David Cibula

Summary

Affiliation: Charles University
Country: Czech Republic

Publications

  1. doi request reprint Bilateral ultrastaging of sentinel lymph node in cervical cancer: Lowering the false-negative rate and improving the detection of micrometastasis
    David Cibula
    Gynecological Oncology Centre, Department of Obstetrics and Gynecology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Czech Republic
    Gynecol Oncol 127:462-6. 2012
  2. doi request reprint Prognostic significance of low volume sentinel lymph node disease in early-stage cervical cancer
    D Cibula
    Gynecological Oncology Centre, Department of Obstetrics and Gynecology, First Faculty of Medicine and General University Hospital, Charles University, Prague, Czech Republic
    Gynecol Oncol 124:496-501. 2012
  3. ncbi request reprint The role of androgens in determining acne severity in adult women
    D Cibula
    Department of Obstetrics and Gynecology, General Teaching Hospital in Prague, Charles University, Apolinarska 18, 120 00 Prague 2, Czech Republic
    Br J Dermatol 143:399-404. 2000
  4. doi request reprint Underlying mechanisms of ovarian cancer risk reduction after tubal ligation
    David Cibula
    Oncogynecological Center, Department of Obstetrics and Gynecology, General Teaching Hospital, First Medical School, Charles University, Prague, Czech Republic
    Acta Obstet Gynecol Scand 90:559-63. 2011
  5. ncbi request reprint [Informed consent for factor V Leiden mutation screening before recommending use of combined hormonal contraceptives or hormone replacement therapy ]
    D Cibula
    Gynekologicko porodnická klinika 1 LF UK a VFN v Praze Apolinárská 18 128 00 Praha 2
    Ceska Gynekol 68:212. 2003
  6. doi request reprint Abdominal radical trachelectomy in fertility-sparing treatment of early-stage cervical cancer
    David Cibula
    Oncogynecological Center, Department of Obstetrics and Gynecology, General Teaching Hospital, First Medical School, Charles University, Prague, Czech Republic
    Int J Gynecol Cancer 19:1407-11. 2009
  7. doi request reprint Oral contraceptives and risk of ovarian and breast cancers in BRCA mutation carriers: a meta-analysis
    David Cibula
    Gynecological Oncologic Centre, First Faculty of Medicine and General University Hospital, Charles University, Apolinarska 18, Prague 2, Czech Republic
    Expert Rev Anticancer Ther 11:1197-207. 2011
  8. ncbi request reprint Is insulin resistance an essential component of PCOS?: The influence of confounding factors
    D Cibula
    Department of Obstetrics and Gynecology, Charles University, Apolinarska 18, Prague 2, 120 00, Czech Republic
    Hum Reprod 19:757-9. 2004
  9. doi request reprint Tubal ligation and the risk of ovarian cancer: review and meta-analysis
    D Cibula
    Oncogynecological Centre, Department of Obstetrics and Gynecology, General Teaching Hospital, First Medical School, Charles University, Prague, Czech Republic
    Hum Reprod Update 17:55-67. 2011
  10. ncbi request reprint Laparoscopic abdominal radical trachelectomy
    D Cibula
    Department of Obstetrics and Gynecology, General Faculty Hospital and 1st Medical Faculty of Charles University, Apolinarska 18, Prague 2, Czech Republic
    Gynecol Oncol 97:707-9. 2005

Detail Information

Publications70

  1. doi request reprint Bilateral ultrastaging of sentinel lymph node in cervical cancer: Lowering the false-negative rate and improving the detection of micrometastasis
    David Cibula
    Gynecological Oncology Centre, Department of Obstetrics and Gynecology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Czech Republic
    Gynecol Oncol 127:462-6. 2012
    ..To evaluate the sensitivity of sentinel node (SN) ultrastaging and to define parameters that may reduce the overall false-negative rate in women with early-stage cervical cancer...
  2. doi request reprint Prognostic significance of low volume sentinel lymph node disease in early-stage cervical cancer
    D Cibula
    Gynecological Oncology Centre, Department of Obstetrics and Gynecology, First Faculty of Medicine and General University Hospital, Charles University, Prague, Czech Republic
    Gynecol Oncol 124:496-501. 2012
    ..Although pathologic ultrastaging of SN allows for identification of low volume disease, including micro-metastasis and isolated tumor cells (ITC), in up to 15% of cases, prognostic significance of these findings is unknown...
