Robert Jech

Summary

Affiliation: Charles University
Country: Czech Republic

Publications

  1. pmc The subthalamic microlesion story in Parkinson's disease: electrode insertion-related motor improvement with relative cortico-subcortical hypoactivation in fMRI
    Robert Jech
    Dept of Neurology and Center of Clinical Neuroscience, Charles University in Prague, 1st Faculty of Medicine and General University Hospital, Prague, Czech Republic
    PLoS ONE 7:e49056. 2012
  2. doi request reprint Cortical pattern of complex but not simple movements is affected in writer's cramp: a parametric event-related fMRI study
    Petra Havrankova
    Dept of Neurology and Center of Clinical Neuroscience, Charles University in Prague, 1st Faculty of Medicine and General University Hospital, Prague, Czech Republic
    Clin Neurophysiol 123:755-63. 2012
  3. doi request reprint Subthalamic nucleus stimulation affects incentive salience attribution in Parkinson's disease
    Tereza Serranova
    Department of Neurology and Center of Clinical Neuroscience, Charles University in Prague, 1st Faculty of Medicine and General University Hospital, Prague, Czech Republic
    Mov Disord 26:2260-6. 2011
  4. pmc Abnormal activity in the precuneus during time perception in Parkinson's disease: an fMRI study
    Petr Dusek
    Department of Neurology and Center of Clinical Neuroscience, Charles University in Prague, 1st Faculty of Medicine and General University Hospital, Prague, Czech Republic
    PLoS ONE 7:e29635. 2012
  5. pmc Weight gain is associated with medial contact site of subthalamic stimulation in Parkinson's disease
    Filip Ruzicka
    Department of Neurology and Centre of Clinical Neuroscience, First Faculty of Medicine and General University Hospital, Charles University, Prague, Czech Republic
    PLoS ONE 7:e38020. 2012
  6. ncbi request reprint MR relaxometry in Huntington's disease: correlation between imaging, genetic and clinical parameters
    Josef Vymazal
    Department of MRI, Na Homolce Hospital, Prague, Czech Republic
    J Neurol Sci 263:20-5. 2007
  7. ncbi request reprint Hormonal regulators of food intake and weight gain in Parkinson's disease after subthalamic nucleus stimulation
    Lucie Novakova
    Department of Neurology and Centre of Clinical Neuroscience, Charles University, Prague, Czech Republic
    Neuro Endocrinol Lett 32:437-41. 2011
  8. doi request reprint Sex, food and threat: startling changes after subthalamic stimulation in Parkinson's disease
    Tereza Serranova
    Department of Neurology and Center of Clinical Neuroscience, Charles University in Prague, 1st Faculty of Medicine and General University Hospital, Prague, Czech Republic Electronic address
    Brain Stimul 6:740-5. 2013
  9. ncbi request reprint Increase in body weight is a non-motor side effect of deep brain stimulation of the subthalamic nucleus in Parkinson's disease
    Lucie Novakova
    Movement Disorders Center, Department of Neurology, Charles University, Prague, Czech Republic
    Neuro Endocrinol Lett 28:21-5. 2007
  10. doi request reprint Sleep disturbances in untreated Parkinson's disease
    Jitka Buskova
    First Faculty of Medicine, Department of Neurology, Centre of Clinical Neuroscience, General University Hospital in Prague, Charles University in Prague, Katerinska 30, 128 21, Prague 2, Czech Republic
    J Neurol 258:2254-9. 2011

