Jaromir Hubalek

Summary

Affiliation: Brno University of Technology
Country: Czech Republic

Publications

  1. pmc Voltammetry as a Tool for Characterization of CdTe Quantum Dots
    Pavlina Sobrova
    Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University in Brno, Zemedelska 1, CZ 613 00 Brno, Czech Republic
    Int J Mol Sci 14:13497-510. 2013
  2. pmc Carbon composite micro- and nano-tubes-based electrodes for detection of nucleic acids
    Jan Prasek
    Department of Microelectronics, Brno University of Technology, Technicka 10, CZ 61600 Brno, Czech Republic
    Nanoscale Res Lett 6:385. 2011
  3. doi request reprint Paramagnetic particles coupled with an automated flow injection analysis as a tool for influenza viral protein detection
    Ludmila Krejcova
    Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University in Brno, Czech Republic, European Union
    Electrophoresis 33:3195-204. 2012
  4. doi request reprint Mammalian metallothioneins: properties and functions
    Petr Babula
    Central European Institute of Technology, Brno University of Technology, Technicka 3058 10, CZ 616 00 Brno, Czech Republic
    Metallomics 4:739-50. 2012
  5. pmc Bio-sensing of cadmium(II) ions using Staphylococcus aureus
    Jiri Sochor
    Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University in Brno, Zemedelska 1, CZ 613 00 Brno, Czech Republic
    Sensors (Basel) 11:10638-63. 2011
  6. pmc Electrochemical microsensors for the detection of cadmium(II) and lead(II) ions in plants
    Olga Krystofova
    Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University in Brno, Zemedelska 1, CZ 613 00 Brno, Czech Republic
    Sensors (Basel) 10:5308-28. 2010
  7. pmc Modern micro and nanoparticle-based imaging techniques
    Marketa Ryvolova
    Central European Institute of Technology, Brno University of Technology, Brno, Czech Republic
    Sensors (Basel) 12:14792-820. 2012
  8. doi request reprint Glutathione modified CdTe quantum dots as a label for studying DNA interactions with platinum based cytostatics
    Marketa Ryvolova
    Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University in Brno, Brno, Czech Republic
    Electrophoresis 34:801-8. 2013
  9. pmc Development of a magnetic electrochemical bar code array for point mutation detection in the H5N1 neuraminidase gene
    Ludmila Krejcova
    Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University in Brno, Zemedelska 1, Brno CZ 61300, Czech Republic
    Viruses 5:1719-39. 2013
  10. pmc Tissue specific electrochemical fingerprinting
    Pavlina Sobrova
    Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University in Brno, Brno, Czech Republic
    PLoS ONE 7:e49654. 2012

Collaborators

  • Rene Kizek
  • Libuse Trnkova
  • Jiri Sochor
  • Marie Stiborova
  • Anna Vasku
  • Miroslav Pohanka
  • Vojtech Adam
  • Marketa Ryvolova
  • Jana Drbohlavova
  • Ondrej Zitka
  • Dalibor Huska
  • Sona Krizkova
  • Tomas Eckschlager
  • Jana Chomoucka
  • Petr Babula
  • Ludmila Krejcova
  • Michal Masarik
  • Pavlina Sobrova
  • David Hynek
  • Pavel Kopel
  • Jaromir Gumulec
  • Olga Krystofova
  • Ales Horna
  • Ladislav Havel
  • Kristyna Smerkova
  • Marketa Vaculovicova
  • Natalia Cernei
  • Miguel Angel Merlos Rodrigo
  • Ivo Provaznik
  • Jan Prasek
  • Josef Zehnalek
  • Radim Hrdy
  • Miroslava Beklova
  • Vaclav Diopan
  • Sylvie Skalickova
  • Jiri Vyslouzil
  • Jiri Sedlacek
  • Marketa Sztalmachova
  • Jarmila Kruseova
  • Nuria Ferrol
  • Lenka Vyslouzilova
  • Dana Dospivova
  • Olga Stepankova
  • Marina Vorozhtsova
  • Miguel Angel Merlos
  • Jozef Kaiser
  • Ota Salyk
  • Helena Skutkova
  • Jiri Anyz
  • Lenka Zajickova
  • Libor Janu
  • Petr Majzlik
  • Ondrej Jasek
  • David Vajtr
  • Jiri Baloun
  • Ladislav Zeman
  • Ivo Fabrik
  • Oldrich Schneeweiss
  • Violetta Shestivska
  • Margita Dvorska
  • Milan Zemlicka

