Alla Synytsya

Summary

Affiliation: Institute of Chemical Technology
Country: Czech Republic

Publications

  1. ncbi request reprint In vitro interaction of macrocyclic photosensitizers with intact mitochondria: a spectroscopic study
    Alla Synytsya
    Faculty of Chemical Technology, Department of Analytical Chemistry, Institute of Chemical Technology, Technicka 5, 166 28 Prague 6, Czech Republic
    Biochim Biophys Acta 1620:85-96. 2003
  2. ncbi request reprint Biodistribution assessment of a lutetium(III) texaphyrin analogue in tumor-bearing mice using NIR Fourier-transform Raman spectroscopy
    Alla Synytsya
    Department of Analytical Chemistry, Institute of Chemical Technology, Prague, Czech Republic
    Photochem Photobiol 79:453-60. 2004
  3. ncbi request reprint Interaction of meso-tetrakis(4-sulphonatophenyl)porphine with chitosan in aqueous solutions
    Alla Synytsya
    Department of Analytical Chemistry, Institute of Chemical Technology in Prague, Technická 3 5, 166 28 Prague 6, Czech Republic
    Spectrochim Acta A Mol Biomol Spectrosc 66:225-35. 2007
  4. doi request reprint pH-controlled self-assembling of meso-tetrakis(4-sulfonatophenyl)porphyrin-chitosan complexes
    Alla Synytsya
    Department of Analytical Chemistry, Institute of Chemical Technology, Prague 16628, Czech Republic
    Biomacromolecules 10:1067-76. 2009
  5. ncbi request reprint Synthesis and biolocalization of water-soluble sapphyrins
    Vladimir Kral
    Department of Analytical Chemistry, Institute of Chemical Technology, Technicka 5, 166 28 Prague, Czech Republic
    J Med Chem 45:1073-8. 2002
  6. doi request reprint Modification of chitosan-methylcellulose composite films with meso-tetrakis(4-sulfonatophenyl)porphyrin
    Alla Synytsya
    Department of Analytical Chemistry, Institute of Chemical Technology in Prague, 166 28 Prague, The Czech Republic
    Biomacromolecules 13:489-98. 2012
  7. ncbi request reprint Biolocalisation and photochemical properties of two novel macrocyclic photosensitisers: a spectroscopic study
    Alla Synytsya
    Department of Analytical Chemistry, Institute of Chemical Technology in Prague, Technicka 5, 166 28 Prague 6, Czech Republic
    J Photochem Photobiol B 74:73-84. 2004
  8. ncbi request reprint Novel porphyrin conjugates with a potent photodynamic antitumor effect: differential efficacy of mono- and bis-beta-cyclodextrin derivatives in vitro and in vivo
    Jarmila Kralova
    Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague, Czech Republic
    Photochem Photobiol 82:432-8. 2006
  9. ncbi request reprint The complexation of metal cations by D-galacturonic acid: a spectroscopic study
    Andriy Synytsya
    Department of Carbohydrate Chemistry and Technology, Institute of Chemical Technology, Technická 3 5, 166 28 Prague 6, Czech Republic
    Carbohydr Res 339:2391-405. 2004
  10. doi request reprint Analysis of human blood plasma and hen egg white by chiroptical spectroscopic methods (ECD, VCD, ROA)
    Alla Synytsya
    Department of Analytical Chemistry, Institute of Chemical Technology Prague, Technicka 5, 166 28, Prague 6, Czech Republic
    Anal Bioanal Chem 405:5441-53. 2013

