P Drevinek

Summary

Affiliation: Charles University
Country: Czech Republic

Publications

  1. ncbi request reprint High genotypic diversity of Pseudomonas aeruginosa strains isolated from patients with cystic fibrosis in the Czech Republic
    Sarka Vosahlikova
    Department of Paediatrics, 2nd Medical School, Charles University in Prague, Uvalu 84, 15006 Prague 5, Czech Republic
    Res Microbiol 158:324-9. 2007
  2. pmc Reference percentiles for FEV(1) and BMI in European children and adults with cystic fibrosis
    Pierre Yves Boelle
    AP HP, Hôpital Trousseau Pediatric Pulmonary Department, Hopital St Antoine Public Health Department, Paris, France
    Orphanet J Rare Dis 7:64. 2012
  3. pmc Use of colony-based bacterial strain typing for tracking the fate of Lactobacillus strains during human consumption
    Eshwar Mahenthiralingam
    Cardiff School of Biosciences, Cardiff University, Cardiff, Wales CF103TL, UK
    BMC Microbiol 9:251. 2009
  4. pmc Direct PCR detection of Burkholderia cepacia complex and identification of its genomovars by using sputum as source of DNA
    Pavel Drevinek
    2nd Department of Pediatrics, 2nd Medical School of Charles University, Prague, Czech Republic
    J Clin Microbiol 40:3485-8. 2002
  5. pmc Gene expression changes linked to antimicrobial resistance, oxidative stress, iron depletion and retained motility are observed when Burkholderia cenocepacia grows in cystic fibrosis sputum
    Pavel Drevinek
    Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    BMC Infect Dis 8:121. 2008
  6. pmc Oxidative stress of Burkholderia cenocepacia induces insertion sequence-mediated genomic rearrangements that interfere with macrorestriction-based genotyping
    Pavel Drevinek
    Cardiff School of Biosciences, Cardiff University, Cardiff, United Kingdom
    J Clin Microbiol 48:34-40. 2010
  7. pmc Direct culture-independent Strain typing of Burkholderia cepacia complex in sputum samples from patients with cystic fibrosis
    Pavel Drevinek
    Department of Pediatrics, 2nd Medical School, Charles University, V Uvalu 84, 150 06 Prague, Czech Republic
    J Clin Microbiol 48:1888-91. 2010
  8. doi request reprint Burkholderia cenocepacia in cystic fibrosis: epidemiology and molecular mechanisms of virulence
    P Drevinek
    Paediatric Department, 2nd Medical School, Charles University, Prague, Czech Republic
    Clin Microbiol Infect 16:821-30. 2010
  9. ncbi request reprint HLA-DQ polymorphisms modify the risk of thyroid autoimmunity in children with type 1 diabetes mellitus
    Z Sumnik
    2nd Department of Pediatrics, 2nd Medical School, Charles University, Prague, Czech Republic
    J Pediatr Endocrinol Metab 16:851-8. 2003
  10. ncbi request reprint Widespread clone of Burkholderia cenocepacia in cystic fibrosis patients in the Czech Republic
    Pavel Drevinek
    Paediatric Department, Charles University 2nd Medical School, Prague, Czech Republic
    J Med Microbiol 54:655-9. 2005

