M Kalousova

Summary

Country: Czech Republic

Publications

  1. ncbi request reprint Cys327Cys polymorphism of the PAPP-A gene (pregnancy associated plasma protein A) is related to mortality of long term hemodialysis patients
    Marta Kalousova
    Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University in Prague and General University in Prague, Prague, Czech Republic Electronic address
    Clin Biochem 47:578-83. 2014
  2. doi request reprint Placental growth factor, pregnancy-associated plasma protein-A, soluble receptor for advanced glycation end products, extracellular newly identified receptor for receptor for advanced glycation end products binding protein and high mobility group box 1 le
    Oskar Zakiyanov
    Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Prague, Czech Republic
    BMC Nephrol 14:245. 2013
  3. pmc Placental growth factor may predict increased left ventricular mass index in patients with mild to moderate chronic kidney disease--a prospective observational study
    Martina Peiskerová
    Department of Nephrology, First Faculty of Medicine, Charles University, Prague, Czech Republic
    BMC Nephrol 14:142. 2013
  4. doi request reprint Pregnancy-associated plasma protein A: spotlight on kidney diseases
    Marta Kalousova
    Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Prague, Czech Republic
    Clin Chem Lab Med 50:1183-90. 2012
  5. doi request reprint Ferritin as an independent mortality predictor in patients with pancreas cancer. Results of a pilot study
    Marta Kalousova
    Institute of Medical Biochemistry and Laboratory Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Prague, Czech Republic
    Tumour Biol 33:1695-700. 2012
  6. doi request reprint Pregnancy-associated plasma protein A as an independent mortality predictor in long-term hemodialysis patients
    Marta Kalousova
    Institute of Clinical Biochemistry and Laboratory Diagnostics, Charles University and General University Hospital, Prague, Czech Republic
    Kidney Blood Press Res 35:192-201. 2012
  7. ncbi request reprint Pregnancy-associated plasma protein A during hemodialysis with polyamide and diacetate cellulosic membranes
    M Kalousova
    Institute of Medical Biochemistry, Department of Nephrology, 1st Faculty of Medicine and General University Hospital, Charles University, Prague Czech Republic
    Int J Artif Organs 27:943-8. 2004
  8. doi request reprint Lower retinol levels as an independent predictor of mortality in long-term hemodialysis patients: a prospective observational cohort study
    Marta Kalousova
    Institute of Clinical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University in Prague, General University Hospital in Prague, Czech Republic
    Am J Kidney Dis 56:513-21. 2010
  9. ncbi request reprint [Advanced glycation and oxidation products in patients with atherosclerosis]
    M Kalousova
    Ustav lékarské biochemie 1 LF UK, Praha
    Cas Lek Cesk 144:385-9; discussion 389-90. 2005
  10. ncbi request reprint Advanced glycoxidation end products in chronic diseases-clinical chemistry and genetic background
    Marta Kalousova
    Institute of Clinical Chemistry and Laboratory Diagnostics, First Faculty of Medicine and General University Hospital, Charles University, Katerinska 32, 12108 Prague 2, Czech Republic
    Mutat Res 579:37-46. 2005

Collaborators

Detail Information

Publications63

  1. ncbi request reprint Cys327Cys polymorphism of the PAPP-A gene (pregnancy associated plasma protein A) is related to mortality of long term hemodialysis patients
    Marta Kalousova
    Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University in Prague and General University in Prague, Prague, Czech Republic Electronic address
    Clin Biochem 47:578-83. 2014
    ..The aim of the study was to test the role of these PAPP-A SNPs in long term hemodialysis patients...
  2. doi request reprint Placental growth factor, pregnancy-associated plasma protein-A, soluble receptor for advanced glycation end products, extracellular newly identified receptor for receptor for advanced glycation end products binding protein and high mobility group box 1 le
    Oskar Zakiyanov
    Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Prague, Czech Republic
    BMC Nephrol 14:245. 2013
    ..However, their clinical significance in acute kidney injury (AKI) is unknown. The aim of this cross-sectional study was to determine whether selected biomarkers are changed in AKI patients...
