Cyril Hoschl

Summary

Affiliation: Charles University
Country: Czech Republic

Publications

  1. doi request reprint European psychiatry: needs, challenges and structures
    Cyril Hoschl
    Prague Psychiatric Centre, 3rd Faculty of Medicine, Charles University, Ustavni 91, 181 03 Praha 8, Czech Republic
    Eur Arch Psychiatry Clin Neurosci 259:S119-22. 2009
  2. pmc The media and intellectuals' response to medical publications: the antidepressants' case
    Konstantinos N Fountoulakis
    3rd Department of Psychiatry, School of Medicine, Aristotle University of Thessaloniki, 54636, Thessaloniki, Greece
    Ann Gen Psychiatry 12:11. 2013
  3. doi request reprint The state of psychiatry in the Czech Republic
    Cyril Hoschl
    Prague Psychiatric Centre, Prague, Czech Republic
    Int Rev Psychiatry 24:278-85. 2012
  4. ncbi request reprint Bedrich Smetana - art and disease
    Cyril Hoschl
    Prague Psychiatric Centre, Prague, Czech Republic
    Psychiatr Danub 24:S176-8. 2012
  5. doi request reprint European Psychiatric Association guidance on the conflicts of interest
    C Hoschl
    Prague Psychiatric Center, Czech Republic
    Eur Psychiatry 27:142-6. 2012
  6. ncbi request reprint Hippocampal damage mediated by corticosteroids--a neuropsychiatric research challenge
    C Hoschl
    Prague Psychiatric Centre, Czech Republic
    Eur Arch Psychiatry Clin Neurosci 251:II81-8. 2001
  7. ncbi request reprint Effect of low-frequency rTMS on electromagnetic tomography (LORETA) and regional brain metabolism (PET) in schizophrenia patients with auditory hallucinations
    Jiri Horacek
    Prague Psychiatric Center, Prague, Czech Republic
    Neuropsychobiology 55:132-42. 2007
  8. doi request reprint The change of QEEG prefrontal cordance as a response predictor to antidepressive intervention in bipolar depression. A pilot study
    Martin Bares
    Prague Psychiatric Center, Ustavni 91, Prague 8, Bohnice 181 03, Czech Republic
    J Psychiatr Res 46:219-25. 2012
  9. doi request reprint Low frequency (1-Hz), right prefrontal repetitive transcranial magnetic stimulation (rTMS) compared with venlafaxine ER in the treatment of resistant depression: a double-blind, single-centre, randomized study
    Martin Bares
    Prague Psychiatric Centre, Ustavni 91, Prague 8 Bohnice, 181 03, Czech Republic
    J Affect Disord 118:94-100. 2009
  10. doi request reprint Effectiveness of the information technology-aided program of relapse prevention in schizophrenia (ITAREPS): a randomized, controlled, double-blind study
    Filip Spaniel
    Prague Psychiatric Center, 3rd Faculty of Medicine, Charles University, Center of Neuro psychiatric Studies, Prague, Czech Republic
    J Psychiatr Pract 18:269-80. 2012

Collaborators

Detail Information

Publications49

  1. doi request reprint European psychiatry: needs, challenges and structures
    Cyril Hoschl
    Prague Psychiatric Centre, 3rd Faculty of Medicine, Charles University, Ustavni 91, 181 03 Praha 8, Czech Republic
    Eur Arch Psychiatry Clin Neurosci 259:S119-22. 2009
    ..The needs of harmonisation of research, educational, legislative, and political activities in the field of mental health on the European level are briefly discussed...
  2. pmc The media and intellectuals' response to medical publications: the antidepressants' case
    Konstantinos N Fountoulakis
    3rd Department of Psychiatry, School of Medicine, Aristotle University of Thessaloniki, 54636, Thessaloniki, Greece
    Ann Gen Psychiatry 12:11. 2013
    ..It seems that this line of thought represents another aspect of the stigma attached to people suffering from mental illness...
