Josef Zamecnik

Summary

Affiliation: Charles University
Country: Czech Republic

Publications

  1. ncbi request reprint [Neuropathology of refractory epilepsy: the structural basis and mechanisms of epileptogenesis]
    J Zamecnik
    Ustav patologie a molekulární medicíny, Praha
    Cesk Patol 48:76-82. 2012
  2. pmc Resistin in idiopathic inflammatory myopathies
    Maria Filková
    Institute of Rheumatology, Department of Experimental Rheumatology of the 1st Faculty of Medicine, Charles University in Prague, Na Slupi 4, Prague 2, 128 50, Czech Republic
    Arthritis Res Ther 14:R111. 2012
  3. ncbi request reprint [Pseudotumors of the central nervous system]
    J Zamecnik
    Ústav patologie a molekulární medicíny 2, LF UK a FN Motol, Praha
    Cesk Patol 48:184-9. 2012
  4. doi request reprint The extracellular matrix and diffusion barriers in focal cortical dysplasias
    Josef Zamecnik
    Department of Pathology and Molecular Medicine, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, V Uvalu 84, 150 06 Prague, Czech Republic
    Eur J Neurosci 36:2017-24. 2012
  5. ncbi request reprint Value of thyroid transcription factor-1 and surfactant apoprotein A in the differential diagnosis of pulmonary carcinomas: a study of 109 cases
    Josef Zamecnik
    Department of Pathology, Charles University, 2nd Medical School, V Uvalu 84, 150 06 Prague, Czech Republic
    Virchows Arch 440:353-61. 2002
  6. ncbi request reprint Muscle lymphocytic infiltrates in thymoma-associated myasthenia gravis are phenotypically different from those in polymyositis
    Josef Zamecnik
    Department of Pathology and Molecular Medicine, Charles University, 2nd Medical Faculty and Faculty Hospital Motol, V Uvalu 84, 150 06 Prague, Czech Republic
    Neuromuscul Disord 17:935-42. 2007
  7. ncbi request reprint [Neuropathology of the glioneuronal lesions of the brain associated with pharmacoresistant epilepsy]
    J Zamecnik
    Ustav patologie a molekulární medicíny, 2 LF UK a FN Motol, Praha
    Cesk Patol 43:79-85. 2007
  8. doi request reprint Atrophy of type II fibres in myasthenia gravis muscle in thymectomized patients: steroid-induced change with prognostic impact
    Josef Zamecnik
    Department of Pathology and Molecular Medicine, Charles University Prague, 2nd Medical Faculty and University Hospital Motol, Prague, Czech Republic
    J Cell Mol Med 13:2008-18. 2009
  9. ncbi request reprint Immunolocalization of protein-bound 3-nitrotyrosine in inflammatory myopathies
    J Zamecnik
    Department of Pathology and Molecular Medicine, Charles University, 2nd Medical Faculty and University Hospital Motol, Prague, Czech Republic
    Cesk Patol 47:62-5. 2011
  10. ncbi request reprint Densities of parvalbumin-immunoreactive neurons in non-malformed hippocampal sclerosis-temporal neocortex and in cortical dysplasias
    J Zamecnik
    Department of Pathology and Molecular Medicine, Charles University, 2nd Medical Faculty, V Uvalu 84, 150 06 Prague, Czech Republic
    Brain Res Bull 68:474-81. 2006

