Dmitry V Kazakov

Summary

Affiliation: Charles University
Country: Czech Republic

Publications

  1. doi request reprint Cutaneous apocrine mixed tumor with intravascular tumor deposits: a diagnostic pitfall
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 33:775-9. 2011
  2. doi request reprint Hybrid peripheral nerve sheath tumors, including a malignant variant in type 1 neurofibromatosis
    Denisa Kacerovska
    Sikl s Department of Pathology, Charles University in Prague, Faculty of Medicine in Pilsen, Pilsen, Czech Republic
    Am J Dermatopathol 35:641-9. 2013
  3. doi request reprint Sebaceous differentiation in poroid neoplasms: report of 11 cases, including a case of metaplastic carcinoma associated with apocrine poroma (sarcomatoid apocrine porocarcinoma)
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 30:21-6. 2008
  4. ncbi request reprint Pleomorphic hyalinizing angiectatic tumor with a sarcomatous component recurring as high-grade myxofibrosarcoma
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Pathol Int 57:281-4. 2007
  5. doi request reprint Discordant architectural and cytological features in cutaneous sebaceous neoplasms--a classification dilemma: report of 5 cases
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Bioptical Laboratory, Pilsen, Czech Republic
    Am J Dermatopathol 31:31-6. 2009
  6. doi request reprint Morphologic diversity of malignant neoplasms arising in preexisting spiradenoma, cylindroma, and spiradenocylindroma based on the study of 24 cases, sporadic or occurring in the setting of Brooke-Spiegler syndrome
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Surg Pathol 33:705-19. 2009
  7. ncbi request reprint Primary cutaneous lymphoproliferative disorders with dual lineage rearrangement
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 28:399-409. 2006
  8. doi request reprint Cutaneous hidradenocarcinoma: a clinicopathological, immunohistochemical, and molecular biologic study of 14 cases, including Her2/neu gene expression/amplification, TP53 gene mutation analysis, and t(11;19) translocation
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 31:236-47. 2009
  9. ncbi request reprint Low-grade adnexal carcinoma of the skin with multidirectional (glandular, trichoblastomatous, spiradenocylindromatous) differentiation
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 28:341-5. 2006
  10. ncbi request reprint Clear cell trichoblastoma: a clinicopathological and ultrastructural study of two cases
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 28:197-201. 2006

Detail Information

Publications94

  1. doi request reprint Cutaneous apocrine mixed tumor with intravascular tumor deposits: a diagnostic pitfall
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 33:775-9. 2011
    ..At present, its significance is not completely clear. Until proved otherwise in future, we suggest to consider intravascular deposits in cutaneous apocrine mixed tumors as an innocuous phenomenon...
  2. doi request reprint Hybrid peripheral nerve sheath tumors, including a malignant variant in type 1 neurofibromatosis
    Denisa Kacerovska
    Sikl s Department of Pathology, Charles University in Prague, Faculty of Medicine in Pilsen, Pilsen, Czech Republic
    Am J Dermatopathol 35:641-9. 2013
    ..The malignant component showed areas with an epithelioid cell morphology...
  3. doi request reprint Sebaceous differentiation in poroid neoplasms: report of 11 cases, including a case of metaplastic carcinoma associated with apocrine poroma (sarcomatoid apocrine porocarcinoma)
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 30:21-6. 2008
    ....
  4. ncbi request reprint Pleomorphic hyalinizing angiectatic tumor with a sarcomatous component recurring as high-grade myxofibrosarcoma
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Pathol Int 57:281-4. 2007
    ..Hyalinized, fibrin-containing vessels typical for PHAT were absent. PHAT may be more aggressive than previously thought, and PHAT may encompass a morphological spectrum of the lesion ranging from benign to malignant...
  5. doi request reprint Discordant architectural and cytological features in cutaneous sebaceous neoplasms--a classification dilemma: report of 5 cases
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Bioptical Laboratory, Pilsen, Czech Republic
    Am J Dermatopathol 31:31-6. 2009
    ..Further studies are needed to confirm their seemingly benign course as identified in this report, as are further investigations to clarify their association with Muir-Torre syndrome...
  6. doi request reprint Morphologic diversity of malignant neoplasms arising in preexisting spiradenoma, cylindroma, and spiradenocylindroma based on the study of 24 cases, sporadic or occurring in the setting of Brooke-Spiegler syndrome
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Surg Pathol 33:705-19. 2009
    ....
  7. ncbi request reprint Primary cutaneous lymphoproliferative disorders with dual lineage rearrangement
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 28:399-409. 2006
    ..Further reports are needed to identify these lesions to clarify their nature and biologic potential...