Collaborators

Detail Information

Publications23

  1. ncbi request reprint High genotypic diversity of Pseudomonas aeruginosa strains isolated from patients with cystic fibrosis in the Czech Republic
    Sarka Vosahlikova
    Department of Paediatrics, 2nd Medical School, Charles University in Prague, Uvalu 84, 15006 Prague 5, Czech Republic
    Res Microbiol 158:324-9. 2007
    ..The absence of highly epidemic P. aeruginosa strains may result from infection control measures taken upon recognition of the epidemic B. cenocepacia...
  2. pmc Reference percentiles for FEV(1) and BMI in European children and adults with cystic fibrosis
    Pierre Yves Boelle
    AP HP, Hôpital Trousseau Pediatric Pulmonary Department, Hopital St Antoine Public Health Department, Paris, France
    Orphanet J Rare Dis 7:64. 2012
    ..Here, we used a large database of European CF patients to compute CF specific reference equations for FEV(1) and BMI, derived CF-specific percentile charts and compared these European data to their nearest international equivalents...
  3. pmc Use of colony-based bacterial strain typing for tracking the fate of Lactobacillus strains during human consumption
    Eshwar Mahenthiralingam
    Cardiff School of Biosciences, Cardiff University, Cardiff, Wales CF103TL, UK
    BMC Microbiol 9:251. 2009
    ..We examined the cultivable diversity of LAB in the human gut before and after feeding with two Lactobacillus strains, and also tracked the fate of these two administered strains using a RAPD technique...
  4. pmc Direct PCR detection of Burkholderia cepacia complex and identification of its genomovars by using sputum as source of DNA
    Pavel Drevinek
    2nd Department of Pediatrics, 2nd Medical School of Charles University, Prague, Czech Republic
    J Clin Microbiol 40:3485-8. 2002
    ..The product of the first PCR round is also used to identify the genomovar of the pathogen. The protocol achieves high sensitivity and specificity with simple interpretation of genomovar status...
  5. pmc Gene expression changes linked to antimicrobial resistance, oxidative stress, iron depletion and retained motility are observed when Burkholderia cenocepacia grows in cystic fibrosis sputum
    Pavel Drevinek
    Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    BMC Infect Dis 8:121. 2008
    ..Their large genome (> 7000 genes) and multiple pathways encoding the same putative functions make virulence factor identification difficult in these bacteria...
  6. pmc Oxidative stress of Burkholderia cenocepacia induces insertion sequence-mediated genomic rearrangements that interfere with macrorestriction-based genotyping
    Pavel Drevinek
    Cardiff School of Biosciences, Cardiff University, Cardiff, United Kingdom
    J Clin Microbiol 48:34-40. 2010
    ..cenocepacia. These IS movements may alter the PFGE fingerprints of isolates that are clonal by other typing methods...
  7. pmc Direct culture-independent Strain typing of Burkholderia cepacia complex in sputum samples from patients with cystic fibrosis
    Pavel Drevinek
    Department of Pediatrics, 2nd Medical School, Charles University, V Uvalu 84, 150 06 Prague, Czech Republic
    J Clin Microbiol 48:1888-91. 2010
    ..The redesigned nested-PCR MLST format was successfully used to accurately identify strains in 23 sputum samples, of which 8 were culture negative...
  8. doi request reprint Burkholderia cenocepacia in cystic fibrosis: epidemiology and molecular mechanisms of virulence
    P Drevinek
    Paediatric Department, 2nd Medical School, Charles University, Prague, Czech Republic
    Clin Microbiol Infect 16:821-30. 2010
    ....
  9. ncbi request reprint HLA-DQ polymorphisms modify the risk of thyroid autoimmunity in children with type 1 diabetes mellitus
    Z Sumnik
    2nd Department of Pediatrics, 2nd Medical School, Charles University, Prague, Czech Republic
    J Pediatr Endocrinol Metab 16:851-8. 2003
    ..PATIENTS AND METLHODS: Screening for TAI was performed in 285 children with DM1 by measuring autoantibodies against thyroid peroxidase (anti-TPO) and thyroglobulin (anti-Tg). HLA-DQA1 and -DQB1 were genotyped using PCR-SSP...
  10. ncbi request reprint Widespread clone of Burkholderia cenocepacia in cystic fibrosis patients in the Czech Republic
    Pavel Drevinek
    Paediatric Department, Charles University 2nd Medical School, Prague, Czech Republic
    J Med Microbiol 54:655-9. 2005
    ..cepacia epidemic strain marker, PCR negativity for the cable pilin subunit gene and close genetic relatedness to the epidemic strain of RAPD 01 type previously identified in Canada...