Collaborators

Detail Information

Publications33

  1. ncbi request reprint [Neuropathology of refractory epilepsy: the structural basis and mechanisms of epileptogenesis]
    J Zamecnik
    Ustav patologie a molekulární medicíny, Praha
    Cesk Patol 48:76-82. 2012
    ..In addition to the diagnostics and classification of the lesions, the text provides a summary of current knowledge about the pathogenesis and mechanisms, by which they contribute to the genesis and spread of epilepsy...
  2. pmc Resistin in idiopathic inflammatory myopathies
    Maria Filková
    Institute of Rheumatology, Department of Experimental Rheumatology of the 1st Faculty of Medicine, Charles University in Prague, Na Slupi 4, Prague 2, 128 50, Czech Republic
    Arthritis Res Ther 14:R111. 2012
    ....
  3. ncbi request reprint [Pseudotumors of the central nervous system]
    J Zamecnik
    Ústav patologie a molekulární medicíny 2, LF UK a FN Motol, Praha
    Cesk Patol 48:184-9. 2012
    ..To avoid a diagnostic error, pathologists have to rely on careful microscopic analysis along with its correlation with clinical data and neuroradiological findings...
  4. doi request reprint The extracellular matrix and diffusion barriers in focal cortical dysplasias
    Josef Zamecnik
    Department of Pathology and Molecular Medicine, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, V Uvalu 84, 150 06 Prague, Czech Republic
    Eur J Neurosci 36:2017-24. 2012
    ..Thus, the changed ECM composition and altered ECS diffusion properties might represent additional factors contributing to epileptogenicity in FCD...
  5. ncbi request reprint Value of thyroid transcription factor-1 and surfactant apoprotein A in the differential diagnosis of pulmonary carcinomas: a study of 109 cases
    Josef Zamecnik
    Department of Pathology, Charles University, 2nd Medical School, V Uvalu 84, 150 06 Prague, Czech Republic
    Virchows Arch 440:353-61. 2002
    ..The combination of anti-TTF-1 with anti-SP-A does not increase the diagnostic usefulness of TTF-1 alone. Because of its diagnostic utility TTF-1 should be added to a panel of antibodies used for assessing tumors of unknown origin...
  6. ncbi request reprint Muscle lymphocytic infiltrates in thymoma-associated myasthenia gravis are phenotypically different from those in polymyositis
    Josef Zamecnik
    Department of Pathology and Molecular Medicine, Charles University, 2nd Medical Faculty and Faculty Hospital Motol, V Uvalu 84, 150 06 Prague, Czech Republic
    Neuromuscul Disord 17:935-42. 2007
    ..The finding of CD8+CD45RA+ lymphocytes in muscle may signify an underlying thymoma and should not be misdiagnosed as polymyositis...
  7. ncbi request reprint [Neuropathology of the glioneuronal lesions of the brain associated with pharmacoresistant epilepsy]
    J Zamecnik
    Ustav patologie a molekulární medicíny, 2 LF UK a FN Motol, Praha
    Cesk Patol 43:79-85. 2007
    ..The results of those studies are discussed in the review as well...
  8. doi request reprint Atrophy of type II fibres in myasthenia gravis muscle in thymectomized patients: steroid-induced change with prognostic impact
    Josef Zamecnik
    Department of Pathology and Molecular Medicine, Charles University Prague, 2nd Medical Faculty and University Hospital Motol, Prague, Czech Republic
    J Cell Mol Med 13:2008-18. 2009
    ..Therefore, the steroid-induced atrophy of type II fibres in MG muscle might be considered to be an unfavourable prognostic factor...
  9. ncbi request reprint Immunolocalization of protein-bound 3-nitrotyrosine in inflammatory myopathies
    J Zamecnik
    Department of Pathology and Molecular Medicine, Charles University, 2nd Medical Faculty and University Hospital Motol, Prague, Czech Republic
    Cesk Patol 47:62-5. 2011
    ..Despite the pathogenetic significance, the 3NT immunohistochemistry is of low diagnostic value for the differential diagnosis of IIM in muscle biopsy...
  10. ncbi request reprint Densities of parvalbumin-immunoreactive neurons in non-malformed hippocampal sclerosis-temporal neocortex and in cortical dysplasias
    J Zamecnik
    Department of Pathology and Molecular Medicine, Charles University, 2nd Medical Faculty, V Uvalu 84, 150 06 Prague, Czech Republic
    Brain Res Bull 68:474-81. 2006
    ....
  11. ncbi request reprint The extracellular space and matrix of gliomas
    Josef Zamecnik
    Department of Pathology and Molecular Medicine, Charles University, University Hospital Motol, 150 06 Prague, Czech Republic
    Acta Neuropathol 110:435-42. 2005
    ....
  12. ncbi request reprint Paraneoplastic opsoclonus-myoclonus syndrome associated with malignant fibrous histiocytoma: neuropathological findings
