Affiliation: Charles University
Country: Czech Republic
- Evaluation of mitochondrial membrane potential using a computerized device with a tetraphenylphosphonium-selective electrodeAnna Labajova
Institute of Pathophysiology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic
Anal Biochem 353:37-42. 2006..Our system can be successfully used for studies of many aspects of the regulation of mitochondrial bioenergetics and as a diagnostic tool for mitochondrial oxidative phosphorylation disorders...
- Mechanisms participating in oxidative damage of isolated rat hepatocytesZuzana Cervinkova
Department of Physiology, Faculty of Medicine, Charles University, Hradec Kralove, Czech Republic
Arch Toxicol 83:363-72. 2009..In the presence of cyclosporine A and succinate, the membrane potential could be restored. Our data showed that the most sensitive indicators of the peroxidative damage are changes of cytosolic glutathione concentration and MMP...