- Comparison of human skin irritation patch test data with in vitro skin irritation assays and animal dataDagmar Jirova
National Institute of Public Health, Srobarova 48, Prague 10, Czech Republic
Contact Dermatitis 62:109-16. 2010..Efforts to replace the rabbit skin irritation test have been underway for many years, encouraged by the EU Cosmetics Directive and REACH. Recently various in vitro tests have been developed, evaluated and validated...
- Phototoxicity of essential oils intended for cosmetic useKristina Kejlova
National Institute of Public Health, Srobarova 48, 100 42 Prague 10, Czech Republic
Toxicol In Vitro 24:2084-9. 2010..A safety factor of 10 should be applied for extrapolation of experimental data from the skin model assay to man...