Collaborators

Detail Information

Publications10

  1. ncbi request reprint In vitro interaction of macrocyclic photosensitizers with intact mitochondria: a spectroscopic study
    Alla Synytsya
    Faculty of Chemical Technology, Department of Analytical Chemistry, Institute of Chemical Technology, Technicka 5, 166 28 Prague 6, Czech Republic
    Biochim Biophys Acta 1620:85-96. 2003
    ..Obtained spectroscopic results confirm that the binding process altered the self-aggregation degree of expanded porphyrins...
  2. ncbi request reprint Biodistribution assessment of a lutetium(III) texaphyrin analogue in tumor-bearing mice using NIR Fourier-transform Raman spectroscopy
    Alla Synytsya
    Department of Analytical Chemistry, Institute of Chemical Technology, Prague, Czech Republic
    Photochem Photobiol 79:453-60. 2004
    ..Maximal drug content was observed 3 days after the final injection. This time delay seems to be optimal for tumor irradiation in photodynamic therapy...
  3. ncbi request reprint Interaction of meso-tetrakis(4-sulphonatophenyl)porphine with chitosan in aqueous solutions
    Alla Synytsya
    Department of Analytical Chemistry, Institute of Chemical Technology in Prague, Technická 3 5, 166 28 Prague 6, Czech Republic
    Spectrochim Acta A Mol Biomol Spectrosc 66:225-35. 2007
    ..The complex nature of CD bands assigned to both types of porphyrin aggregates indicated the occurrence of several chiral macrocyclic species dependently on pH value and chitosan concentration...
  4. doi request reprint pH-controlled self-assembling of meso-tetrakis(4-sulfonatophenyl)porphyrin-chitosan complexes
    Alla Synytsya
    Department of Analytical Chemistry, Institute of Chemical Technology, Prague 16628, Czech Republic
    Biomacromolecules 10:1067-76. 2009
    ..Based on structural inferences, self-assembling hierarchy models were proposed for both of the TPPS(4)-chitosan supramolecular complexes...
  5. ncbi request reprint Synthesis and biolocalization of water-soluble sapphyrins
    Vladimir Kral
    Department of Analytical Chemistry, Institute of Chemical Technology, Technicka 5, 166 28 Prague, Czech Republic
    J Med Chem 45:1073-8. 2002
    ..The concentrations of the water-soluble sapphyrins reported here, as well as a porphyrin control system, were determined as a function of time and tissue type...
  6. doi request reprint Modification of chitosan-methylcellulose composite films with meso-tetrakis(4-sulfonatophenyl)porphyrin
    Alla Synytsya
    Department of Analytical Chemistry, Institute of Chemical Technology in Prague, 166 28 Prague, The Czech Republic
    Biomacromolecules 13:489-98. 2012
    ..ECD measurements detected the presence of optically active porphyrin species bound to the films. SEM and AFM images confirmed that the porphyrin macrocycles caused structural changes on the film surface and within the film layer...
  7. ncbi request reprint Biolocalisation and photochemical properties of two novel macrocyclic photosensitisers: a spectroscopic study
    Alla Synytsya
    Department of Analytical Chemistry, Institute of Chemical Technology in Prague, Technicka 5, 166 28 Prague 6, Czech Republic
    J Photochem Photobiol B 74:73-84. 2004
    ..Raman spectroscopic study indicated that monomerised photosensitiser 2 effectively damaged BSA and calf thymus DNA after light excitation at the conditions of high excess of these macromolecules...
  8. ncbi request reprint Novel porphyrin conjugates with a potent photodynamic antitumor effect: differential efficacy of mono- and bis-beta-cyclodextrin derivatives in vitro and in vivo
    Jarmila Kralova
    Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague, Czech Republic
    Photochem Photobiol 82:432-8. 2006
    ..Thus, P(beta-CD)2 represents a new photosensitizing drug displaying fast and selective tumor uptake, strong antitumor activity and fast elimination from the body...
  9. ncbi request reprint The complexation of metal cations by D-galacturonic acid: a spectroscopic study
    Andriy Synytsya
    Department of Carbohydrate Chemistry and Technology, Institute of Chemical Technology, Technická 3 5, 166 28 Prague 6, Czech Republic
    Carbohydr Res 339:2391-405. 2004
    ..Possible ways of GalA coordination by metal cations of this study were proposed and discussed...
  10. doi request reprint Analysis of human blood plasma and hen egg white by chiroptical spectroscopic methods (ECD, VCD, ROA)
    Alla Synytsya
    Department of Analytical Chemistry, Institute of Chemical Technology Prague, Technicka 5, 166 28, Prague 6, Czech Republic
    Anal Bioanal Chem 405:5441-53. 2013
    ..The results obtained in this work demonstrate that the chiroptical methods used here can be applied to analyze not only pure protein solutions but also more complex systems, such as biological fluids...