    J Zamecnik
    Department of Pathology and Molecular Medicine, Charles University, 2nd Medical Faculty, Prague
    Cesk Patol 40:63-7. 2004
    ....
  13. ncbi request reprint Distribution of the extracellular matrix glycoproteins in ependymomas--an immunohistochemical study with follow-up analysis
    J Zamecnik
    Department of Pathology and Molecular Medicine, Charles University, 2nd Faculty of Medicine, 15006 Prague, Czech Republic
    Neoplasma 51:214-22. 2004
    ..An abundant production of some ECM glycoproteins (tenascin and vitronectin) is present in a proportion of ependymomas and its immunohistochemical detection is of prognostic relevance...
  14. pmc Expression of thyroid transcription factor 1 in primary brain tumours
    J Zamecnik
    Department of Pathology and Molecular Medicine, Charles University, Second Medical Faculty, 150 06 Prague, Czech Republic
    J Clin Pathol 57:1111-3. 2004
    ..Recently, TTF-1 expression was also observed in certain areas of postnatal brain...
  15. ncbi request reprint Pediatric intracranial ependymomas: prognostic relevance of histological, immunohistochemical, and flow cytometric factors
    Josef Zamecnik
    Department of Pathology and Molecular Medicine, Charles University, 2nd Medical School, Prague, Czech Republic
    Mod Pathol 16:980-91. 2003
    ..Foci of hypercellularity should be specifically looked for in ependymomas for assessing the immunohistochemical studies...
  16. doi request reprint 1H MR spectroscopy in histopathological subgroups of mesial temporal lobe epilepsy
    Milan Hajek
    MR Unit, Department of Diagnostic and Interventional Radiology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
    Eur Radiol 19:400-8. 2009
    ..Subjects with non-lateralized (1)H MRS abnormalities did not have a worse postoperative seizure outcome. We found no significant impact of contralateral (1)H MRS abnormality on post-surgical seizure outcome...
  17. ncbi request reprint Diffusion parameters of the extracellular space in human gliomas
    Lydia Vargova
    Department of Neuroscience, Charles University, Second Medical Faculty, Prague, Czech Republic
    Glia 42:77-88. 2003
    ..Tumor malignancy grade strongly corresponds to an increase in ECS volume, which is accompanied by a change in ECS structure manifested by an increase in diffusion barriers for small molecules...
  18. doi request reprint SISCOM and FDG-PET in patients with non-lesional extratemporal epilepsy: correlation with intracranial EEG, histology, and seizure outcome
    Martin Kudr
    Department of Pediatric Neurology, Charles University, 2nd Faculty of Medicine, University Hospital Motol, Czech Republic
    Epileptic Disord 15:3-13. 2013
    ....
  19. ncbi request reprint (1)H MR spectroscopic imaging in patients with MRI-negative extratemporal epilepsy: correlation with ictal onset zone and histopathology
    Pavel Krsek
    Department of Pediatric Neurology, Second Medical School, Motol Hospital, Charles University, Prague, Czech Republic
    Eur Radiol 17:2126-35. 2007
    ..1)H MRS could be more sensitive for the detection of discrete malformations of cortical development than conventional MRI. It is valuable in the presurgical evaluation of patients without MRI-apparent lesions...
  20. doi request reprint Clinical characteristics in patients with hippocampal sclerosis with or without cortical dysplasia
    Petr Marusic
    Neurology Department, Charles University, 2nd Faculty of Medicine, Motol Hospital, Praha, Czech Republic
    Epileptic Disord 9:S75-82. 2007
    ..The aim of the study was to review clinical variables of MTLE/HS patients in order to distinguish preoperatively patients with associated microscopic cortical dysplasia in the temporal pole...
  21. doi request reprint Frontal lobe epilepsy with atypical seizure semiology resembling shuddering attacks or wet dog shake seizures
    Alena Jahodova
    Department of Pediatric Neurology, Motol Epilepsy Centre, Charles University, 2nd Medical School, Motol Hospital, Prague, Czech Republic
    Epileptic Disord 14:69-75. 2012
    ..Focal cortical dysplasia type Ib was histologically confirmed and the patient has been seizure-free for the three years following resection. [Published with video sequences]...
  22. ncbi request reprint Inflammatory myopathy associated with statins: report of three cases
    Klara Kuncova
    Department of Pathology and Molecular Medicine, Second Medical Faculty and University Hospital Motol, Charles University, Prague 5, Czech Republic
    Mod Rheumatol 24:366-71. 2014