  3. ncbi request reprint The role of androgens in determining acne severity in adult women
    D Cibula
    Department of Obstetrics and Gynecology, General Teaching Hospital in Prague, Charles University, Apolinarska 18, 120 00 Prague 2, Czech Republic
    Br J Dermatol 143:399-404. 2000
    ..Although many arguments have been put forth supporting the role of androgens in the aetiology of acne, their part in determining the severity of the disease is not well established...
  4. doi request reprint Underlying mechanisms of ovarian cancer risk reduction after tubal ligation
    David Cibula
    Oncogynecological Center, Department of Obstetrics and Gynecology, General Teaching Hospital, First Medical School, Charles University, Prague, Czech Republic
    Acta Obstet Gynecol Scand 90:559-63. 2011
    ..Prevention of retrograde transport of carcinogenic substances from the vagina may be an additional mechanism...
  5. ncbi request reprint [Informed consent for factor V Leiden mutation screening before recommending use of combined hormonal contraceptives or hormone replacement therapy ]
    D Cibula
    Gynekologicko porodnická klinika 1 LF UK a VFN v Praze Apolinárská 18 128 00 Praha 2
    Ceska Gynekol 68:212. 2003
  6. doi request reprint Abdominal radical trachelectomy in fertility-sparing treatment of early-stage cervical cancer
    David Cibula
    Oncogynecological Center, Department of Obstetrics and Gynecology, General Teaching Hospital, First Medical School, Charles University, Prague, Czech Republic
    Int J Gynecol Cancer 19:1407-11. 2009
    ..Abdominal radical trachelectomy (ART) is one of the fertility-sparing procedures in women with early-stage cervical cancer. In comparison with vaginal radical trachelectomy, the published results of ART are so far limited...
  7. doi request reprint Oral contraceptives and risk of ovarian and breast cancers in BRCA mutation carriers: a meta-analysis
    David Cibula
    Gynecological Oncologic Centre, First Faculty of Medicine and General University Hospital, Charles University, Apolinarska 18, Prague 2, Czech Republic
    Expert Rev Anticancer Ther 11:1197-207. 2011
    ..COCs can be considered as an alternative strategy in the chemoprevention of ovarian cancer in BRCA1 mutation carriers who do not accept prophylactic salpingo-oophorectomy above the age of 30 years...
  8. ncbi request reprint Is insulin resistance an essential component of PCOS?: The influence of confounding factors
    D Cibula
    Department of Obstetrics and Gynecology, Charles University, Apolinarska 18, Prague 2, 120 00, Czech Republic
    Hum Reprod 19:757-9. 2004
    ..In conclusion, available data offer evidence that a substantial subgroup of women with PCOS have insulin sensitivity comparable with healthy controls if matched carefully for potential confounding factors...
  9. doi request reprint Tubal ligation and the risk of ovarian cancer: review and meta-analysis
    D Cibula
    Oncogynecological Centre, Department of Obstetrics and Gynecology, General Teaching Hospital, First Medical School, Charles University, Prague, Czech Republic
    Hum Reprod Update 17:55-67. 2011
    ..We have aimed to provide a critical overview of the studies available to date and to conduct a meta-analysis...
  10. ncbi request reprint Laparoscopic abdominal radical trachelectomy
    D Cibula
    Department of Obstetrics and Gynecology, General Faculty Hospital and 1st Medical Faculty of Charles University, Apolinarska 18, Prague 2, Czech Republic
    Gynecol Oncol 97:707-9. 2005
    ..Currently, a technique of abdominal radical approach is used in a few centres. With growing availability of laparoscopy, a novel technique of laparoscopic radical trachelectomy might be an alternative...
  11. doi request reprint Hormonal contraception and risk of cancer
    D Cibula
    Oncogynecological Centre, Department of Obstetrics and Gynecology, General Teaching Hospital in Prague, First Medical School, Charles University, Apolinarska 18, Prague, Czech Republic
    Hum Reprod Update 16:631-50. 2010
    ..Fear from increased cancer risk is one of the most significant reasons for low acceptance of reliable contraceptive methods and low compliance...
  12. doi request reprint Late morbidity following nerve-sparing radical hysterectomy
    D Cibula
    Oncogynecological Center, Department of Obstetrics and Gynecology, General Teaching Hospital in Prague, First Medical School, Charles University, Prague 2, Czech Republic
    Gynecol Oncol 116:506-11. 2010
    ..The aim of the study was to prospectively evaluate the morbidity of patients before and 6 months after NS RH and compare that with the morbidity in patients following different types of parametrectomy without nerve sparing...