  8. doi request reprint Cutaneous hidradenocarcinoma: a clinicopathological, immunohistochemical, and molecular biologic study of 14 cases, including Her2/neu gene expression/amplification, TP53 gene mutation analysis, and t(11;19) translocation
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 31:236-47. 2009
    ..Even rarer is the amplification of the Her2/neu gene. Of note is the relatively low frequency of TP53 mutations despite a high rate of p53 protein expression at the immunohistochemical level...
  9. ncbi request reprint Low-grade adnexal carcinoma of the skin with multidirectional (glandular, trichoblastomatous, spiradenocylindromatous) differentiation
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 28:341-5. 2006
    ....
  10. ncbi request reprint Clear cell trichoblastoma: a clinicopathological and ultrastructural study of two cases
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 28:197-201. 2006
    ..No distinct lipid droplets or glycogen particles were identified. The basaloid cells were joined by scattered small desmosomes. These findings were consistent with trichilemmal differentiation at the bulb...
  11. ncbi request reprint An unusual hamartoma of the folliculosebaceous-apocrine unit: a case report
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    J Cutan Pathol 33:365-8. 2006
    ..Some of the epithelial structures were reminiscent of those seen in tubular apocrine adenoma; others resembled syringomatous elements. We interpreted this unusual lesion as a hamartoma of the folliculosebaceous-apocrine unit...
  12. ncbi request reprint Tubular adenoma of the skin with follicular and sebaceous differentiation: A report of two cases
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 28:142-6. 2006
    ..Rare cases occurring in the sites normally devoid of apocrine glands may represent the eccrine counterpart...
  13. ncbi request reprint Melanocytic "ball-in-mitts" and "microalveolar structures" and their role in the development of cellular blue nevi
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, 304 60 Pilsen, Czech Republic
    Ann Diagn Pathol 11:160-75. 2007
    ..These nevi often show a morphological overlap, and ball-in-mitts and microalveolar structures found in various stages of their development seem to greatly account for this overlap...
  14. ncbi request reprint Sebaceous carcinoma arising in nevus sebaceus of Jadassohn: a clinicopathological study of five cases
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 29:242-8. 2007
    ..The rest of organoid nevus is usually recognized both clinically and microscopically, although large tumors may overgrow and mask the nevus. The tumor seems to be a low-grade carcinoma in terms of clinical behavior...
  15. ncbi request reprint Tubular adenoma and syringocystadenoma papilliferum: a reappraisal of their relationship. An interobserver study of a series, by a panel of dermatopathologists
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 29:256-63. 2007
    ....
  16. ncbi request reprint Skin-type hidradenoma of the breast parenchyma with t(11;19) translocation: hidradenoma of the breast
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 29:457-61. 2007
    ..A 120-bp METC1/MAML2 fusion transcript was identified by RT-PCR and subsequent sequencing technique. This t(11;19) translocation has been reported in approximately 50% of hidradenomas of the skin...
  17. doi request reprint High-grade trichoblastic carcinosarcoma
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 30:62-4. 2008
    ..This conclusion is reached after analyzing the embryological development of the hair follicle, its normal histology and the morphology of cutaneous adnexal tumors with follicular differentiation...
  18. ncbi request reprint Human papillomavirus in lesions of anogenital mammary-like glands
    Dmitry V Kazakov
    Sikl s Department of Pathology, Medical Faculty Hospital, Charles University, Pilsen, Czech Republic
    Int J Gynecol Pathol 26:475-80. 2007
    ..These results coupled with those obtained from literature review suggest that HPV plays no causative role in lesions of anogenital MLG...
  19. ncbi request reprint Apocrine mixed tumor of the skin ("mixed tumor of the folliculosebaceous-apocrine complex"). Spectrum of differentiations and metaplastic changes in the epithelial, myoepithelial, and stromal components based on a histopathologic study of 244 cases
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    J Am Acad Dermatol 57:467-83. 2007
    ..A systematic analysis of the entire spectrum of various forms of differentiation and metaplastic epiphenomena in cutaneous apocrine mixed tumor (AMT) has never been performed...
  20. ncbi request reprint Nodular Hyperplasia of the Bartholin Gland: A Clinicopathological Study of Two Cases, Including Detection of Clonality by HUMARA
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 29:385-7. 2007
    ..Clonality analysis performed in one case revealed a monoclonal pattern, suggesting that the lesion may be a neoplastic process rather than simple reactive hyperplasia...
  21. ncbi request reprint Absence of Epstein-Barr virus, human papillomavirus, and simian virus 40 in patients of central european origin with lymphoepithelioma-like carcinoma of the skin
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 29:365-9. 2007
    ..Because all 10 cases studied proved negative for EBV, HPV, and SV40, these viruses seem to play no causal role in LELC of the skin in patients from Central Europe...
