K Smetana

Summary

Affiliation: Institute of Hematology and Blood Transfusion
Country: Czech Republic

Publications

  1. ncbi request reprint To the nucleolar bodies (nucleoli) in cells of the lymphocytic lineage in patients suffering from B - chronic lymphocytic leukemia
    K Smetana
    Institute of Hematology and Blood Transfusion, Prague, Czech Republic
    Neoplasma 57:495-500. 2010
  2. ncbi request reprint Galectin-7: will the lectin's activity establish clinical correlations in head and neck squamous cell and basal cell carcinomas?
    Z Cada
    Charles University in Prague, First Faculty of Medicine, Prague, Czech Republic
    Histol Histopathol 24:41-8. 2009
  3. doi request reprint Phenotypic characterization of human keratinocytes in coculture reveals differential effects of fibroblasts from benign fibrous histiocytoma (dermatofibroma) as compared to cells from its malignant form and to normal fibroblasts
    L Kideryová
    Charles University in Prague, 1st Faculty of Medicine, 1st Department of Internal Medicine, Prague, Czech Republic
    J Dermatol Sci 55:18-26. 2009
  4. ncbi request reprint Fusion of macrophages on an implant surface is associated with down-regulated expression of ligands for galectin-1 and -3 in the rat
    K Smetana
    Institute of Anatomy, 1st Faculty of Medicine, Charles University, Prague, Czech Republic
    Biomaterials 19:1799-805. 1998
  5. ncbi request reprint The 5-aminolaevulinic acid-based photodynamic effects on nuclei and nucleoli of HL-60 leukemic granulocytic precursors
    K Smetana
    Institute of Hematology and Blood Transfusion, Prague, Czech Republic
    J Photochem Photobiol B 59:80-6. 2000
  6. ncbi request reprint Differential regulation of galectin expression/reactivity during wound healing in porcine skin and in cultures of epidermal cells with functional impact on migration
    J Klima
    Institute of Animal Physiology and Genetics, Academy of Sciences of the Czech Republic, Prague, Czech Republic
    Physiol Res 58:873-84. 2009
  7. ncbi request reprint Comparative analysis of the nuclear presence of adhesion/growth-regulatory galectins and reactivity in the nuclei of interphasic and mitotic cells
    O Kodet
    Institute of Anatomy, First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic
    Folia Biol (Praha) 57:125-32. 2011
  8. ncbi request reprint Expression of galectin-3-reactive ligands in squamous cancer and normal epithelial cells as a marker of differentiation
    J Plzak
    Institute of Anatomy, First Faculty of Medicine, Charles University, Prague, Czech Republic
    Int J Oncol 19:59-64. 2001
  9. ncbi request reprint To the density and distribution of heterochromatin in differentiating, maturing and apoptotic cells represented by granulocytic, lymphocytic and erythrocytic precursors
    K Smetana
    Institute of Haematology and Blood Transfusion, Prague, Czech Republic
    Folia Biol (Praha) 54:8-11. 2008
  10. ncbi request reprint Immunohistochemical fingerprinting of the network of seven adhesion/growth-regulatory lectins in human skin and detection of distinct tumour-associated alterations
    Z Cada
    Charles University in Prague, First Faculty of Medicine Institute of Anatomy, Prague, Czech Republic
    Folia Biol (Praha) 55:145-52. 2009

Collaborators

Detail Information

Publications45

  1. ncbi request reprint To the nucleolar bodies (nucleoli) in cells of the lymphocytic lineage in patients suffering from B - chronic lymphocytic leukemia
    K Smetana
    Institute of Hematology and Blood Transfusion, Prague, Czech Republic
    Neoplasma 57:495-500. 2010
    ..Keywords: B-chronic lymphocytic leukemia; lymphocytes; nucleolar classes; size; nucleolar RNA image density -concentration...
  2. ncbi request reprint Galectin-7: will the lectin's activity establish clinical correlations in head and neck squamous cell and basal cell carcinomas?
    Z Cada
    Charles University in Prague, First Faculty of Medicine, Prague, Czech Republic
    Histol Histopathol 24:41-8. 2009
    ..Absence of Gal-7 expression was detected in basal cell carcinomas. These clinical data delineate Gal-7 influence on differentiation in vivo, without evidence for a role in dissemination reported for lymphoma...
