Marcela Kopacova

Summary

Affiliation: Charles University
Country: Czech Republic

Publications

  1. ncbi request reprint Confocal laser endomicroscopy in experimental pigs. Methods of ex vivo imaging
    M Kopacova
    Second Department of Internal Medicine, Charles University in Praha, Faculty of Medicine at Hradec Kralove, University Teaching Hospital, Hradec Kralove, Czech Republic
    Cas Lek Cesk 148:249-53. 2009
  2. ncbi request reprint [Double-balloon enteroscopy]
    M Kopacova
    Univerzita Karlova v Praze, LF a FN Hradec Králové
    Cas Lek Cesk 148:91-6. 2009
  3. pmc Wireless video capsule enteroscopy in preclinical studies: methodical design of its applicability in experimental pigs
    Marcela Kopacova
    Second Department of Internal Medicine, Faculty of Medicine at Hradec Kralove, Charles University in Praha, University Teaching Hospital, Hradec Kralove, Czech Republic
    Dig Dis Sci 55:626-30. 2010
  4. pmc Inverted Meckel's diverticulum with ectopic pancreatic tissue as a source of severe gastrointestinal bleeding
    Marcela Kopacova
    Second Department of Internal Medicine, Faculty of Medicine at Hradec Kralove, Charles University in Praha, University Teaching Hospital, Hradec Kralove, Czech Republic
    J Gastrointest Surg 14:578-81. 2010
  5. doi request reprint Comparison of intraoperative enteroscopy and double-balloon enteroscopy for the diagnosis and treatment of Peutz-Jeghers syndrome
    Marcela Kopacova
    2nd Department of Medicine, Faculty of Medicine at Hradec Kralove, Charles University in Praha, University Teaching Hospital, Sokolska 581, Hradec Kralove, 500 05 Czech Republic
    Surg Endosc 24:1904-10. 2010
  6. pmc Double balloon enteroscopy and acute pancreatitis
    Marcela Kopacova
    2nd Department of Medicine, Charles University Teaching Hospital, , , Czech Republic
    World J Gastroenterol 16:2331-40. 2010
  7. ncbi request reprint Tumorous neo-vascularization: a newly recognized endoscopic feature of intestinal non-Hodgkin lymphoma
    M Kopacova
    2nd Department of Internal Medicine, Charles University in Praha, Faculty of Medicine at Hradec Kralove, University Teaching Hospital, Hradec Kralove, Czech Republic
    Endoscopy 39:E95. 2007
  8. ncbi request reprint A new approach to blue rubber bleb nevus syndrome: the role of capsule endoscopy and intra-operative enteroscopy
    Marcela Kopacova
    2nd Department of Medicine, Charles University in Praha, Faculty of Medicine at Hradec Kralove, University Teaching Hospital, Sokolska 581, Hradec Kralove, 500 05, Czech Republic
    Pediatr Surg Int 23:693-7. 2007
  9. pmc Body indices and basic vital signs in Helicobacter pylori positive and negative persons
    Marcela Kopacova
    2nd Department of Medicine, Charles University in Praha, Faculty of Medicine at Hradec Kralove, University Teaching Hospital, Sokolska 581, 500 05, Hradec Kralove, Czech Republic
    Eur J Epidemiol 22:67-75. 2007
  10. ncbi request reprint Comparison of different protocols for 13C-urea breath test for the diagnosis of Helicobacter pylori infection in healthy volunteers
    M Kopacova
    Second Department of Internal Medicine, Charles University, Prague, Czech Republic
    Scand J Clin Lab Invest 65:491-8. 2005

Detail Information

Publications36

  1. ncbi request reprint Confocal laser endomicroscopy in experimental pigs. Methods of ex vivo imaging
    M Kopacova
    Second Department of Internal Medicine, Charles University in Praha, Faculty of Medicine at Hradec Kralove, University Teaching Hospital, Hradec Kralove, Czech Republic
    Cas Lek Cesk 148:249-53. 2009
    ..The aim of this study was to work out a method of ex vivo in vitro CLSE in experimental pigs and to compare CLSE images with those of "classic" histology...
  2. ncbi request reprint [Double-balloon enteroscopy]
    M Kopacova
    Univerzita Karlova v Praze, LF a FN Hradec Králové
    Cas Lek Cesk 148:91-6. 2009
    ..The DBE has a potential to be a standard of enteroscopy by replacing conventional push enteroscopy. DBE together with the capsule endoscopy are the essential modalities for the management of small intestinal diseases...
