Roman Prymula

Summary

Affiliation: Faculty of Military Health Sciences
Country: Czech Republic

Publications

  1. ncbi request reprint Clinical experience with DTPw-HBV and DTPw-HBV/Hib combination vaccines
    Roman Prymula
    University of Defense, Department of Epidemiology, Faculty of Military Health Science, Hradec Kralove, Czech Republic
    Expert Opin Biol Ther 8:503-13. 2008
  2. doi request reprint Effect of prophylactic paracetamol administration at time of vaccination on febrile reactions and antibody responses in children: two open-label, randomised controlled trials
    Roman Prymula
    Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic
    Lancet 374:1339-50. 2009
  3. doi request reprint 10-valent pneumococcal nontypeable Haemophilus influenzae PD conjugate vaccine: Synflorix
    Roman Prymula
    Department of Epidemiology, Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic
    Expert Rev Vaccines 8:1479-500. 2009
  4. doi request reprint Impact of the 10-valent pneumococcal non-typeable Haemophilus influenzae Protein D conjugate vaccine (PHiD-CV) on bacterial nasopharyngeal carriage
    Roman Prymula
    Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic
    Vaccine 29:1959-67. 2011
  5. doi request reprint Effect of vaccination with pneumococcal capsular polysaccharides conjugated to Haemophilus influenzae-derived protein D on nasopharyngeal carriage of Streptococcus pneumoniae and H. influenzae in children under 2 years of age
    Roman Prymula
    Department of Epidemiology, Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic
    Vaccine 28:71-8. 2009
  6. doi request reprint Central European Vaccination Advisory Group (CEVAG) guidance statement on recommendations for the introduction of HPV vaccines
    Roman Prymula
    University of Defense, Hradec Kralove, Czech Republic
    Eur J Pediatr 168:1031-5. 2009
  7. ncbi request reprint Pneumococcal capsular polysaccharides conjugated to protein D for prevention of acute otitis media caused by both Streptococcus pneumoniae and non-typable Haemophilus influenzae: a randomised double-blind efficacy study
    Roman Prymula
    Department of Epidemiology, Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic
    Lancet 367:740-8. 2006
  8. doi request reprint Safety of the 11-valent pneumococcal vaccine conjugated to non-typeable Haemophilus influenzae-derived protein D in the first 2 years of life and immunogenicity of the co-administered hexavalent diphtheria, tetanus, acellular pertussis, hepatitis B, inact
    Roman Prymula
    Department of Epidemiology, Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic
    Vaccine 26:4563-70. 2008
  9. doi request reprint Adult vaccination in 11 Central European countries - calendars are not just for children
    Roman Chlibek
    University of Defence, Trebesska 1575, 500 01 Hradec Kralove, Czech Republic
    Vaccine 30:1529-40. 2012
  10. doi request reprint Immunological memory and nasopharyngeal carriage in 4-year-old children previously primed and boosted with 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) with or without concomitant prophylactic paracetamo
    Roman Prymula
    University Hospital, Hradec Kralove, Czech Republic
    Vaccine 31:2080-8. 2013

