Kristina Kejlova

Summary

Affiliation: National Institute of Public Health
Country: Czech Republic

Publications

  1. ncbi request reprint Hydrophilic polymers--biocompatibility testing in vitro
    K Kejlova
    National Reference Center for Cosmetics, National Institute of Public Health, Srobarova 48, 100 42 Prague 10, Czech Republic
    Toxicol In Vitro 19:957-62. 2005
  2. ncbi request reprint Phototoxicity of bergamot oil assessed by in vitro techniques in combination with human patch tests
    K Kejlova
    National Reference Center for Cosmetics, National Institute of Public Health, Srobarova 48, 100 42 Prague 10, Czech Republic
    Toxicol In Vitro 21:1298-303. 2007
  3. doi request reprint Phototoxicity of essential oils intended for cosmetic use
    Kristina Kejlova
    National Institute of Public Health, Srobarova 48, 100 42 Prague 10, Czech Republic
    Toxicol In Vitro 24:2084-9. 2010
  4. ncbi request reprint Phototoxicity of bituminous tars-correspondence between results of 3T3 NRU PT, 3D skin model and experimental human data
    D Jirova
    National Reference Center for Cosmetics, National Institute of Public Health, Srobarova 48, 100 42 Prague 10, Czech Republic
    Toxicol In Vitro 19:931-4. 2005
  5. doi request reprint Comparison of human skin irritation patch test data with in vitro skin irritation assays and animal data
    Dagmar Jirova
    National Institute of Public Health, Srobarova 48, Prague 10, Czech Republic
    Contact Dermatitis 62:109-16. 2010
  6. ncbi request reprint The benefits of the 3T3 NRU test in the safety assessment of cosmetics: long-term experience from pre-marketing testing in the Czech Republic
    D Jirova
    National Reference Centre for Cosmetics National Institute of Public Health, Srobarova 48, 100 42 Prague 10, Czech Republic
    Toxicol In Vitro 17:791-6. 2003
  7. ncbi request reprint In vitro approaches to evaluation of Sun Protection Factor
    H Bendová
    National Institute of Public Health NIPH, Srobarova 48, 100 42 Prague 10, Czech Republic
    Toxicol In Vitro 21:1268-75. 2007

Detail Information

Publications7

  1. ncbi request reprint Hydrophilic polymers--biocompatibility testing in vitro
    K Kejlova
    National Reference Center for Cosmetics, National Institute of Public Health, Srobarova 48, 100 42 Prague 10, Czech Republic
    Toxicol In Vitro 19:957-62. 2005
    ..HEMA polymer showed a beneficial effect against cytotoxicity of an irritant (sodium dodecyl sulfate). The in vitro biocompatibility test results were confirmed by human local skin tolerance testing...
  2. ncbi request reprint Phototoxicity of bergamot oil assessed by in vitro techniques in combination with human patch tests
    K Kejlova
    National Reference Center for Cosmetics, National Institute of Public Health, Srobarova 48, 100 42 Prague 10, Czech Republic
    Toxicol In Vitro 21:1298-303. 2007
    ..Although the study showed the usefulness of the tiered testing strategy, currently, the extrapolation of in vitro results to human situation may be performed only to a limited extent...
  3. doi request reprint Phototoxicity of essential oils intended for cosmetic use
    Kristina Kejlova
    National Institute of Public Health, Srobarova 48, 100 42 Prague 10, Czech Republic
    Toxicol In Vitro 24:2084-9. 2010
    ..A safety factor of 10 should be applied for extrapolation of experimental data from the skin model assay to man...
  4. ncbi request reprint Phototoxicity of bituminous tars-correspondence between results of 3T3 NRU PT, 3D skin model and experimental human data
    D Jirova
    National Reference Center for Cosmetics, National Institute of Public Health, Srobarova 48, 100 42 Prague 10, Czech Republic
    Toxicol In Vitro 19:931-4. 2005
    ..In addition to the results obtained in 3T3 NRU PT, further testing on 3D skin models may better reflect bioavailability of a given chemical in the skin, relevant to the situation in humans...
  5. doi request reprint Comparison of human skin irritation patch test data with in vitro skin irritation assays and animal data
    Dagmar Jirova
    National Institute of Public Health, Srobarova 48, Prague 10, Czech Republic
    Contact Dermatitis 62:109-16. 2010
    ..Efforts to replace the rabbit skin irritation test have been underway for many years, encouraged by the EU Cosmetics Directive and REACH. Recently various in vitro tests have been developed, evaluated and validated...
  6. ncbi request reprint The benefits of the 3T3 NRU test in the safety assessment of cosmetics: long-term experience from pre-marketing testing in the Czech Republic
    D Jirova
    National Reference Centre for Cosmetics National Institute of Public Health, Srobarova 48, 100 42 Prague 10, Czech Republic
    Toxicol In Vitro 17:791-6. 2003
    ..Cytotoxicity tests represent a highly ethical approach for estimation of irritancy. On the basis of in vitro test results suggesting low risk we can proceed to confirmatory tests in human volunteers...
  7. ncbi request reprint In vitro approaches to evaluation of Sun Protection Factor
    H Bendová
    National Institute of Public Health NIPH, Srobarova 48, 100 42 Prague 10, Czech Republic
    Toxicol In Vitro 21:1268-75. 2007
    ..The in vitro screening methods may represent a fast and reasonable tool reducing the number of in vivo experiments and risks related to UV exposure of human subjects, when the technical test parameters are adjusted and optimized...