    ..Moreover, multiple mitochondrial DNA deletions were found in two of them. The ability of statins to induce an immune-mediated response and their interactions with mitochondrial metabolism pathways are discussed...
  23. doi request reprint Immunohistochemical prognostic markers in intracranial ependymomas: systematic review and meta-analysis
    Klara Kuncova
    2nd Medical School and University Hospital Motol, Department of Pathology and Molecular Medicine, Charles University, Prague, Czech Republic
    Pathol Oncol Res 15:605-14. 2009
    ..We encourage to search for new, useful markers, as well as to standardize lab-techniques and data interpretation algorithms across laboratories in order to increase data compatibility...
  24. ncbi request reprint Successful epilepsy surgery with a resection contralateral to a suspected epileptogenic lesion
    Pavel Krsek
    Department of Pediatric Neurology, Charles University, Second Medical School, Motol Hospital, Prague, Czech Republic
    Epileptic Disord 9:82-9. 2007
    ..The contralateral lesion was reassessed as nonspecific enlargement of perivascular spaces. The patient has been seizure-free for more than two years.[Published with video sequences]...
  25. doi request reprint The metastasis promoting protein S100A4 is increased in idiopathic inflammatory myopathies
    Lucie Andrés Cerezo
    Department of Rheumatology of the First Faculty of Medicine, Institute of Rheumatology, Charles University, Na Slupi 4, 12850 Prague 2, Czech Republic
    Rheumatology (Oxford) 50:1766-72. 2011
    ..The aim of this study was to investigate the expression and possible role of S100A4 in idiopathic inflammatory myopathies...
  26. doi request reprint p16(INK4a) immunoprofiles of squamous lesions of the uterine cervix-implications for the reclassification of atypical immature squamous metaplasia
    Petr Skapa
    Department of Pathology and Molecular Medicine, Charles University, 2nd Medical School, University Hospital Motol, V Uvalu 84, 150 06, Prague 5, Czech Republic
    Pathol Oncol Res 19:707-14. 2013
    ..The efficacy of CK 17 immunohistochemistry seems to be controversial for these purposes. ..
  27. ncbi request reprint Life-saving epilepsy surgery for status epilepticus caused by cortical dysplasia
    Pavel Krsek
    Department of Paediatric Neurology, Charles University, 2nd Medical School, Motol University Hospital, Prague, Czech Republic
    Epileptic Disord 4:203-8. 2002
    ..The aim of the report is to encourage considering surgery in selected patients suffering from medically intractable SE early in life...
  28. ncbi request reprint Magnetic resonance tracking of human CD34+ progenitor cells separated by means of immunomagnetic selection and transplanted into injured rat brain
    Pavla Jendelova
    Institute of Experimental Medicine ASCR, Prague, Czech Republic
    Cell Transplant 14:173-82. 2005
    ..The fact that microbeads coated with different commercially available antibodies can bind to specific cell types opens extensive possibilities for cell tracking in vivo...
  29. ncbi request reprint Analysis of histopathologic and molecular pathologic findings in Czech LGMD2A patients
    Marketa Hermanova
    Department of Pathology, University Hospital Brno, Jihlavska 20, 625 00, Brno, Czech Republic
    Muscle Nerve 33:424-32. 2006
    ....
  30. ncbi request reprint Human papillomavirus (HPV) profiles of vulvar lesions: possible implications for the classification of vulvar squamous cell carcinoma precursors and for the efficacy of prophylactic HPV vaccination
    Petr Skapa
    Department of Pathology and Molecular Medicine, Charles University, 2nd Medical School, Faculty Hospital Motol, Prague, Czech Republic
    Am J Surg Pathol 31:1834-43. 2007
    ....
  31. ncbi request reprint Diagnostic immunohistology of muscle diseases
    Hannes Vogel
    Department of Pathology, Stanford University School of Medicine, Palo Alto, CA 94305, USA
    J Neuropathol Exp Neurol 64:181-93. 2005
    ..Three broad categories of muscle diseases will be characterized in terms of diagnostic antibodies in current use: dystrophic, congenital/structural, and inflammatory myopathies...
  32. ncbi request reprint Unexpected sudden death caused by medullary brain lesions involves all age groups and may include 'sudden infant death syndrome' as a subset
    J Howard Jaster
    Acta Neuropathol 109:552-3. 2005
  33. doi request reprint Carbonic anhydrase IX expression in clear cell renal cell carcinomas negatively correlates with the proportion of the granular cell component
    Petr Skapa
    J Clin Oncol 26:3809-11; author reply 3811-2. 2008