  3. pmc Placental growth factor may predict increased left ventricular mass index in patients with mild to moderate chronic kidney disease--a prospective observational study
    Martina Peiskerová
    Department of Nephrology, First Faculty of Medicine, Charles University, Prague, Czech Republic
    BMC Nephrol 14:142. 2013
    ..The aim of our study was to determine the possible association of PlGF and several other CV risk markers to echocardiographic parameters in CKD population...
  4. doi request reprint Pregnancy-associated plasma protein A: spotlight on kidney diseases
    Marta Kalousova
    Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Prague, Czech Republic
    Clin Chem Lab Med 50:1183-90. 2012
    ..Various assays for PAPP-A exist and the type of assay used in a study should be considered. This article reviews the data summarizing basic information about PAPP-A with a particular focus on the significance of PAPP-A in renal diseases...
  5. doi request reprint Ferritin as an independent mortality predictor in patients with pancreas cancer. Results of a pilot study
    Marta Kalousova
    Institute of Medical Biochemistry and Laboratory Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Prague, Czech Republic
    Tumour Biol 33:1695-700. 2012
    ..073). This study points out ferritin as an independent mortality predictor in patients with pancreas cancer. High serum levels of ferritin at the time of diagnosis of pancreas cancer indicate bad prognosis of the patient...
  6. doi request reprint Pregnancy-associated plasma protein A as an independent mortality predictor in long-term hemodialysis patients
    Marta Kalousova
    Institute of Clinical Biochemistry and Laboratory Diagnostics, Charles University and General University Hospital, Prague, Czech Republic
    Kidney Blood Press Res 35:192-201. 2012
    ..Pregnancy-associated plasma protein A (PAPP-A) is a biomarker related to vascular damage. The aim of the study was to focus on PAPP-A and related parameters and their relationship to the prognosis of long-term hemodialysis (HD) patients...
  7. ncbi request reprint Pregnancy-associated plasma protein A during hemodialysis with polyamide and diacetate cellulosic membranes
    M Kalousova
    Institute of Medical Biochemistry, Department of Nephrology, 1st Faculty of Medicine and General University Hospital, Charles University, Prague Czech Republic
    Int J Artif Organs 27:943-8. 2004
    ..During dialysis, it might be destroyed or cleaved and removed as free fragments. Its levels both before and after the HD session are higher than in healthy subjects...
  8. doi request reprint Lower retinol levels as an independent predictor of mortality in long-term hemodialysis patients: a prospective observational cohort study
    Marta Kalousova
    Institute of Clinical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University in Prague, General University Hospital in Prague, Czech Republic
    Am J Kidney Dis 56:513-21. 2010
    ..In this study, we focus on antioxidant vitamins and trace elements and the relationship of their serum levels to the prognosis of long-term HD patients...
  9. ncbi request reprint [Advanced glycation and oxidation products in patients with atherosclerosis]
    M Kalousova
    Ustav lékarské biochemie 1 LF UK, Praha
    Cas Lek Cesk 144:385-9; discussion 389-90. 2005
    ..The aim of the study was to determine AGEs and AOPP in patients with atherosclerosis, effect of statin therapy and relationship to parameters of lipid metabolism...
  10. ncbi request reprint Advanced glycoxidation end products in chronic diseases-clinical chemistry and genetic background
    Marta Kalousova
    Institute of Clinical Chemistry and Laboratory Diagnostics, First Faculty of Medicine and General University Hospital, Charles University, Katerinska 32, 12108 Prague 2, Czech Republic
    Mutat Res 579:37-46. 2005
    ....
  11. ncbi request reprint Advanced glycoxidation end products in patients with multiple sclerosis
    M Kalousova
    Institute of Medical Biochemistry of the First Faculty of Medicine, Charles University in Prague, Czech Republic
    Prague Med Rep 106:167-74. 2005
    ..Other compounds and ligands of RAGE are probably of higher significance in MS...
