I Rektor

Summary

Affiliation: Masaryk University
Country: Czech Republic

Publications

  1. ncbi request reprint The effect of response type (motor output versus mental counting) on the intracerebral distribution of the slow cortical potentials in an externally cued (CNV) paradigm
    Martin Bares
    First Department of Neurology, Masaryk University, St Anne s Hospital, Pekarska 53, 65691 Brno, Czech Republic
    Brain Res Bull 71:428-35. 2007
  2. doi request reprint Perampanel, a novel, non-competitive, selective AMPA receptor antagonist as adjunctive therapy for treatment-resistant partial-onset seizures
    Ivan Rektor
    Masaryk University, Central European Institute of Technology, St Anne s Hospital, Brno Epilepsy Center, First Department of Neurology, Pekarska 53, 656 91 Brno, Czech Republic
    Expert Opin Pharmacother 14:225-35. 2013
  3. doi request reprint Perampanel Study 207: long-term open-label evaluation in patients with epilepsy
    I Rektor
    Brno Epilepsy Centre, First Department of Neurology, St Anne s University Hospital, Masaryk University, Brno, Czech Republic
    Acta Neurol Scand 126:263-9. 2012
  4. doi request reprint Impairment of brain vessels may contribute to mortality in patients with Parkinson's disease
    Ivan Rektor
    Central European Institute of Technology, Brno, Czech Republic
    Mov Disord 27:1169-72. 2012
  5. ncbi request reprint Cognitive- and movement-related potentials recorded in the human basal ganglia
    Ivan Rektor
    First Department of Neurology, Masaryk University, St Anne s Teaching Hospital, Brno, Czech Republic
    Mov Disord 20:562-8. 2005
  6. doi request reprint Cognitive activities in the subthalamic nucleus. Invasive studies
    Ivan Rektor
    First Department of Neurology, Masaryk University, St Anne s Hospital, Brno, Czech Republic
    Parkinsonism Relat Disord 15:S83-6. 2009
  7. doi request reprint High doses of rotigotine transdermal patch: results of an open-label, dose-escalation trial in patients with advanced-stage, idiopathic Parkinson disease
    Ivan Rektor
    First Department of Neurology, Masaryk University, Saint Anne s Hospital, Brno, Czech Republic
    Clin Neuropharmacol 32:193-8. 2009
  8. doi request reprint Secondary generalization in seizures of temporal lobe origin: Ictal EEG pattern in a stereo-EEG study
    Ivan Rektor
    First Department of Neurology, Masaryk University, St Anne s Hospital, Pekarska 53, Brno 656 91, Czech Republic
    Epilepsy Behav 15:235-9. 2009
  9. ncbi request reprint A SEEG study of ERP in motor and premotor cortices and in the basal ganglia
    I Rektor
    1st Department of Neurology, Masaryk University, St Anne s Hospital, Pekarska 53, 656 91 Brno, Czech Republic
    Clin Neurophysiol 114:463-71. 2003
  10. doi request reprint Vascular pathology in patients with idiopathic Parkinson's disease
    Ivan Rektor
    Movement Disorders Centre and Stroke Centre, First Department of Neurology, Masaryk University, St Anne s Teaching Hospital, Pekarska 53, 656 91 Brno, Czech Republic
    Parkinsonism Relat Disord 15:24-9. 2009

Detail Information

Publications98

  1. ncbi request reprint The effect of response type (motor output versus mental counting) on the intracerebral distribution of the slow cortical potentials in an externally cued (CNV) paradigm
    Martin Bares
    First Department of Neurology, Masaryk University, St Anne s Hospital, Pekarska 53, 65691 Brno, Czech Republic
    Brain Res Bull 71:428-35. 2007
    ..This study concerned the intracerebrally located generators of the Contingent Negative Variation in two different paradigm settings: (i) motor output required, (ii) silent counting required (non-motor control condition)...
  2. doi request reprint Perampanel, a novel, non-competitive, selective AMPA receptor antagonist as adjunctive therapy for treatment-resistant partial-onset seizures
    Ivan Rektor
    Masaryk University, Central European Institute of Technology, St Anne s Hospital, Brno Epilepsy Center, First Department of Neurology, Pekarska 53, 656 91 Brno, Czech Republic
    Expert Opin Pharmacother 14:225-35. 2013
    ..This article reviews preclinical and clinical data for 2-(2-oxo-1-phenyl-5-pyridin-2-yl-1,2-dihydropyridin-3-yl)benzonitrile, perampanel , a new chemical entity developed for the treatment of partial-onset seizures...
  3. doi request reprint Perampanel Study 207: long-term open-label evaluation in patients with epilepsy
    I Rektor
    Brno Epilepsy Centre, First Department of Neurology, St Anne s University Hospital, Masaryk University, Brno, Czech Republic
    Acta Neurol Scand 126:263-9. 2012
    ..Evaluate interim long-term tolerability, safety and efficacy of adjunctive perampanel, a novel α-amino-3-hydroxy-5-methyl-5-isoxazolepropionic acid (AMPA)-receptor antagonist, in patients with refractory partial-onset seizures...
  4. doi request reprint Impairment of brain vessels may contribute to mortality in patients with Parkinson's disease
    Ivan Rektor
    Central European Institute of Technology, Brno, Czech Republic
    Mov Disord 27:1169-72. 2012
    ..The effect of brain-vessel pathology on mortality in 57 consecutive PD patients was studied...
  5. ncbi request reprint Cognitive- and movement-related potentials recorded in the human basal ganglia
    Ivan Rektor
    First Department of Neurology, Masaryk University, St Anne s Teaching Hospital, Brno, Czech Republic
    Mov Disord 20:562-8. 2005
    ..This role seems to be nonspecific in terms of stimulus modality and in terms of the cognitive context of the task...