  3. doi request reprint The state of psychiatry in the Czech Republic
    Cyril Hoschl
    Prague Psychiatric Centre, Prague, Czech Republic
    Int Rev Psychiatry 24:278-85. 2012
    ....
  4. ncbi request reprint Bedrich Smetana - art and disease
    Cyril Hoschl
    Prague Psychiatric Centre, Prague, Czech Republic
    Psychiatr Danub 24:S176-8. 2012
    ..In this article we discuss what we can discover about Bedrich Smetana's illness and its effect on his art...
  5. doi request reprint European Psychiatric Association guidance on the conflicts of interest
    C Hoschl
    Prague Psychiatric Center, Czech Republic
    Eur Psychiatry 27:142-6. 2012
    ....
  6. ncbi request reprint Hippocampal damage mediated by corticosteroids--a neuropsychiatric research challenge
    C Hoschl
    Prague Psychiatric Centre, Czech Republic
    Eur Arch Psychiatry Clin Neurosci 251:II81-8. 2001
    ....
  7. ncbi request reprint Effect of low-frequency rTMS on electromagnetic tomography (LORETA) and regional brain metabolism (PET) in schizophrenia patients with auditory hallucinations
    Jiri Horacek
    Prague Psychiatric Center, Prague, Czech Republic
    Neuropsychobiology 55:132-42. 2007
    ..A neuroimaging study elucidating the effect of rTMS in auditory hallucinations has yet to be published...
  8. doi request reprint The change of QEEG prefrontal cordance as a response predictor to antidepressive intervention in bipolar depression. A pilot study
    Martin Bares
    Prague Psychiatric Center, Ustavni 91, Prague 8, Bohnice 181 03, Czech Republic
    J Psychiatr Res 46:219-25. 2012
    ..The aim of the study was to examine whether the change of quantitative EEG (QEEG) theta prefrontal cordance after one week of various antidepressive interventions predicts response to a 4-week treatment in patients with bipolar depression...
  9. doi request reprint Low frequency (1-Hz), right prefrontal repetitive transcranial magnetic stimulation (rTMS) compared with venlafaxine ER in the treatment of resistant depression: a double-blind, single-centre, randomized study
    Martin Bares
    Prague Psychiatric Centre, Ustavni 91, Prague 8 Bohnice, 181 03, Czech Republic
    J Affect Disord 118:94-100. 2009
    ..This double-blind study compared efficacy of l Hz rTMS over the right prefrontal dorsolateral cortex with venlafaxine ER in the treatment of resistant depression...
  10. doi request reprint Effectiveness of the information technology-aided program of relapse prevention in schizophrenia (ITAREPS): a randomized, controlled, double-blind study
    Filip Spaniel
    Prague Psychiatric Center, 3rd Faculty of Medicine, Charles University, Center of Neuro psychiatric Studies, Prague, Czech Republic
    J Psychiatr Pract 18:269-80. 2012
    ..To evaluate the effectiveness of the Information Technology-Aided Program of Re lapse Prevention in Schizophrenia (ITAREPS)...
  11. doi request reprint The change of prefrontal QEEG theta cordance as a predictor of response to bupropion treatment in patients who had failed to respond to previous antidepressant treatments
    Martin Bares
    Prague Psychiatric Center, Ustavni 91, Prague 8 Bohnice, 181 03, Czech Republic
    Eur Neuropsychopharmacol 20:459-66. 2010
    ..9 and 0.75, respectively. Conclusion: Similar to other antidepressants, the reduction of prefrontal QEEG cordance might be helpful in the prediction of the acute outcome of bupropion treatment...
  12. doi request reprint Early reduction in prefrontal theta QEEG cordance value predicts response to venlafaxine treatment in patients with resistant depressive disorder
    Martin Bares
    Prague Psychiatric Centre, Ustavni 91, 181 03 Prague 8, Bohnice, Czech Republic
    Eur Psychiatry 23:350-5. 2008
    ..We have now examined whether decrease of prefrontal quantitative EEG (QEEG) cordance value after 1 week of venlafaxine treatment predicts clinical response to venlafaxine in resistant patients...