  12. ncbi request reprint Advanced glycation end-products in patients with chronic alcohol misuse
    Marta Kalousova
    Institute of Medical Biochemistry, First Faculty of Medicine, Charles University, Katerinska 32, 121 08 Prague 2, Czech Republic
    Alcohol Alcohol 39:316-20. 2004
    ..The aim of our study was to determine serum levels of advanced glycation end-products (AGE) in patients with chronic alcohol misuse and to examine their relationship to markers of nutrition and inflammation...
  13. doi request reprint RAGE polymorphisms, renal function and histological finding at 12 months after renal transplantation
    Marta Kalousova
    Institute of Clinical Chemistry and Laboratory Diagnostics, First Faculty of Medicine and General University Hospital, Charles University, Karlovo nam 32, 121 11 Prague 2, Czech Republic
    Clin Biochem 42:347-52. 2009
    ..Rage (receptor for advanced glycation end products) is involved in pathogenesis of many diseases. The aim of the study was to test whether polymorphisms of RAGE gene are associated with the outcome of kidney transplantation...
  14. ncbi request reprint A419C (E111A) polymorphism of the glyoxalase I gene and vascular complications in chronic hemodialysis patients
    Marta Kalousova
    Institute of Clinical Chemistry and Laboratory Diagnostics, First Faculty of Medicine and General University Hospital, Charles University, Prague, Czech Republic
    Ann N Y Acad Sci 1126:268-71. 2008
    ..In summary, in this study we demonstrate for the first time the association of A419C polymorphism of the glyoxalase I gene with sRAGE levels and show the genetic predisposition to vascular complications in HD patients...
  15. doi request reprint Genetic predisposition to advanced glycation end products toxicity is related to prognosis of chronic hemodialysis patients
    Marta Kalousova
    Institute of Clinical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Prague, Czech Republic
    Kidney Blood Press Res 33:30-6. 2010
    ..The A419C (E111A) polymorphism of the GLO I gene is associated with vascular disease in hemodialysis (HD) patients and some RAGE gene polymorphisms are implicated in various pathological states...
  16. ncbi request reprint Receptor for advanced glycation end products--soluble form and gene polymorphisms in chronic haemodialysis patients
    Marta Kalousova
    Institute of Clinical Chemistry and Laboratory Diagnostics, Department of Nephrology, 1st Faculty of Medicine and General University Hospital, Charles University, Karlovo nam 32, 121 11 Prague 2, Czech Republic
    Nephrol Dial Transplant 22:2020-6. 2007
    ..The pathological effects mediated via RAGE are physiologically inhibited by soluble RAGE (sRAGE). Our aim was to study sRAGE and RAGE gene polymorphisms in haemodialysis (HD) patients...
  17. ncbi request reprint Pregnancy-associated plasma protein a and soluble receptor for advanced glycation end products after kidney transplantation
    Marta Kalousova
    Institute of Clinical Chemistry and Laboratory Diagnostics, First Faculty of Medicine and General University Hospital, Charles University, Prague, Czech Republic
    Kidney Blood Press Res 30:31-7. 2007
    ..Pregnancy-associated plasma protein A (PAPP-A) and soluble receptor for advanced glycation end products (sRAGE) are new markers related to vascular damage...
  18. ncbi request reprint Increased levels of pregnancy-associated plasma protein A are associated with mortality in hemodialysis patients: preliminary results
    M Kalousova
    Institute of Medical Biochemistry, 1st Faculty of Medicine and General Faculty Hospital, Charles University, Prague, Czech Republic
    Blood Purif 22:298-300. 2004
    ..8) vs. 20 (14.9-26.6) mU/l, p = 0.034. PAPP-A could also be a new prognostic marker in hemodialysis patients, probably due to its close association with cardiovascular risk. More extensive studies are required to confirm this hypothesis...