  11. ncbi request reprint Higher maternal age at delivery, and lower birth orders are associated with increased risk of childhood type 1 diabetes mellitus
    Z Sumnik
    Department of Paediatrics, 2nd Medical School, Charles University, V Uvalu 84, Prague 5, The Czech Republic
    Exp Clin Endocrinol Diabetes 112:294-7. 2004
    ..We detected no independent effect of maternal education, either. Our study provides further evidence that the risk of Type 1 diabetes in the offspring increases with higher maternal age at delivery and lower birth order...
  12. pmc Multilocus sequence typing breathes life into a microbial metagenome
    Eshwar Mahenthiralingam
    Cardiff School of Biosciences, Cardiff University, United Kingdom
    PLoS ONE 1:e17. 2006
    ....
  13. ncbi request reprint Longitudinal observation of enterovirus and adenovirus in stool samples from Norwegian infants with the highest genetic risk of type 1 diabetes
    O Cinek
    Motol University Hospital, Charles University Prague, V Uvalu 85, CZ 150 06 Praha 5, The Czech Republic
    J Clin Virol 35:33-40. 2006
    ..Data on occurrence and course of the infections in infancy are therefore important for designing effective approaches towards study of the association...
  14. ncbi request reprint [Type I diabetes mellitus and associated autoimmune diseases in the first-degree relatives of diabetic children: questionnaire based study]
    H Malcova
    Pediatrická klinika 2 LF UK a FNM, Praha
    Cas Lek Cesk 143:625-9. 2004
    ..The shared genetic background may play a role in the disease pathogenesis. The aim of our study was to assess the prevalence of T1DM and other autoimmune disorders in the first-degree relatives of diabetic children...
  15. ncbi request reprint [Association of insulin gene variants with type 1 diabetes mellitus in Czech population]
    O Cinek
    Pediatrická klinika 2 LF UK a FNM, Praha
    Cas Lek Cesk 143:318-22. 2004
    ..The objective of the study was to quantify the association of insulin gene variants with type 1 diabetes mellitus (TIDM) in the Czech population...
  16. pmc Diversity of the parB and repA genes of the Burkholderia cepacia complex and their utility for rapid identification of Burkholderia cenocepacia
    Pavel Drevinek
    Cardiff School of Biosciences, Cardiff University, Cardiff, CF10 3TL, UK
    BMC Microbiol 8:44. 2008
    ....
  17. doi request reprint DNA profiling of Stenotrophomonas maltophilia by PCR targeted to its species-specific repetitive palindromic sequences
    J Nunvar
    Department of Genetics and Microbiology, Faculty of Science, Charles University, Prague, Czech Republic
    Lett Appl Microbiol 54:59-66. 2012
    ....
  18. ncbi request reprint The CTLA4 +49 A/G dimorphism is not associated with type 1 diabetes in Czech children
    O Cinek
    2nd Department of Paediatrics, 2nd Medical School, Charles University, Prague, Czech Republic
    Eur J Immunogenet 29:219-22. 2002
    ..This may be another piece of evidence against the +49 A/G transition as the aetiological polymorphism within the CTLA4 gene...
  19. ncbi request reprint Absence of breast-feeding is associated with the risk of type 1 diabetes: a case-control study in a population with rapidly increasing incidence
    Hana Malcova
    Department of Paediatrics, Motol University Hospital, Charles University, V Uvalu 84, 150 06 rague 5, Czech Republic
    Eur J Pediatr 165:114-9. 2006
    ..Short breast-feeding period and short attendance to day care is associated with the risk of T1DM in Czech children...
  20. pmc Elucidating global epidemiology of Burkholderia multivorans in cases of cystic fibrosis by multilocus sequence typing
    Adam Baldwin
    Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom
    J Clin Microbiol 46:290-5. 2008
    ..multivorans...
  21. pmc Environmental Burkholderia cepacia complex isolates in human infections
    Adam Baldwin
    Warwick University, Coventry, Wales, United Kingdom
    Emerg Infect Dis 13:458-61. 2007
    ..This finding links the natural environment with the emergence of many Bcc infections...
  22. ncbi request reprint Genomovar distribution of the Burkholderia cepacia complex differs significantly between Czech and Slovak patients with cystic fibrosis
    Pavel Drevinek
    J Med Microbiol 52:603-4. 2003
  23. ncbi request reprint Identification of putative noncoding RNA genes in the Burkholderia cenocepacia J2315 genome
    Tom Coenye
    Laboratorium voor Microbiologie, Universiteit Gent, Gent, Belgium
    FEMS Microbiol Lett 276:83-92. 2007
    ..The presence of a large number of ncRNA genes in this organism may help to explain its complexity, phenotypic variability and ability to survive in a remarkably wide range of environments...