I Kralova Lesna

Summary

Country: Czech Republic

Publications

  1. ncbi request reprint Is the amount of coronary perivascular fat related to atherosclerosis?
    I Kralova Lesna
    Laboratory for Atherosclerosis Research, Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
    Physiol Res 64:S435-43. 2015
  2. doi request reprint Could human cold adaptation decrease the risk of cardiovascular disease?
    I Kralova Lesna
    Laboratory for Atherosclerosis Research, Institute for Clinical and Experimental Medicine, Prague, Czech Republic Electronic address
    J Therm Biol 52:192-8. 2015
  3. ncbi request reprint Effect of different types of dietary fatty acids on subclinical inflammation in humans
    I Kralova Lesna
    Institute for Clinical and Experimental Medicine, Prague, Czech Republic
    Physiol Res 62:145-52. 2013
  4. ncbi request reprint HDL and apolipoprotein A1 concentrations as markers of cholesterol efflux in middle-aged women: interaction with smoking
    Ivana Králova Lesná
    Department of Experimental Medicine, Prague, Czech Republic
    Neuro Endocrinol Lett 33:38-42. 2012
  5. ncbi request reprint Effect of rosuvastatin treatment on cholesterol efflux from human macrophages
    Ivana Králova Lesná
    Institute for Clinical and Experimental Medicine, Prague, Czech Republic
    Neuro Endocrinol Lett 32:24-8. 2011
  6. doi request reprint Replacement of dietary saturated FAs by PUFAs in diet and reverse cholesterol transport
    I Kralova Lesna
    Institute for Clinical and Experimental Medicine, Center for Cardiovascular Research, Prague, Czech Republic
    J Lipid Res 49:2414-8. 2008
  7. ncbi request reprint Life style change and reverse cholesterol transport in obese women
    I Kralova Lesna
    Institute for Clinical and Experimental Medicine, Prague, Czech Republic
    Physiol Res 58:S33-8. 2009
  8. ncbi request reprint Macrophage phenotypes in the adipose tissue of postmenopausal women
    A Kralova
    Laboratory for Atherosclerosis Research, Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine IKEM, Prague, Czech Republic
    Physiol Res 64:S427-33. 2015
  9. ncbi request reprint May alcohol-induced increase of HDL be considered as atheroprotective?
    I Kralova Lesna
    Institute for Clinical and Experimental Medicine IKEM, Centre for Cardiovascular Research, Prague, Czech Republic
    Physiol Res 59:407-13. 2010
  10. ncbi request reprint Effect of exercise on markers of vascular health in renal transplant recipients
    J Pitha
    Laboratory for Atherosclerosis Research, Center for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
    Physiol Res 64:945-9. 2015

Collaborators

  • R Poledne
  • J Kovar
  • J A Hubacek
  • V Teplan
  • J Pirk
  • I Striz
  • M Vrablik
  • A Kralova
  • F Thieme
  • S Cejkova
  • L Janousek
  • J Pitha
  • J Zdychova
  • P Suchanek
  • V Adamkova
  • J Fronek
  • A Sekerková
  • P Stavek
  • P Ivak
  • M Schmiedtova
  • D Dlouhá
  • J Maluskova
  • V Lanska
  • M Stollova
  • A Mahrová
  • J Racek
  • I Netuka
  • J Maly
  • L Kazdova
  • Z Dorazilová
  • J Stepankova
  • M Pokorny
  • M Heczková
  • P Wohlfahrt
  • M Veleminsky
  • V Pinekerová
  • P Zimmelová