  22. doi request reprint Hyperplasia of hair follicles and other adnexal structures in cutaneous lymphoproliferative disorders: a study of 53 cases, including so-called pseudolymphomatous folliculitis and overt lymphomas
    Dmitry V Kazakov
    Sikl Department of Pathology, Medical Military Academy, Saint Petersburg, Russia
    Am J Surg Pathol 32:1468-78. 2008
    ..We conclude that hyperplasia of hair follicles and other adnexa can be seen not only in the condition currently known as PLF, but also in genuine cutaneous lymphomas and may be just a happenstance secondary to a basic pathologic process...
  23. ncbi request reprint Apocrine mixed tumors of the skin with architectural and/or cytologic atypia: a retrospective clinicopathologic study of 18 cases
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Surg Pathol 31:1094-102. 2007
    ..We conclude that some atypical cytoarchitectural features in apocrine mixed tumors, albeit worrisome, do not indicate a malignant change...
  24. ncbi request reprint Morphological variations of scar-related and spontaneous endometriosis of the skin and superficial soft tissue: a study of 71 cases with emphasis on atypical features and types of müllerian differentiations
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    J Am Acad Dermatol 57:134-46. 2007
    ..All patients were women, whose ages ranged from 22 to 65 years (median, 32 years)...
  25. doi request reprint Spiradenoma and spiradenocylindroma with an adenomatous or atypical adenomatous component: a clinicopathological study of 6 cases
    Dmitry V Kazakov
    Sikl s Department of Pathology, Medical Faculty Hospital, Charles University, Pilsen, Czech Republic
    Am J Dermatopathol 30:436-41. 2008
    ..Three cases also manifested clear cell areas. Immunohistochemical studies demonstrated that myoepithelial proliferation and overgrowth accounted for the clear cell change in some of the lesions...
  26. ncbi request reprint Unusual hyperplasia of anogenital mammary-like glands
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 28:134-7. 2006
    ..In addition, there were adenosis-like areas. This lesion extends the spectrum of changes seen in anogenital mammary-like glands...
  27. doi request reprint Mutations in exon 3 of the CTNNB1 gene (beta-catenin gene) in cutaneous adnexal tumors
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 31:248-55. 2009
    ..This study broadens the list of cutaneous adnexal tumors harboring CTNNB1 mutations and extends the listing of the mutations occurring in these neoplasms...
  28. doi request reprint Cutaneous type adnexal tumors outside the skin
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Alej Svobody 80, Pilsen, Czech Republic
    Am J Dermatopathol 33:303-15. 2011
    ..This review discusses various authentic cutaneous-type adnexal neoplasms or related lesions presented according to the organ involved...
  29. doi request reprint Vulvar syringomas with deep extension: a potential histopathologic mimic of microcystic adnexal carcinoma
    Dmitry V Kazakov
    Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Int J Gynecol Pathol 30:92-4. 2011
    ..We present a case of multiple vulvar syringomas, some of which extended unusually deep into the dermis occasioning histopathologic resemblance to microcystic adnexal carcinoma. The pertinent literature is discussed...
  30. doi request reprint Hyperplasia of ectopic sebaceous glands in the uterine cervix: case report
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Int J Gynecol Pathol 29:605-8. 2010
    ..In one area, there were over 20 sebaceous lobules that were partly connected to a sebaceous duct. To our knowledge, similar changes in ectopic sebaceous glands in the uterine cervix have not been reported till date...
  31. doi request reprint Lesions of anogenital mammary-like glands: an update
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Alej Svobody 80, Pilsen, Czech Republic
    Adv Anat Pathol 18:1-28. 2011
    ..This will enable their recognition, precise classification and should introduce greater uniformity in how they are reported in the literature so that more meaningful clinicopathological comparisons and correlations may be made...
  32. ncbi request reprint Cutaneous adenolipoma: extending the spectrum of changes in the lipomatous and epithelial components
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 33:56-9. 2011
    ....
  33. doi request reprint Microcystic adnexal carcinoma with multiple areas of follicular differentiation toward germinative cells and specific follicular stroma (trichoblastomatous areas)
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 33:e47-9. 2011
    ..We also reviewed 24 cases of MAC in our files, but in none of the cases were similar features observed, indicating that such histopathological findings are rare in MAC...
  34. doi request reprint Multiple (familial) trichoepitheliomas: a clinicopathological and molecular biological study, including CYLD and PTCH gene analysis, of a series of 16 patients
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Alej Svobody 80, Pilsen, Czech Republic
    Am J Dermatopathol 33:251-65. 2011
    ..Considering our 5 patients with no mutation in either gene, the final possibility is that another, as yet undescribed gene (neither CYLD nor PTCH) is implicated in the pathogenesis of some patients with MFT...