  6. doi request reprint Cognitive activities in the subthalamic nucleus. Invasive studies
    Ivan Rektor
    First Department of Neurology, Masaryk University, St Anne s Hospital, Brno, Czech Republic
    Parkinsonism Relat Disord 15:S83-6. 2009
    ....
  7. doi request reprint High doses of rotigotine transdermal patch: results of an open-label, dose-escalation trial in patients with advanced-stage, idiopathic Parkinson disease
    Ivan Rektor
    First Department of Neurology, Masaryk University, Saint Anne s Hospital, Brno, Czech Republic
    Clin Neuropharmacol 32:193-8. 2009
    ..The objective of the study was to determine the maximal achievable dose of rotigotine by assessing the tolerability of escalating doses of rotigotine transdermal patch in patients with advanced-stage Parkinson disease...
  8. doi request reprint Secondary generalization in seizures of temporal lobe origin: Ictal EEG pattern in a stereo-EEG study
    Ivan Rektor
    First Department of Neurology, Masaryk University, St Anne s Hospital, Pekarska 53, Brno 656 91, Czech Republic
    Epilepsy Behav 15:235-9. 2009
    ..We tested the hypothesis that secondary generalized seizures (SGS) are not truly generalized and may involve selective regions...
  9. ncbi request reprint A SEEG study of ERP in motor and premotor cortices and in the basal ganglia
    I Rektor
    1st Department of Neurology, Masaryk University, St Anne s Hospital, Pekarska 53, 656 91 Brno, Czech Republic
    Clin Neurophysiol 114:463-71. 2003
    ..We focused our interest on the 250-600 ms time window, in which cognitive activity most probably provides the basis for the activity recorded...
  10. doi request reprint Vascular pathology in patients with idiopathic Parkinson's disease
    Ivan Rektor
    Movement Disorders Centre and Stroke Centre, First Department of Neurology, Masaryk University, St Anne s Teaching Hospital, Pekarska 53, 656 91 Brno, Czech Republic
    Parkinsonism Relat Disord 15:24-9. 2009
    ..This study provides evidence that subclinical vascular pathology could influence the clinical status by contributing to motor and cognitive dysfunction in PD...
  11. ncbi request reprint Modifications of cognitive and motor tasks affect the occurrence of event-related potentials in the human cortex
    Ivan Rektor
    First Department of Neurology, Medical Faculty of Masaryk University, St Anne s Teaching Hospital, Pekarska 53, 656 91 Brno, Czech Republic
    Eur J Neurosci 26:1371-80. 2007
    ..The study indicates a variable and task-dependent internal organization of a highly complex and widely distributed system of active cortical areas...
  12. ncbi request reprint Intracerebral ERD/ERS in voluntary movement and in cognitive visuomotor task
    I Rektor
    First Department of Neurology, Medical Faculty of Masaryk University, St Anne s Teaching Hospital, Pekarska 53, 656 91 Brno, Czech Republic
    Prog Brain Res 159:311-30. 2006
    ....
  13. ncbi request reprint Vascular parkinsonism--an update
    Ivan Rektor
    First Department of Neurology, Medical Faculty of Masaryk University, St Anne s Teaching Hospital, Pekarska 53, 65691 Brno, Czech Republic
    J Neurol Sci 248:185-91. 2006
    ..The term CVD may cover large vessel disease as well as small vessel disease. This means that territorial and lacunar infarcts and white matter lesions (WML) are all considered as CVD...
  14. ncbi request reprint How to treat tremor
    Ivan Rektor
    1st Department of Neurology, Masaryk University St Anne s Hospital, Pekarska 53, 65691, Brno, Czech Republic
    J Neurol 251:525-8. 2004
    ..Nevertheless, it is not clear whether the recommended quantity of these compounds was sufficient for a clinical effect. Most of the prescribed drugs could only have had a placebo effect...
  15. ncbi request reprint An event-related fMRI study of self-paced alphabetically ordered writing of single letters
    I Rektor
    Department of Neurology, St Anne s Hospital, Masaryk University, Pekarska 53, 65691, Brno, Czech Republic
    Exp Brain Res 173:79-85. 2006
    ..The right-sided posterior cortices may play a role in the elemental mechanisms of writing. It is possible that activation of this region is linked with the spatial dimension of the writing...
  16. ncbi request reprint Cognitive potentials in the basal ganglia-frontocortical circuits. An intracerebral recording study
    Ivan Rektor
    First Department of Neurology, Masaryk University, St Anne s Teaching Hospital, Pekarska 53, 656 91 Brno, Czech Republic
    Exp Brain Res 158:289-301. 2004
    ..Cognitive potentials were recorded from all over the putamen. The BG may play an integrative role in cognitive information processing...
  17. doi request reprint Cognitive event-related potentials and oscillations in the subthalamic nucleus
    Ivan Rektor
    First Department of Neurology, Masaryk University, St Anne s Hospital, Pekarska 53, CZ 656 91 Brno, Czech Republic
    Neurodegener Dis 7:160-2. 2010
    ..The cognitive role of the subthalamic nucleus (STN) remains largely unknown...
  18. ncbi request reprint Chorea Sancti Viti in Lexicon medicum anno 1696
    Ivan Rektor
    1st Department of Neurology, Masaryk University, St Anne Hospital, Pekarska 53, 65691 Brno, Czech Republic
    J Neurol 250:7-9. 2003
  19. doi request reprint Ictal and peri-ictal oscillations in the human basal ganglia in temporal lobe epilepsy
    Ivan Rektor
    Central European Institute of Technology CEITEC and Epilepsy Centre, First Department of Neurology, Masaryk University, St Anne s Hospital, Czech Republic
    Epilepsy Behav 20:512-7. 2011
    ..The basal ganglia did not generate epileptiform EEG activity. An inhibitory role for the basal ganglia during temporal lobe seizures is suggested...