  13. doi request reprint Pelvic lymphadenectomy in cervical cancer--surgical anatomy and proposal for a new classification system
    D Cibula
    Oncogynecological Centre, Department of Obstetrics and Gynecology, General Faculty Hospital, First Medical Faculty, Charles University, Apolinarska 18 Prague 2, 12000, Czech Republic
    Gynecol Oncol 116:33-7. 2010
    ..This lack of standardization if corrected will likely facilitate a more clear communication and analysis of outcomes from various institutions, and reduce confusion to trainees about the procedure being performed...
  14. ncbi request reprint The best correlation of the new index of hyperandrogenism with the grade of increased body hair
    D Cibula
    Department of Obstetrics and Gynecology, Apolinarska 18, Prague 2, 120 00, Czech Republic
    Eur J Endocrinol 143:405-8. 2000
    ..The aim of our study was to identify the optimal laboratory marker of androgen production by correlating the markers to the presence or grade of increased body hair as a clinical sign of hyperandrogenism...
  15. ncbi request reprint Women's contraceptive practices and sexual behaviour in Europe
    David Cibula
    Department of Obstetrics and Gynaecology, General Faculty Hospital, Charles University, Prague, Czech Republic
    Eur J Contracept Reprod Health Care 13:362-75. 2008
    ....
  16. ncbi request reprint Insulin sensitivity in non-obese women with polycystic ovary syndrome during treatment with oral contraceptives containing low-androgenic progestin
    D Cibula
    Department of Obstetrics and Gynecology, Charles University, Apolinarska 18, Prague 2, 120 00, Czech Republic
    Hum Reprod 17:76-82. 2002
    ..The study aim was to investigate insulin action and androgen production during treatment with COC containing low-androgenic progestin...
  17. ncbi request reprint Prediction of insulin sensitivity in nonobese women with polycystic ovary syndrome
    D Cibula
    Department of Obstetrics and Gynecology, Charles University, Praha 2, 120 00, Czech Republic
    J Clin Endocrinol Metab 87:5821-5. 2002
    ....
  18. ncbi request reprint [The role apoptosis in the extent of endometriosis and its clinical symptomatology]
    D Cibula
    Gynekologicko porodnická klinika 1 LF UK a VFN v Praze, Praha
    Ceska Gynekol 68:59-63. 2003
    ..To evaluate the presence and intensity of apoptosis in lesions of peritoneal endometriosis. To consider the role of different intensity of apoptosis in the progression of the disease and in the manifestation of clinical symptoms...
  19. ncbi request reprint [Long-term follow-up after complete treatment of peritoneal endometriosis with the CO2 laser]
    D Cibula
    Gynekologicko porodnická klinika 1 LF UK a VFN v Praze, Praha
    Ceska Gynekol 68:63-8. 2003
    ..To evaluate the effect of laparoscopic CO2 laser ablation of peritoneal endometriosis in the treatment of pelvic pain with a long-term follow-up. To differentiate the effect of surgery on different types of pelvic pain...
  20. doi request reprint Factors affecting spontaneous voiding recovery after radical hysterectomy
    David Cibula
    Department of Obstetrics and Gynecology, General Teaching Hospital, First Medical School, Charles University, Prague, Czech Republic
    Int J Gynecol Cancer 20:685-90. 2010
    ..The impairment of spontaneous voiding is the most prominent type of morbidity in the early postoperative period after radical hysterectomy. The aim of our work was to evaluate the parameters affecting the recovery of spontaneous voiding...
  21. doi request reprint Sentinel node (SLN) biopsy in the management of locally advanced cervical cancer
    D Cibula
    Department of Obstetrics and Gynecology, General Teaching Hospital in Prague, First Medical School, Charles University, Oncogynecological Center, Prague 2, Czech Republic
    Gynecol Oncol 115:46-50. 2009
    ..It was the aim of our study to verify the SLN reliability in large tumors, with modified dye application technique and a careful identification of side-specific lymphatic drainage...
  22. ncbi request reprint [Continuous use--the important trend of combined hormonal contraception]
    D Cibula
    Gynekologicko porodnicka klinika, 1 LF UK a VFN, Praha
    Ceska Gynekol 71:66-9. 2006
    ..Review of literature concerning continuous regimen of combined hormonal contraception...