  13. doi request reprint Latent toxoplasmosis reduces gray matter density in schizophrenia but not in controls: voxel-based-morphometry (VBM) study
    Jiri Horacek
    Prague Psychiatric Centre, Faculty of Science of Charles University, Prague, Czech Republic
    World J Biol Psychiatry 13:501-9. 2012
    ..To address the role of latent T. gondii infection in schizophrenia we studied the influence of latent toxoplasmosis on brain morphology...
  14. doi request reprint Behavioral, neurochemical and pharmaco-EEG profiles of the psychedelic drug 4-bromo-2,5-dimethoxyphenethylamine (2C-B) in rats
    Tomas Palenicek
    Prague Psychiatric Center, Ustavni 91, 181 03 Bohnice, Prague 8, Czech Republic
    Psychopharmacology (Berl) 225:75-93. 2013
    ..Behavioral, neurochemical and pharmaco-EEG profiles of a new synthetic drug 4-bromo-2,5-dimethoxyphenethylamine (2C-B) in rats were examined...
  15. doi request reprint Genetic variation in FOXP2 alters grey matter concentrations in schizophrenia patients
    Filip Spaniel
    Prague Psychiatric Centre, Prague, Czech Republic
    Neurosci Lett 493:131-5. 2011
    ..Our data suggest that GMC reductions in schizophrenia may be driven by C allele carriers of the FOXP2 gene variant...
  16. doi request reprint Electroencephalographic spectral and coherence analysis of ketamine in rats: correlation with behavioral effects and pharmacokinetics
    Tomas Palenicek
    Prague Psychiatric Center, Prague, Czech Republic
    Neuropsychobiology 63:202-18. 2011
    ..Analyses of behavioral measurements--locomotion and sensorimotor gating--and the pharmacokinetics of ketamine and norketamine were also conducted...
  17. ncbi request reprint ITAREPS: information technology aided relapse prevention programme in schizophrenia
    Filip Spaniel
    Prague Psychiatric Center, Ustavní 191 181 03 Prague 8, Czech Republic
    Schizophr Res 98:312-7. 2008
    ..e. adherence to the programme and involvement of a family member) suggest a critical role of the programme in controlling the number of relapses and subsequent hospitalizations in psychosis...
  18. ncbi request reprint Regional brain metabolism as the predictor of performance on the Trail Making Test in schizophrenia. A 18FDG PET covariation study
    Jiri Horacek
    Centre of Neuropsychiatric Studies, Prague Psychiatric Center, Prague, Czech Republic
    Neuro Endocrinol Lett 27:587-94. 2006
    ..Resting brain metabolism was investigated by (18)FDG positron emission tomography (PET) as the probe for the relative regional synaptic strength and density...
  19. doi request reprint Antidepressant monotherapy compared with combinations of antidepressants in the treatment of resistant depressive patients: a randomized, open-label study
    Martin Bares
    Prague Psychiatric Center, Prague, Czech Republic
    Int J Psychiatry Clin Pract 17:35-43. 2013
    ..This randomized, 6-week, open-label study compared efficacy of CAD and antidepressant monotherapies (ADM) that had been chosen according to clinical judgment of the attending psychiatrist...
  20. doi request reprint Individualized rTMS neuronavigated according to regional brain metabolism ((18)FGD PET) has better treatment effects on auditory hallucinations than standard positioning of rTMS: a double-blind, sham-controlled study
    Monika Klirova
    Prague Psychiatric Center, Ustavni 91, Prague 8, 181 03, Czech Republic
    Eur Arch Psychiatry Clin Neurosci 263:475-84. 2013
    ..Our data showed acute efficacy of (18)FDG PET-guided rTMS in the treatment of AHs. Neuronavigated rTMS was found to be more effective than standard, anatomically guided rTMS. ..
  21. ncbi request reprint Trazodone improves the results of cognitive behaviour therapy of primary insomnia in non-depressed patients
    Lucie Zavesicka
    Prague Psychiatric Center, 3rd Faculty of Medicine, Charles University, Ustavni 91, 181 03 Praha 8 Bohnice, Czech Republic
    Neuro Endocrinol Lett 29:895-901. 2008
    ..The present study was undertaken to evaluate the clinical efficacy of CBT, singly and combined with trazodone pharmacotherapy, for primary insomnia...
