Affiliation: Charles University
Country: Czech Republic
Skalova S, Svadlakova T, Shaikh Qureshi W, Dev K, Mokry J. Induced pluripotent stem cells and their use in cardiac and neural regenerative medicine. Int J Mol Sci. 2015;16:4043-67 pubmed publisher
..Despite the promising potential of iPSCs, genome contamination and low efficacy of cell reprogramming remain significant challenges. ..
HrebÃkovÃ¡ H, ÄŒÃÅ¾kovÃ¡ D, ChvÃ¡talovÃ¡ J, Pisal R, AdamÄik R, Beznoska P, et al
. Cell Stratification, Spheroid Formation and Bioscaffolds Used to Grow Cells in Three Dimensional Cultures. Acta Medica (Hradec Kralove). 2015;58:79-85 pubmed publisher
..The recellularized scaffolds did not reach high cell densities comparable with the former systems but supported well cell anchorage and migration without any signs of cell regression. ..
Mokry J, Soukup T, Micuda S, Karbanova J, Visek B, Brcakova E, et al
. Telomere attrition occurs during ex vivo expansion of human dental pulp stem cells. J Biomed Biotechnol. 2010;2010:673513 pubmed publisher
Pisal R, Suchanek J, Siller R, Soukup T, Hrebíková H, Bezrouk A, et al
. Directed reprogramming of comprehensively characterized dental pulp stem cells extracted from natal tooth. Sci Rep. 2018;8:6168 pubmed publisher
..Based on our findings, nDPSC present a unique marker expression profile compared with adult DPSC and possess higher reprogramming efficiency as compared with dermal fibroblasts thus proving to be more amenable for reprogramming. ..
Rishikaysh P, Dev K, Diaz D, Qureshi W, Filip S, Mokry J. Signaling involved in hair follicle morphogenesis and development. Int J Mol Sci. 2014;15:1647-70 pubmed publisher
..The dermal Wnt pathway helps in upregulation of epithelial Notch expression. Dysregulation of these pathways leads to certain abnormalities and in some cases even tumor outgrowth. ..
Mokry J, Cizkova D, Filip S, Ehrmann J, Osterreicher J, Kolar Z, et al
. Nestin expression by newly formed human blood vessels. Stem Cells Dev. 2004;13:658-64 pubmed
..Because nestin expression was recognized under all conditions of vascular development, nestin represents a novel and reliable marker of neovascularization. ..
Mokry J, Pudil R, Ehrmann J, Cizkova D, Osterreicher J, Filip S, et al
. Re-expression of nestin in the myocardium of postinfarcted patients. Virchows Arch. 2008;453:33-41 pubmed publisher
..These findings document a crucial role of nestin in remodeling cytoskeleton of cells in the human postinfarcted myocardium. ..