  23. doi request reprint Update on abdominal radical trachelectomy
    David Cibula
    Oncogynecological Center, Department of Obstetrics and Gynecology, General Teaching Hospital, 1st Medical Faculty of the Charles University, Prague, Czech Republic
    Gynecol Oncol 111:S111-5. 2008
    ..In this article, we describe the standard technique of this procedure along with alternatives, including a nerve-sparing modification of the parametrectomy...
  24. ncbi request reprint The effect of combination therapy with metformin and combined oral contraceptives (COC) versus COC alone on insulin sensitivity, hyperandrogenaemia, SHBG and lipids in PCOS patients
    D Cibula
    Department of Obstetrics and Gynecology, Charles University, Apolinarska 18, Prague 2, 120 00, Czech Republic
    Hum Reprod 20:180-4. 2005
    ..Neither oral contraceptives (COC) nor metformin are an optimal modality for the long-term treatment of polycystic ovary syndrome (PCOS). The aim of this study was to evaluate whether a combination of both is beneficial over COC monotherapy...
  25. doi request reprint Local control after tailored surgical treatment of early cervical cancer
    David Cibula
    Gynecological Oncology Centre, Department of Obstetrics and Gynecology, First Faculty of Medicine and General University Hospital, Charles University, Prague, Czech Republic
    Int J Gynecol Cancer 21:690-8. 2011
    ..It was the aim of our study to analyze oncological outcome and prognostic parameters in patients with early stages cervical cancer after tailored and well-standardized surgical treatment with an adequate follow-up...
  26. doi request reprint New classification system of radical hysterectomy: emphasis on a three-dimensional anatomic template for parametrial resection
    D Cibula
    Gynecologic Oncology Centre, Department of Obstetrics and Gynaecology, General University Hospital, First Medical School, Charles University, Prague, Czech Republic
    Gynecol Oncol 122:264-8. 2011
    ..However, it does not include a description of parametrial resection in three dimensions, which mostly determines post-operative morbidity...
  27. ncbi request reprint Does obesity diminish the positive effect of oral contraceptive treatment on hyperandrogenism in women with polycystic ovarian syndrome?
    D Cibula
    Department of Obstetrics and Gynecology, General Faculty Hospital, Charles University, Prague 2, Czech Republic
    Hum Reprod 16:940-4. 2001
    ..In conclusion, the positive effect of COC treatment on androgen production, serum androgen binding capacity, and clinical androgenic symptoms was negatively influenced by an increased BMI...
  28. doi request reprint Current clinical practice in cytoreductive surgery for advanced ovarian cancer: a European survey
    David Cibula
    Department of Obstetrics and Gynaecology, General University Hospital, Charles University, Prague, Czech Republic
    Int J Gynecol Cancer 21:1219-24. 2011
    ..Surgical treatment of advanced ovarian cancer is a subject of fast development. The aim of this survey was to collect data on current surgical treatment from selected European gynecological oncology centers...
  29. doi request reprint High-risk human papillomavirus DNA in paraaortic lymph nodes in advanced stages of cervical carcinoma
    Jiri Slama
    General Teaching Hospital and 1st Medical School of Charles University, Department of Oncogynecology, Apolinarska 18, 128 00 Prague 2, Czech Republic
    J Clin Virol 50:46-9. 2011
    ..Recent studies have confirmed the association of HPV DNA in pelvic lymph nodes in early-stage disease with metastatic involvement and a less favourable prognosis...
  30. doi request reprint Human papillomavirus DNA presence in pelvic lymph nodes in cervical cancer
    Jiri Slama
    Department of Oncogynecology, General Teaching Hospital and 1st Medica School of Charles University, Apolinarska 18, 128 00 Prague 2, Czech Republic
    Int J Gynecol Cancer 20:126-32. 2010
    ....
  31. doi request reprint High-risk human papillomavirus DNA in the primary tumor, sentinel, and nonsentinel pelvic lymph nodes in patients with early-stage cervical cancer: a correlation with histopathology
    Jiri Slama
    General Teaching Hospital, Department of Oncogynecology, 1st Medical School of Charles University, Prague 2, Czech Republic
    Int J Gynecol Cancer 19:703-7. 2009
    ..The presence of human papillomavirus (HPV) DNA in histologically negative pelvic nodes is considered a subclinical metastatic spread...
  32. doi request reprint Prevalence of nonclassic adrenal hyperplasia (NCAH) in hyperandrogenic women
    Michael Fanta
    Dept of Gynecology and Obstetrics, 1st Medical Faculty of Charles University and General Faculty Hospital, Praha 2, Czech Republic
    Gynecol Endocrinol 24:154-7. 2008
    ....
