Jan Laco

Summary

Affiliation: Charles University
Country: Czech Republic

Publications

  1. doi request reprint Idiopathic vs. secondary retroperitoneal fibrosis: a clinicopathological study of 12 cases, with emphasis to possible relationship to IgG4-related disease
    Jan Laco
    The Fingerland Department of Pathology, Faculty of Medicine and University Hospital in Hradec Kralove, Charles University in Prague, Sokolska 581, 500 05, Hradec Kralove, Czech Republic
    Virchows Arch 463:721-30. 2013
  2. doi request reprint Mammary analog secretory carcinoma of salivary glands: a report of 2 cases with expression of basal/myoepithelial markers (calponin, CD10 and p63 protein)
    Jan Laco
    The Fingerland Department of Pathology, Charles University Faculty of Medicine and Faculty Hospital Hradec Králové, Czech Republic
    Pathol Res Pract 209:167-72. 2013
  3. doi request reprint Cribriform adenocarcinoma of minor salivary glands may express galectin-3, cytokeratin 19, and HBME-1 and contains polymorphisms of RET and H-RAS proto-oncogenes
    Jan Laco
    The Fingerland Department of Pathology, Charles University Faculty of Medicine and Faculty Hospital, Sokolska 581, 500 05 Hradec Kralove, Czech Republic
    Virchows Arch 461:531-40. 2012
  4. doi request reprint Biologic importance and prognostic significance of selected clinicopathological parameters in patients with oral and oropharyngeal squamous cell carcinoma, with emphasis on smoking, protein p16(INK4a) expression, and HPV status
    J Laco
    The Fingerland Department of Pathology, Charles University Faculty of Medicine and Faculty Hospital in Hradec Kralove, Czech Republic
    Neoplasma 59:398-408. 2012
  5. ncbi request reprint [Anaplastic carcinoma of the thyroid gland with chondrosarcomatous component]
    J Laco
    Fingerlanduv ustav patologie, LF UK a FN, Hradec Kralove
    Cesk Patol 41:34-7. 2005
  6. ncbi request reprint [Congenital granular cell epulis: a case report]
    J Laco
    Fingerlanduv ustav patologie, Lékarská fakulta UK a Fakultní nemocnice, Hradec Kralove
    Cesk Patol 45:117-9. 2009
  7. doi request reprint Isolated thoracic aortitis: clinicopathological and immunohistochemical study of 11 cases
    Jan Laco
    The Fingerland Department of Pathology, Charles University Faculty of Medicine and Faculty Hospital in Hradec Kralove, Hradec Kralove, Czech Republic
    Cardiovasc Pathol 20:352-60. 2011
  8. doi request reprint Low-grade cribriform cystadenocarcinoma of the parotid gland: a neoplasm with favorable prognosis, distinct from salivary duct carcinoma
    Jan Laco
    The Fingerland Department of Pathology, Charles University Faculty of Medicine and Faculty Hospital in Hradec Kralove, Czech Republic
    Int J Surg Pathol 18:369-73. 2010
  9. doi request reprint The role of high-risk human papillomavirus infection in oral and oropharyngeal squamous cell carcinoma in non-smoking and non-drinking patients: a clinicopathological and molecular study of 46 cases
    Jan Laco
    The Fingerland Department of Pathology, Faculty of Medicine and Faculty Hospital in Hradec Kralove, Charles University, Sokolska 581, 500 05, Hradec Kralove, Czech Republic
    Virchows Arch 458:179-87. 2011
  10. ncbi request reprint [IgG4-related systemic sclerosing disease: a review]
    J Laco
    Fingerlanduv ustav patologie, Lékarská fakulta UK a Fakultní nemocnice, Hradec Kralove
    Cesk Patol 46:82-5. 2010