  3. doi request reprint Phenotypic characterization of human keratinocytes in coculture reveals differential effects of fibroblasts from benign fibrous histiocytoma (dermatofibroma) as compared to cells from its malignant form and to normal fibroblasts
    L Kideryová
    Charles University in Prague, 1st Faculty of Medicine, 1st Department of Internal Medicine, Prague, Czech Republic
    J Dermatol Sci 55:18-26. 2009
    ..Benign and malignant fibrous histiocytoma present with a considerable difference concerning cellular organization in their vicinity...
  4. ncbi request reprint Fusion of macrophages on an implant surface is associated with down-regulated expression of ligands for galectin-1 and -3 in the rat
    K Smetana
    Institute of Anatomy, 1st Faculty of Medicine, Charles University, Prague, Czech Republic
    Biomaterials 19:1799-805. 1998
    ....
  5. ncbi request reprint The 5-aminolaevulinic acid-based photodynamic effects on nuclei and nucleoli of HL-60 leukemic granulocytic precursors
    K Smetana
    Institute of Hematology and Blood Transfusion, Prague, Czech Republic
    J Photochem Photobiol B 59:80-6. 2000
    ..On the other hand, a small subpopulation of cells was less sensitive or resistant to the ALA-based PDE since they did not show mentioned nuclear and nucleolar alterations...
  6. ncbi request reprint Differential regulation of galectin expression/reactivity during wound healing in porcine skin and in cultures of epidermal cells with functional impact on migration
    J Klima
    Institute of Animal Physiology and Genetics, Academy of Sciences of the Czech Republic, Prague, Czech Republic
    Physiol Res 58:873-84. 2009
    ..This report thus presents new information on endogenous lectins in wound healing and differential regulation among the three tested cases...
  7. ncbi request reprint Comparative analysis of the nuclear presence of adhesion/growth-regulatory galectins and reactivity in the nuclei of interphasic and mitotic cells
    O Kodet
    Institute of Anatomy, First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic
    Folia Biol (Praha) 57:125-32. 2011
    ..The extensive binding of labelled galectins-1 and -2 to mitotic cells (around chromosomes, in mitotic spindle and in bridge connecting both daughter cells) suggests their role during the cell division...
  8. ncbi request reprint Expression of galectin-3-reactive ligands in squamous cancer and normal epithelial cells as a marker of differentiation
    J Plzak
    Institute of Anatomy, First Faculty of Medicine, Charles University, Prague, Czech Republic
    Int J Oncol 19:59-64. 2001
    ....
  9. ncbi request reprint To the density and distribution of heterochromatin in differentiating, maturing and apoptotic cells represented by granulocytic, lymphocytic and erythrocytic precursors
    K Smetana
    Institute of Haematology and Blood Transfusion, Prague, Czech Republic
    Folia Biol (Praha) 54:8-11. 2008
    ..e. in "gene-rich nuclear regions", of differentiating and maturing progenitors of blood cells preceded that at the nuclear periphery...
  10. ncbi request reprint Immunohistochemical fingerprinting of the network of seven adhesion/growth-regulatory lectins in human skin and detection of distinct tumour-associated alterations
    Z Cada
    Charles University in Prague, First Faculty of Medicine Institute of Anatomy, Prague, Czech Republic
    Folia Biol (Praha) 55:145-52. 2009
    ....
  11. ncbi request reprint Coexpression of binding sites for A(B) histo-blood group trisaccharides with galectin-3 and Lag antigen in human Langerhans cells
    K Smetana
    Institute for Anatomy, 1st Faculty of Medicine, Charles University, Prague, Czech Republic
    J Leukoc Biol 66:644-9. 1999
    ..These results suggest that galectin-3 is present in Birbeck granules, where it retains reactivity for its glycoligands...
  12. doi request reprint Microscopic notes on the perinucleolar chromatin region in immature and mature human B-leukemia lymphocytes
    K Smetana
    Institute of Hematology and Blood Transfusion, Prague
    Neoplasma 60:284-9. 2013
    ..They might be associated with presumed special perinucleolar DNA loci, which according some previous studies were more expressed in malignant cells...
  13. doi request reprint Fibroblasts prepared from different types of malignant tumors stimulate expression of luminal marker keratin 8 in the EM-G3 breast cancer cell line
    B Dvorankova
    Institute of Anatomy, Charles University, Prague, Czech Republic
    Histochem Cell Biol 137:679-85. 2012
    ..Finally, a clear functional difference between normal and CAFs was demonstrated...