  33. doi request reprint Impaired glucose metabolism in women with polycystic ovary syndrome
    Jana Vrbikova
    Institute of Endocrinology, General Faculty Hospital, Charles University, Prague, Czech Republic
    Gynecol Obstet Invest 68:186-90. 2009
    ..To compare the prevalence of impaired glucose tolerance (IGT) and type 2 diabetes mellitus (T2DM) in lean and overweight/obese women with polycystic ovary syndrome (PCOS), with the data from a normal population sample...
  34. ncbi request reprint Prevalence of insulin resistance and prediction of glucose intolerance and type 2 diabetes mellitus in women with polycystic ovary syndrome
    Jana Vrbikova
    Institute of Endocrinology, Prague, Czech Republic
    Clin Chem Lab Med 45:639-44. 2007
    ..We evaluated the sensitivity and specificity of clinical and fasting biochemical parameters in screening for impaired glucose tolerance (IGT) and DM2...
  35. ncbi request reprint Comparison of the insulin action parameters from hyperinsulinemic clamps with homeostasis model assessment and QUICKI indexes in subjects with different endocrine disorders
    Jan Skrha
    Third Department of Internal Medicine, First Faculty of Medicine, Charles University, 128 08 Prague 2, Czech Republic
    J Clin Endocrinol Metab 89:135-41. 2004
    ..The HOMA and QUICKI indexes do not offer the same information as glucose clamps in the rare cases with differently impaired peripheral or hepatic insulin action...
  36. ncbi request reprint Low-density lipoprotein receptor-related protein-5 C/T polymorphism in exon 18 is associated with C peptide and proinsulin levels in control women and patients with polycystic ovary syndrome
    Bela Bendlova
    Institute of Endocrinology, Charles University, Prague, Czech Republic
    Fertil Steril 90:699-708. 2008
    ..The low-density lipoprotein receptor-related protein-5 gene has been found to play a role in determining insulin secretion in animal models...
  37. doi request reprint Pelvic lymphadenectomy improves survival in patients with cervical cancer with low-volume disease in the sentinel node: a retrospective multicenter cohort study
    Afra Zaal
    Division of Woman and Baby, Department of Gynaecological Oncology, University Medical Center Utrecht, Utrecht, The Netherlands Department of Obstetrics and Gynecology, Gynecological Oncology Centre, First Faculty of Medicine and General University Hospital, Charles University, Prague Institute of Biostatistics and Analyses, Masaryk University, Brno, Czech Republic Institut Claudius Regaud, Toulouse Université Paris Descartes, Sorbonne Paris Cité, Assistance Publique Hopitaux de Paris, European Georges Pompidou Teaching Hospital, Paris, France Jagiellonian University Medical College, Krakow, Poland University Hospital Ostrava, Ostrava, Czech Republic and Center for Gynaecologic Oncology Amsterdam, VU University Medical Center, Amsterdam, The Netherlands
    Int J Gynecol Cancer 24:303-11. 2014
    ..In this study, we aimed to describe the value of pelvic lymph node dissection (LND) after sentinel lymph node (SN) biopsy in early-stage cervical cancer...
  38. pmc Diagnosis, treatment, and follow-up of borderline ovarian tumors
    Daniela Fischerova
    Gynecological Oncology Center, Department of Obstetrics and Gynecology, Apolinaska 18, 120 00 Prague, Czech Republic
    Oncologist 17:1515-33. 2012
    ..Current literature on this topic leads to a number of controversies that will be discussed thoroughly in this article, with the aim to provide recommendations for the clinical management of these patients...
  39. doi request reprint Primary pure large-cell neuroendocrine carcinoma of the ovary
    Pavel Dundr
    Department of Pathology, 1st Faculty of Medicine and General Teaching Hospital, Charles University, Studnickova 2, Prague 12800, Czech Republic
    Pathol Res Pract 204:133-7. 2008
    ..Cytokeratin 20 was positive focally. Primary large-cell neuroendocrine carcinoma of the ovary is a rare tumor. To the best of our knowledge, only 4 cases of a pure tumor of this type have been reported to date...