  3. pmc Wireless video capsule enteroscopy in preclinical studies: methodical design of its applicability in experimental pigs
    Marcela Kopacova
    Second Department of Internal Medicine, Faculty of Medicine at Hradec Kralove, Charles University in Praha, University Teaching Hospital, Hradec Kralove, Czech Republic
    Dig Dis Sci 55:626-30. 2010
    ..Capsule endoscopy in experimental pigs will be helpful for future trials on injury of different drugs and xenobiotics to the small bowel...
  4. pmc Inverted Meckel's diverticulum with ectopic pancreatic tissue as a source of severe gastrointestinal bleeding
    Marcela Kopacova
    Second Department of Internal Medicine, Faculty of Medicine at Hradec Kralove, Charles University in Praha, University Teaching Hospital, Hradec Kralove, Czech Republic
    J Gastrointest Surg 14:578-81. 2010
    ..Inverted Meckel's diverticulum with ectopic pancreatic tissue as a source of severe gastrointestinal bleeding was diagnosed by intraoperative enteroscopy...
  5. doi request reprint Comparison of intraoperative enteroscopy and double-balloon enteroscopy for the diagnosis and treatment of Peutz-Jeghers syndrome
    Marcela Kopacova
    2nd Department of Medicine, Faculty of Medicine at Hradec Kralove, Charles University in Praha, University Teaching Hospital, Sokolska 581, Hradec Kralove, 500 05 Czech Republic
    Surg Endosc 24:1904-10. 2010
    ..Bleeding, obstruction, and intussusception are common complications in patients with PJS. The goal of this study was compare our experience in diagnosis and treatment of small-bowel hamartomas by means of DBE and IOE...
  6. pmc Double balloon enteroscopy and acute pancreatitis
    Marcela Kopacova
    2nd Department of Medicine, Charles University Teaching Hospital, , , Czech Republic
    World J Gastroenterol 16:2331-40. 2010
    ..The most probable cause seems to be a mechanical straining of the endoscope with over-tube on the pancreas or in the papillary area...
  7. ncbi request reprint Tumorous neo-vascularization: a newly recognized endoscopic feature of intestinal non-Hodgkin lymphoma
    M Kopacova
    2nd Department of Internal Medicine, Charles University in Praha, Faculty of Medicine at Hradec Kralove, University Teaching Hospital, Hradec Kralove, Czech Republic
    Endoscopy 39:E95. 2007
  8. ncbi request reprint A new approach to blue rubber bleb nevus syndrome: the role of capsule endoscopy and intra-operative enteroscopy
    Marcela Kopacova
    2nd Department of Medicine, Charles University in Praha, Faculty of Medicine at Hradec Kralove, University Teaching Hospital, Sokolska 581, Hradec Kralove, 500 05, Czech Republic
    Pediatr Surg Int 23:693-7. 2007
    ..Capsule endoscopy is a feasible non-invasive screening procedure. We believe that a radical eliminatory approach by means of combined surgery and IOE is indicated for the BRBNS to prevent ongoing gastrointestinal bleeding...
  9. pmc Body indices and basic vital signs in Helicobacter pylori positive and negative persons
    Marcela Kopacova
    2nd Department of Medicine, Charles University in Praha, Faculty of Medicine at Hradec Kralove, University Teaching Hospital, Sokolska 581, 500 05, Hradec Kralove, Czech Republic
    Eur J Epidemiol 22:67-75. 2007
    ..Unmeasured factors related to social and family environment may cause the apparent association between Hp positivity and children's growth and blood pressure...
  10. ncbi request reprint Comparison of different protocols for 13C-urea breath test for the diagnosis of Helicobacter pylori infection in healthy volunteers
    M Kopacova
    Second Department of Internal Medicine, Charles University, Prague, Czech Republic
    Scand J Clin Lab Invest 65:491-8. 2005
    ..However, several methodological issues have not been resolved yet. The aim of this study was to test different protocols of (13)C-UBT to find the optimal test drink and sampling interval...
