol Immunopathol 119:47-55. 2007
    ..In summary, this study confirmed the reactivity of previously described cross-reactive mAbs with canine cells and resulted in the characterization of mAbs recognizing so far undetectable canine CD molecules...
  58. ncbi request reprint HlyA knock out yields a safer Escherichia coli A0 34/86 variant with unaffected colonization capacity in piglets
    Valeria Sheshko
    Laboratory of Molecular Biology of Bacterial Pathogens, Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic
    FEMS Immunol Med Microbiol 48:257-66. 2006
    ..We suggest that the E. coli A0 34/86 Delta hlyA mutant may represent a safer prophylactic and/or immunomodulatory tool with unaffected colonization capacity...
  59. ncbi request reprint Neutrophil apoptosis during experimentally induced Staphylococcus aureus mastitis
    Zbysek Sladek
    Department of Morphology, Physiology and Veterinary Sciences, Mendel University of Agriculture and Forestry, Zemedelska 1, 613 00 Brno, Czech Republic
    Vet Res 36:629-43. 2005
    ..An early inclusion of the mechanisms of an acute inflammatory resolution thus paradoxically led to chronic infection...