Country: Czech Republic
- Spatial navigation testing discriminates two types of amnestic mild cognitive impairmentJan Laczó
Memory Disorders Clinic, Department of Neurology, 2nd Medical School, Charles University in Prague, Prague, Czech Republic
Behav Brain Res 202:252-9. 2009..Finally, the HaMCI group performed almost identically as the AD group. Spatial navigation deficit is particularly pronounced in individuals with hippocampus-related memory impairment and may signal preclinical AD...
- Spatial navigation and APOE in amnestic mild cognitive impairmentJan Laczó
Memory Disorders Unit, Department of Neurology, 2nd Medical School, Charles University in Prague, Prague, Czech Republic
Neurodegener Dis 8:169-77. 2011..The effect of APOE ε4 allele (ε4) on spatial navigation in amnestic mild cognitive impairment (aMCI) is unknown...
- Spatial navigation deficit in amnestic mild cognitive impairmentJakub Hort
Memory Disorders Clinic, Department of Neurology, Second Medical School, Charles University, 150 18 Prague 5, Czech Republic
Proc Natl Acad Sci U S A 104:4042-7. 2007..Our results suggest that spatial navigation impairment occurs early in the development of AD and can be used for monitoring of the disease progression or for evaluation of presymptomiatic AD...
- Recognition of facial emotional expression in amnestic mild cognitive impairmentAlexandra Varjassyová
Memory Disorders Clinic, Department of Neurology, Charles University in Prague, 2nd Faculty of Medicine and University Hospital Motol, Prague, Czech Republic
J Alzheimers Dis 33:273-80. 2013..13; 95% CI, 0.36-3.57; p = 0.836). Therefore, FER, but not FFI, may be impaired in MD-aMCI. This implies that in MD-aMCI, the tasks of FER and FFI may involve segregated neurocognitive networks...
- Diffusion tensor imaging in Alzheimer disease and mild cognitive impairmentIrena Stěpán-Buksakowska
Department of Radiology, Charles University, 2nd Medical Faculty and University Hospital Motol Prague, Czech Republic, V Uvalu 84, 150 06, Prague, Czech Republic
Neurol Neurochir Pol 46:462-71. 2012....
- Risk factors for spatial memory impairment in patients with temporal lobe epilepsyJana Amlerová
Department of Neurology, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol, Prague, Czech Republic
Epilepsy Behav 26:57-60. 2013..The results indicate that not only temporal lobe dysfunction itself but also low general cognitive abilities may contribute to the navigation impairment...
- Spatial navigation impairment is proportional to right hippocampal volumeZuzana Nedelska
Memory Disorders Clinic, Department of Neurology, Charles University in Prague, 2 Faculty of Medicine and Motol University Hospital, 150 06 Prague 5, Czech Republic
Proc Natl Acad Sci U S A 109:2590-4. 2012..The respective real-space and virtual scores strongly correlated with each other. Our findings indicate that the right hippocampus plays a critical role in allocentric navigation, particularly when cognitive impairment is present...
- Disturbance of real space navigation in moderately advanced but not in early Huntington's diseaseVeronika Majerová
Department of Neurology and Center of Clinical Neuroscience, Charles University in Prague, 1st Faculty of Medicine and General University Hospital in Prague, Katerinska 30, 12800 Praha 2, Czech Republic
J Neurol Sci 312:86-91. 2012..Several studies have associated the allocentric navigation with the hippocampus and the egocentric navigation with the striatum. The striatum is predominantly impaired from the early stages of Huntington's disease...
- Spatial navigation-a unique window into physiological and pathological agingIvana Gazova
Department of Neurology, Memory Disorders Clinic, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol Prague 5, Czech Republic
Front Aging Neurosci 4:16. 2012....