  40. ncbi request reprint Localization of the sentinel node of the upper outer breast quadrant in the axillary quadrants
    David Pavlista
    Department of Oncogynecology, Clinic of Obstetrics and Gynecology, 1st Medical Faculty, Charles University, and General Faculty Hospital, Apolinarska 18, Prague, 12801, Czech Republic
    Ann Surg Oncol 14:633-7. 2007
    ..In such cases, exact knowledge of the topography of the axilla and the most probable location of the SN may be crucial...
  41. ncbi request reprint An analysis of the relationship between insulin resistance and the activity of steroid C17,20-lyase and 3beta-hydroxysteroid dehydrogenase in ovaries and adrenals in women with polycystic ovary syndrome
    J Vrbíklová
    Institute of Endocrinology, Prague, Czech Republic
    Exp Clin Endocrinol Diabetes 108:455-62. 2000
    ..The authors conclude that insulin resistance and/or hyperinsulinemia is probably not the primary factor responsible for the exaggerated adrenal androgen secretion found in a great number of patients with PCOS...
  42. doi request reprint Umbilication is a strong predictor of high-grade cervical intraepithelial neoplasia
    Jiri Slama
    Gynecologic Oncology Centre, 1st Faculty of Medicine, Charles University and General University Hospital in Prague, Brno, Czech Republic
    J Low Genit Tract Dis 17:303-7. 2013
    ..This study aimed to assess the diagnostic value of the colposcopic feature of umbilication for detecting high-grade cervical intraepithelial neoplasia (CIN 2/3)...
  43. doi request reprint Hysteroscopic management of displaced levonorgestrel-releasing intrauterine system
    David Kuzel
    Department of Obstetrics and Gynaecology, Charles University, First Faculty of Medicine and General Faculty Hospital in Prague, Prague, Czech Republic
    J Obstet Gynaecol Res 39:1014-8. 2013
    ..This study was designed to evaluate feasibility and effectiveness of hysteroscopic intervention in the management of symptoms related to the displaced levonorgestrel-releasing intrauterine system (LNG-IUS)...
  44. doi request reprint Uterine tumors with neuroectodermal differentiation. A report of 4 cases
    Pavel Dundr
    Department of Pathology, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Studnickova 2, Prague 128 00, Czech Republic
    Pathol Oncol Res 16:601-8. 2010
    ....
  45. doi request reprint Low-dose estrogen combined oral contraceptives may negatively influence physiological bone mineral density acquisition during adolescence
    David Cibula
    Department of Obstetrics and Gynecology, Faculty of Medicine 1, Charles University, Prague, Czech Republic
    Eur J Endocrinol 166:1003-11. 2012
    ..The aim was to evaluate changes of bone mineral density (BMD) and markers of bone turnover in healthy adolescents, and in adolescent users of combined oral contraceptives (COCs) with different ethinylestradiol (EE) contents...
  46. doi request reprint Primary synovial sarcoma of the uterus
    Pavel Dundr
    Department of Pathology, First Faculty of Medicine and General University Hospital, Charles University in Prague, Studnickova 2, Prague 2, 12800, Czech Republic
    Pathol Oncol Res 18:529-33. 2012
    ..At present, the patient shows no signs of tumor relapse 56 months after the diagnosis. To the best of our knowledge, this is the first report of synovial sarcoma arising in uterus...
  47. doi request reprint Comparative analysis of loss of heterozygosity and expression profile in normal tissue, DCIS and invasive breast cancer
    Michal Zikan
    Oncogynecologic Center, Department of Obstetrics and Gynecology, Charles University in Prague, First Faculty of Medicine and General University Hospital, Apolinarska 18, Prague 2, Czech Republic
    Clin Transl Oncol 13:652-5. 2011
    ....
  48. ncbi request reprint Novel complex genomic rearrangement of the BRCA1 gene
    Michal Zikan
    Department of Biochemistry and Experimental Oncology, First Medical School of Charles University, U nemocnice 5, 128 00, Prague, Czech Republic
    Mutat Res 637:205-8. 2008
    ..This rearrangement involves exons 21 and 22 and results in a protein product lacking BRCT domain important for its function...
  49. ncbi request reprint Oral but not transdermal estrogen replacement therapy reduced level of tissue factor pathway inhibitor: cross-over designed study
    Tomas Fait
    Department of Obstetrics and Gynaecology, General Faculty Hospital Prague and 1st Faculty of Medicine, Charles University, Czech Republic
    Neuro Endocrinol Lett 27:665-8. 2006
    ..The purpose of the present study was to determine changes of biochemical risk factors of thromboembolism especially of TFPI during the use of oral versus transdermal administration of early estrogen replacement therapy...