  20. ncbi request reprint Scalp-recorded Bereitschaftspotential is the result of the activity of cortical and subcortical generators--a hypothesis
    Ivan Rektor
    First Department of Neurology, Masaryk University, St Anne s Hospital, Brno, Czech Republic
    Clin Neurophysiol 113:1998-2005. 2002
    ..This paper presents arguments in favour of the hypothesis that explains scalp-recorded BP as the result of the activity of both cortical and subcortical BP generators...
  21. ncbi request reprint Event-related potentials, CNV, readiness potential, and movement accompanying potential recorded from posterior thalamus in human subjects. A SEEG study
    I Rektor
    1st Department of Neurology, Saint Anne s Hospital, Masaryk University, Pekarska 53, 60200 Bmo, Czech Republic
    Neurophysiol Clin 31:253-61. 2001
    ..This structure may therefore be involved in both the processing of afferent information and in cognitive operations...
  22. pmc Parallel information processing in motor systems: intracerebral recordings of readiness potential and CNV in human subjects
    I Rektor
    1st Department of Neurology, Masaryk University, St Anne s Hospital, Brno, Czech Republic
    Neural Plast 7:65-72. 2000
    ..The particular regions that are simultaneously active may be determined by the task context...
  23. ncbi request reprint Intracerebral recording of readiness potential induced by a complex motor task
    I Rektor
    1st Department of Neurology, Masaryk University, St Anne Hospital, Brno, Czech Republic
    Mov Disord 16:698-704. 2001
    ..No difference between the cortical topography of RP preceding a simple motor task and the topography of RP occurring in connection with complex movement was observed...
  24. ncbi request reprint Movement-related potentials in the basal ganglia: a SEEG readiness potential study
    I Rektor
    1st Department of Neurology, Masaryk University, St Anne s Hospital, Pekarska 53, 656 91, Brno, Czech Republic
    Clin Neurophysiol 112:2146-53. 2001
    ..The brain potentials preceding and accompanying self-paced acral limb movements (Bereitschaftspotential/readiness potential (RP) paradigm) were studied in 12 patients...
  25. ncbi request reprint Interictal and ictal EEG activity in the basal ganglia: an SEEG study in patients with temporal lobe epilepsy
    Ivan Rektor
    Epilepsy Centre, 1st Department of Neurology, Masaryk University, St Anne s Hospital, Brno, Czech Republic
    Epilepsia 43:253-62. 2002
    ..The interictal and ictal EEG activity in the basal ganglia in patients with temporal lobe epilepsy were studied during invasive EEG monitoring...
  26. ncbi request reprint Basal ganglia involvement in sensory and cognitive processing. A depth electrode CNV study in human subjects
    M Bares
    1st Department of Neurology, Masaryk University, St Anne s Hospital, Pekarska 53, 656 91, Brno, Czech Republic
    Clin Neurophysiol 112:2022-30. 2001
    ..Intracranial recordings were taken from the basal ganglia (BG) in order to explore the possible role of the BG in the cognitive processing of sensory information...
  27. ncbi request reprint Cognitive performance in people with Parkinson's disease and mild or moderate depression: effects of dopamine agonists in an add-on to L-dopa therapy
    I Rektorova
    First Department of Neurology, Masaryk University, St Anne s Teaching Hospital, Brno, Czech Republic
    Eur J Neurol 12:9-15. 2005
    ..In our non-demented group of fluctuating depressed PD subjects, both PPX and PRG administration in combination with l-dopa were safe in terms of the effect on cognitive performance...
  28. ncbi request reprint Executive functions processed in the frontal and lateral temporal cortices: intracerebral study
    M Bocková
    First Department of Neurology, Masaryk University, St Anne s Hospital, 656 91, Brno, Czech Republic
    Clin Neurophysiol 118:2625-36. 2007
    ..The study was designed to investigate the neurocognitive network in the frontal and lateral temporal cortices that is activated by the complex cognitive visuomotor tasks of letter writing...
  29. doi request reprint Oscillatory changes in cognitive networks activated during a three-stimulus visual paradigm: an intracerebral study
    M Bocková
    Central European Institute of Technology, First Department of Neurology, Masaryk University, St Anne s Hospital, Brno, Czech Republic
    Clin Neurophysiol 124:283-91. 2013
    ..We focused mainly on responses after distractor stimuli in the prefrontal cortex and their possible relation to our previous results from the basal ganglia...
  30. doi request reprint The effect of cortical repetitive transcranial magnetic stimulation on cognitive event-related potentials recorded in the subthalamic nucleus
    M Balaz
    Department of Neurology, St Anne s University Hospital, Medical School of Masaryk University, Pekarska 53, 656 91, Brno, Czech Republic
    Exp Brain Res 203:317-27. 2010
    ..Connections (the IFC-STN hyperdirect pathway) with the cortex that bypass the BG-thalamocortical circuitries could explain the position of the STN in the processing of executive functions...
  31. doi request reprint The level of frontal-temporal beta-2 band EEG synchronization distinguishes anterior cingulate cortex from other frontal regions
    M Kukleta
    Department of Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic
    Conscious Cogn 19:879-86. 2010
    ..These findings indicate a particular role of the ACC in large-scale communication, which could reflect its unique integrative functions in cognitive processing...
  32. ncbi request reprint Cognitive network interactions and beta 2 coherence in processing non-target stimuli in visual oddball task
    M Kukleta
    Department of Physiology, Brno, Czech Republic
    Physiol Res 58:139-48. 2009
    ....