  35. doi request reprint Cutaneous mixed tumor, eccrine variant: a clinicopathologic and immunohistochemical study of 50 cases, with emphasis on unusual histopathologic features
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 33:557-68. 2011
    ..Most of these features have not been previously recorded in eccrine mixed tumors and may represent a potential diagnostic pitfall...
  36. doi request reprint A cutaneous adnexal neoplasm with features of adamantinoid trichoblastoma (lymphadenoma) in the benign component and lymphoepithelial-like carcinoma in the malignant component: a possible case of malignant transformation of a rare trichoblastoma variant
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 33:729-32. 2011
    ..This seems to be the first documented report of malignant transformation of adamantinoid trichoblastoma. We discuss also other possibilities of histogenesis of this unique neoplasm...
  37. doi request reprint Prostatic-type tissue in the lower female genital tract: a morphologic spectrum, including vaginal tubulosquamous polyp, adenomyomatous hyperplasia of paraurethral Skene glands (female prostate), and ectopic lesion in the vulva
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Surg Pathol 34:950-5. 2010
    ..All lesions were immunopositive for prostate-specific antigen and/or prostatic acid phosphatase. A brief discussion of the earlier published material is included...
  38. ncbi request reprint Morphologic diversity of syringocystadenocarcinoma papilliferum based on a clinicopathologic study of 6 cases and review of the literature
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 32:340-7. 2010
    ..Its association with the benign counterpart and ductal changes suggests a transformation that may involve usual ductal hyperplasia-atypical ductal hyperplasia-(ductal) adenocarcinoma in situ-invasive adenocarcinoma pathway...
  39. doi request reprint Skin type spiradenoma of the parotid gland with malignant transformation: report of a case with analysis of the CYLD gene
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Hum Pathol 40:1499-503. 2009
    ..Analysis of the CYLD gene revealed polymorphisms. This is the first report of a "dermal analogue tumor" of the salivary gland that resembled a cutaneous spiradenoma and not a cylindroma...
  40. ncbi request reprint A case of Brooke-Spiegler syndrome with a novel germline deep intronic mutation in the CYLD gene leading to intronic exonization, diverse somatic mutations, and unusual histology
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 31:664-73. 2009
    ..A deep intronic mutation resulting in exonization and a somatic sequence mutations causing exon skipping are hitherto unreported genetic mechanisms involving the CYLD gene in patients with Brooke-Spiegler syndrome...
  41. ncbi request reprint Adenosis tumor of anogenital mammary-like glands: a case report and demonstration of clonality by HUMARA assay
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    J Cutan Pathol 33:43-6. 2006
    ..This cutaneous perianal lesion is indistinguishable microscopically from its mammary analogue and was clinically detectable...
  42. ncbi request reprint Spectrum of tumors with follicular differentiation in a patient with the clinical phenotype of multiple familial trichoepitheliomas: a clinicopathological and molecular biological study, including analysis of the CYLD and PTCH genes
    Dmitry V Kazakov
    Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 31:819-27. 2009
    ....
  43. doi request reprint Fibroadenoma and phyllodes tumors of anogenital mammary-like glands: a series of 13 neoplasms in 12 cases, including mammary-type juvenile fibroadenoma, fibroadenoma with lactation changes, and neurofibromatosis-associated pseudoangiomatous stromal hyperp
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Czech Republic
    Am J Surg Pathol 34:95-103. 2010
    ....
  44. ncbi request reprint Dendritic cell neurofibroma with pseudorosettes lacks mutations in exons 1-15 of the neurofibromatosis type 2 gene
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 27:286-9. 2005
    ....
  45. ncbi request reprint Pseudoangiomatous stromal hyperplasia in lesions involving anogenital mammary-like glands
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Surg Pathol 29:1243-6. 2005
    ..The clinicopathologic features of PASH in the anogenital area seem to be identical to those in the breast...
  46. doi request reprint Expression of p53 and TP53 mutational analysis in malignant neoplasms arising in preexisting spiradenoma, cylindroma, and spiradenocylindroma, sporadic or associated with Brooke-Spiegler syndrome
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 32:215-21. 2010
    ....
  47. ncbi request reprint Brooke-Spiegler syndrome: report of a case with a novel mutation in the CYLD gene and different types of somatic mutations in benign and malignant tumors
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    J Cutan Pathol 37:886-90. 2010
    ..2322delA causing a frameshift mutation E774DfsX2. LOH occurred in both BCCs, one trichoepithelioma and one spiradenoma. In the remaining three lesions, the somatic event remained undetected...
  48. ncbi request reprint Trichoepithelioma with giant and multinucleated neoplastic epithelial cells
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 28:63-4. 2006
    ..CD34 stained the stroma. We believe that the focal presence of pleomorphic giant cells in trichoepithelioma has no clinical or prognostic implications and does not denote its "malignant transformation"...