  50. doi request reprint Surgical education and training in gynecologic oncology I: European perspective
    David Cibula
    Department of Obstetrics and Gynecology, Oncogynecological Center, General Teaching Hospital, 1st Medical Faculty, Charles University, Apolinarska 18, Prague 2, Czech Republic
    Gynecol Oncol 114:S52-5. 2009
    ....
  51. doi request reprint Abortions and contraception use among Czech and Romanian women: comparison of representative national studies
    Kateřina Hollá
    First Medical Faculty, Charles University Department of Sexology, Prague, Czech Republic
    J Sex Med 8:1083-91. 2011
    ..This article presents the results of representative national studies comparing the behavior and attitudes of Czech and Romanian women regarding abortion and contraception use...
  52. ncbi request reprint The effects of long-term metformin treatment on adrenal and ovarian steroidogenesis in women with polycystic ovary syndrome
    J Vrbikova
    Institute of Endocrinology, Prague, Czech Republic
    Eur J Endocrinol 144:619-28. 2001
    ..To evaluate adrenal and ovarian steroidogenesis before and after long-term treatment with metformin in women with polycystic ovary syndrome (PCOS)...
  53. ncbi request reprint Acute exacerbation of recurrent pelvic inflammatory disease. Laparoscopic findings in 141 women with a clinical diagnosis
    D Cibula
    Department of Obstetrics and Gynecology, General Teaching Hospital, 1st Medical Faculty of Charles University, , Prague 2, 120 00, Czech Republic
    J Reprod Med 46:49-53. 2001
    ..CONCLUSION: Recurrent clinical symptoms and laboratory signs of PID should be an indication for confirming or excluding the clinical diagnosis by laparoscopy...
  54. ncbi request reprint Metabolic syndrome in young Czech women with polycystic ovary syndrome
    J Vrbikova
    Institute of Endocrinology, Narodni 8, Prague 1, 116 94 Czech Republic, Department of Obstetrics and Gynecology, Charles University, Apolinárská 28, Prague 2, 120 00 Czech Republic
    Hum Reprod 20:3328-32. 2005
    ..3 +/- 4.8 kg/m2; mean 6 SD] and 73 age-matched healthy females (BMI 22.3 +/- 3.3 kg/m2; mean +/- SD) were evaluated for the occurrence of features of metabolic syndrome according to the Adult Treatment Panel III...
  55. doi request reprint Decreased concentrations of retinol-binding protein 4 in sera of epithelial ovarian cancer patients: a potential biomarker identified by proteomics
    Lucie Lorkova
    Institute of Pathological Physiology, Department of Gynecology and Obstetrics, First Faculty of Medicine, Charles University, Prague, Czech Republic
    Oncol Rep 27:318-24. 2012
    ..We propose a connection of RBP4 with epithelial ovarian cancer and advocate the potential of RBP4 as a candidate diagnostic or prognostic biomarker...
  56. doi request reprint Contraceptive behaviour of Czech and Romanian women: comparison of representative national samples
    Pavlína Gregorová
    First Medical Faculty, Charles University, Department of Sexology, Prague, Czech Republic Gona, Sexological Centre, Prague, Czech Republic
    Eur J Obstet Gynecol Reprod Biol 154:163-6. 2011
    ..To investigate the contraceptive behaviour of Czech and Romanian women and their attitudes towards different forms of contraception...
  57. ncbi request reprint Reinstatement of serum pregnanolone isomers and progesterone during alcohol detoxification therapy in premenopausal women
    Martin Hill
    Institute of EndocrinologyCharles University, Prague, Czech Republic
    Alcohol Clin Exp Res 29:1010-7. 2005
    ....
  58. ncbi request reprint Transrectal ultrasound and magnetic resonance imaging in staging of early cervical cancer
    D Fischerova
    Department of Obstetrics and Gynecology, Oncogynecological Center, General Teaching Hospital, Charles University, Prague, Czech Republic
    Int J Gynecol Cancer 18:766-72. 2008
    ..TRUS and the pathology-derived volumes correlated tightly; accuracy of TRUS was superior to MRI, especially in detection of residual tumors following conization...
  59. doi request reprint Sexual morbidity following radical hysterectomy for cervical cancer
    P Vrzackova
    First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Apolinarska 4, 128 08, Prague 2, Czech Republic
    Expert Rev Anticancer Ther 10:1037-42. 2010
    ..The goal of this article is to summarize and discuss available relevant data on FSD in women who have undergone radical hysterectomy for an early stage of cervical cancer...