Detail Information

Publications31

  1. doi request reprint Idiopathic vs. secondary retroperitoneal fibrosis: a clinicopathological study of 12 cases, with emphasis to possible relationship to IgG4-related disease
    Jan Laco
    The Fingerland Department of Pathology, Faculty of Medicine and University Hospital in Hradec Kralove, Charles University in Prague, Sokolska 581, 500 05, Hradec Kralove, Czech Republic
    Virchows Arch 463:721-30. 2013
    ..Our results indicate that a substantial portion of iRF cases, including some of very rare pediatric cases, is a manifestation of IgG4-RD...
  2. doi request reprint Mammary analog secretory carcinoma of salivary glands: a report of 2 cases with expression of basal/myoepithelial markers (calponin, CD10 and p63 protein)
    Jan Laco
    The Fingerland Department of Pathology, Charles University Faculty of Medicine and Faculty Hospital Hradec Králové, Czech Republic
    Pathol Res Pract 209:167-72. 2013
    ..Both neoplasms harbored the ETV6-NTRK3 fusion transcript as proved by RT-PCR. Although previously reported only rarely, we conclude that MASC may show expression of basal/myoepithelial markers...
  3. doi request reprint Cribriform adenocarcinoma of minor salivary glands may express galectin-3, cytokeratin 19, and HBME-1 and contains polymorphisms of RET and H-RAS proto-oncogenes
    Jan Laco
    The Fingerland Department of Pathology, Charles University Faculty of Medicine and Faculty Hospital, Sokolska 581, 500 05 Hradec Kralove, Czech Republic
    Virchows Arch 461:531-40. 2012
    ..The RET, H-RAS, and N-RAS proto-oncoogenes are not mutated in CAMSG...
  4. doi request reprint Biologic importance and prognostic significance of selected clinicopathological parameters in patients with oral and oropharyngeal squamous cell carcinoma, with emphasis on smoking, protein p16(INK4a) expression, and HPV status
    J Laco
    The Fingerland Department of Pathology, Charles University Faculty of Medicine and Faculty Hospital in Hradec Kralove, Czech Republic
    Neoplasma 59:398-408. 2012
    ..Smoking itself does not seem to be an important prognostic factor...
  5. ncbi request reprint [Anaplastic carcinoma of the thyroid gland with chondrosarcomatous component]
    J Laco
    Fingerlanduv ustav patologie, LF UK a FN, Hradec Kralove
    Cesk Patol 41:34-7. 2005
    ..The diagnosis of thyroid anaplastic carcinoma with chondrosarcomatous component was established. Differential diagnostics of this tumour is discussed...
  6. ncbi request reprint [Congenital granular cell epulis: a case report]
    J Laco
    Fingerlanduv ustav patologie, Lékarská fakulta UK a Fakultní nemocnice, Hradec Kralove
    Cesk Patol 45:117-9. 2009
    ..5, whereas the proof of S100 protein and inhibin was negative. The postoperative course was uneventful and follow-up for 8 months showed no local recurrence...
  7. doi request reprint Isolated thoracic aortitis: clinicopathological and immunohistochemical study of 11 cases
    Jan Laco
    The Fingerland Department of Pathology, Charles University Faculty of Medicine and Faculty Hospital in Hradec Kralove, Hradec Kralove, Czech Republic
    Cardiovasc Pathol 20:352-60. 2011
    ..Our results suggest that a subset of ITA may represent aortic manifestation of IgG4-related disease. Further research is necessary in order to clarify this issue...
  8. doi request reprint Low-grade cribriform cystadenocarcinoma of the parotid gland: a neoplasm with favorable prognosis, distinct from salivary duct carcinoma
    Jan Laco
    The Fingerland Department of Pathology, Charles University Faculty of Medicine and Faculty Hospital in Hradec Kralove, Czech Republic
    Int J Surg Pathol 18:369-73. 2010
    ..The patient is free of disease for 2 years. The relationship between low-grade cribriform cystadenocarcinoma and salivary duct carcinoma is discussed...
  9. doi request reprint The role of high-risk human papillomavirus infection in oral and oropharyngeal squamous cell carcinoma in non-smoking and non-drinking patients: a clinicopathological and molecular study of 46 cases
    Jan Laco
    The Fingerland Department of Pathology, Faculty of Medicine and Faculty Hospital in Hradec Kralove, Charles University, Sokolska 581, 500 05, Hradec Kralove, Czech Republic
    Virchows Arch 458:179-87. 2011
    ..00 and 0.73, respectively. Our study is the first larger study analyzing OSCC and OPSCC in NSNDP. Our results indicate that unlike OSCC, a vast majority of OPSCCs may be associated with HR-HPV infection...
  10. ncbi request reprint [IgG4-related systemic sclerosing disease: a review]
    J Laco
    Fingerlanduv ustav patologie, Lékarská fakulta UK a Fakultní nemocnice, Hradec Kralove
    Cesk Patol 46:82-5. 2010
    ..Since SSD frequently mimicks a malignancy both clinically and radiologically, this inflammatory sclerosing condition should be considered in the differential diagnosis of neoplastic and/or pseudoneoplastic lesions...