Detail Information

Publications20

  1. ncbi request reprint Clinical experience with DTPw-HBV and DTPw-HBV/Hib combination vaccines
    Roman Prymula
    University of Defense, Department of Epidemiology, Faculty of Military Health Science, Hradec Kralove, Czech Republic
    Expert Opin Biol Ther 8:503-13. 2008
    ..In order to address growing demand for DTPw-based vaccines, GSK Biologicals have developed the Zilbrix range using a new DTPw antigen source and containing reduced quantities of polyribosylribitol phosphate [PRP]...
  2. doi request reprint Effect of prophylactic paracetamol administration at time of vaccination on febrile reactions and antibody responses in children: two open-label, randomised controlled trials
    Roman Prymula
    Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic
    Lancet 374:1339-50. 2009
    ..We assessed the effect of prophylactic administration of paracetamol at vaccination on infant febrile reaction rates and vaccine responses...
  3. doi request reprint 10-valent pneumococcal nontypeable Haemophilus influenzae PD conjugate vaccine: Synflorix
    Roman Prymula
    Department of Epidemiology, Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic
    Expert Rev Vaccines 8:1479-500. 2009
    ....
  4. doi request reprint Impact of the 10-valent pneumococcal non-typeable Haemophilus influenzae Protein D conjugate vaccine (PHiD-CV) on bacterial nasopharyngeal carriage
    Roman Prymula
    Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic
    Vaccine 29:1959-67. 2011
    ..Primary and booster vaccination with PHiD-CV reduced NPC of VT in the second year of life and tended to slightly increase that of NVT in line with previous experience with the 7-valent PCV...
  5. doi request reprint Effect of vaccination with pneumococcal capsular polysaccharides conjugated to Haemophilus influenzae-derived protein D on nasopharyngeal carriage of Streptococcus pneumoniae and H. influenzae in children under 2 years of age
    Roman Prymula
    Department of Epidemiology, Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic
    Vaccine 28:71-8. 2009
    ..influenzae was still reduced with 38.6% (95% CI: -6.3 to 64.6, ns). Reduction of acute otitis media (AOM) episodes preceded the impact on carriage. These data provide further support of the functional role of the protein D immunity...
  6. doi request reprint Central European Vaccination Advisory Group (CEVAG) guidance statement on recommendations for the introduction of HPV vaccines
    Roman Prymula
    University of Defense, Hradec Kralove, Czech Republic
    Eur J Pediatr 168:1031-5. 2009
    ....
  7. ncbi request reprint Pneumococcal capsular polysaccharides conjugated to protein D for prevention of acute otitis media caused by both Streptococcus pneumoniae and non-typable Haemophilus influenzae: a randomised double-blind efficacy study
    Roman Prymula
    Department of Epidemiology, Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic
    Lancet 367:740-8. 2006
    ..This study assessed the efficacy of a novel vaccine that contained polysaccharides from 11 different Streptococcus pneumoniae serotypes each conjugated to Haemophilus influenzae-derived protein D in prevention of acute otitis media...
  8. doi request reprint Safety of the 11-valent pneumococcal vaccine conjugated to non-typeable Haemophilus influenzae-derived protein D in the first 2 years of life and immunogenicity of the co-administered hexavalent diphtheria, tetanus, acellular pertussis, hepatitis B, inact
    Roman Prymula
    Department of Epidemiology, Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic
    Vaccine 26:4563-70. 2008
    ....
  9. doi request reprint Adult vaccination in 11 Central European countries - calendars are not just for children
    Roman Chlibek
    University of Defence, Trebesska 1575, 500 01 Hradec Kralove, Czech Republic
    Vaccine 30:1529-40. 2012
    ..This calendar could be modified to meet the priorities of individual countries...
  10. doi request reprint Immunological memory and nasopharyngeal carriage in 4-year-old children previously primed and boosted with 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) with or without concomitant prophylactic paracetamo
    Roman Prymula
    University Hospital, Hradec Kralove, Czech Republic
    Vaccine 31:2080-8. 2013
    ..This study further evaluated the effect of PP on antibody persistence, immunological memory and nasopharyngeal carriage (NPC)...
  11. ncbi request reprint The immunogenicity and reactogenicity of a new DTPw-HBV vaccine as a primary and booster vaccination course in healthy infants
    Roman Prymula
    Department of Epidemiology, Faculty of Military Health Sciences, University of Defense, Hradec Kralove, Czech Republic
    Hum Vaccin 3:121-6. 2007
    ..In conclusion, within the framework of this study the immunogenicity and safety profiles of GSK Biologicals' new DTPw-HBV vaccine when used for primary and booster vaccination were acceptable...
  12. doi request reprint Central European Vaccination Advisory Group (CEVAG) guidance statement on recommendations for 2009 pandemic influenza A(H1N1) vaccination
    Roman Chlibek
    Faculty of Military Health Sciences, University of Defense, Trebesska 1575, 500 01 Hradec Kralove, Czech Republic
    Vaccine 28:3758-66. 2010
    ..CEVAG recommends vaccination of all health-care workers, pregnant women, children > or = 6 months and <2 years of age and people with chronic medical conditions as a first priority...
  13. ncbi request reprint [Present view of conjugated pneumococcus vaccines]
    Roman Prymula
    Faculty of Military Health Sciences, University of Defence of Hradec Králové, Czech Republic
    Klin Mikrobiol Infekc Lek 12:98-102. 2006
    ..New candidate 9-valent vaccine proved significant reduction in overall morbidity in Gambia and 11-valent vaccine confirmed improved effect on acute otitis media...
  14. doi request reprint Protection against varicella with two doses of combined measles-mumps-rubella-varicella vaccine versus one dose of monovalent varicella vaccine: a multicentre, observer-blind, randomised, controlled trial
    Roman Prymula
    University Hospital, Hradec Kralove, Czech Republic
    Lancet 383:1313-24. 2014
    ..We assessed protection against varicella in naive children administered one dose of varicella vaccine or two doses of MMRV...
  15. ncbi request reprint Anthrax vaccines
    Miroslav Splino
    Department of Epidemiology, Military Medical Academy, Hradec Kralove, Czech Republic
    Ann Saudi Med 25:143-9. 2005
    ..Serious adverse reactions occur in about 1% of vaccinations. New second-generation vaccines in current research programs include recombinant live vaccines and recombinant sub-unit vaccines...
  16. doi request reprint A repeated syphilis infection imported from Thailand in an HIV positive couple of men-who-have-sex-with-men in Czech Republic
    Miloslav Salavec
    Department of Dermatovenerology, Charles University Medical School and Faculty Hospital, Sokolska 581, Hradec Kralove, Czech Republic
    Travel Med Infect Dis 12:84-7. 2014
    ..Such cases can become foci for dissemination of once locally rare infections and present a danger for the community. ..
  17. doi request reprint Antibody persistence after two vaccinations with either FSME-IMMUN® Junior or ENCEPUR® Children followed by third vaccination with FSME-IMMUN® Junior
    Roman Prymula
    University Hospital Hradec Kralove, Hradec Kralove, Czech Republic
    Hum Vaccin Immunother 8:736-42. 2012
    ....
  18. doi request reprint Acceptance and opinions of Intanza/IDflu intradermal influenza vaccine in the Czech Republic and Turkey
    Roman Prymula
    University Hospital, Hradec Kralove, Czech Republic
    Adv Ther 29:41-52. 2012
    ....
  19. ncbi request reprint Kinetics of the immune response following pneumococcal PD conjugate vaccination
    Lode Schuerman
    GlaxoSmithKline Biologicals, Rixensart, Belgium
    Vaccine 25:1953-61. 2007
    ....
  20. ncbi request reprint ELISA IgG concentrations and opsonophagocytic activity following pneumococcal protein D conjugate vaccination and relationship to efficacy against acute otitis media
    Lode Schuerman
    GlaxoSmithKline Biologicals, Rixensart, Belgium
    Vaccine 25:1962-8. 2007
    ..We conclude that serotype-specific OPA GMTs are an important endpoint to consider for evaluation of pneumococcal conjugate vaccines with respect to the protective efficacy against AOM (Study ID: 347414/NCT00119743)...