  11. pmc Peutz-Jeghers syndrome: diagnostic and therapeutic approach
    Marcela Kopacova
    2nd Department of Medicine, Charles University in Praha, Faculty of Medicine at Hradec Kralove, University Teaching Hospital, Sokolska 581, Hradec Kralove 500 05, Czech Republic
    World J Gastroenterol 15:5397-408. 2009
    ..Although the incidence of PJS is low, it is important for clinicians to recognize these disorders to prevent morbidity and mortality in these patients, and to perform presymptomatic testing in the first-degree relatives of PJS patients...
  12. ncbi request reprint Intraoperative enteroscopy: ten years' experience at a single tertiary center
    M Kopacova
    2nd Department of Medicine, Charles University in Praha, Faculty of Medicine at Hradec Kralove, University Teaching Hospital, Sokolska 581, Hradec Kralove, 500 05, Czech Republic
    Surg Endosc 21:1111-6. 2007
    ..It enables us to investigate the entire small intestine and to treat pathological findings by endoscopic or surgical means at the same time. The investigation is invasive and that is why the proper indication is mandatory...
  13. doi request reprint Prevalence and sociodemographic determinants of uninvestigated dyspepsia in the Czech Republic
    Stanislav Rejchrt
    2nd Department of Medicine, Charles University eESPCG, Praha, Czech Republic
    Eur J Gastroenterol Hepatol 20:898-905. 2008
    ..There are no data on the epidemiology of dyspepsia in Central Europe. The aim of this study was to evaluate the prevalence of uninvestigated dyspepsia in a representative sample of the Czech population...
  14. doi request reprint Wireless capsule endoscopy in enteropathy induced by nonsteroidal anti-inflammatory drugs in pigs
    Ilja Tacheci
    Second Department of Internal Medicine, Charles University in Praha, Faculty of Medicine at Hradec Kralove, University Teaching Hospital, Hradec Kralove, Czech Republic
    Dig Dis Sci 55:2471-7. 2010
    ..The aim of this study is to evaluate the diagnostic yield of capsule endoscopy in nonsteroidal anti-inflammatory drug (NSAID)-induced enteropathy in pigs...
  15. pmc Significant decrease in prevalence of Helicobacter pylori in the Czech Republic
    Jan Bures
    Second Department of Medicine Gastroenterology, Charles University in Praha, Faculty of Medicine at Hradec Kralove, University Teaching Hospital, 50005 Hradec Kralove, Czech Republic
    World J Gastroenterol 18:4412-8. 2012
    ..To study possible decrease in prevalence of Helicobacter pylori (H. pylori) infection in the Czech Republic within a 10-year period...
  16. pmc Bacteriocinogeny in experimental pigs treated with indomethacin and Escherichia coli Nissle
    Jan Bures
    2nd Department of Medicine, Charles University in Praha, Faculty of Medicine at Hradec Kralove, University Teaching Hospital, 500 05 Hradec Kralove, Czech Republic
    World J Gastroenterol 17:609-17. 2011
    ..To evaluate bacteriocinogeny in short-term high-dose indomethacin administration with or without probiotic Escherichia coli Nissle 1917 (EcN) in experimental pigs...
  17. ncbi request reprint Epidemiology of Helicobacter pylori infection in the Czech Republic
    Jan Bures
    2nd Department of Medicine, Charles University in Praha, Faculty of Medicine at Hradec Kralove, University Teaching Hospital, Hradec Kralove, Czech Republic
    Helicobacter 11:56-65. 2006
    ..pylori infection prevalence in a representative sample of the Czech population. The second objective was to describe difference of H. pylori prevalence between different social groups of children and adults...
  18. ncbi request reprint The use of wireless capsule enteroscopy in a preclinical study: a novel diagnostic tool for indomethacin-induced gastrointestinal injury in experimental pigs
    Jaroslav Kvetina
    Institute of Experimental Biopharmaceutics, Joint Research Centre of the Czech Academy of Sciences and PRO MED CS Praha a s, Hradec Kralove, Czech Republic
    Neuro Endocrinol Lett 29:763-9. 2008
    ..Consequently, there is a demonstration of the extrems of gastrointestinal lesions development induced with indomethacin as a representative of non-steroidal anti-inflammatory drug...