  33. ncbi request reprint Effect of vagal nerve stimulation on auditory and visual event-related potentials
    M Brazdil
    Department of Neurology, Epilepsy Center Brno, Masaryk University, St Anne s Hospital, Brno, Czech Republic
    Eur J Neurol 8:457-61. 2001
    ..This observation supports the theory of a possible positive effect of low-intensity VNS on the cognitive functions...
  34. ncbi request reprint Cognitive functioning after repetitive transcranial magnetic stimulation in patients with cerebrovascular disease without dementia: a pilot study of seven patients
    I Rektorova
    First Department of Neurology, Masaryk University, Teaching Hospital sv Anna, Pekarska 53, 656 91, Brno, Czech Republic
    J Neurol Sci 229:157-61. 2005
    ....
  35. doi request reprint Involvement of the subthalamic nucleus and globus pallidus internus in attention
    M Bocková
    First Department of Neurology, Medical Faculty, St Anne s Teaching Hospital, Masaryk University, Pekarska 53, 656 91, Brno, Czech Republic
    J Neural Transm 118:1235-45. 2011
    ..This positivity probably reflects an attentional orienting response to the distractor stimuli. The STN and GPi are probably involved in attentional cerebral networks...
  36. ncbi request reprint Beta 2-band synchronization during a visual oddball task
    M Kukleta
    Department of Physiology, Masaryk University, Komenskeho 2, 662 43 Brno, Czech Republic
    Physiol Res 58:725-32. 2009
    ....
  37. ncbi request reprint Ictal limb dystonia in temporal lobe epilepsy. an invasive video-EEG finding
    R Kuba
    Epilepsy Centre, First Department of Neurology, St Anne s University Hospital, Brno, Czech Republic
    Eur J Neurol 10:641-9. 2003
    ..The putamen probably collaborates in the genesis of ID, but it does not generate the epileptic discharge during its course...
  38. ncbi request reprint Intracerebral event-related potentials to subthreshold target stimuli
    M Brazdil
    First Department of Neurology, Masaryk University, St Anne s Hospital, Pekarska 53, 656 91 Brno, Czech Republic
    Clin Neurophysiol 112:650-61. 2001
    ..Event-related potentials (ERPs) elicited by subthreshold visual stimuli were recorded directly from human frontal and temporal lobe structures to study unconscious perception...
  39. ncbi request reprint Directional functional coupling of cerebral rhythms between anterior cingulate and dorsolateral prefrontal areas during rare stimuli: a directed transfer function analysis of human depth EEG signal
    Milan Brazdil
    First Department of Neurology, Masaryk University, St Anne s Hospital, Brno, Czech Republic
    Hum Brain Mapp 30:138-46. 2009
    ..01). These results provide support to the hypothesis that ACC directly or indirectly affects the oscillatory activity of dorsolateral PFC by a selective frequency code under typical oddball conditions...
  40. ncbi request reprint Late divergence of target and nontarget ERPs in a visual oddball task
    A Damborská
    Department of Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic
    Physiol Res 61:307-18. 2012
    ..Finding of late divergence indicates that functional differences exist even not sooner than during the final phase of the task...
  41. doi request reprint Long-term levetiracetam treatment in patients with epilepsy: 3-year follow up
    R Kuba
    Brno Epilepsy Centre, First Department of Neurology, St Anne s Teaching Hospital, Faculty of Medicine, Masaryk University, Brno, Czech Republic
    Acta Neurol Scand 121:83-8. 2010
    ..To assess the long-term efficacy and tolerability of levetiracetam in routine clinical practice...
  42. ncbi request reprint Cortical and subcortical distribution of middle and long latency auditory and visual evoked potentials in a cognitive (CNV) paradigm
    Martin Bares
    First Department of Neurology, Masaryk University, St Anne s Hospital, Pekarska 53, 656 91 Brno, Czech Republic
    Clin Neurophysiol 114:2447-60. 2003
    ..The focus of the study was on the time and space distribution of middle and late post-stimulus evoked potential (EP) components, and on the processing of sensory information in the subcortical-cortical networks...
  43. doi request reprint The posterior medial cortex is involved in visual but not in verbal memory encoding processing: an intracerebral recording study
    K Stillová
    Central European Institute of Technology CEITEC, First Department of Neurology, St Anne s Teaching Hospital, Masaryk University, Pekarska 53, 656 91, Brno, Czech Republic
    J Neural Transm 120:391-7. 2013
    ..The PMC appears to be involved not only in higher-order top-down cognitive activities but also in more basic, rather than bottom-up activities...
  44. ncbi request reprint Intracortical inhibition and facilitation are impaired in patients with early Parkinson's disease: a paired TMS study
    M Bares
    First Department of Neurology and the Movement Disorders Centre, Masaryk University, St Anne s Hospital, Brno, Czech Republic
    Eur J Neurol 10:385-9. 2003
    ..In conclusion, it can be supposed that both intracortical inhibition and facilitation are impaired in patients with early PD using other antiparkinsonian treatments than L-DOPA or dopamine agonists...
  45. ncbi request reprint Reorganization of language-related neuronal networks in patients with left temporal lobe epilepsy - an fMRI study
    M Brazdil
    Department of Neurology, Brno Epilepsy Centre, St Anne s University Hospital, Brno, Czech Republic
    Eur J Neurol 12:268-75. 2005
    ..Our results support the hypothesis of a significant intra- and interhemispheric functional reorganization of language-related neuronal networks in left TLE...
  46. ncbi request reprint Effect of subthreshold target stimuli on event-related potentials
    M Brazdil
    Department of Neurology, Masaryk University, St Anna Hospital, Pekarska, Czech Republic
    Electroencephalogr Clin Neurophysiol 107:64-8. 1998
    ..Event-related potentials (ERPs) elicited by subthreshold visual stimuli were studied to assess the relationship between unconscious cognitive processing and the electrical activity of the brain...