  49. ncbi request reprint Hybrid peripheral nerve sheath tumors: Schwannoma-perineurioma and neurofibroma-perineurioma. A report of three cases in extradigital locations
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, 30460 Pilsen, Czech Republic
    Ann Diagn Pathol 9:16-23. 2005
    ..An ultrastructural study was performed in one case of neurofibroma-perineurioma. All cases were studied for mutation of the NF2 gene, and in one case (neurofibroma-perineurioma) a point mutation was detected in exon 15 of the gene...
  50. doi request reprint Novel and recurrent germline and somatic mutations in a cohort of 67 patients from 48 families with Brooke-Spiegler syndrome including the phenotypic variant of multiple familial trichoepitheliomas and correlation with the histopathologic findings in 379
    Petr Grossmann
    Bioptical Laboratory, Pilsen, Czech Republic
    Am J Dermatopathol 35:34-44. 2013
    ..We confirm the absence of firm genotype-phenotype correlations and the existence of a subset of patients with BSS/MFT who lack a demonstrable germline CYLD mutation. Further studies are needed to explain the reasons for this phenomenon...
  51. ncbi request reprint Hidradenoma papilliferum with oxyphilic metaplasia: a clinicopathological study of 18 cases, including detection of human papillomavirus
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 27:102-10. 2005
    ..A causal role for HPV in hidradenoma papilliferum cannot be confirmed from our results, as the detection rate is too low. The exact role of the HPV in etiology and pathogenesis of this neoplasm has yet to be determined...
  52. doi request reprint Spiradenocylindroma-like basaloid carcinoma of the anus and rectum: case report, including HPV studies and analysis of the CYLD gene mutations
    Denisa Kacerovska
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 30:472-6. 2008
    ..A molecular biology study identified HPV-16 in the lesional tissue. Analysis of the CYLD gene did not prove any mutation...
  53. doi request reprint A clinicopathologic and molecular biologic study of patients presenting with few adnexal tumors (two to four) from the morphological spectrum of Brooke-Spiegler syndrome
    Denisa Kacerovska
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 35:19-24. 2013
    ..It is concluded that the presentation with few (2-4) cylindromas, spiradenomas, spiradenocylindromas, and trichoepitheliomas is a sporadic occurrence, and that these patients do not have any relationship to BSS...
  54. ncbi request reprint Brooke-Spiegler syndrome: report of a case with combined lesions containing cylindromatous, spiradenomatous, trichoblastomatous, and sebaceous differentiation
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 27:27-33. 2005
    ..The occurrence of sebaceous and trichoblastic differentiation in spiradenocylindromas is a further proof that spiradenoma and cylindroma are not eccrine tumors but neoplasms of the folliculosebaceousapocrine unit...
  55. ncbi request reprint Reactive syringofibroadenomatous hyperplasia in peristomal skin with formation of hybrid epidermal-colonic mucosa glandular structures, intraepidermal areas of sebaceous differentiation, induction of hair follicles, and features of human papillomavirus in
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 27:135-41. 2005
    ..The rudimentary follicles and sebaceous differentiation were probably induced by an altered stroma and/or human papillomavirus (HPV): HPV, type 36 was identified by PCR using consensus primers followed by sequencing of the PCR products...
  56. ncbi request reprint Cutaneous lymphoid hyperplasia and other lymphoid infiltrates of the breast nipple: a retrospective clinicopathologic study of fifty-six patients
    Ludmila Boudova
    Department of Pathology, Medical Faculty Hospital, Charles University, Pilsen, Czech Republic
    Am J Dermatopathol 27:375-86. 2005
    ..We conclude that cutaneous lymphoid hyperplasia is the most common lymphoproliferation of the breast nipple, rarely recognized clinically, and often overdiagnosed histologically as lymphoma...
  57. ncbi request reprint Adenoid cystic carcinoma-like pattern in spiradenoma and spiradenocylindroma: a rare feature in sporadic neoplasms and those associated with Brooke-Spiegler syndrome
    Fredrik Petersson
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 31:642-8. 2009
    ..It represents a potential diagnostic pitfall, particularly in a limited biopsy specimen where the changes may be misdiagnosed as ACC...
  58. ncbi request reprint Mucinous carcinoma of the skin, primary, and secondary: a clinicopathologic study of 63 cases with emphasis on the morphologic spectrum of primary cutaneous forms: homologies with mucinous lesions in the breast
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Alej Svobody 80, 304 60 Pilsen, Czech Republic
    Am J Surg Pathol 29:764-82. 2005
    ..Dirty necrosis was a constant histologic finding in intestine mucinous carcinomas involving the skin, and this feature may serve as a clue to an intestinal origin...
