M Vokurka

Summary

Affiliation: Charles University
Country: Czech Republic

Publications

  1. ncbi request reprint [Hepcidin--a peptide regulating the quantity and distribution of iron in the body in healthy and disease states]
    M Vokurka
    Ustav patologické fyziologie 1 LF UK, Praha
    Cas Lek Cesk 142:465-9. 2003
  2. ncbi request reprint Hepcidin mRNA levels in mouse liver respond to inhibition of erythropoiesis
    M Vokurka
    Institute of Pathophysiology, First Faculty of Medicine, Charles University, Prague, Czech Republic
    Physiol Res 55:667-74. 2006
  3. ncbi request reprint Hepcidin expression in the liver of mice with implanted tumour reacts to iron deficiency, inflammation and erythropoietin administration
    M Vokurka
    Institute of Pathophysiology and Centre for Experimental Haematology, First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic
    Folia Biol (Praha) 57:248-54. 2011
  4. ncbi request reprint Hepcidin downregulation by repeated bleeding is not mediated by soluble hemojuvelin
    J Krijt
    Institute of Pathophysiology and Center of Experimental Hematology, Charles University in Prague, First Faculty of Medicine, Prague, Czech Republic
    Physiol Res 59:53-9. 2010
  5. ncbi request reprint Effect of lipopolysaccharide and bleeding on the expression of intestinal proteins involved in iron and haem transport
    J Krijt
    Institute of Pathophysiology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic
    Folia Biol (Praha) 52:1-5. 2006
  6. ncbi request reprint Decreased hemojuvelin protein levels in mask mice lacking matriptase-2-dependent proteolytic activity
    J Frýdlová
    Institute of Pathophysiology, First Faculty of Medicine, Charles University, Prague, Czech Republic
    Physiol Res 62:405-11. 2013
  7. ncbi request reprint Plasma hepcidin correlates positively with interleukin-6 in patients undergoing pulmonary endarterectomy
    P Maruna
    Institute of Pathological Physiology, First Faculty of Medicine, Charles University in Prague, Czech Republic
    Physiol Res 60:493-502. 2011
  8. ncbi request reprint Hepcidin expression in adipose tissue increases during cardiac surgery
    M Vokurka
    Institute of Pathological Physiology, Center of Experimental Hematology, First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic
    Physiol Res 59:393-400. 2010
  9. ncbi request reprint Herbicide-induced experimental variegate porphyria in mice: tissue porphyrinogen accumulation and response to porphyrogenic drugs
    J Krijt
    Institute of Pathophysiology, First Faculty of Medicine, Charles University, Prague, Czech Republic
    Can J Physiol Pharmacol 75:1181-7. 1997

Detail Information

Publications9

  1. ncbi request reprint [Hepcidin--a peptide regulating the quantity and distribution of iron in the body in healthy and disease states]
    M Vokurka
    Ustav patologické fyziologie 1 LF UK, Praha
    Cas Lek Cesk 142:465-9. 2003
    ..Hepcidin is not only the physiological regulator of iron kinetics but is supposed to be a part of the pathogenetic mechanism of anaemia accompanying chronic diseases and its relationship to the hereditary hemochromatosis is also studied...
  2. ncbi request reprint Hepcidin mRNA levels in mouse liver respond to inhibition of erythropoiesis
    M Vokurka
    Institute of Pathophysiology, First Faculty of Medicine, Charles University, Prague, Czech Republic
    Physiol Res 55:667-74. 2006
    ..We propose that hepcidin is exclusively sensitive to iron utilization for erythropoiesis and hepatocyte iron balance, and these changes are not sensed by other genes involved in the control of iron metabolism in the liver...
  3. ncbi request reprint Hepcidin expression in the liver of mice with implanted tumour reacts to iron deficiency, inflammation and erythropoietin administration
    M Vokurka
    Institute of Pathophysiology and Centre for Experimental Haematology, First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic
    Folia Biol (Praha) 57:248-54. 2011
    ....
  4. ncbi request reprint Hepcidin downregulation by repeated bleeding is not mediated by soluble hemojuvelin
    J Krijt
    Institute of Pathophysiology and Center of Experimental Hematology, Charles University in Prague, First Faculty of Medicine, Prague, Czech Republic
    Physiol Res 59:53-9. 2010
    ..In addition, the presented data suggest that, under in vivo conditions, tissue hypoxia does not transcriptionally regulate the activity of furin or TMPRSS6 proteases...
  5. ncbi request reprint Effect of lipopolysaccharide and bleeding on the expression of intestinal proteins involved in iron and haem transport
    J Krijt
    Institute of Pathophysiology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic
    Folia Biol (Praha) 52:1-5. 2006
    ..A decrease in circulating hepcidin increases the expression of proteins participating in non-haem iron uptake, but has no significant effect on Hcp1 mRNA content...
  6. ncbi request reprint Decreased hemojuvelin protein levels in mask mice lacking matriptase-2-dependent proteolytic activity
    J Frýdlová
    Institute of Pathophysiology, First Faculty of Medicine, Charles University, Prague, Czech Republic
    Physiol Res 62:405-11. 2013
    ..The regulation of transferrin receptor 2 protein levels by transferrin saturation was not affected in mask mice. How the loss of matriptase-2 proteolytic activity leads to decreased hemojuvelin protein levels is at present unclear. ..
  7. ncbi request reprint Plasma hepcidin correlates positively with interleukin-6 in patients undergoing pulmonary endarterectomy
    P Maruna
    Institute of Pathological Physiology, First Faculty of Medicine, Charles University in Prague, Czech Republic
    Physiol Res 60:493-502. 2011
    ..Hepcidin increase was related to IL-6 concentrations and to the duration of surgical procedure. Our clinical findings are in conformity with recent experimental studies defining hepcidin as a type II acute-phase protein...
  8. ncbi request reprint Hepcidin expression in adipose tissue increases during cardiac surgery
    M Vokurka
    Institute of Pathological Physiology, Center of Experimental Hematology, First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic
    Physiol Res 59:393-400. 2010
    ..We suggest that acute inflammatory changes could affect the regulation of hepcidin expression in subcutaneous adipose tissue and thus possibly contribute to inflammation-induced systemic changes of iron metabolism...
  9. ncbi request reprint Herbicide-induced experimental variegate porphyria in mice: tissue porphyrinogen accumulation and response to porphyrogenic drugs
    J Krijt
    Institute of Pathophysiology, First Faculty of Medicine, Charles University, Prague, Czech Republic
    Can J Physiol Pharmacol 75:1181-7. 1997
    ..This response to porphyrogenic drugs resembles the response observed in human acute porphyrias...