Research Topics
| Alla SynytsyaSummaryAffiliation: Institute of Chemical Technology Country: Czech Republic Publications
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Detail Information
Publications
In vitro interaction of macrocyclic photosensitizers with intact mitochondria: a spectroscopic studyAlla Synytsya
Faculty of Chemical Technology, Department of Analytical Chemistry, Institute of Chemical Technology, Technicka 5, 166 28 Prague 6, Czech Republic
Biochim Biophys Acta 1620:85-96. 2003..Obtained spectroscopic results confirm that the binding process altered the self-aggregation degree of expanded porphyrins...- Biodistribution assessment of a lutetium(III) texaphyrin analogue in tumor-bearing mice using NIR Fourier-transform Raman spectroscopyAlla Synytsya
Department of Analytical Chemistry, Institute of Chemical Technology, Prague, Czech Republic
Photochem Photobiol 79:453-60. 2004..Maximal drug content was observed 3 days after the final injection. This time delay seems to be optimal for tumor irradiation in photodynamic therapy... - Interaction of meso-tetrakis(4-sulphonatophenyl)porphine with chitosan in aqueous solutionsAlla Synytsya
Department of Analytical Chemistry, Institute of Chemical Technology in Prague, Technická 3 5, 166 28 Prague 6, Czech Republic
Spectrochim Acta A Mol Biomol Spectrosc 66:225-35. 2007..The complex nature of CD bands assigned to both types of porphyrin aggregates indicated the occurrence of several chiral macrocyclic species dependently on pH value and chitosan concentration... 
pH-controlled self-assembling of meso-tetrakis(4-sulfonatophenyl)porphyrin-chitosan complexesAlla Synytsya
Department of Analytical Chemistry, Institute of Chemical Technology, Prague 16628, Czech Republic
Biomacromolecules 10:1067-76. 2009..Based on structural inferences, self-assembling hierarchy models were proposed for both of the TPPS(4)-chitosan supramolecular complexes...- Synthesis and biolocalization of water-soluble sapphyrinsVladimir Kral
Department of Analytical Chemistry, Institute of Chemical Technology, Technicka 5, 166 28 Prague, Czech Republic
J Med Chem 45:1073-8. 2002..The concentrations of the water-soluble sapphyrins reported here, as well as a porphyrin control system, were determined as a function of time and tissue type... - Modification of chitosan-methylcellulose composite films with meso-tetrakis(4-sulfonatophenyl)porphyrinAlla Synytsya
Department of Analytical Chemistry, Institute of Chemical Technology in Prague, 166 28 Prague, The Czech Republic
Biomacromolecules 13:489-98. 2012..ECD measurements detected the presence of optically active porphyrin species bound to the films. SEM and AFM images confirmed that the porphyrin macrocycles caused structural changes on the film surface and within the film layer... - Biolocalisation and photochemical properties of two novel macrocyclic photosensitisers: a spectroscopic studyAlla Synytsya
Department of Analytical Chemistry, Institute of Chemical Technology in Prague, Technicka 5, 166 28 Prague 6, Czech Republic
J Photochem Photobiol B 74:73-84. 2004..Raman spectroscopic study indicated that monomerised photosensitiser 2 effectively damaged BSA and calf thymus DNA after light excitation at the conditions of high excess of these macromolecules... - Novel porphyrin conjugates with a potent photodynamic antitumor effect: differential efficacy of mono- and bis-beta-cyclodextrin derivatives in vitro and in vivoJarmila Kralova
Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague, Czech Republic
Photochem Photobiol 82:432-8. 2006..Thus, P(beta-CD)2 represents a new photosensitizing drug displaying fast and selective tumor uptake, strong antitumor activity and fast elimination from the body... - The complexation of metal cations by D-galacturonic acid: a spectroscopic studyAndriy Synytsya
Department of Carbohydrate Chemistry and Technology, Institute of Chemical Technology, Technická 3 5, 166 28 Prague 6, Czech Republic
Carbohydr Res 339:2391-405. 2004..Possible ways of GalA coordination by metal cations of this study were proposed and discussed...