  47. doi request reprint Effect of high frequency repetitive transcranial magnetic stimulation on reaction time, clinical features and cognitive functions in patients with Parkinson's disease
    Silvie Sedlackova
    First Department of Neurology, St Anne s Teaching Hospital, Masaryk University, Brno, Czech Republic
    J Neural Transm 116:1093-101. 2009
    ..rTMS applied over all three stimulated areas was well tolerated and safe in terms of the cognitive and motor effects...
  48. doi request reprint Long-term vagus nerve stimulation in children with focal epilepsy
    M Ryzí
    Department of Child Neurology, Epilepsy Center Brno, Faculty of Medicine, Brno University Hospital, Masaryk University, Czech Republic
    Acta Neurol Scand 127:316-22. 2013
    ..The aim of the study was to evaluate the long-term efficacy and hospitalization rates in children with refractory focal epilepsy treated by vagus nerve stimulation...
  49. ncbi request reprint Long-term levetiracetam treatment of epilepsy patients: clinical audit
    R Kuba
    Epilepsy Centre Department of Neurology, Masaryk University, St Anne s Teaching Hospital, Brno, Czech Republic
    Epilepsy Res 72:111-9. 2006
    ..One hundred and ninety-nine patients were treated for at least 6 months. We evaluated LEV efficacy for all types of seizures together, and for simple partial, complex partial and secondary generalized seizures individually...
  50. ncbi request reprint Amantadine infusion in treatment of motor fluctuations and dyskinesias in Parkinson's disease
    E Ruzicka
    Movement Disorder Center, Department of Neurology, 1st Medical Faculty, Charles University and General Teaching Hospital, Prague, Czech Republic
    J Neural Transm 107:1297-306. 2000
    ..In advantage to simple oral therapy, AMS infusions allowed fast introduction of a profound and durable treatment effect...
  51. ncbi request reprint Pramipexole and pergolide in the treatment of depression in Parkinson's disease: a national multicentre prospective randomized study
    I Rektorova
    First Department of Neurology, Masaryk University, St Anne s Teaching Hospital, Brno, Czech Republic
    Eur J Neurol 10:399-406. 2003
    ..Our results demonstrate the antidepressant effect of PPX in patients with PD while we can't make any conclusions with regard to antidepressant effect of PRG...
  52. doi request reprint Peri-ictal bed leaving in temporal lobe epilepsy: incidence and lateralizing value
    K Musilova
    Behavioral and Social Neuroscience Reasearch Group, Central European Institute of Technology, Masaryk University, Brno, Czech Republic
    Epilepsy Behav 21:143-6. 2011
    ..PBL is a relatively frequent peri-ictal sign in patients with TLE. The side of PBL in patients with TLE-HS lateralizes the seizure onset to the ipsilateral temporal lobe...
  53. ncbi request reprint Participation of the subthalamic nucleus in executive functions: An intracerebral recording study
    Marek Balaz
    Department of Neurology, Movement Disorders Centre, St Anne s University Hospital, Medical School of Masaryk University, Pekarska 53, Brno, Czech Republic
    Mov Disord 23:553-7. 2008
    ..This could suggest that the STN takes part in the executive function processing...
  54. ncbi request reprint fMRI evaluation of hemispheric language dominance using various methods of laterality index calculation
    Pavel Chlebus
    Department of Neurology, Masaryk University, St Anne s University Hospital, Pekarska 53, Brno, 65691, Czech Republic
    Exp Brain Res 179:365-74. 2007
    ..94, P = 1 x 10(-7)). However, the new LI calculation methods used in the present study did not produce a statistically significant benefit in comparison to previously reported methods...
  55. doi request reprint Occurrence and lateralizing value of "rare" peri-ictal vegetative symptoms in temporal lobe epilepsy
    K Musilova
    Epilepsy Centre Brno, First Department of Neurology, St Anne s University Hospital and Faculty of Medicine, Masaryk University, Brno, Czech Republic
    Epilepsy Behav 19:372-5. 2010
    ..In patients with TLE, pC and pWD were quite frequent; we observed pV and pS less frequently. Both pC and pWD have a significant lateralizing value in TLE...
  56. doi request reprint Serum inflammatory biomarkers in Parkinson's disease
    M Dufek
    1st Department of Neurology, Masaryk University, St Anne s University Hospital, Pekarska 53, 65691 Brno, Czech Republic
    Parkinsonism Relat Disord 15:318-20. 2009
    ..Our results indicate that the inflammatory process may be reflected in the serum; nevertheless, further research is needed to elucidate the possible clinical implications...
  57. doi request reprint Functional neuroanatomy of vocalization in patients with Parkinson's disease
    I Rektorova
    Applied Neurosciences Research Group, Central European Institute of Technology, CEITEC, Masaryk University, Brno, Czech Republic
    J Neurol Sci 313:7-12. 2012
    ..In Parkinson's disease (PD) both speech production and self-monitoring of voiced speech are altered...
  58. ncbi request reprint Event-related desynchronization/synchronization in the putamen. An SEEG case study
    D Sochurkova
    First Department of Neurology, St Anne s Hospital, Masaryk University, Brno, Czech Republic
    Exp Brain Res 149:401-4. 2003
    ..This is the first report of ERD/ERS in the basal ganglia...
  59. ncbi request reprint Intracerebral recording of cortical activity related to self-paced voluntary movements: a Bereitschaftspotential and event-related desynchronization/synchronization. SEEG study
    Daniela Sochurkova
    1st Department of Neurology, St Anne s Hospital, Masaryk University, Pekarska 53, Brno, Czech Republic
    Exp Brain Res 173:637-49. 2006
    ....