Collaborators

Detail Information

Publications19

  1. pmc The subthalamic microlesion story in Parkinson's disease: electrode insertion-related motor improvement with relative cortico-subcortical hypoactivation in fMRI
    Robert Jech
    Dept of Neurology and Center of Clinical Neuroscience, Charles University in Prague, 1st Faculty of Medicine and General University Hospital, Prague, Czech Republic
    PLoS ONE 7:e49056. 2012
    ..The motor system finally adapted to the microlesion within one month as suggested by loss of motor improvement and good efficacy of deep brain stimulation...
  2. doi request reprint Cortical pattern of complex but not simple movements is affected in writer's cramp: a parametric event-related fMRI study
    Petra Havrankova
    Dept of Neurology and Center of Clinical Neuroscience, Charles University in Prague, 1st Faculty of Medicine and General University Hospital, Prague, Czech Republic
    Clin Neurophysiol 123:755-63. 2012
    ..Patients with writer's cramp (WC) were studied for differences in cortical activation during movements likely to induce WC (complex movements) and movements which rarely lead to dystonia (simple movements)...
  3. doi request reprint Subthalamic nucleus stimulation affects incentive salience attribution in Parkinson's disease
    Tereza Serranova
    Department of Neurology and Center of Clinical Neuroscience, Charles University in Prague, 1st Faculty of Medicine and General University Hospital, Prague, Czech Republic
    Mov Disord 26:2260-6. 2011
    ..In addition, STN DBS-related sensitivity to food reward stimuli cues might drive DBS-treated patients to higher food intake and subsequent weight gain...
  4. pmc Abnormal activity in the precuneus during time perception in Parkinson's disease: an fMRI study
    Petr Dusek
    Department of Neurology and Center of Clinical Neuroscience, Charles University in Prague, 1st Faculty of Medicine and General University Hospital, Prague, Czech Republic
    PLoS ONE 7:e29635. 2012
    ..This deficit improves after dopamine (DA) treatment and it has been associated with decreased internal timekeeper speed, disruption of executive function and memory retrieval dysfunction...
  5. pmc Weight gain is associated with medial contact site of subthalamic stimulation in Parkinson's disease
    Filip Ruzicka
    Department of Neurology and Centre of Clinical Neuroscience, First Faculty of Medicine and General University Hospital, Charles University, Prague, Czech Republic
    PLoS ONE 7:e38020. 2012
    ....
  6. ncbi request reprint MR relaxometry in Huntington's disease: correlation between imaging, genetic and clinical parameters
    Josef Vymazal
    Department of MRI, Na Homolce Hospital, Prague, Czech Republic
    J Neurol Sci 263:20-5. 2007
    ..An increase in "toxic" iron in the caudate may enable oxidative stress and thus underlie progression of the disease...
  7. ncbi request reprint Hormonal regulators of food intake and weight gain in Parkinson's disease after subthalamic nucleus stimulation
    Lucie Novakova
    Department of Neurology and Centre of Clinical Neuroscience, Charles University, Prague, Czech Republic
    Neuro Endocrinol Lett 32:437-41. 2011
    ..Weight gain has been reported in patients with Parkinson's disease (PD) treated with deep brain stimulation of the subthalamic nucleus (STN-DBS). To evaluate the influence of STN-DBS on weight changes, we studied food-related hormones...
  8. doi request reprint Sex, food and threat: startling changes after subthalamic stimulation in Parkinson's disease
    Tereza Serranova
    Department of Neurology and Center of Clinical Neuroscience, Charles University in Prague, 1st Faculty of Medicine and General University Hospital, Prague, Czech Republic Electronic address
    Brain Stimul 6:740-5. 2013
    ..Changes in motivational processing may play a role in weight gain and other non-motor side effects in Parkinson's disease (PD) patients treated with deep brain stimulation of the subthalamic nucleus...
  9. ncbi request reprint Increase in body weight is a non-motor side effect of deep brain stimulation of the subthalamic nucleus in Parkinson's disease
    Lucie Novakova
    Movement Disorders Center, Department of Neurology, Charles University, Prague, Czech Republic
    Neuro Endocrinol Lett 28:21-5. 2007
    ..Possible explanations of body weight gain after DBS STN include a reduction of energy output related to elimination of dyskinesias, improved alimentation or direct influence on function of lateral hypothalamus by DBS STN...
  10. doi request reprint Sleep disturbances in untreated Parkinson's disease
    Jitka Buskova
