M Zamecnik

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..The lesion strongly simulated invasive carcinomas, such as adenosquamous carcinoma and adenoid basal carcinoma (epithelioma) of the cervix...

..The course of disease was indolent. Low-grade müllerian carcinosarcoma is to be distinguished from other biphasic müllerian tumors...

..Therefore, a collision of GIST and gastritis cystica profunda is suggested in the histogenesis of the lesion...

..It further expands the spectrum of possible differentiations in this polyphenotypic neoplasm...

..Ultrastructural study confirmed the endothelial nature of these cells. The results indicate that pseudoangiomatous SCL is truly angiomatous and should be termed as such. It could represent a sex steroid hormone-dependent lesion...

..The authors discuss a phenotypical similarity of the lesion with GI schwannoma as well as the possible existence of GI-type schwannoma outside the tubal GI tract...

..Group of tumors of specialized gonadal stroma is not discussed as it represents particular area and thus requires a separated review article...

..DFSP should be included in the differential diagnosis of EMA-positive spindle cell lesions of superficial soft tissue and skin...

..In surgical pathology practice, a finding of intratumoral axons and positivity for claudin-1 and especially for EMA should not preclude diagnosis of GIS...

..The tumor cells were positive for alpha-inhibin, CD99, actin, and negative for desmin, S100 protein, and epithelial markers. This type of ovarian stromal tumor may represent a calcifying stage of SST...

..The case represents further example of the somatic cell-derived tumor with focal germ cell-type differentiation and the first report of YST differentiation in Krukenberg tumor...

..The knowledge of occasional EMA positivity in DFSP is needed for a differential diagnosis between DFSP and other EMA+ soft tissue lesions...

..The presence of giant rosettes in fibrosarcomatous areas of dermatofibrosarcoma protuberans suggests a possible histogenetic relationship between fibrosarcomatous areas of DFSP and hyalinizing spindle cell tumor with giant rosettes...

..This association was suggestive of emperipolesis. The unusual clinicopathologic features caused some diagnostic difficulty...

..Immunohistochemical and ultrastructural findings support the conclusion that the progenitor cell displays myofibroblastic and fibroblastic features, with a capacity for smooth muscle differentiation...

..No signs of neurosecretory granules were present at ultrastructural level. None of the lesions recurred and none metastasized over a mean follow-up of 8.1 years...

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..All patients were women, whose ages ranged from 22 to 65 years (median, 32 years)...

..We interpreted the lesions as hybrid tumors with features of schwannoma and retiform perineurioma...

..This is, however, not the case and the distinction of teratoma from dermoid cyst must be based on other morphological findings...

..Our results are similar to those previously described in other studies of colonic changes after the NaP application. It reflects probably a similarity in composition of used NaP solutions...

..Our case shows the difficulties in the diagnosis of this lesion and confirms a low aggressiveness that was observed in all 10 cases described to date...

..It shows that extensive sampling/histological search may be needed for recognition of a minor component in a dedifferentiated tumor...

..In the GEJ of 5 autopsy cases of children with spastic quadriplegia (age range 7-10 years) CM in a short segment (0.5-3 mm in length), probably of metaplastic origin was identified, showing chronic inactive inflammation...

..The lesion should be distinguished particularly from mucocele-like lesions of the breast by the location, nodular arrangement, absence of accompanying ductal hyperplasia and staining properties of the mucous substances...

..Expression of p53 in SSAs was minimal. SSAs have malignant potential comparable with conventional adenomas and for this reason they must be distinguished from HPs...

..In contrast to gastrointestinal stromal tumors, genetically no substitution, deletion, or insertion occurred in c-kit exon 11 in all analyzed samples. Likewise, no deletion or insertion in part of c-kit exon 9 was observed...

..A causal role for HPV in hidradenoma papilliferum cannot be confirmed from our results, as the detection rate is too low. The exact role of the HPV in etiology and pathogenesis of this neoplasm has yet to be determined...

..It further indicates, along with finding of associated CIN, a role of oncogenic HPV in pathogenesis of ABE...

..This observation gives further evidence that this entity is a peripheral nerve sheath tumor and is unrelated to melanocytic neoplasms...

..The histologic and immunohistochemical findings in the present case support strongly the metaplastic origin of mullerianosis...