  19. ncbi request reprint Electrogastrography in experimental pigs: the influence of gastrointestinal injury induced by dextran sodium sulphate on porcine gastric erythromycin-stimulated myoelectric activity
    Ilja Tacheci
    2nd Department of Medicine, Charles University in Prague, Faculty of Medicine in Hradec Kralove, University Teaching Hospital, Hradec Kralove, Czech Republic
    Neuro Endocrinol Lett 32:131-6. 2011
    ..The aim of study was to evaluate the impact of erythromycin on EGG in gastrointestinal toxic injury induced by dextran sodium sulphate (DSS) in experimental pigs...
  20. ncbi request reprint Impact of paraoxon followed by acetylcholinesterase reactivator HI-6 on gastric myoelectric activity in experimental pigs
    Jan Bures
    2nd Department of Internal Medicine Gastroenterology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic
    Neuro Endocrinol Lett 34:79-83. 2013
    ..In this study we evaluated the effect of paraoxon and an AChE reactivator (HI-6) on the gastric myoelectric activity in experimental pigs...
  21. pmc The effect of general anaesthesia on gastric myoelectric activity in experimental pigs
    Ilja Tacheci
    2nd Department of Internal Medicine Gastroenterology, Charles University in Prague, Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic
    BMC Gastroenterol 13:48. 2013
    ..Different forms of general anaesthesia might have various effects on porcine EGG. The aim of this study was to evaluate the impact of different anaesthetic agents on EGG in experimental pigs...
  22. pmc Different solutions used for submucosal injection influenced early healing of gastric endoscopic mucosal resection in a preclinical study in experimental pigs
    Jan Bures
    Second Department of Internal Medicine, Charles University in Praha, Faculty of Medicine at Hradec Kralove, University Teaching Hospital, Sokolska 581, 500 05, Hradec Kralove, Czech Republic
    Surg Endosc 23:2094-101. 2009
    ..The aim of this study was to evaluate histological and immunological changes after EMR in experimental pigs...
  23. pmc Small intestinal bacterial overgrowth syndrome
    Jan Bures
    2nd Department of Medicine, Charles University in Praha, Faculty of Medicine at Hradec Kralove, University Teaching Hospital, Sokolska 581, 500 05 Hradec Kralove, Czech Republic
    World J Gastroenterol 16:2978-90. 2010
    ..It should include treatment of the underlying disease, nutritional support and cyclical gastro-intestinal selective antibiotics. Prognosis is usually serious, determined mostly by the underlying disease that led to SIBO...
  24. ncbi request reprint Non-steroidal anti-inflammatory drug induced injury to the small intestine
    Ilja Tacheci
    Charles University in Praha, Faculty of Medicine and 2nd Department of Internal Medicine, Division of Gastroenterology, University Hospital Hradec Kralove, Czech Republic
    Acta Medica (Hradec Kralove) 53:3-11. 2010
    ..Double balloon enteroscopy plays an important role in the treatment of complications (bleeding, strictures)...
  25. ncbi request reprint A prospective, observational study of colonic mucosal abnormalities associated with orally administered sodium phosphate for colon cleansing before colonoscopy
    Stanislav Rejchrt
    Clinical Center, 2nd Department of Medicine, The Fingerland Institute of Pathology, Charles University Teaching Hospital, Hradec Kralove, Czech Republic
    Gastrointest Endosc 59:651-4. 2004
    ..The aim of this prospective study was to determine the frequency at which these occur and to define the endoscopic and histopathologic patterns of these changes...
  26. ncbi request reprint Hyperamylasemia of uncertain significance associated with oral double-balloon enteroscopy
    Marcela Kopacova
    2nd Department of Medicine, Charles University in Praha, Faculty of Medicine at Hradec Kralove, University Teaching Hospital, Hradec Kralove, Czech Republic
    Gastrointest Endosc 66:1133-8. 2007
    ..Double-balloon enterocopy (DBE) is still under evaluation, including its yield and safety aspects...
  27. ncbi request reprint Electrogastrography in patients with Roux-en-Y reconstruction after previous Billroth gastrectomy
    Jan Bures
    Second Department of Internal Medicine, Charles University in Praha, Faculty of Medicine at Hradec Kralove, University Teaching Hospital, Hradec Kralove, Czech Republic
    Hepatogastroenterology 55:1492-6. 2008
    ..The aim of this prospective study was to characterize gastric myoelectrical activity in patients with Roux-en-Y reconstruction after previous Billroth gastrectomy...