  59. ncbi request reprint Spectrum of cutaneous and soft tissue lesions in two Carney complex patients-adnexal induction versus authentic adnexal neoplasms
    Denisa Kacerovska
    Department of Pathology, Medical Faculty in Pilsen, Charles University in Prague, Pilsen, Czech Republic
    Am J Dermatopathol 34:729-36. 2012
    ....
  60. ncbi request reprint Benign schwannoma with perineurioma-like areas: A clinicopathologic study of 11 cases
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Int J Surg Pathol 14:320-5. 2006
    ..These neoplasms represent a morphologic variant of schwannoma having distinctive perineurial-like areas, a pattern which may elicit diagnostic difficulties...
  61. ncbi request reprint Cutaneous sebaceous neoplasms with a focal glandular pattern (seboapocrine lesions): a clinicopathological study of three cases
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 29:359-64. 2007
    ..These tumors may be viewed as rare histopathological variants of sebaceous carcinoma and sebaceoma, with a second type of differentiation along the lines of the folliculosebaceous-apocrine unit...
  62. ncbi request reprint Carcinoid-like pattern in sebaceous neoplasms: another distinctive, previously unrecognized pattern in extraocular sebaceous carcinoma and sebaceoma
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 27:195-203. 2005
    ..This pattern seems to be closely related to the rippled and labyrinthine/sinusoidal patterns, as exemplified by our cases, in which these arrangements sometimes occurred simultaneously...
  63. ncbi request reprint Primary cutaneous histiocyte and neutrophil-rich CD30+ and CD56+ anaplastic large-cell lymphoma with prominent angioinvasion and nerve involvement in the forehead and scalp of an immunocompetent woman
    Ludmila Boudova
    Department of Pathology, Medical Faculty Hospital, Charles University, Pilsen, Czech Republic
    J Cutan Pathol 33:584-9. 2006
    ..They share a clinicopathological overlap with natural killer- (NK)/T-cell lymphomas and anaplastic large-cell lymphomas (ALCLs), two entities with widely disparate clinical behavior...
  64. doi request reprint Crystal-deficient alveolar soft-part sarcoma with cutaneous involvement: a case report
    Denisa Kacerovska
    Sikl s Department of Pathology, Charles University Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 31:272-7. 2009
    ..Molecular genetic study revealed fusion transcript ASPL-TFE3, type 2. To the best of our knowledge, cutaneous involvement of a crystal-deficient ASPS has not been reported...
  65. ncbi request reprint Primary intranodal cellular angiolipoma
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Int J Surg Pathol 13:99-101. 2005
    ..As we present in this report, angiolipoma is another neoplasm whose primary occurrence in the lymph node should not be misinterpreted as a metastatic tumor or malignant vascular tumor...
  66. ncbi request reprint Follicular lymphoma of the skin and superficial soft tissues associated with a prominent follicular dendritic cell proliferation: an unusual pattern which may represent a diagnostic pitfall
    Dmitry V Kazakov
    Laboratoire Spec Diagnostiky, Sikl s Department of Pathology, Medical Faculty Hospital, Charles University, Alej Svobody 80, 30460 Pilsen, Czech Republic
    Pathol Res Pract 200:557-65. 2004
    ..Such cases may represent a diagnostic pitfall, as FDC overgrowth can mask FL and give the neoplasm the appearance of FDC sarcoma/tumor. We believe that, in both cases, the FDC proliferation had a reactive character...
  67. ncbi request reprint Primitive small cell tumor with epithelial, gangliocytic, neuroendocrine, and mesenchymal differentiation: report of 2 cases
    Michal Michal
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Alej Svobody 80, 304 60 Pilsen, Czech Republic
    Int J Surg Pathol 15:429-36. 2007
    ..Granules were found in the cytoplasm. We suggest the name "primitive small cell tumor with epithelial, gangliocytic, neuroendocrine, and mesenchymal differentiation" for this neoplasm...
  68. ncbi request reprint Low-grade trichoblastic carcinosarcoma of the skin
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 26:304-9. 2004
    ..There were also a high number of p53-positive cells in both compartments. We propose the term "low-grade trichoblastic carcinosarcoma" for this neoplasm. We are not aware of a similar tumor published in the English literature...
  69. ncbi request reprint Hemosiderotic fibrohistiocytic lipomatous lesion: clinical correlation with venous stasis
    Dmitry V Kazakov
    Sikl s Department of Pathology, Medical Faculty Hospital, Charles University, Alej Svobody 80, 304 60, Pilsen, Czech Republic
    Virchows Arch 447:103-6. 2005
    ..A similar histopathological pattern is seen in acroangiodermatitis of Mali and vascular transformation of lymph node sinuses, and these conditions are also associated with impaired blood circulation...