  19. ncbi request reprint Soluble receptor for advanced glycation end products in patients with decreased renal function
    Marta Kalousova
    Institute of Clinical Chemistry and Laboratory Medicine, Department of Nephrology, First Faculty of Medicine, General University Hospital, Charles University, Prague, Czech Republic
    Am J Kidney Dis 47:406-11. 2006
    ..Soluble RAGE (sRAGE) is a naturally occurring inhibitor of AGE-RAGE action. The aim of the study is to describe the relationship of sRAGE to renal function and dialysis modalities...
  20. ncbi request reprint Relationship of pregnancy-associated plasma protein-a to renal function and dialysis modalities
    L Fialova
    Institute of Medical Biochemistry, First Faculty of Medicine, Charles University, Prague, Czech Republic
    Kidney Blood Press Res 27:88-95. 2004
    ....
  21. ncbi request reprint Oxidative stress and inflammation in pregnancy
    L Fialova
    Institute of Medical Biochemistry, Charles University, Prague, Czech Republic
    Scand J Clin Lab Invest 66:121-7. 2006
    ..504, p<0.05). The increased levels of AOPPs, CRP and ACA IgG in the 1st and 2nd trimesters may reflect a maternal response to inflammatory and oxidative stress in pregnant women...
  22. ncbi request reprint Advanced glycation end products in clinical nephrology
    M Kalousova
    Institute of Medical Biochemistry, 1st Faculty of Medicine and University Hospital, Charles University, Prague, Czech Republic
    Kidney Blood Press Res 27:18-28. 2004
    ..g. aminoguanidine, OPB-9195, pyridoxamine, antioxidants, N-phenacylthiazolium bromide, antihypertensive drugs, angiotensin-converting enzyme inhibitors and angiotensin II receptor-1 antagonists)...
  23. ncbi request reprint [Levels of advanced oxidation protein products (AOPP) in the first trimester of pregnancy]
    L Fialova
    Ustav lékarské biochemie, Katerinska 32, 121 08 Praha 2, Czech Republic
    Sb Lek 104:95-102. 2003
    ..Higher levels of AOPP in the serum of pregnant women in comparison with women--blood donors may reflect an increase of oxidative stress in pregnancy...
  24. ncbi request reprint Markers of inflammation in preeclampsia
    L Fialova
    Institute of Medical Biochemistry of the First Faculty of Medicine, Charles University in Prague, Czech Republic
    Prague Med Rep 105:301-10. 2004
    ..708, P<0.05). The results indicate enhanced oxidative and inflammatory reaction of maternal organism to pregnancy, which is more pronounced in preeclampsia than in uncomplicated pregnancy...
  25. ncbi request reprint Advanced glycation end products and advanced oxidation protein products in hemodialyzed patients
    M Kalousova
    1st Institute of Medical Chemistry and Biochemistry, 1st Faculty of Medicine, Charles University, Katerinska 32, CZ 121 08 Prague 2, Czech Republic
    Blood Purif 20:531-6. 2002
    ..62, p < 0.05) but not after the session (r = 0.29, not significant). According to our results, AGEs may serve more as a marker of chronic damage while AOPP may better describe acute oxidative stress during the dialysis treatment...
  26. ncbi request reprint Oxidative stress, inflammation and autoimmune reaction in type 1 and type 2 diabetes mellitus
    M Kalousova
    Institute of Medical Biochemistry, Charles University, and General Teaching Hospital, Prague, Czech Republic
    Prague Med Rep 105:21-8. 2004
    ..45, p<0.05). Oxidative stress and inflammation are more expressed in DM2 and they are partly related. In DM1, oxidative stress seems to be in closer link to autoimmune reaction than to inflammation...
  27. doi request reprint Glyoxalase I Glu111Ala polymorphism in patients with breast cancer
    Alexandra Germanova
    Institute of Clinical Chemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic
    Cancer Invest 27:655-60. 2009
    ..05). The presence of the C allele could represent a negative prognostic factor; however, further studies are needed to confirm this hypothesis...
  28. ncbi request reprint Carbonyl and oxidative stress in patients with breast cancer--is there a relation to the stage of the disease?