  11. doi request reprint Chronic sclerosing sialadenitis as one of the immunoglobulin G4-related diseases: a clinicopathological study of six cases from Central Europe
    Jan Laco
    The Fingerland Department of Pathology, Charles University Faculty of Medicine and Faculty Hospital in Hradec Kralove, Czech Republic
    Histopathology 58:1157-63. 2011
    ..Chronic sclerosing sialadenitis (CSS) has been proposed recently to be a member of the group of IgG4-related diseases in Japanese and American series. The aim of our study was to validate these results in a cohort of European patients...
  12. doi request reprint Atypical lipomatous tumors of the tongue: report of six cases
    Jan Laco
    The Fingerland Department of Pathology, Charles University Medical Faculty and Faculty Hospital in Hradec Kralove, Hradec Kralove, Czech Republic
    Virchows Arch 455:383-8. 2009
    ..Although most ALTs of the tongue behave in the nonaggressive fashion, they may recur locally. Based on current data, the term ALT is strongly recommended for tumors occurring in the tongue to prevent inadequate treatment...
  13. ncbi request reprint Recurrent mucinous carcinoma of skin mimicking primary mucinous carcinoma of parotid gland: a diagnostic pitfall
    J Laco
    The Fingerland Department of Pathology, Charles University Faculty of Medicine and Faculty Hospital in Hradec Kralove, Czech Republic
    Cesk Patol 45:79-82. 2009
    ..The patient underwent radiotherapy and has been 3 years free of disease. The differential diagnostics of this rare tumor is discussed...
  14. doi request reprint Tumor-to-tumor metastasis: Warthin tumor as a recipient of lung carcinoma and of renal carcinoma - Report of two cases
    Jan Laco
    The Fingerland Department of Pathology, Charles University Faculty of Medicine and Faculty Hospital in Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic
    Pathol Res Pract 206:458-62. 2010
    ..To the best of our knowledge, such a phenomenon has not been reported so far...
  15. ncbi request reprint [The use of immunohistochemistry in the differential diagnosis of thyroid gland tumors with follicular growth pattern]
    J Laco
    Fingerlanduv ustav patologie, Lékarská fakulta UK a FN, Hradec Kralove
    Cesk Patol 42:120-4. 2006
    ..05) in expression of all studied markers between FVPC versus FA and FC was found, in contrast to FA and FC. Therefore, the use of gal3 and CK19 in differential diagnosis of FVPC versus FA and FC can be recommended...
  16. ncbi request reprint Expression of galectin-3, cytokeratin 19, neural cell adhesion molecule and E-cadhedrin in certain variants of papillary thyroid carcinoma
    J Laco
    The Fingerland Department of Pathology, Charles University Faculty of Medicine and Faculty Hospital in Hradec Kralove
    Cesk Patol 44:103-7. 2008
    ..001, p = 0.04). Our findings suggest that Gal3 and CK19 are useful markers for PTC, although decreased CK19 expression in mPTC and fPTC must be considered. Furthermore, CK19 and Ecad may play a role in extrathyroid tumor spread...
  17. ncbi request reprint Low grade myofibroblastic sarcoma of tongue: a case report
    J Laco
    The Fingerland Department of Pathology, Charles University Faculty of Medicine and Faculty Hospital in Hradec Kralove
    Cesk Patol 42:150-3. 2006
    ..Although the tumor resection was not complete, the patient is free of disease 1 year after operation. The differential diagnostics of low grade myofibroblastic sarcoma is discussed...
  18. doi request reprint Nonbacterial thrombotic endocarditis involving all four cardiac valves
    Jan Laco
    The Fingerland Department of Pathology, Faculty of Medicine and Faculty Hospital, Charles University, Sokolska 581, 500 05 Hradec Kralove, Czech Republic
    Pathol Res Pract 204:757-61. 2008
    ..Microscopically, neither microorganisms nor inflammation were found in the thrombi and/or valve tissues. To the best of our knowledge, this is the fourth case of quadri-valvular NBTE reported in the English-written literature so far...
  19. doi request reprint High-risk human papillomavirus infection and p16INK4a protein expression in laryngeal lesions
    Jan Laco
    The Fingerland Department of Pathology, Faculty of Medicine and Faculty Hospital in Hradec Kralove, Charles University in Prague, Hradec Kralove, Czech Republic
    Pathol Res Pract 204:545-52. 2008
    ..612 and 0.773, respectively. Our study confirms a potential role of HR-HPV infection not only in the pathogenesis of malignant, but also in benign laryngeal lesions...
  20. ncbi request reprint [Lipomatous hypertrophy of the cardiac interatrial septum]
    J Laco
    Fingerlandův ústav patologie LF UK a FN, Hradec Kralove
    Cesk Patol 42:182-5. 2006
    ....
  21. ncbi request reprint [Extrapleural solitary fibrous tumor mimicking lateral neck cyst--a case report]
    J Laco
    Fingerlandfův ustav patologie, Lékarská fakulta UK a Fakultní nemocnice, Hradec Kralove