  60. ncbi request reprint Functional abnormalities in the primary orofacial sensorimotor cortex during speech in Parkinson's disease
    Irena Rektorova
    1st Department of Neurology, Masaryk University, St Anne s Hospital, Brno, Czech Republic
    Mov Disord 22:2043-51. 2007
    ..These results might reflect compensatory mechanisms and/or treatment effects that take place in mild to moderately ill PD patients with quality of speech yet comparable with that of age-matched controls...
  61. ncbi request reprint Disturbed intracortical excitability in early Parkinson's disease is l-DOPA dose related: a prospective 12-month paired TMS study
    Martin Bares
    First Department of Neurology and the Movement Disorders Centre, Medical Faculty Masaryk University, St Anne s Hospital, Pekarska 53, 656 91 Brno, Czech Republic
    Parkinsonism Relat Disord 13:489-94. 2007
    ..The level of disturbed intracortical excitability strongly correlated with the total daily dose of l-DOPA. The level of cortical excitability in PD patients seems to be indirectly related to the nigro-striatal functioning...
  62. ncbi request reprint Lateralized ictal immobility of the upper limb in patients with temporal lobe epilepsy
    R Kuba
    Epilepsy Centre, First Department of Neurology, St Anne s University Hospital, Brno, Czech Republic
    Eur J Neurol 12:886-90. 2005
    ..LIL has an excellent lateralizing value for the contralateral hemisphere. It is a negative motor sign, and its genesis is probably associated with the epileptic involvement of the contralateral frontal lobe...
  63. ncbi request reprint The selective gating of the N30 cortical component of the somatosensory evoked potentials of median nerve is different in the mesial and dorsolateral frontal cortex: evidence from intracerebral recordings
    Petr Kanovsky
    First Department of Neurology, Masaryk University, St Anne Hospital, Pekarska 53, 656 91, Brno, Czech Republic
    Clin Neurophysiol 114:981-91. 2003
    ..The somatosensory evoked potentials of the median nerve (SEP) were registered intracerebrally in 12 subjects to elucidate the origin of N30 component and its behavior in the motor 'gating' tasks...
  64. doi request reprint Interictal high-frequency oscillations indicate seizure onset zone in patients with focal cortical dysplasia
    Milan Brazdil
    Brno Epilepsy Center, Departments of Neurology and Neurosurgery, St Anne s University Hospital and Medical Faculty of Masaryk University, Brno, Czech Republic
    Epilepsy Res 90:28-32. 2010
    ..Our study demonstrates a capacity of interictal HFO to detect the SOZ in focal cortical dysplasias...
  65. ncbi request reprint Abnormalities of cortical excitability and cortical inhibition in cervical dystonia Evidence from somatosensory evoked potentials and paired transcranial magnetic stimulation recordings
    Petr Kanovsky
    1st Department of Neurology, Masaryk University, St Anne Hospital, Pekarska 53, 656 91 Brno, Czech Republic
    J Neurol 250:42-50. 2003
    ..e. it is located within the hemisphere contralateral to the direction of head deviation...
  66. doi request reprint Lateralized ictal dystonia of upper and lower limbs in patients with temporal lobe epilepsy
    Robert Kuba
    Brno Epilepsy Centre, First Department of Neurology, St Anne s University Hospital and Faculty of Medicine, Masaryk University, Brno, Czech Republic
    Epileptic Disord 12:109-15. 2010
    ..To perform a retrospective study to determine the incidence and lateralizing value of ictal dystonia in patients with temporal lobe epilepsy...
  67. ncbi request reprint Error processing--evidence from intracerebral ERP recordings
    Milan Brazdil
    First Department of Neurology, Masaryk University, 65691 Brno, Czech Republic
    Exp Brain Res 146:460-6. 2002
    ..Thirdly, the latency differences of the Ne across lobes suggest that the Ne is primarily elicited in posterior and temporal, and only later in frontal regions...
  68. ncbi request reprint Levodopa-induced dyskinesias and continuous subcutaneous infusions of apomorphine: results of a two-year, prospective follow-up
    Petr Kanovsky
    1st Department of Neurology, Masaryk University, St Anne Hospital, Brno, Czech Republic
    Mov Disord 17:188-91. 2002
    ..Twelve patients with levodopa-induced dyskinesias were treated with continuous subcutaneous apomorphine. A markedly significant reduction in peak dose dyskinesias occurred over a two-year follow-up...
  69. doi request reprint Correlation study of optimized voxel-based morphometry and (1)H MRS in patients with mesial temporal lobe epilepsy and hippocampal sclerosis
    Milan Brazdil
    Department of Neurology, Brno Epilepsy Centre, St Anne s Hospital, Masaryk University Brno, Czech Republic
    Hum Brain Mapp 30:1226-35. 2009
    ..To assess whether structural and metabolic brain abnormalities are correlated in MTLE/HS syndrome...
  70. doi request reprint Neural correlates of affective picture processing--a depth ERP study
    Milan Brazdil
    Department of Neurology, St Anne s University Hospital, and Faculty of Medicine, Masaryk University, Brno, Czech Republic
    Neuroimage 47:376-83. 2009
    ..These results are in agreement with a multisystem model of human emotion, distributed far beyond the typical limbic system and substantially comprising lateral aspects of both frontal lobes as well...
  71. ncbi request reprint Combined event-related fMRI and intracerebral ERP study of an auditory oddball task
    Milan Brazdil
    First Department of Neurology, St Anne s University Hospital, Brno, Czech Republic
    Neuroimage 26:285-93. 2005
    ..Both methods should thus be viewed as mutually complementary in investigations of the spatial distribution of cortical and subcortical activation during oddball task...