    P Tesarova
    Department of Oncology, 1st School of Medicine and General Faculty Hospital, Prague, Czech Republic
    Neoplasma 54:219-24. 2007
    ..As the clinical significance of these observations is currently uncertain further studies are clearly warranted, especially with respect to their potential therapeutic implications...
  29. doi request reprint Fibroblast growth factor 23 and matrix-metalloproteinases in patients with chronic kidney disease: are they associated with cardiovascular disease?
    M Peiskerová
    Department of Nephrology, First Faculty of Medicine, Charles University, Hradec Kralove, Czech Republic mpeiskerova seznam cz
    Kidney Blood Press Res 32:276-83. 2009
    ..FGF-23 and MMPs levels are altered in CKD, however, little is known about their association and relation to cardiovascular (CV) disease...
  30. ncbi request reprint Does renal function influence plasma levels of advanced glycation and oxidation protein products in patients with chronic rheumatic diseases complicated by secondary amyloidosis?
    Romana Rysava
    Department of Nephrology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic
    Kidney Blood Press Res 30:1-7. 2007
    ....
  31. ncbi request reprint Pregnancy-associated plasma protein-A in patients with cerebrovascular diseases--a pilot study
    L Fialova
    Institute of Medical Biochemistry of the First Faculty of Medicine, Charles University in Prague, Czech Republic
    Prague Med Rep 107:37-45. 2006
    ..The atherosclerotic process may contribute to increased serum PAPP-A levels. PAPP-A may be a marker of increased risk of atherothrombotic events in general...
  32. ncbi request reprint Levels of circulating biomarkers at rest and after exercise in coronary artery disease patients
    V Danzig
    Second Department of Medicine, First Faculty of Medicine, General University Hospital, Charles University, Prague, Czech Republic
    Physiol Res 59:385-92. 2010
    ..MMP-9 and BNP increase significantly with exercise in both healthy individuals and CAD patients...
  33. ncbi request reprint [New markers of advanced damage caused by oxidative and carbonyl stress]
    M Kalousova
    Ustav lékrské chemie a biochemie 1 lékarské fakulty Univerzity Karlovy, Katerinska 32, 121 08 Praha 20, Czech Republic
    Sb Lek 102:465-72. 2001
    ..These compounds have several biological effects--e.g. stimulation of secretion of cytokines, adhesive molecules and growth factors and take part in the development of complications of diabetes mellitus and chronic renal failure...
  34. ncbi request reprint Prenatal and perinatal management of preterm labour
    M Koucký
    Charles University in Prague, First Faculty of Medicine and General University Hospital, Department of Gynaecology and Obstetrics, Prague, Czech Republic
    Prague Med Rep 110:269-77. 2009
    ....
  35. ncbi request reprint Thyroid hormone abnormalities in hemodialyzed patients: low triiodothyronine as well as high reverse triiodothyronine are associated with increased mortality
    J Horacek
    Department of Internal Medicine IV, Faculty of Medicine and University Hospital Hradec Kralove, Charles University in Prague, Hradec Kralove, Czech Republic
    Physiol Res 61:495-501. 2012
    ..021). Increased rT3 may be more common in ESRD patients than previously described, and together with decreased T3 it may serve as an indicator of poor prognosis in subsequent months...
  36. ncbi request reprint Pregnancy-associated plasma protein A polymorphisms in patients with risk pregnancies
    A Germanova
    Charles University in Prague, Institute of Clinical Chemistry and Laboratory Diagnostics, Prague, Czech Republic
    Folia Biol (Praha) 57:82-5. 2011
    ..However, further studies with a larger group of subjects are needed to confirm our results...
  37. ncbi request reprint Advanced glycation end-products and advanced oxidation protein products in patients with diabetes mellitus
    M Kalousova
    First Institute of Medical Chemistry and Biochemistry, First Faculty of Medicine, Charles University, Katerinská Prague, Czech Republic
    Physiol Res 51:597-604. 2002
    ..Oxidative stress is increased in both types of DM, more in Type 2 where it contributes to the formation of glycoxidation products...
