Jan Laczó

Summary

Country: Czech Republic

Publications

  1. doi request reprint Spatial navigation testing discriminates two types of amnestic mild cognitive impairment
    Jan Laczó
    Memory Disorders Clinic, Department of Neurology, 2nd Medical School, Charles University in Prague, Prague, Czech Republic
    Behav Brain Res 202:252-9. 2009
  2. doi request reprint Spatial navigation and APOE in amnestic mild cognitive impairment
    Jan Laczó
    Memory Disorders Unit, Department of Neurology, 2nd Medical School, Charles University in Prague, Prague, Czech Republic
    Neurodegener Dis 8:169-77. 2011
  3. pmc Spatial navigation deficit in amnestic mild cognitive impairment
    Jakub Hort
    Memory Disorders Clinic, Department of Neurology, Second Medical School, Charles University, 150 18 Prague 5, Czech Republic
    Proc Natl Acad Sci U S A 104:4042-7. 2007
  4. doi request reprint Recognition of facial emotional expression in amnestic mild cognitive impairment
    Alexandra Varjassyová
    Memory Disorders Clinic, Department of Neurology, Charles University in Prague, 2nd Faculty of Medicine and University Hospital Motol, Prague, Czech Republic
    J Alzheimers Dis 33:273-80. 2013
  5. ncbi request reprint Diffusion tensor imaging in Alzheimer disease and mild cognitive impairment
    Irena Stěpán-Buksakowska
    Department of Radiology, Charles University, 2nd Medical Faculty and University Hospital Motol Prague, Czech Republic, V Uvalu 84, 150 06, Prague, Czech Republic
    Neurol Neurochir Pol 46:462-71. 2012
  6. doi request reprint Risk factors for spatial memory impairment in patients with temporal lobe epilepsy
    Jana Amlerová
    Department of Neurology, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol, Prague, Czech Republic
    Epilepsy Behav 26:57-60. 2013
  7. pmc Spatial navigation impairment is proportional to right hippocampal volume
    Zuzana Nedelska
    Memory Disorders Clinic, Department of Neurology, Charles University in Prague, 2 Faculty of Medicine and Motol University Hospital, 150 06 Prague 5, Czech Republic
    Proc Natl Acad Sci U S A 109:2590-4. 2012
  8. doi request reprint Disturbance of real space navigation in moderately advanced but not in early Huntington's disease
    Veronika Majerová
    Department of Neurology and Center of Clinical Neuroscience, Charles University in Prague, 1st Faculty of Medicine and General University Hospital in Prague, Katerinska 30, 12800 Praha 2, Czech Republic
    J Neurol Sci 312:86-91. 2012
  9. pmc Spatial navigation-a unique window into physiological and pathological aging
    Ivana Gazova
    Department of Neurology, Memory Disorders Clinic, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol Prague 5, Czech Republic
    Front Aging Neurosci 4:16. 2012

Collaborators

  • Jakub Hort
  • Ross Andel
  • Daniel Horinek
  • Yonas E Geda
  • Evzen Ruzicka
  • Jana Amlerová
  • Kamil Vlcek
  • Katerina Sheardová
  • Zuzana Nedelska
  • Alexandra Varjassyová
  • Martin Vyhnálek
  • Ivana Gazova
  • Jiri Lisy
  • Veronika Majerová
  • Irena Stěpán-Buksakowska
  • Hana Magerová
  • Ondrej Bradác
  • Iva Holmerová
  • Petr Marusic
  • Alena Javurkova
  • Martin Bojar
  • Ivana Mokrisova
  • Eva Hyncicova
  • Jan Bures
  • Miloslav Rocek
  • Frantisek Charvát
  • Aaron Rulseh
  • Tomas Kalincik
  • Jiri Keller
  • Jan Roth