  70. ncbi request reprint A benign neoplasm with histopathological features of both schwannoma and retiform perineurioma (benign schwannoma-perineurioma): a report of six cases of a distinctive soft tissue tumor with a predilection for the fingers
    Michal Michal
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Alej Svobody 80, 30460 Pilsen, Czech Republic
    Virchows Arch 445:347-53. 2004
    ..We interpreted the lesions as hybrid tumors with features of schwannoma and retiform perineurioma...
  71. doi request reprint Ovarian fibromas with heavy deposition of hyaline globules: a diagnostic pitfall
    Michal Michal
    Sikl s Department of Pathology, Bioptical Laboratory sro, Charles University Hospital, Pilsen, Czech Republic
    Int J Gynecol Pathol 28:356-61. 2009
    ..Follow-up in one of the patients was not available. The distinction of the ovarian fibromas with hyaline globules from the Krukenberg tumors and yolk sac tumor is discussed in the paper...
  72. ncbi request reprint Branchial-like cysts of the thyroid associated with solid cell nests
    Michal Michal
    Sikl s Department of Pathology, Charles University, Pilsen, Czech Republic
    Pathol Int 56:150-3. 2006
    ..Immunohistochemically, all lesional elements were negative for calcitonin and thyroglobulin. The results of the paper suggest that branchial cleft-like cyst have an origin in the ultimobranchial body...
  73. doi request reprint End-stage kidney disease: gains of chromosomes 7 and 17 and loss of Y chromosome in non-neoplastic tissue
    Ondrej Hes
    Department of Pathology, Faculty of Medicine Plzen, Charles University Prague, Plzen, Czech Republic
    Virchows Arch 453:313-9. 2008
    ..e., trisomies of chromosomes 7 and 17, are very frequent in non-neoplastic parenchyma of the end-stage kidney, and they have a tendency to a multifocal occurrence...
  74. doi request reprint Mesothelial glandular structures within pseudosarcomatous proliferative funiculitis--a diagnostic pitfall: report of 17 cases
    Michal Michal
    Sikl s Department of Pathology, Laboratore Spec Diagnostiky Medical Faculty Hospital, Plzen, Czech Republic
    Int J Surg Pathol 16:48-56. 2008
    ....
  75. ncbi request reprint Mixed germ cell sex cord-stromal tumors of the testis and ovary. Morphological, immunohistochemical, and molecular genetic study of seven cases
    Michal Michal
    Sikl s Department of Pathology, Charles University Hospital, Pilsen, Czech Republic
    Virchows Arch 448:612-22. 2006
    ..All other germ cells were negative for amplification of 12p. All five successfully analyzed cases showed no mutation in all studied exons and exon-intron junctions in c-kit and PDFGRA genes...
  76. ncbi request reprint Primary signet-ring stromal tumor of the testis
    Michal Michal
    Department of Pathology, University Hospital Plzen, Pilsen, Czech Republic
    Virchows Arch 447:107-10. 2005
    ..The signet-ring stromal tumor of the testis is thus similar morphologically and immunohistochemically to the signet-ring stromal tumor of the ovary. The patient was free of recurrence and metastasis 3 years after the excision...
  77. ncbi request reprint Extracutaneous transformation into a high-grade lymphoma: a potential pitfall in the management of patients with Sézary syndrome
    Sonja Michaelis
    Department of Dermatology, University Hospital, Zurich, Switzerland
    Int J Dermatol 45:277-9. 2006
    ..Transformation into a high-grade lymphoma in cutaneous T-cell lymphoma (CTCL) occurs in approximately 25% of cases and is associated with an aggressive clinical course...
  78. doi request reprint Hybrid neurofibroma-perineurioma: an additional example of an extradigital tumor
    Ksenya V Shelekhova
    Ann Diagn Pathol 12:233-4. 2008
  79. ncbi request reprint Melanoma with prominent pigment synthesis (animal-type melanoma): a case report with ultrastructural studies
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 26:290-7. 2004
    ..Melanophages were a minor component of the lesion. Our ultrastructural studies provide unequivocal evidence that ATM is a neoplasm of melanosome-producing cells. We also review the literature on ATM...
  80. doi request reprint Vascular changes in merkel cell carcinoma based on a histopathological study of 92 cases
    Marina Vazmitel
    Academy of Postgraduate Education of Belarus, Minsk, Republic of Belarus
    Am J Dermatopathol 30:106-11. 2008
    ..Human herpesvirus 8 does not play a role in angiogenesis in MCC...
  81. ncbi request reprint Intraneural dendritic cell neurofibroma with pseudorosettes
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 26:72-5. 2004
    ..This observation gives further evidence that this entity is a peripheral nerve sheath tumor and is unrelated to melanocytic neoplasms...