  38. doi request reprint Relationship of soluble RAGE and RAGE ligands HMGB1 and EN-RAGE to endothelial dysfunction in type 1 and type 2 diabetes mellitus
    J Skrha
    Institute of Clinical Biochemistry and Laboratory Diagnostics, 1st Faculty of Medicine, Charles University in Prague, U Nemocnice 1, Prague, Czech Republic
    Exp Clin Endocrinol Diabetes 120:277-81. 2012
    ..001). Significant positive correlation was found between sRAGE and ICAM-1, VCAM-1 or vWF (p<0.01 to p<0.001).We conclude that serum sRAGE and RAGE ligands concentrations reflect endothelial dysfunction developing in diabetes...
  39. ncbi request reprint Decreased levels of advanced glycation end-products in patients with Gilbert syndrome
    M Kalousova
    Institute of Clinical Biochemistry, Laboratory Diagnostics, Charles University, Prague, Czech Republic
    Cell Mol Biol (Noisy-le-grand) 51:387-92. 2005
    ..In subjects with GS elevated serum bilirubin concentrations are associated with lower levels of AGEs. These results are in support of previous data on antioxidant properties of bilirubin...
  40. pmc Skin autofluorescence relates to soluble receptor for advanced glycation end-products and albuminuria in diabetes mellitus
    J Skrha
    Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University in Prague, General University Hospital in Prague, 128 08 Prague 2, Czech Republic 3rd Department of Internal Medicine, First Faculty of Medicine, Charles University in Prague, General University Hospital in Prague, 128 08 Prague 2, Czech Republic
    J Diabetes Res 2013:650694. 2013
    ..The strong and independent relationship between AF and sRAGE supports the idea that AF may reflect AGEs/RAGE interactions. The exact mechanism remains to be established...
  41. doi request reprint Fetuin-A early after renal transplantation
    M Urbanova
    Department of Nephrology, Transplant Center, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
    Kidney Blood Press Res 32:217-22. 2009
    ..Its deficiency, common in end-stage renal disease, has been suggested to be associated with cardiovascular complications. The aim of this study was to monitor fetuin-A levels in the early period after renal transplantation...
  42. ncbi request reprint [Acute phase proteins in female patients with breast carcinoma]
    P Tesarova
    Onkologická, Klinika, 1 lékarské fakulty Univerzity Karlovy a Vseobecné fakultní nemocnice, U nemocnice 2, 128 08 Praha 2, Czech Republic
    Sb Lek 104:121-32. 2003
    ....
  43. ncbi request reprint [Soluble adhesion molecules in female patients with breast carcinoma]
    P Tesarova
    I interní klinika 1 LF UK a VFN, Praha
    Cas Lek Cesk 142:292-9. 2003
    ..We wanted to find out if these parameters differ between various stages of breast cancer and if their levels are influenced by the therapy...
  44. ncbi request reprint Influence of parenteral iron therapy and oral vitamin E supplementation on neutrophil respiratory burst in chronic hemodialysis patients
    Magdalena Hodkova
    Department of Medicine Strahov, Institute of Medical Biochemistry, General Teaching Hospital, and 1st Faculty of Medicine, Charles University, Prague, Czech Republic
    Ren Fail 27:135-41. 2005
    ..The aim of our study was to monitor neutrophil respiratory burst during HD and to find out whether this process is influenced by IV Fe and oral vitamin E administration...
  45. ncbi request reprint Receptor for advanced glycation end products (RAGE)--soluble form (sRAGE) and gene polymorphisms in patients with breast cancer
    Petra Tesarova
    Department of Oncology, 1st School of Medicine, Charles University and General University Hospital, Prague, Czech Republic
    Cancer Invest 25:720-5. 2007
    ..Patients with better outcome (low grade and positive estrogen receptors) have higher sRAGE levels. Progression of the disease, may, however, increase sRAGE levels, possibly as a compensatory mechanism to counteract further progression...