  28. pmc Preclinical electrogastrography in experimental pigs
    Jaroslav Kvetina
    Institute of Experimental Biopharmaceutics, Joint Research Centre of Czech Academy of Sciences and PRO MED CS Praha as, Hradec Kralove, Czech Republic
    Interdiscip Toxicol 3:53-8. 2010
    ..The mean dominant frequency in pigs is comparable with that found in humans. EGG in experimental pigs is feasible. Experimental EGG is an important basis for further preclinical projects in pharmacology and toxicology...
  29. pmc Technological advances in radiotherapy for esophageal cancer
    Milan Vosmik
    Department of Oncology and Radiotherapy, Charles University in Praha, Faculty of Medicine at Hradec Kralove, University Teaching Hospital in Hradec Kralove, Sokolska 581, 50005 Hradec Kralove, Czech Republic
    World J Gastroenterol 16:5555-64. 2010
    ..Reduction of radiotherapy-related toxicity is fundamental to the improvement of clinical results in esophageal cancer, although the dose escalation concept is controversial...
  30. doi request reprint Single-photon emission computed tomography enhanced Tc-99m-pertechnetate disodium-labelled red blood cell scintigraphy in the localization of small intestine bleeding: a single-centre twelve-year study
    Jiri Dolezal
    Department of Nuclear Medicine, Charles University in Prague, Faculty of Medicine in Hradec Kralove and Charles University Teaching Hospital, Hradec Kralove, Czech Republic
    Digestion 84:207-11. 2011
    ..To present our experience with the detection of bleeding in the small intestine by means of scintigraphy with in vivo-labelled red blood cells (RBCs) in the period of 1998-2009...
  31. ncbi request reprint Use of bio-degradable stents for the treatment of refractory benign gastrointestinal stenoses
    Stanislav Rejchrt
    2nd Department of Medicine, Charles University in Prague, Faculty of Medicine and University Hospital Hradec Kralove, Czech Republic
    Acta Medica (Hradec Kralove) 54:137-43. 2011
    ..This might be solved by changes in the shape or rigidity of the stents as well as by further improvement in the design. Proof of long-term efficacy and safety requires further studies...
  32. pmc Radionuclide small intestine imaging
    Jiri Dolezal
    Department of Nuclear Medicine, Charles University in Prague, Faculty of Medicine in Hradec Kralove and Charles University Teaching Hospital, Sokolska 581, 500 05 Hradec Kralove, Czech Republic
    Gastroenterol Res Pract 2013:861619. 2013
    ..Radionuclide scintigraphic small intestine imaging is an effective imaging modality in the localisation of small intestine lesions for patients in whom other diagnostic tests have failed to locate any lesions or are not available. ..
  33. pmc Informed consent for digestive endoscopy
    Marcela Kopacova
    Marcela Kopacova, Jan Bures, 2nd Department of Medicine, Faculty of Medicine at Hradec Kralove, University Teaching Hospital, Sokolska 581, 500 05 Hradec Kralove, Czech Republic
    World J Gastrointest Endosc 4:227-30. 2012
    ..The aim is to explain the problem, answer all questions and to ensure that the patient understands the problems and is able to make a decision. The theory is clear but what happens in daily practice?..
  34. ncbi request reprint Incidence of Crohn disease in the Czech Republic in the years 1990 to 2001 and assessment of pediatric population with inflammatory bowel disease
    Oldrich Pozler
    Department of Pediatrics, Charles University Teaching Hospital, 500 05 Hradec Kralove, Czech Republic
    J Pediatr Gastroenterol Nutr 42:186-9. 2006
    ....
  35. ncbi request reprint Cytokine tumor necrosis factor-alpha A promoter gene polymorphism at position -308 G-->A and pediatric inflammatory bowel disease: implications in ulcerative colitis and Crohn's disease
    Josef Sykora
    Department of Pediatrics, Charles University Hospital, Division of Gastroenterology, Pilsen, Czech Republic
    J Pediatr Gastroenterol Nutr 42:479-87. 2006
    ....
  36. ncbi request reprint Development of gastric emptying in premature infants. Use of the (13)C-octanoic acid breath test
    Oldrich Pozler
    Department of Pediatrics, Hradec Kralove, Czech Republic
    Nutrition 19:593-6. 2003
    ..We evaluated (13)C-OABT as a method for assessing gastric emptying in relation to the amount of milk ingested in preterm neonates during their first days of life...