Research TopicsGenomes and GenesSpecies | Marek MrazSummaryAffiliation: Charles University Country: Czech Republic Publications
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Detail Information
Publications
MicroRNA-650 expression is influenced by immunoglobulin gene rearrangement and affects the biology of chronic lymphocytic leukemiaMarek Mraz
Center of Molecular Medicine, Central European Institute of Technology, Masaryk University, Brno, Czech Republic
Blood 119:2110-3. 2012..This study underscores the importance of miR-650 in CLL biology and normal B-cell physiology...
MicroRNAs in chronic lymphocytic leukemia pathogenesis and disease subtypesMarek Mraz
Center of Molecular Biology and Gene Therapy, Department of Internal Medicine Hematooncology, University Hospital Brno and Medical Faculty MU, Brno, Czech Republic
Leuk Lymphoma 50:506-9. 2009..Consequently, these three miRNAs could potentially play important roles in the pathogenesis of aggressive CLL...
MicroRNAs regulate p21(Waf1/Cip1) protein expression and the DNA damage response in human embryonic stem cellsDasa Dolezalova
Department of Histology and Embryology, Faculty of Medicine, Masaryk University, Kamenice 3 A1, Brno, Czech Republic
Stem Cells 30:1362-72. 2012..The described mechanism elucidates the role of miRNAs in regulation of important molecular pathway governing the G1/S transition checkpoint before as well as after DNA damage...
Gene expression profiling of acute graft-vs-host disease after hematopoietic stem cell transplantationJan Verner
Central European Institute of Technology, Masaryk University, Brno, Czech Republic Center of Molecular Biology and Gene Therapy, Department of Internal Medicine, Hematology and Oncology, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic
Exp Hematol 40:899-905.e5. 2012..This indicates an involvement of similar immune regulatory pathways also in aGVHD. Our data support use of gene expression profiling at aGVHD onset for a prediction of its outcomes...