  46. ncbi request reprint Influence of oral vitamin E therapy on micro-inflammation and cardiovascular disease markers in chronic hemodialysis patients
    Magdalena Hodkova
    Department of Nephrology, Institute of Clinical Chemistry and Laboratory Diagnostics, General Teaching Hospital and First Faculty of Medicine, Charles University, Prague, Czech Republic
    Ren Fail 28:395-9. 2006
    ..The aim of this study was to evaluate the influence of oral vitamin E therapy on serum concentrations of several markers of micro-inflammation and cardiovascular disease in chronic hemodialysis (HD) patients...
  47. ncbi request reprint Intravenous iron gluconate administration increases circulating PAPP-A in hemodialysis patients
    Magdalena Hodkova
    Institute of Medical Biochemistry, Ist Faculty of Medicine, Charles University, Prague, Czech Republic
    Ren Fail 27:707-11. 2005
    ..As intravenous (IV) iron might enhance oxidative stress in HD patients, this study investigates circulating PAPP-A during HD session and after IV iron administration...
  48. ncbi request reprint Advanced glycation end products in hemodialyzed patients with diabetes mellitus correlate with leptin and leptin/body fat ratio
    Marta Kalousova
    Institute of Medical Biochemistry, 1st Faculty of Medicine, Charles University and University Hospital, Prague, Czech Republic
    Ren Fail 25:277-86. 2003
    ..These findings suggest more detailed studies to identify the molecular links between carbonyl stress, i.e., advanced glycation end products, and leptin metabolism, sign of microinflammation and hypertension...
  49. ncbi request reprint Effect of hemodiafiltration on pregnancy-associated plasma protein A (PAPP-A) and related parameters
    Marta Kalousova
    Institute of Clinical Chemistry and Laboratory Diagnostics, 1st Faculty of Medicine, Charles University and General University Hospital, Karlovo nam 32, 121 11 Prague 2, Czech Republic
    Ren Fail 28:715-21. 2006
    ....
  50. doi request reprint Soluble receptor for advanced glycation end-products (sRAGE) and polymorphisms of RAGE and glyoxalase I genes in patients with pancreas cancer
    Tomas Krechler
    Department of Medicine IV Department of Gastroenterology and Hepatology, 1st Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic
    Clin Biochem 43:882-6. 2010
    ..sRAGE, soluble RAGE, is an inhibitor of pathological effects mediated via RAGE. The aim was to study sRAGE and polymorphisms of RAGE (AGER) and GLO genes in patients with pancreas cancer (PC)...
  51. doi request reprint Detection of feto-maternal infection/inflammation by the soluble receptor for advanced glycation end products (sRAGE): results of a pilot study
    Zdenek Hajek
    Department of Obstetrics and Gynecology, 1st Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic
    J Perinat Med 36:399-404. 2008
    ..The aim of this study was to assess the usefulness of measuring sRAGE concentration in pregnant women with threatening preterm labor...
  52. ncbi request reprint Concentrations of sRAGE in serum and follicular fluid in assisted reproductive cycles--a preliminary study
    Karin Malickova
    Institute of Clinical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Czech Republic
    Clin Lab 56:377-84. 2010
    ....
  53. ncbi request reprint Advanced oxidation protein products in obstructive sleep apnea
    K Sonka
    Department of Neurology, Charles University in Prague, First Faculty of Medicine and General Teaching Hospital, Prague, Czech Republic
    Prague Med Rep 109:159-65. 2008
    ..2 (SD=35.3) pmol/l, the difference was not significant. The AOPP were found correlated with the AHI (apnoe/hypopnoe index) (R=0.485, P=0.030). The results support the hypothesis that OSA increases the oxidative stress and atherogenesis...
  54. doi request reprint Circulating fetuin-A predicts early mortality in chronic hemodialysis patients
    Vladimir Blaha
    Department Metabolism and Gerontology, University Hospital and Medical Faculty, Charles University, Hradec Kralove, Czech Republic
    Clin Biochem 42:996-1000. 2009
    ..The purpose of this study was to assess whether low serum levels of fetuin-A are potential biochemical predictor of early and/or late survival in chronic hemodialysis (HD) patients...