Detail Information

Publications10

  1. doi request reprint Spatial navigation testing discriminates two types of amnestic mild cognitive impairment
    Jan Laczó
    Memory Disorders Clinic, Department of Neurology, 2nd Medical School, Charles University in Prague, Prague, Czech Republic
    Behav Brain Res 202:252-9. 2009
    ..Finally, the HaMCI group performed almost identically as the AD group. Spatial navigation deficit is particularly pronounced in individuals with hippocampus-related memory impairment and may signal preclinical AD...
  2. doi request reprint Spatial navigation and APOE in amnestic mild cognitive impairment
    Jan Laczó
    Memory Disorders Unit, Department of Neurology, 2nd Medical School, Charles University in Prague, Prague, Czech Republic
    Neurodegener Dis 8:169-77. 2011
    ..The effect of APOE ε4 allele (ε4) on spatial navigation in amnestic mild cognitive impairment (aMCI) is unknown...
  3. pmc Spatial navigation deficit in amnestic mild cognitive impairment
    Jakub Hort
    Memory Disorders Clinic, Department of Neurology, Second Medical School, Charles University, 150 18 Prague 5, Czech Republic
    Proc Natl Acad Sci U S A 104:4042-7. 2007
    ..Our results suggest that spatial navigation impairment occurs early in the development of AD and can be used for monitoring of the disease progression or for evaluation of presymptomiatic AD...
  4. doi request reprint Recognition of facial emotional expression in amnestic mild cognitive impairment
    Alexandra Varjassyová
    Memory Disorders Clinic, Department of Neurology, Charles University in Prague, 2nd Faculty of Medicine and University Hospital Motol, Prague, Czech Republic
    J Alzheimers Dis 33:273-80. 2013
    ..13; 95% CI, 0.36-3.57; p = 0.836). Therefore, FER, but not FFI, may be impaired in MD-aMCI. This implies that in MD-aMCI, the tasks of FER and FFI may involve segregated neurocognitive networks...
  5. ncbi request reprint Diffusion tensor imaging in Alzheimer disease and mild cognitive impairment
    Irena Stěpán-Buksakowska
    Department of Radiology, Charles University, 2nd Medical Faculty and University Hospital Motol Prague, Czech Republic, V Uvalu 84, 150 06, Prague, Czech Republic
    Neurol Neurochir Pol 46:462-71. 2012
    ....
  6. doi request reprint Risk factors for spatial memory impairment in patients with temporal lobe epilepsy
    Jana Amlerová
    Department of Neurology, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol, Prague, Czech Republic
    Epilepsy Behav 26:57-60. 2013
    ..The results indicate that not only temporal lobe dysfunction itself but also low general cognitive abilities may contribute to the navigation impairment...
  7. pmc Spatial navigation impairment is proportional to right hippocampal volume
    Zuzana Nedelska
    Memory Disorders Clinic, Department of Neurology, Charles University in Prague, 2 Faculty of Medicine and Motol University Hospital, 150 06 Prague 5, Czech Republic
    Proc Natl Acad Sci U S A 109:2590-4. 2012
    ..The respective real-space and virtual scores strongly correlated with each other. Our findings indicate that the right hippocampus plays a critical role in allocentric navigation, particularly when cognitive impairment is present...
  8. doi request reprint Disturbance of real space navigation in moderately advanced but not in early Huntington's disease
    Veronika Majerová
    Department of Neurology and Center of Clinical Neuroscience, Charles University in Prague, 1st Faculty of Medicine and General University Hospital in Prague, Katerinska 30, 12800 Praha 2, Czech Republic
    J Neurol Sci 312:86-91. 2012
    ..Several studies have associated the allocentric navigation with the hippocampus and the egocentric navigation with the striatum. The striatum is predominantly impaired from the early stages of Huntington's disease...
  9. pmc Spatial navigation-a unique window into physiological and pathological aging
    Ivana Gazova
    Department of Neurology, Memory Disorders Clinic, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol Prague 5, Czech Republic
    Front Aging Neurosci 4:16. 2012
    ....