Detail Information

Publications20

  1. ncbi request reprint Is the amount of coronary perivascular fat related to atherosclerosis?
    I Kralova Lesna
    Laboratory for Atherosclerosis Research, Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
    Physiol Res 64:S435-43. 2015
    ..According to our data interaction between macrophages in the arterial wall and macrophages in surrounding adipose tissue could be more important mechanism of atherogenesis than the size of this tissue itself. ..
  2. doi request reprint Could human cold adaptation decrease the risk of cardiovascular disease?
    I Kralova Lesna
    Laboratory for Atherosclerosis Research, Institute for Clinical and Experimental Medicine, Prague, Czech Republic Electronic address
    J Therm Biol 52:192-8. 2015
    ..Human cold adaptation can influence oxidative stress markers. Trends towards the improvement of cardiovascular risk factors in cold-adapted subjects also indicate the positive effect of cold adaptation on cardio-protective mechanisms. ..
  3. ncbi request reprint Effect of different types of dietary fatty acids on subclinical inflammation in humans
    I Kralova Lesna
    Institute for Clinical and Experimental Medicine, Prague, Czech Republic
    Physiol Res 62:145-52. 2013
    ..It could be stated that the substantial change of dietary fatty acid composition might influence proinflammatory effect in addition to traditional cardiovascular risk factors...
  4. ncbi request reprint HDL and apolipoprotein A1 concentrations as markers of cholesterol efflux in middle-aged women: interaction with smoking
    Ivana Králova Lesná
    Department of Experimental Medicine, Prague, Czech Republic
    Neuro Endocrinol Lett 33:38-42. 2012
    ..In this study, we evaluated whether smoking habits could modify the association of HDL cholesterol and apolipoprotein A1 (ApoA1) with reverse cholesterol transport (RCT), as measured by cholesterol efflux (CHE), in middle-aged women...
  5. ncbi request reprint Effect of rosuvastatin treatment on cholesterol efflux from human macrophages
    Ivana Králova Lesná
    Institute for Clinical and Experimental Medicine, Prague, Czech Republic
    Neuro Endocrinol Lett 32:24-8. 2011
    ..We analyzed the influence of statin induced changes in HDL-C on cholesterol efflux (CHE), the key step affecting the RCT...
  6. doi request reprint Replacement of dietary saturated FAs by PUFAs in diet and reverse cholesterol transport
    I Kralova Lesna
    Institute for Clinical and Experimental Medicine, Center for Cardiovascular Research, Prague, Czech Republic
    J Lipid Res 49:2414-8. 2008
    ..46% vs. 9.53 +/- 1.41%). There was no correlation between individual changes of HDL-C and changes of CHE. It is concluded that the decrease of HDL-C after successful dietary intervention of LDL-C is not accompanied by a decrease of CHE...
  7. ncbi request reprint Life style change and reverse cholesterol transport in obese women
    I Kralova Lesna
    Institute for Clinical and Experimental Medicine, Prague, Czech Republic
    Physiol Res 58:S33-8. 2009
    ..Significant increase of RCT was found in 13 persons with a weight reduction more than 3.5 kg. Substantial weight loss is necessary to increase RCT...
  8. ncbi request reprint Macrophage phenotypes in the adipose tissue of postmenopausal women
    A Kralova
    Laboratory for Atherosclerosis Research, Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine IKEM, Prague, Czech Republic
    Physiol Res 64:S427-33. 2015
    ..This difference was much more pronounced when proinflammatory macrophages with membrane-bound calprotectin were analyzed. ..
  9. ncbi request reprint May alcohol-induced increase of HDL be considered as atheroprotective?
    I Kralova Lesna
    Institute for Clinical and Experimental Medicine IKEM, Centre for Cardiovascular Research, Prague, Czech Republic
    Physiol Res 59:407-13. 2010
    ..51 and 0.60, respectively). In conclusion, moderate alcohol consumption changes the capacity of plasma to induce CHE only at a border line significance...
  10. ncbi request reprint Effect of exercise on markers of vascular health in renal transplant recipients
    J Pitha
    Laboratory for Atherosclerosis Research, Center for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
    Physiol Res 64:945-9. 2015
    ..Therefore, their decrease induced by exercise might reflect stabilization of these processes. ..
  11. ncbi request reprint Actigenetic of ACE gene polymorphism in Czech obese sedentary females
    P Suchanek
    Institute for Clinical and Experimental Medicine, Prague, Czech Republic
    Physiol Res 58:S47-52. 2009
    ..05), thus at least under some circumstances, this genetic variant may have an slight effect on BMI development...
  12. ncbi request reprint Association between duration of the sleep and body weight
    V Adamkova
    Institute for Clinical and Experimental Medicine, Prague, Czech Republic
    Physiol Res 58:S27-31. 2009
    ..001). This association was found both in males and females and in both districts. Other anthropometrical and biochemical parameters were not associated with the sleep duration...
  13. ncbi request reprint The effect of ectopic fat on graft function after living kidney transplantation
    F Thieme
    Transplant Surgery Department, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
    Physiol Res 64:S411-7. 2015
    ..02, r=-0.325, N=58). We confirmed a negative correlation of adiponectin plasma concentration to the BMI of donors. ..
  14. ncbi request reprint Comparison of the relative telomere length measured in leukocytes and eleven different human tissues
    D Dlouhá
    Center for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
    Physiol Res 63:S343-50. 2014
    ..We conclude that the rTL in peripheral leukocytes is not strongly correlated with the rTL in different organs. ..
  15. ncbi request reprint Endothelial dysfunction expressed as endothelial microparticles in patients with end-stage heart failure
    P Ivak
    Institute for Clinical and Experimental Medicine, Prague, Czech Republic
    Physiol Res 63:S369-73. 2014
    ..These results indicate possibility that LVAD do not cause vascular damage 3 months after implantation. Whether these results suggest improvement of vascular wall function and of endothelium is to be proved in long-term studies. ..
  16. ncbi request reprint Adipose tissue and atherosclerosis
    R Poledne
    Laboratory for Atherosclerosis Research, Centre of Experimental Medicine, Institute for Clinical and Experimental Medicine IKEM, Prague, Czech Republic
    Physiol Res 64:S395-402. 2015
    ..The mechanism of this process, the turnover of macrophages in adipose tissue and their direct atherogenic effects all remain to be analyzed. ..
  17. ncbi request reprint Reverse transport of cholesterol is the reason for resistance to development of atherosclerosis in Prague Hereditary Hypercholesterolemic (PHHC) rat
    M Schmiedtova
    Institute of Clinical and Experimental Medicine, Prague, Czech Republic
    Physiol Res 63:591-6. 2014
    ..Increasing release of (14)C-cholesterol efflux from macrophages demonstrates accelerated RTC and leads to prevention of atherogenesis in PHHC rats. ..
  18. ncbi request reprint Co-cultivation of human aortic smooth muscle cells with epicardial adipocytes affects their proliferation rate
    J Zdychova
    Center for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
    Physiol Res 63:S419-27. 2014
    ..05). These results suggest that bioactive substances produced by adipocytes have a stimulatory effect on the proliferation of VSMCs. ..
  19. ncbi request reprint Asymmetric dimethylarginine and endothelial progenitor cells after renal transplantation: the effect of exercise training
    V Teplan
    Department of Nephrology, Transplant Center, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
    Physiol Res 63:S411-7. 2014
    ..02). Next changes in Group I: adiponectin (P<0.01), leptin (P<0.01), resistin (P<0.02). Visfatin, blood lipids, HbA1c, insulin and blood pressure were also influenced by training program (P<0.05). ..
  20. ncbi request reprint Immunological aspects of atherosclerosis
    A Kralova
    Laboratory for Atherosclerosis Research, Centre of Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
    Physiol Res 63:S335-42. 2014
    ..Nevertheless, a positive correlation of both M1 and M2 macrophages with atherosclerotic lesion severity was also observed. ..