  82. doi request reprint Syringocystadenoma papilliferum with sebaceous differentiation in an intradermal tubular apocrine component. Report of a case
    Marina Vazmitel
    Department of Pathology, Academy of Postgraduate Studies, Minsk, Republic of Belarus
    Am J Dermatopathol 30:51-3. 2008
    ....
  83. ncbi request reprint Cutaneous lymphomas and pseudolymphomas: newly described entities
    Dmitry V Kazakov
    Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland
    Recent Results Cancer Res 160:283-93. 2002
    ..In the context of pseudolymphomas, cutaneous follicular lymphoid hyperplasia with monotypic plasma cells, pleomorphic reactions in molluscum contagiosum, and CD30+ reactions to parapoxvirus are discussed...
  84. doi request reprint Merkel cell carcinoma with a follicular lymphocytic infiltrate: report of 2 cases
    Marina Vazmitel
    Academy of Medical Postgraduate Education of Belarus, Minsk, Republic of Belarus
    Am J Dermatopathol 30:389-91. 2008
    ..We present here 2 cases of MCC characterized by foci of a dense lymphocytic infiltrate with the formation of lymphoid follicles. This feature may produce a potential diagnostic pitfall, rendering a lymphomatous appearance to the tumor...
  85. doi request reprint Hidradenoma papilliferum with a ductal carcinoma in situ component: case report and review of the literature
    Marina Vazmitel
    Department of Pathology, Academy of Medical Postgraduate Education of Belarus, Minsk, Republic of Belarus
    Am J Dermatopathol 30:392-4. 2008
    ..Molecular biological study identified human papillomavirus (HPV)-16, which, it may be argued, may have played a role in the development of the carcinoma...
  86. doi request reprint Atypical histopathological features in cutaneous lymphoid hyperplasia of the scrotum
    Irena E Belousova
    Am J Dermatopathol 30:407-8. 2008
  87. ncbi request reprint Myxoid dermatofibrosarcoma protuberans: clinicopathologic, immunohistochemical, and molecular analysis of eight cases
    Thomas Mentzel
    Dermatopathologische Gemeinschaftspraxis, Friedrichshafen, Germany
    Am J Dermatopathol 29:443-8. 2007
    ....
  88. ncbi request reprint Melanoma associated with a dysplastic nevus: report of two cases with unusual sebocyte-like melanocytes in the nevus part of the lesion
    Marina Vazmitel
    Academy of Postgraduate Education of Belarus, Minsk, Republic of Belarus
    Am J Dermatopathol 29:566-7. 2007
    ..The cases are discussed in the context of the pertinent literature...
  89. ncbi request reprint A patient with clinicopathologic features of small plaque parapsoriasis presenting later with plaque-stage mycosis fungoides: report of a case and comparative retrospective study of 27 cases of "nonprogressive" small plaque parapsoriasis
    Irena E Belousova
    Department of Dermatology and Venereology, Medical Military Academy, Saint Petersburg, Russia
    J Am Acad Dermatol 59:474-82. 2008
    ..The literature contains no fully documented example of progression of SPP into MF...
  90. ncbi request reprint Merkel cell carcinoma and Azzopardi phenomenon
    Marina Vazmitel
    Am J Dermatopathol 29:314-5. 2007
  91. ncbi request reprint Detection of clonal rearrangement of T-cell receptor genes in the diagnosis of primary cutaneous CD30 lymphoproliferative disorders
    Johannes Greisser
    Department of Dermatology, University Hospital, Zurich, Switzerland
    J Cutan Pathol 33:711-5. 2006
    ....
  92. ncbi request reprint Sarcoma arising in hyaline-vascular castleman disease of skin and subcutis
    Dmitry V Kazakov
    Sikl s Department of Pathology, Charles University, Medical Faculty Hospital, Pilsen, Czech Republic
    Am J Dermatopathol 27:327-32. 2005
    ..The sarcomatous component in this case is most consistent with a poorly differentiated follicular dendritic cell sarcoma based upon the morphologic and ultrastructural findings...
  93. ncbi request reprint Primary cutaneous plasmacytoma: a clinicopathological study of two cases with a long-term follow-up and review of the literature
    Dmitry V Kazakov
    Department of Dermatology, University Hospital, Zurich, Switzerland
    J Cutan Pathol 29:244-8. 2002
    ..The disease is rare with only 30 cases reported so far...
  94. ncbi request reprint The anti-MAGE antibody B57 as a diagnostic marker in melanocytic lesions
    Dmitry V Kazakov
    Unit of Dermatopathology, Department of Dermatology, University Hospital, Zurich, Switzerland
    Am J Dermatopathol 26:102-7. 2004
    ....