  22. doi request reprint EEG source analysis in obsessive-compulsive disorder
    Jana Koprivova
    Prague Psychiatric Centre, Prague, Czech Republic
    Clin Neurophysiol 122:1735-43. 2011
    ..The goal of this study was to assess the activity of intracortical EEG sources in patients with OCD...
  23. doi request reprint Expression of the hippocampal NMDA receptor GluN1 subunit and its splicing isoforms in schizophrenia: postmortem study
    Monika Vrajová
    Prague Psychiatric Center, Ustavni 91, 181 03, Prague 8, Czech Republic
    Neurochem Res 35:994-1002. 2010
    ....
  24. ncbi request reprint Are there any differences in the efficacy among second generation antipsychotics in the treatment of schizophrenia and related disorders?
    Lucie Motlova
    Prague Psychiatric Centre, Centre of Neuropsychiatric Studies and Charles University, 3rd Medical Faculty, Prague, Czech Republic
    Ann Clin Psychiatry 19:133-43. 2007
    ..The goal of this review is to summarize the results of head to head efficacy studies that compare second generation antipsychotics in the treatment of schizophrenia and related disorders...
  25. doi request reprint Brain structural signature of familial predisposition for bipolar disorder: replicable evidence for involvement of the right inferior frontal gyrus
    Tomas Hajek
    Department of Psychiatry, Dalhousie University, Halifax, Canada
    Biol Psychiatry 73:144-52. 2013
    ..Thus, we examined the associations among genetic risk, illness burden, lithium treatment, and brain structure in BD...
  26. ncbi request reprint The effects of siRNA-mediated RGS4 gene silencing on the whole genome transcription profile: implications for schizophrenia
    Monika Vrajová
    Prague Psychiatric Centre, Czech Republic
    Neuro Endocrinol Lett 32:246-52. 2011
    ..The mechanism of RGS4 involvement in the pathophysiology of this illness is not clear...
  27. ncbi request reprint The effect of tryptophan depletion on the action of haloperidol in MK-801-treated rats
    Vera Bubenikova
    Prague Psychiatric Center and Center of Neuropsychiatric Studies, 181 03 Prague 8, Czech Republic
    Eur J Pharmacol 502:109-16. 2004
    ..The effect of the tryptophan-free mixture combined with the classical antipsychotic haloperidol in MK-801-treated rats indicates the possibly important role of the serotonergic system in the action of antipsychotics...
  28. ncbi request reprint Higher prevalence of antibodies to Borrelia burgdorferi in psychiatric patients than in healthy subjects
    Tomas Hajek
    Prague Psychiatric Center, Department of Epidemiology, Charles University, Third Faculty of Medicine, Czech Republic
    Am J Psychiatry 159:297-301. 2002
    ..The authors compared the prevalence of antibodies to Borrelia burgdorferi in groups of psychiatric patients and healthy subjects to find out whether there is an association between this infection and psychiatric morbidity...
  29. ncbi request reprint The change of regional brain metabolism (18FDG PET) in panic disorder during the treatment with cognitive behavioral therapy or antidepressants
    Jan Prasko
    Prague Psychiatric Centre, 3rd Faculty of Medicine Charles University Prague, Centre of Neuropsychiatric Studies, Prague, Czech Republic
    Neuro Endocrinol Lett 25:340-8. 2004
    ..The goal of our study was to identify brain structures in patients with panic disorder (PD) that show changes in 18FDG PET during the treatment with cognitive behavioral therapy (CBT) or antidepressants...
  30. ncbi request reprint Magnetic resonance relaxometry in monozygotic twins discordant and concordant for schizophrenia
    Filip Spaniel
    Psychiatric Center Prague, Ustavni 91, 181 03 Prague 8, Bohnice, Czech Republic
    Eur Psychiatry 20:41-4. 2005
    ..Patients with schizophrenia (n = 11) showed significant prolongation in T1 relaxation times in the globus pallidus (GP) bilaterally (P < 0.005, Bonferroni corrected) when compared to 14 healthy MZ twins...