  72. ncbi request reprint Dropped head syndrome in severe intractable epilepsies with mental retardation
    Milan Brazdil
    Brno Epilepsy Center, First Department of Neurology, St Anne s University Hospital, 65691 Brno, Czech Republic
    Seizure 14:282-7. 2005
    ..The syndrome has a relatively benign clinical course. To date, there have been no reports of dropped head syndrome in epileptic patients...
  73. ncbi request reprint Combining advanced neuroimaging techniques in presurgical workup of non-lesional intractable epilepsy
    Milan Brazdil
    Department of Neurology, Brno Epilepsy Center, Czech Republic
    Epileptic Disord 8:190-4. 2006
    ..The rationale for this case report is to assess the degree of congruency between the results of several advanced functional, metabolic, and structural neuroimaging techniques used in patients with MRI-negative focal epilepsy...
  74. ncbi request reprint The impact of motor activity on intracerebral ERPs: P3 latency variability in modified auditory odd-ball paradigms involving a motor task
    Petr Kanovsky
    1st Department of Neurology, St Anne Hospital, Masaryk University, Pekarska 53, 656 91 Brno, Czech Republic
    Neurophysiol Clin 33:159-68. 2003
    ..The finding of reduction and subsequent prolongation of P3 latency in the mesial frontal cortex might reflect the unique specialization of this area and its specific involvement in motor processing...
  75. ncbi request reprint Intracerebral P3-like waveforms and the length of the stimulus-response interval in a visual oddball paradigm
    Robert Roman
    Department of Physiology, Medical Faculty, Masaryk University, Komenského nám 2 662 43 Brno, Czech Republic
    Clin Neurophysiol 116:160-71. 2005
    ..This study investigated the possible linkage of intracerebrally recorded P3-like waveforms to the processes induced by stimulus perception or motor response formation...
  76. ncbi request reprint Effective connectivity in target stimulus processing: a dynamic causal modeling study of visual oddball task
    Milan Brazdil
    1st Department of Neurology, St Anne s University Hospital, Brno, Czech Republic
    Neuroimage 35:827-35. 2007
    ..To investigate the fundamental connectivity architecture of neural structures involved in the goal-directed processing of target events...
  77. ncbi request reprint Atypical hemispheric language dominance in left temporal lobe epilepsy as a result of the reorganization of language functions
    Milan Brazdil
    Brno Epilepsy Center, Department of Neurology, St Anne s University Hospital, Brno 656 91, Czech Republic
    Epilepsy Behav 4:414-9. 2003
    ..Our results strongly support the influential impact of epileptiform activity spreading from the left temporal lobe structures on the reorganization of language functions in patients with early brain injury...
  78. ncbi request reprint Intracerebral somatosensory event-related potentials: effect of response type (button pressing versus mental counting) on P3-like potentials within the human brain
    Milan Brazdil
    1st Department of Neurology, St Anne s University Hospital, Pekarska, Brno 656 91, Czech Republic
    Clin Neurophysiol 114:1489-96. 2003
    ..To assess the contribution of different anatomical brain sites to the genesis of P3 phenomena with respect to button pressing versus mental counting tasks...
  79. doi request reprint Epilepsia, epileptiform abnormalities, non-right-handedness, hypotonia and severe decreased IQ are associated with language impairment in autism
    Hana Oslejskova
    Department of Pediatric Neurology, Brno Epilepsy Centre, Children s Medical Center, University Hospital, Brno, Czech Republic
    Epileptic Disord 9:S9-18. 2007
    ....
  80. ncbi request reprint Effect of vagal nerve stimulation on patients with bitemporal epilepsy
    R Kuba
    Department of Neurology, Brno Epilepsy Center, Masaryk University, St Anne s Hospital, Brno, Czech Republic
    Eur J Neurol 10:91-4. 2003
    ..5%). These data demonstrate the positive and long-lasting effect of VNS on seizure reduction in patients with intractable bitemporal epilepsy. The main mechanism of this chronic effect is not fully understood...
  81. ncbi request reprint The effect of apomorphine administration on smooth pursuit ocular movements in early Parkinsonian patients
    Martin Bares
    1st Department of Neurology, Masaryk University, St Anne Hospital, Pekarska 53, 656 91, Brno, Czech Republic
    Parkinsonism Relat Disord 9:139-44. 2003
    ..Significant differences in SPEM were found between both groups, as well as in the SPEM before and after ASA. The theory that SPEM is disturbed in early PD patients was confirmed. The dopaminergic control of horizontal SPEM is supposed...
  82. ncbi request reprint Magnetic resonance spectroscopy of the thalamus in patients with typical absence epilepsy
    Dagmar Fojtíková
    Brno Epilepsy Centre, Department of Neurology, Masaryk University, St Anne s University Hospital, Pekarska 53, 656 91 Brno, Czech Republic
    Seizure 15:533-40. 2006
    ..Special attention was paid to levels of N-acetylaspartate (NAA) and creatine (Cr), and to the NAA/Cr ratio...
  83. ncbi request reprint The long-lasting improvement of sexual dysfunction in patients with advanced, fluctuating Parkinson's disease induced by pergolide: evidence from the results of an open, prospective, one-year trial
    Michal Pohanka
    Department of Sexology, St Anne Hospital, Brno, Czech Republic
    Parkinsonism Relat Disord 11:509-12. 2005
    ..Nevertheless, the relationship between pergolide treatment and incidence of restrictive valvular heart disease must be considered...
  84. ncbi request reprint Effect of vagal nerve stimulation on interictal epileptiform discharges: a scalp EEG study
    Robert Kuba
    Department of Neurology, Brno Epilepsy Centre, Masaryk University, St Anne s Hospital, Brno, Czech Republic
    Epilepsia 43:1181-8. 2002
    ..To investigate the effects of acute vagal nerve stimulation (VNS) on interictal epileptiform discharges (IEDs)...