    Cesk Patol 43:68-72. 2007
    ..One year after resection, the patient is free of disease. A new concept of this uncommon mesenchymal tumor is discussed...
  22. doi request reprint Mammary analogue secretory carcinoma of salivary glands with high-grade transformation: report of 3 cases with the ETV6-NTRK3 gene fusion and analysis of TP53, β-catenin, EGFR, and CCND1 genes
    Alena Skalova
    Department of Pathology, Faculty of Medicine in Plzen, Charles University in Prague Bioptic Laboratory Ltd Bioptic Laboratory Ltd, Molecular Pathology Laboratory Department of Maxillofacial Surgery, Faculty of Medicine, Clinic of Dentistry, Plzen The Fingerland Department of Pathology, Faculty of Medicine and University Hospital, Charles University in Prague, Hradec Kralove, Czech Republic Department of Pathology, Medical University of Gdansk, Poland Department of Anatomical Pathology, University of Calgary and Foothills Medical Centre, Calgary, AB, Canada
    Am J Surg Pathol 38:23-33. 2014
    ..Recognizing HG-transformed MASC and testing for ETV6 rearrangement may be of potential value in patient treatment, because the presence of the ETV6-NTRK3 translocation may represent a therapeutic target in MASC. ..
  23. doi request reprint Repair of thoracic aortic aneurysm due to noninfectious aortitis
    Tomas Holubec
    Department of Cardiac Surgery, Charles University in Prague, Faculty of Medicine and University Hospital in Hradec Kralove, Czech Republic
    J Card Surg 27:199-204. 2012
    ..We investigated patients on whom the ascending aorta was operated to identify the clinical and histopathological features of ITA and its relationship to IgG4-related systemic disease...
  24. doi request reprint Mammary analogue secretory carcinoma of salivary glands, containing the ETV6-NTRK3 fusion gene: a hitherto undescribed salivary gland tumor entity
    Alena Skalova
    Department of Pathology, Charles University, Pilsen, Czech Republic
    Am J Surg Pathol 34:599-608. 2010
    ..Thus, our results strongly support the concept that MASC and AciCC are different entities...
  25. doi request reprint Calcific aortic valve stenosis: Immunohistochemical analysis of inflammatory infiltrate
    Ivo Steiner
    The Fingerland Department of Pathology, Charles University Faculty of Medicine and Faculty Hospital in Hradec Kralove, Czech Republic
    Pathol Res Pract 208:231-4. 2012
    ..The inflammatory process was the same in both subsets of CAS - those with trileaflet (normally formed) valves and those with congenitally bicuspid valves...
  26. ncbi request reprint [What is your diagnosis? Answer: epithelial-myoepithelial carcinoma (EMCa)]
    Jan Laco
    Cesk Patol 41:101, 118-9. 2005
  27. ncbi request reprint [Rokitansky on atherosclerosis]
    I Steiner
    Fingerlanduv ustav patologie, Lékarské fakulty UK a Fakultní nemocnice, Hradec Kralove
    Cesk Patol 44:23-4. 2008
    ..In the third edition of Rokitansky's textbook issued 12 years later there are already included histological drawings of the aortic intimal and medial lesions...
  28. doi request reprint Prognostic Significance of Human Papillomavirus (HPV) Status and Expression of Selected Markers (HER2/neu, EGFR, VEGF, CD34, p63, p53 and Ki67/MIB-1) on Outcome After (Chemo-) Radiotherapy in Patients with Squamous Cell Carcinoma of Uterine Cervix
    Milan Vosmik
    Department of Oncology and Radiotherapy, University Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic
    Pathol Oncol Res 20:131-7. 2014
    ..In conclusion, the presented study did not confirm any apparently significant association of the suggested markers with prognosis of SCCC in patients treated with (chemo-) radiotherapy. ..
  29. doi request reprint Pleomorphic adenoma of the salivary glands with intravascular tumor deposits: a diagnostic pitfall
    Alena Skalova
    Department of Pathology, Charles University, Faculty of Medicine in Plzen, Czech Republic
    Am J Surg Pathol 36:1674-82. 2012
    ....
  30. ncbi request reprint Expression of matrix metalloproteinase 9 in patients with oral lichen planus
    Vladimíra Paulusová
    Charles University in Prague, Faculty of Medicine and University Hospital in Hradec Kralove, Czech Republic
    Acta Medica (Hradec Kralove) 55:23-6. 2012
    ..Basement membrane damage and T-cell migration in OLP may be mediated by matrix metalloproteinases (MMPs). We examined the expression of matrix metalloproteinase 9 to support this hypothesis...
  31. doi request reprint Fulminant hepatitis and death associated with disseminated varicella in an immunocompromised adult from the Czech Republic caused by a wild-type clade 4 varicella-zoster virus strain
    Stanislav Plisek
    Department of Infectious Diseases, Charles University Medical School and University Hospital, Hradec Kralove, Czech Republic
    J Clin Virol 50:72-5. 2011
    ..This is the first description of a clade 4 strain from a patient in the Czech Republic...