  31. ncbi request reprint Mechanism of action of atypical antipsychotic drugs and the neurobiology of schizophrenia
    Jiri Horacek
    Prague Psychiatric Centre, Prague, Czech Republic
    CNS Drugs 20:389-409. 2006
    ..This mechanism may normalise glutamatergic dysfunction and structural abnormalities and affect the core pathophysiological substrates for schizophrenia...
  32. ncbi request reprint Language lateralization in monozygotic twins discordant and concordant for schizophrenia. A functional MRI pilot study
    Filip Spaniel
    Psychiatric Center, Ustavní 191, 181 03 Prague 8, Czech Republic
    Eur Psychiatry 22:319-22. 2007
    ..Previous studies have suggested altered structural and functional asymmetry of the brain in schizophrenia...
  33. doi request reprint Medial frontal and dorsal cortical morphometric abnormalities are related to obsessive-compulsive disorder
    Jana Koprivova
    Prague Psychiatric Centre, Prague, Czech Republic
    Neurosci Lett 464:62-6. 2009
    ..The relationships between OCD and clinical variables provide further evidence that frontal, parietal and occipital structures play a role in the disorder...
  34. ncbi request reprint Alterations in calcium homeostasis as biological marker for mild Alzheimer's disease?
    D Ripova
    Prague Psychiatric Center, Ustavni 91, 181 03 Prague 8, Czech Republic
    Physiol Res 53:449-52. 2004
    ..Measurement of calcium homeostasis could provide a very sensitive, but less specific biological marker of AD. These results support the hypothesis that influencing calcium homeostasis may provide a therapeutic strategy in dementia...
  35. ncbi request reprint The effect of tryptophan depletion on brain activation measured by functional magnetic resonance imaging during the Stroop test in healthy subjects
    J Horacek
    Prague Psychiatric Centre, Ustavni 91, 18100 Prague 8, Czech Republic
    Physiol Res 54:235-44. 2005
    ..The present findings allow the postulate that serotonergic medial forebrain and cingulum bundle pathways play a role in the activity of cortical structures involved in Stroop test processing...
  36. ncbi request reprint Phosphoinositide signalling system in platelets of schizophrenic patients and the effect of neuroleptic therapy
    D Ripova
    Laboratory of Biochemistry, Prague Psychiatric Center, Czech Republic
    Prostaglandins Leukot Essent Fatty Acids 61:125-9. 1999
    ..Neuroleptic therapy did not remove the observed changes in [Ca2+]i and IP3 levels...
  37. ncbi request reprint Clinical and demographic characteristics of psychiatric patients seropositive for Borrelia burgdorferi
    T Hajek
    Prague Psychiatric Center, Charles University, 3rd School of Medicine, Prague, Czech Republic
    Eur Psychiatry 21:118-22. 2006
    ..We compared clinical and demographic variables in Bb seropositive and seronegative psychiatric patients and healthy controls...
  38. ncbi request reprint Cytosolic calcium alterations in platelets of patients with early stages of Alzheimer's disease
    D Rípovi
    Laboratory of Biochemistry, Prague Psychiatric Center, Prague, Czech Republic
    Neurobiol Aging 21:729-34. 2000
    ..We suggest that the disturbed calcium homeostasis in AD is an "early defect."..
  39. ncbi request reprint The relationship between central serotonergic activity and insulin sensitivity in healthy volunteers
    J Horacek
    3rd Faculty of Medicine, Charles University, Prague, Czech Republic
    Psychoneuroendocrinology 24:785-97. 1999
    ..The data support the hypothesis of a close connection between 5-HT activity in the brain and peripheral sensitivity to insulin. The possible physiological mechanisms of this connection are discussed...