  85. ncbi request reprint Excessive daytime sleepiness and 'sleep attacks' induced by entacapone
    Martin Bares
    1st Department of Neurology and Movement Disorders Centre, St Anne Hospital, Masaryk University, Brno, Czech Republic
    Fundam Clin Pharmacol 17:113-6. 2003
    ..This is another demonstration that inappropriate daytime sleep episodes are not exclusive to dopamine agonists...
  86. doi request reprint Effect of chronic vagal nerve stimulation on interictal epileptiform discharges
    Robert Kuba
    Epilepsy Center Brno, First Department of Neurology, St Anne s University Hospital and Faculty of Medicine, Masaryk University, 65691 Brno, Pekarska 53, Czech Republic
    Seizure 19:352-5. 2010
    ..No other significant correlations were found. VNS reduced IEDs in patients chronically simulated for epilepsy. The reduction of IEDs was greater in patients who responded to VNS and in patients suffering from temporal lobe epilepsy...
  87. ncbi request reprint The trend in public attitudes in the Czech Republic towards persons with epilepsy
    I Novotna
    First Department of Neurology, Masaryk University, St Anne s Hospital, Brno, Czech Republic
    Eur J Neurol 9:535-40. 2002
    ..However, the answers concerning the willingness to help a person having a seizure show that, despite certain progress, the quality of information that the Czech population has is not fully satisfactory...
  88. doi request reprint Sexual functions in women with focal epilepsy. A preliminary study
    Věra Zelená
    Department of Neurology, Masaryk University, St Anne s Hospital, Brno, Czech Republic
    Epileptic Disord 9:S83-92. 2007
    ..Sexual dysfunctions are relatively common problems in epileptic women with focal epilepsy. Prospective studies, including a control group, are needed...
  89. ncbi request reprint Unruptured intracranial aneurysm as a cause of focal epilepsy: an excellent postoperative outcome after intra-arterial treatment
    Robert Kuba
    Department of Neurology, Brno Epilepsy Centre, Masaryk University, St Anneís Hospital, Brno, Czech Republic
    Epileptic Disord 6:41-4. 2004
    ..This is the first case report that presents the successful treatment of UIA-related epilepsy by means of intravascular embolisation...
  90. ncbi request reprint Recurrent miller fisher syndrome with abnormal terminal axon dysfunction: a case report
    Jan Tomcík
    1st Department of Neurology, St Anne s University Hospital, Medical Faculty Masaryk University Brno, Czech Republic
    Acta Neurol Belg 107:112-4. 2007
    ....
  91. ncbi request reprint Sexual dysfunctions and blood hormonal profile in men with focal epilepsy
    Robert Kuba
    Department of Neurology, Masaryk University, St Anne s Hospital, Brno, Czech Republic
    Epilepsia 47:2135-40. 2006
    ..To evaluate the incidence of sexual dysfunction in men with focal epilepsy and to establish their hormonal profiles...
  92. doi request reprint Vagus nerve stimulation: longitudinal follow-up of patients treated for 5 years
    Robert Kuba
    Brno Epilepsy Center First Department of Neurology, St Anne s University Hospital and Faculty of Medicine, Masaryk University, Brno, Pekarska 53, Czech Republic
    Seizure 18:269-74. 2009
    ..Complications and chronic adverse effects occurred in 13.3% of patients. VNS is an effective and safe method to refractory epilepsy in common clinical practice...
  93. ncbi request reprint Synchronization of gamma oscillations increases functional connectivity of human hippocampus and inferior-middle temporal cortex during repetitive visuomotor events
    Claudio Babiloni
    Dipartimento di Fisiologia Umana e Farmacologia, Universita degli Studi di Roma La Sapienza, Piazzale Aldo Moro 5, 00185 Rome, Italy
    Eur J Neurosci 19:3088-98. 2004
    ..These results suggest that recency processes do modulate the magnitude and functional coupling of brain rhythmicity (especially gamma) in the human temporal cortex...
  94. ncbi request reprint Functional coupling between anterior prefrontal cortex (BA10) and hand muscle contraction during intentional and imitative motor acts
    Claudio Babiloni
    Dipartimento di Fisiologia Umana e Farmacologia, Universita La Sapienza, Rome, Italy
    Neuroimage 39:1314-23. 2008
    ..The present results suggest that anterior prefrontal cortex (BA10) might control subjects' behavior by means of functional cortico-muscular coupling at selective frequency bands (theta and wide gamma rhythms)...
  95. ncbi request reprint Repetitive transcranial stimulation for freezing of gait in Parkinson's disease
    Irena Rektorova
    Mov Disord 22:1518-9. 2007
  96. ncbi request reprint Rotigotine transdermal patch enables rapid titration to effective doses in advanced-stage idiopathic Parkinson disease: subanalysis of a parallel group, open-label, dose-escalation study
    Tomislav Babic
    CNS International, I3 Research, Maidenhead, Berks, SL6 8AD, United Kingdom
    Clin Neuropharmacol 29:238-42. 2006
    ..The aim of this analysis was to determine the safety of a more rapid titration of rotigotine by assessing the tolerability of escalating transdermal doses of rotigotine given in 2 different titration schemes...
  97. doi request reprint Intravenous immunoglobulin in relapsing-remitting multiple sclerosis: a dose-finding trial
    F Fazekas
    Department of Neurology, Medical University of Graz, Auenbruggerplatz 22, A 8036 Graz, Austria
    Neurology 71:265-71. 2008
    ..We therefore set out to test two different doses of a new formulation of immunoglobulin termed IGIV-C 10% for suppression of both clinical and MRI disease activity as well as safety...
  98. ncbi request reprint Penile erections and hypersexuality induced by pergolide treatment in advanced, fluctuating Parkinson's disease
    Petr Kanovsky
    J Neurol 249:112-4. 2002