  14. ncbi request reprint Heterochromatin density (condensation) during cell differentiation and maturation using the human granulocytic lineage of chronic myeloid leukaemia as a convenient model
    K Smetana
    Institute of Haematology and Blood Transfusion, Prague, Czech Republic
    Folia Biol (Praha) 57:216-21. 2011
    ..From the methodological point of view, both, the cytochemical method for the DNA demonstration and the panoptic May-Grünwald-Giemsa staining, are convenient for computer-assisted chromatin densitometry at the single-cell level...
  15. ncbi request reprint A note on the decreased number and loss of fibrillar centres in nucleoli of apoptotic HL-60 leukaemic granulocytic precursors produced by 5-aminolaevulinic acid-based photodynamic treatment
    K Smetana
    Institute of Haematology and Blood Transfusion, Prague, Czech Republic
    Folia Biol (Praha) 50:15-20. 2004
    ..Some electron micrographs also indicated that fibrillar centres apparently migrated out from nucleolar bodies...
  16. ncbi request reprint On the nucleolar size and density in human early granulocytic progenitors, myeloblasts
    K Smetana
    Institute of Hematology and Blood Transfusion, U Nemocnice 1, Prague, Czech Republic
    Eur J Histochem 50:119-24. 2006
    ..In addition, karyometry combined with RNA cytochemistry still appears to be an useful tool to study nucleoli at the single cell level...
  17. ncbi request reprint A karyometric note on nucleoli in human early granulocytic precursors
    K Smetana
    Clinical Department, Institute of Haematology and Blood Transfusion, Prague, Czech Republic
    Folia Biol (Praha) 52:16-20. 2006
    ....
  18. ncbi request reprint The asymmetric distribution of interphasic silver-stained nucleolus organizer regions in human and rat proerythroblasts
    K Smetana
    Institute of Hematology and Blood Transfusion, Prague, Czech Republic
    Folia Biol (Praha) 45:243-6. 1999
    ..Cells in such stages, as described previously, were characterized by the presence of a limited number of single SSPs...
  19. ncbi request reprint Human galectin-2: nuclear presence in vitro and its modulation by quiescence/stress factors
    B Dvorankova
    Charles University, 1st Faculty of Medicine, Institute of Anatomy, Prague, Czech Republic
    Histol Histopathol 23:167-78. 2008
    ..That even closely related family members, here galectins-1 and -2, exhibit distinct intranuclear localization patterns gives ensuing research a clear direction...
  20. doi request reprint Phosphorylated human lectin galectin-3: analysis of ligand binding by histochemical monitoring of normal/malignant squamous epithelia and by isothermal titration calorimetry
    P Szabo
    1st Faculty of Medicine, Institute of Anatomy, Charles University, Prague, Czech Republic
    Anat Histol Embryol 38:68-75. 2009
    ..It underscores the value of using endogenous lectins as a histochemical tool. The documented approach has merit for applications beyond lectinology...
  21. ncbi request reprint Intranucleolar translocation of AgNORs in early granulocytic precursors in chronic myeloid leukaemia and K 562 cells
    K Smetana
    Institute of Haematology and Blood Transfusion, Prague, Czech Republic
    Folia Biol (Praha) 51:89-92. 2005
    ..However, more clinically oriented studies are required in this direction...
  22. ncbi request reprint Nucleoli in cells of the granulopoietic proliferating compartment in patients suffering from the refractory anemia of the myelodysplastic syndrome
    K Smetana
    Institute of Hematology and Blood Transfusion, Prague, Czech Republic
    Neoplasma 47:280-2. 2000
    ..In addition, the values of the nucleolar coefficient of myeloblasts in patients with RA of MDS were close to those in patients with acute myeloid leukemias...
  23. ncbi request reprint Nucleoli in human early erythroblasts (K2, K1, K1/2 cells)
    K Smetana
    Clinical Department, Institute of Hematology and Blood Transfusion, Prague, Czech Republic
    Folia Biol (Praha) 51:25-8. 2005
    ..More studies, however, are required in this direction...
  24. ncbi request reprint Attempts to induce melanosome degradation in vivo
    J Borovansky
    2nd Department of Medical Chemistry and Biochemistry, Charles University, Prague, Czech Republic
    Folia Biol (Praha) 45:47-52. 1999
    ..Considering the structure of melanins, redox mechanisms (analogous with the metabolism of polycyclic hydrocarbons (DePierre and Ernster, 1978)) seem to be more probably involved in pigment degradation than hydrolytic reactions...