  40. pmc The Information Technology Aided Relapse Prevention Programme in Schizophrenia: an extension of a mirror-design follow-up
    F Spaniel
    Prague Psychiatric Center, Prague, Czech Republic
    Int J Clin Pract 62:1943-6. 2008
    ....
  41. doi request reprint Behavioral, hyperthermic and pharmacokinetic profile of para-methoxymethamphetamine (PMMA) in rats
    Tomas Palenicek
    Prague Psychiatric Center, Ustavni 91, 181 03 Prague 8, Bohnice, Czech Republic
    Pharmacol Biochem Behav 98:130-9. 2011
    ..High doses of PMMA have a gradual penetration to the brain which might lead to the delayed peak concentrations and prolonged effects of the drug...
  42. pmc Smaller hippocampal volumes in patients with bipolar disorder are masked by exposure to lithium: a meta-analysis
    Tomas Hajek
    Department of Psychiatry, Dalhousie University, Halifax, NS, Canada
    J Psychiatry Neurosci 37:333-43. 2012
    ..Preserved hippocampal volumes in most studies of participants with bipolar disorder may reflect potential neuroprotective effects of lithium (Li)...
  43. ncbi request reprint Changes in QEEG prefrontal cordance as a predictor of response to antidepressants in patients with treatment resistant depressive disorder: a pilot study
    Martin Bares
    Prague Psychiatric Centre, Ustavni 91, Prague 8 Bohnice, 181 03, Czech Republic 3rd Faculty of Medicine, Charles University, Ruska 87, Prague 10, 100 00, Czech Republic
    J Psychiatr Res 41:319-25. 2007
    ..We examined whether early QEEG decrease represents a phenomenon associated with response to treatment with different antidepressants in patients with treatment resistant depression...
  44. doi request reprint Models of schizophrenia in humans and animals based on inhibition of NMDA receptors
    Vera Bubenikova-Valesova
    Prague Psychiatric Center, Prague, Czech Republic
    Neurosci Biobehav Rev 32:1014-23. 2008
    ....
  45. ncbi request reprint Prospective study of hippocampal volume and function in human subjects treated with corticosteroids
    Tomas Hajek
    Prague Psychiatric Center and Charles University, 3rd School of Medicine, Prague, Czech Republic
    Eur Psychiatry 21:123-8. 2006
    ..This is the first prospective study of hippocampal volume and function in patients treated with corticosteroids...
  46. doi request reprint Escitalopram for the treatment of major depression and anxiety disorders
    Cyril Hoschl
    Prague Psychiatric Centre, Ustavni 91, 181 03 Praha 8, Czech Republic
    Expert Rev Neurother 8:537-52. 2008
    ..Escitalopram is an effective first-line option in the management of patients with major depression, including severe forms, and various anxiety disorders...
  47. doi request reprint Teaching critical appraisal of articles on psychopharmacology
    Pavel Mohr
    Clinical Division, Prague Psychiatric Center, Praha, Czech Republic
    Acad Psychiatry 36:114-7. 2012
    ..Psychiatrists and other physicians sometimes read publications superficially, relying excessively on abstracts. The authors addressed this problem by teaching critical appraisal of individual articles...
  48. ncbi request reprint Moclobemide and cognitive behavioral therapy in the treatment of social phobia. A six-month controlled study and 24 months follow up
    Jan Prasko
    Psychiatric Centre Prague, Ustavni 91, 181 03 Prague 8, Czech Republic
    Neuro Endocrinol Lett 27:473-81. 2006
    ..The relapse rate during the 24-month follow up was significantly lower in the group treated with CBT in comparison with the group A. formerly treated with moclobemide alone...
  49. ncbi request reprint The double-blind sham-controlled study of high-frequency rTMS (20 Hz) for negative symptoms in schizophrenia: negative results
    Tomas Novak
    Psychiatric Centre Prague, Charles University, 3rd School of Medicine in Prague, Czech Republic
    Neuro Endocrinol Lett 27:209-13. 2006
    ..Results from our study did not confirm that HF-rTMS over the left DLPCF affects the negative symptoms of schizophrenia and alternative rTMS approaches are discussed...