  55. ncbi request reprint 2,3,7,8-TCDD exposure, endothelial dysfunction and impaired microvascular reactivity
    Daniela Pelclova
    Department of Occupational Medicine, 1st Medical Faculty, Charles University and General University Hospital, Na Bojisti 1, Prague, Czech Republic
    Hum Exp Toxicol 26:705-13. 2007
    ..77, P = 0.009) as well as the velocity of perfusion increase during TH (r = -0.68, P = 0.03) and TH% (r = -0.78, P = 0.008). Our data document the presence of endothelial dysfunction in TCDD-exposed men...
  56. ncbi request reprint Comparison of three methods for determination of glucose
    L Dohnal
    Reference Laboratory for Clinical Chemistry of the Czech Ministry of Health, Prague, Czech Republic
    Prague Med Rep 111:42-54. 2010
    ..For glucose 8 mmol/l and lower, comparability of results given by HKL, GDL and GL methods gradually worsens, while for glucose between 8 and 34 mmol/l results of the three mentioned methods are well comparable...
  57. ncbi request reprint Pathophysiology of preterm labour
    M Koucký
    Charles University in Prague, First Faculty of Medicine and General Teaching Hospital, Department of Gynaecology and Obstetrics, Apolinarska 18, 128 00 Prague 2, Czech Republic
    Prague Med Rep 110:13-24. 2009
    ..Intensive research of potential trigger mechanisms has been carried out, including a variety of gene types, which are potentially related to the process of premature delivery...
  58. ncbi request reprint Is maternal progesterone actually independent of the fetal steroids?
    M Hill
    Institute of Endocrinology, Prague, Czech Republic
    Physiol Res 59:211-24. 2010
    ....
  59. ncbi request reprint Oxidative stress and signal transduction pathways in alcoholic liver disease
    Tomas Zima
    Institute of Clinical Chemistry and Laboratory Diagnostics, 1st Faculty of Medicine and General University Hospital, Charles University, Prague, Czech Republic
    Alcohol Clin Exp Res 29:110S-115S. 2005
    ..We are only at the beginning .....
  60. doi request reprint Soluble receptor for advanced glycation end products in physiological and pathological pregnancy
    Anna Germanova
    Institute of Clinical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Czech Republic
    Clin Biochem 43:442-6. 2010
    ..Soluble RAGE, sRAGE, extracellular domain of RAGE, is new biomarker. The aim of the study was to determine sRAGE levels in physiological pregnancy and their changes in pregnancies complicated by preterm labor or preeclampsia...
  61. doi request reprint Anti-inflammatory effect of biological treatment in patients with inflammatory bowel diseases: calprotectin and IL-6 changes do not correspond to sRAGE changes
    Karin Malickova
    Clinical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Czech Republic
    Scand J Clin Lab Invest 70:294-9. 2010
    ....
  62. ncbi request reprint Oxidative stress and endothelium influenced by metformin in type 2 diabetes mellitus
    Jan Skrha
    Laboratory for Endocrinology and Metabolism, 3rd Department of Internal Medicine, First Faculty of Medicine, Charles University, U Nemocnice 1, 128 08 Prague 2, Czech Republic
    Eur J Clin Pharmacol 63:1107-14. 2007
    ..Metformin may influence atherogenesis but the mechanisms are not well understood. A pilot study was undertaken to determine whether metformin administration is associated with changes in oxidative stress and endothelial function...
  63. doi request reprint Evaluation of skin microcirculation during hemodialysis
    Erik Mistrik
    Department of Gerontology, Nephrology and Metabolism, University Hospital and Medical Faculty, Charles University, Hradec Kralove, Czech Republic
    Ren Fail 32:21-6. 2010
    ..Peripheral ischemic vascular disease represents a serious problem with high mortality and morbidity. We estimated skin microcirculation changes during HD using new device, Laser Doppler Line Scanner (Moor Instruments, Devon, UK)...