  60. ncbi request reprint Pregnancy outcome in women with PCOS and in controls matched by age and weight
    L Haakova
    Department of Obstetrics and Gynecology, Charles University and the General Faculty Hospital, Apolinarska 18, Prague 2, 120 00, Czech Republic
    Hum Reprod 18:1438-41. 2003
    ..The aim of this study was to compare the pregnancy outcome, especially the prevalence of gestational diabetes mellitus (GDM), in a group of patients with polycystic ovary syndrome (PCOS), with a group of healthy weight-matched women...
  61. ncbi request reprint Ultrasound-guided tru-cut biopsy in the management of advanced abdomino-pelvic tumors
    D Fischerova
    Departments of Obstetrics and Gynecology and Pathology, General Faculty Hospital, Charles University, Prague, Czech Republic
    Int J Gynecol Cancer 18:833-7. 2008
    ..It should, therefore, be considered as a method of choice for histologic verification of both advanced primary and recurrent abdomino-pelvic tumors...
  62. ncbi request reprint [Screening for factor V Leiden mutation in women using combined hormonal contraceptives or hormone replacement therapy]
    D Cibula
    Gynekologicko porodnická klinika 1 LF UK a VFN v Praze
    Ceska Gynekol 68:167-74. 2003
    ..Analysis of the issue of screening for Factor V Leiden mutation (FVL) in users of combined oral contraceptives (COC) or hormone replacement therapy (HRT)...
  63. ncbi request reprint [Effect of insulin in polycystic ovary syndrome]
    G Sindelka
    III interni klinika 1 LF UK a VFN, Praha
    Cas Lek Cesk 141:769-72. 2002
    ..The aim of this study was to compare the insulin action between thin and obese women with PCOS and to analyse its relationship to serum concentration of selected hormones...
  64. ncbi request reprint [Consensus statement regarding indications for Leiden (FVL-factor V Leiden) mutation determination when recommending combined hormonal contraception or hormone replacement therapy]
    D Cibula
    Gynekologicko porodnická klinika 1 lékarské fakulty UK a VFN, Praha
    Vnitr Lek 49:502. 2003
  65. ncbi request reprint Combined oral contraceptives in the treatment of polycystic ovary syndrome
    J Vrbikova
    Department of Clinical Endocrinology, Institute of Endocrinology, Narodni 8, Prague 1, 116 94, Czech Republic
    Hum Reprod Update 11:277-91. 2005
    ..The combination of COC and GnRH analogues is not superior to COC therapy alone. Prospective data about the influence of COC on the risk of diabetes mellitus, coronary artery disease and endometrial cancer in PCOS women are lacking...
  66. ncbi request reprint [Radical parametrectomy in women with invasive cervix cancer after previous simple hysterectomy]
    D Cibula
    Gynekologicko porodnicka klinika, 1 LF UK a VFN, Praha
    Ceska Gynekol 71:122-6. 2006
    ..Evaluate technique, indications and limits of surgical procedure in the treatment of cervical cancer diagnosed from uterus specimen from simple hysterectomy...
  67. ncbi request reprint [Recommendations for hormonal therapy and substitution]
    P Cepicky
    Gynekologicko porodnická ambulance LEVRET s r o, Praha
    Ceska Gynekol 71:150-2. 2006
  68. ncbi request reprint [Contribution of neoadjuvant chemotherapy for operability of cancers of the uterine cervix]
    J Slama
    Gynekologicko porodnická klinika VFN a 1 LF UK, Praha
    Ceska Gynekol 72:116-9. 2007
    ..To compare per-operative and post-operative morbidity in patients undergoing radical surgery for carcinoma of the uterine cervix after administration of a neoadjuvant chemotherapy, and for primarily small cervical tumour...
  69. ncbi request reprint [Recommendations for hormone replacement therapy in perimenopause and postmenopause]
    P Cepicky
    Gynekologicko porodnická ambulance LEVRET s r o, Praha
    Ceska Gynekol 68:125-7. 2003
  70. ncbi request reprint [Abdominal radical trachelectomy--technique and experience]
    D Cibula
    Gynekologicko porodnická klinika I, LF UK a VFN, Praha
    Ceska Gynekol 70:117-22. 2005
    ..Discussion of current experiences with abdominal radical trachelectomy in the treatment of early stages of cervical cancer in fertile women...