    First Faculty of Medicine, Department of Neurology, Centre of Clinical Neuroscience, General University Hospital in Prague, Charles University in Prague, Katerinska 30, 128 21, Prague 2, Czech Republic
    J Neurol 258:2254-9. 2011
    ..65, p < 0.05). This study demonstrates that sleep disturbances emerge, in a proportion of patients, from the early stages of PD. RWA is a common finding while RBD is rarely present in early untreated PD...
  11. ncbi request reprint Variation of selective gray and white matter atrophy in Huntington's disease
    Robert Jech
    Movement Disorders Center, Department of Neurology, 1st Medical Faculty, Charles University, Prague, Czech Republic
    Mov Disord 22:1783-9. 2007
    ..According to our results, the genetic load in HD predicts partially the extent of selective gray/white brain matter atrophy, which is then reflected in the severity of motor impairment...
  12. doi request reprint Disorders of balance and gait in essential tremor are associated with midline tremor and age
    Martina Hoskovcová
    Department of Neurology and Centre of Clinical Neuroscience, First Faculty of Medicine and General University Hospital in Prague, Charles University in Prague, Katerinska 30, Prague, 128 21, Czech Republic
    Cerebellum 12:27-34. 2013
    ..In conclusion, gait and balance alterations in ET patients occur even without subjective complaints. Their relationship with midline tremor and dependence on age suggest a connection with cerebellar dysfunction...
  13. pmc A loud auditory stimulus overcomes voluntary movement limitation in cervical dystonia
    Tereza Serranova
    Department of Neurology and Centre of Clinical Neuroscience, 1st Medical Faculty, Charles University in Prague, Prague, Czech Republic
    PLoS ONE 7:e46586. 2012
    ..We expected that CD patients would show an abnormal StartReact phenomenon...
  14. ncbi request reprint Repetitive TMS of the somatosensory cortex improves writer's cramp and enhances cortical activity
    Petra Havrankova
    Department of Neurology, 1st Medical Faculty and General Teaching Hospital, Charles University, Prague, Czech Republic
    Neuro Endocrinol Lett 31:73-86. 2010
    ..The beneficial effects of rTMS paralleled the functional reorganization in the SI cortex and connected areas, reflecting the impact of somatosensory system on active motion control...
  15. ncbi request reprint Theta-burst transcranial magnetic stimulation over the supplementary motor area decreases variability of temporal estimates
    Petr Dusek
    Department of Neurology, Charles University, Prague, Czech Republic
    Neuro Endocrinol Lett 32:481-6. 2011
    ..The aim of this study was to support this hypothesis by influencing time estimates with theta burst transcranial magnetic stimulation (TMS) over the SMA...
  16. doi request reprint Effects of ropinirole prolonged-release on sleep disturbances and daytime sleepiness in Parkinson disease
    Petr Dusek
    Department of Neurology, Charles University in Prague, 1st Faculty of Medicine and General Teaching Hospital, Praha, Czech Republic
    Clin Neuropharmacol 33:186-90. 2010
    ..Ropinirole prolonged-release compared with RIR improved subjective quality of sleep, reduced daytime sleepiness, and led to disappearance of SAs in some patients possibly due to a more stable plasma level of ropinirole...
  17. ncbi request reprint VIM thalamic stimulation for tremor in a patient with IgM paraproteinaemic demyelinating neuropathy
    Evzen Ruzicka
    Movement Disorders Centre, 1st Medical Faculty, Charles University, Prague, Czech Republic
    Mov Disord 18:1192-5. 2003
    ..We demonstrate the effect of deep brain stimulation of the ventral intermediate thalamic nucleus on intractable action tremor, in a 72-year-old man suffering from neuropathy associated with monoclonal gammopathy...
  18. doi request reprint Quantitative brain MR imaging in amyotrophic lateral sclerosis
    Jiri Keller
    Third Faculty of Medicine, Charles University in Prague, Prague, Czech Republic
    MAGMA 24:67-76. 2011
    ..To evaluate the potential of quantitative MR techniques [voxel-based morphometry (VBM), T2-relaxometry, mean diffusivity (MD), fractional anisotropy (FA)] in the diagnostics of amyotrophic lateral sclerosis (ALS)...
  19. ncbi request reprint Caudate nucleus atrophy in Huntington's disease and its relationship with clinical and genetic parameters
    Jan Roth
    Department of Neurology, 1st Medical Faculty, Charles University, Prague, Czech Republic
    Funct Neurol 20:127-30. 2005
    ..Moreover, the type of inheritance did not influence the age at onset of HD in our patients. Planimetric measurement of the HCN appears to be a simple and useful paraclinical tool for the diagnosis of HD...