  25. ncbi request reprint Postmitotic basal cells in squamous cell epithelia are identified with Dolichos biflorus agglutinin--functional consequences
    E Hrdlicková-Cela
    Charles University, 1st Faculty of Medicine, Institute of Anatomy, Prague, Czech Republic
    APMIS 109:714-20. 2001
    ..This process seems to be important for the migration of postmitotic cells from the basal to the suprabasal layers...
  26. ncbi request reprint Cells of porcine epidermis and corneal epithelium are not recognized by human natural anti-alpha-galactoside IgG
    E Hrdlicková-Cela
    Charles University, 1st Faculty of Medicine, Institute of Anatomy, Prague, Czech Republic
    Folia Biol (Praha) 47:200-5. 2001
    ..With respect to a potential clinical perspective, the given results facilitate consideration of the use of porcine epidermal cells in engineering of non-permanent wound covers to improve treatment...
  27. ncbi request reprint Detection of alpha(beta)-N-acetyl-D-galactosamine-binding sites in kidney--relation to Henoch-Schönlein-associated IgA nephropathy
    A Sediva
    Institute of Immunology, 2nd Faculty of Medicine, Charles University, Prague, Czech Republic
    Folia Biol (Praha) 45:147-50. 1999
    ....
  28. ncbi request reprint Incidence of nucleoli in erythroblasts in patients suffering from refractory anemia of myelodysplastic syndrome
    K Smetana
    Clinical Section, Institute of Hematology and Blood Transfusion, Prague, Czech Republic
    Eur J Haematol 63:332-6. 1999
    ..Thus in patients with RA of MDS both the abnormal loss of nucleoli and decreased number of nucleoli in erythroblasts apparently represent and reflect a further abnormality of disturbed erythropoiesis...
  29. ncbi request reprint Experimental lesion of medial frontal cortex mediates inhibition of expression of carbohydrate-binding sites in the spleen macrophages in rat
    K Smetana
    Institute of Anatomy, 1st Faculty of Medicine, Charles University, Prague, Czech Republic
    Folia Biol (Praha) 45:87-90. 1999
    ..These data intimate that distinct brain regions are involved in the control of the phenotype of macrophages in the central lymphoid organs by currently elusive biochemical mechanisms...
  30. ncbi request reprint Glycophenotype of psoriatic skin
    L Lacina
    Institute of Anatomy, 1st Faculty of Medicine, Charles University, Prague, Czech Republic
    Folia Biol (Praha) 52:10-5. 2006
    ..The enhanced expression of galectin-3/galectin-3-reactive glycoligands in dermal capillaries of psoriatic skin can be important for rearrangement of the capillary network and migration of inflammatory cells to psoriatic skin...
  31. ncbi request reprint Stromal fibroblasts from basal cell carcinoma affect phenotype of normal keratinocytes
    L Lacina
    Institute of Anatomy and Department of Dermatovenerology, First Faculty of Medicine and Centre of Cell Therapy and Tissue Repair, Second Faculty of Medicine Charles University, Prague, Czech Republic
    Br J Dermatol 156:819-29. 2007
    ..Epithelial-mesenchymal interactions are important not only to direct the course of prenatal development of skin and its appendages but also to influence the behaviour of transformed epithelial cells...
  32. ncbi request reprint The effect of a histone deacetylase inhibitor - valproic acid - on nucleoli in human leukaemic myeloblasts
    K Smetana
    Institute of Haematology and Blood Transfusion, Prague, Czech Republic
    Folia Biol (Praha) 56:201-5. 2010
    ....
  33. ncbi request reprint Influence of hydroxyapatite crystallinity on the growth of keratinocytes
    M Seydlova
    Charles University in Prague, Second Faculty of Medicine and Motol University Hospital, Department of Paediatric Stomatology, Prague, Czech Republic
    Prague Med Rep 109:142-8. 2008
    ..The worst proliferation of fibroblasts was found on the amorphous coating, whereas the adhesion was fully comparable with other surfaces. The level of keratinocyte differentiation was the same on both of the studied surfaces...
  34. ncbi request reprint A short note on micronucleoli in the course of terminal maturation of human erythroblasts
    K Smetana
    Clinical Department, Institute of Hematology and Blood Transfusion, Prague, Czech Republic
    Folia Biol (Praha) 47:14-7. 2001
    ..In addition, silver-stained micronucleoli--nucleolar remnants--were also noted in erythroblasts expelling the nucleus...
  35. ncbi request reprint The RNA content of nucleolar bodies is related to their size - a cytochemical study on human monocytes and lymphocytes in blood smears and blood cytospins
    K Smetana
    Institute of Haematology and Blood Transfusion, Prague, Czech Republic
    Folia Biol (Praha) 54:130-3. 2008
    ....
  36. ncbi request reprint Synthetic hydrogel capacity to induce formation of foreign-body giant multinucleate cells differs in vivo and in vitro
    K Smetana
    Charles University, 1st Faculty of Medicine, Institute of Anatomy, Prague, Czech Republic
    Folia Biol (Praha) 46:113-8. 2000
    ..They also indicate potential differences between granuloma formation induced by parasites and by foreign bodies...
  37. ncbi request reprint Heterochromatin condensation in central and peripheral nuclear regions of maturing lymphocytes in the peripheral blood of patients suffering from B chronic lymphocytic leukemia - a cytochemical study
    K Smetana
    Institute of Hematology and Blood Transfusion, Czech Republic
    Neoplasma 58:476-81. 2011
    ..Such phenomenon might represent the return to the cell cycle or a further type of maturation asynchrony that in leukemic cells is not exceptional...
  38. ncbi request reprint Satellite nucleoli in the megakaryocytic lineage of rats
    J Janoutová
    Institute of Histology and Embryology, Third Faculty of Medicine, Charles University, Prague, Czech Republic
    Physiol Res 50:113-7. 2001
    ..The decreased incidence of satellite nucleoli in naked megakaryocytic nuclei might reflect their disintegration in the terminal stages of the megakaryocytic development...
  39. ncbi request reprint Shifts of lymphoid and phagocytic cell populations during mild cold acclimation in hairless mice
    M Cervinkova
    Division of Immunology and Gnotobiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic
    Folia Microbiol (Praha) 43:481-2. 1998
  40. ncbi request reprint Effect of histone deacetylase inhibitors on the cell nucleus and nucleolus of leukemic myeloblasts in vitro - a cytochemical study
    K Smetana
    Institute of Haematology and Blood Transfusion, Prague, Czech Republic
    Acta Histochem 109:413-9. 2007
    ....
  41. ncbi request reprint Reduced phagocytic activity of polymorphonuclear leukocytes in alpha(1,3) fucosyltransferase VII-deficient mice
    J Bartunkova
    Institute of Immunology, 2nd Faculty of Medicine, Charles University, Prague, Czech Republic
    APMIS 108:409-16. 2000
    ..In conclusion, the lack of Fuc-TVII activity leads to several morphological and functional abnormalities without an impact on survival rate...
  42. ncbi request reprint Nucleoli in large (giant) bi- and multinucleate cells after apoptosis-inducing photodynamic treatment
    K Smetana
    Institute of Hematology and Blood Transfusion, Prague, Czech Republic
    Eur J Histochem 47:39-43. 2003
    ..These changes apparently reflected the decrease or cessation of nucleolar biosynthetic activities and resembled those which were previously observed in naturally maturing bone marrow megakaryocytes (Janoutová et al., 2001)...
  43. ncbi request reprint Nucleolar abnormalities--a defect of the nucleolar preribosome assembly--in ringed sideroblasts in refractory anaemia with ringed sideroblasts (RARS) of myelodysplastic syndrome (MDS). An electron microscopic study
    K Smetana
    Institute of Haematology and Blood Transfusion, Haematology Clinic, Institute of Medical Postgraduate Studies, Prague, Czech Republic
    Sb Lek 104:199-207. 2003
    ....
  44. ncbi request reprint Decrease of nuclear reactivity to growth-regulatory galectin-1 in senescent human keratinocytes and detection of non-uniform staining profile alterations upon prolonged culture for galectin-1 and -3
    M Chovanec
    First Faculty of Medicine, Institute of Anatomy, Charles University, Prague, Czech Republic
    Anat Histol Embryol 33:348-54. 2004
    ....
  45. ncbi request reprint Characteristic of two mouse bcr-abl-transformed cell lines: I. General properties of the cells
    E Sobotkova
    Department of Experimental Virology, Institute of Hematology and Blood Transfusion, Prague, Czech Republic
    Folia Biol (Praha) 51:12-8. 2005
    ..Moreover, 12B1, but not B210, induced tumours after subcutaneous or intraperitoneal inoculation...