Detail Information

Publications30

  1. pmc Voltammetry as a Tool for Characterization of CdTe Quantum Dots
    Pavlina Sobrova
    Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University in Brno, Zemedelska 1, CZ 613 00 Brno, Czech Republic
    Int J Mol Sci 14:13497-510. 2013
    ..Based on the convincing results, a new method for how to study stability and quantify the dots was suggested. Thus, the approach was further utilized for the testing of QDs stability. ..
  2. pmc Carbon composite micro- and nano-tubes-based electrodes for detection of nucleic acids
    Jan Prasek
    Department of Microelectronics, Brno University of Technology, Technicka 10, CZ 61600 Brno, Czech Republic
    Nanoscale Res Lett 6:385. 2011
    ..Other interesting result is the fact that we were able to distinguish signals for all bases using this electrode...
  3. doi request reprint Paramagnetic particles coupled with an automated flow injection analysis as a tool for influenza viral protein detection
    Ludmila Krejcova
    Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University in Brno, Czech Republic, European Union
    Electrophoresis 33:3195-204. 2012
    ..Cadmium was present in detectable amounts of 10 ng per mg of protein. Using this method, submicrogram concentrations of viral proteins can be identified...
  4. doi request reprint Mammalian metallothioneins: properties and functions
    Petr Babula
    Central European Institute of Technology, Brno University of Technology, Technicka 3058 10, CZ 616 00 Brno, Czech Republic
    Metallomics 4:739-50. 2012
    ....
  5. pmc Bio-sensing of cadmium(II) ions using Staphylococcus aureus
    Jiri Sochor
    Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University in Brno, Zemedelska 1, CZ 613 00 Brno, Czech Republic
    Sensors (Basel) 11:10638-63. 2011
    ..The results demonstrate potential in the application of microorganisms as modern biosensor systems based on biological components...
  6. pmc Electrochemical microsensors for the detection of cadmium(II) and lead(II) ions in plants
    Olga Krystofova
    Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University in Brno, Zemedelska 1, CZ 613 00 Brno, Czech Republic
    Sensors (Basel) 10:5308-28. 2010
    ....
  7. pmc Modern micro and nanoparticle-based imaging techniques
    Marketa Ryvolova
    Central European Institute of Technology, Brno University of Technology, Brno, Czech Republic
    Sensors (Basel) 12:14792-820. 2012
    ..Moreover the advantages of the drug delivery performed by nanocarriers such as iron oxides, gold, biodegradable polymers, dendrimers, lipid based carriers such as liposomes or micelles are also highlighted...
  8. doi request reprint Glutathione modified CdTe quantum dots as a label for studying DNA interactions with platinum based cytostatics
    Marketa Ryvolova
    Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University in Brno, Brno, Czech Republic
    Electrophoresis 34:801-8. 2013
    ..9511). As a conclusion, especially in the case of oxaliplatin-DNA adducts, the quenching was the most significant compared to cisplatin and nonquenching carboplatin...
  9. pmc Development of a magnetic electrochemical bar code array for point mutation detection in the H5N1 neuraminidase gene
    Ludmila Krejcova
    Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University in Brno, Zemedelska 1, Brno CZ 61300, Czech Republic
    Viruses 5:1719-39. 2013
    ..Moreover, the used biosensor exhibits sequence specificity and low limits of detection of subnanogram quantities of target nucleic acids...
  10. pmc Tissue specific electrochemical fingerprinting
    Pavlina Sobrova
    Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University in Brno, Brno, Czech Republic
    PLoS ONE 7:e49654. 2012
    ..The analysis of scientific data remains a big challenge, because each new task sets its specific requirements and constraints that call for the design of a targeted data pre-processing approach...
  11. pmc Silver(I) ions ultrasensitive detection at carbon electrodes-analysis of waters, tobacco cells and fish tissues
    Sona Krizkova
    Department of Chemistry and Biochemistry, Mendel University of Agriculture and Forestry, Zemedelska 1, CZ 613 00 Brno, Czech Republic
    Sensors (Basel) 9:6934-50. 2009
    ....
  12. doi request reprint Electrochemistry of copper(II) induced complexes in mycorrhizal maize plant tissues
    Ondrej Zitka
    Department of Chemistry and Biochemistry, Zemedelska 1, CZ 613 00 Brno, Czech Republic
    J Hazard Mater 203:257-63. 2012
    ..Rapid complex formation was determined under applied potentials 300, 500 and 600 mV during the measuring HDVs. It was also verified that mycorrhizal colonization reduced root to shoot translocation of Cu(II) ions...
  13. doi request reprint Microfluidic tool based on the antibody-modified paramagnetic particles for detection of 8-hydroxy-2'-deoxyguanosine in urine of prostate cancer patients
    Ondrej Zitka
    Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University in Brno, Brno, Czech Republic
    Electrophoresis 32:3207-20. 2011
    ..The optimized method had sufficient selectivity and thus could be used for determination of 8-OHDG in human urine and therefore for estimation of oxidative DNA damage as a result of oxidation stress in prostate cancer patients...
  14. ncbi request reprint From amino acids to proteins as targets for metal-based drugs
    Ondrej Zitka
    Department of Chemistry and Biochemistry, Mendel University in Brno, Czech Republic European Union
    Curr Drug Metab 13:306-20. 2012
    ..Special attention is paid to the application of nanotechnology-based techniques using these interactions for medical purposes such as diagnostics, imaging and therapy...
  15. ncbi request reprint Nanocarriers for anticancer drugs--new trends in nanomedicine
    Jana Drbohlavova
    Department of Microelectronics, Faculty of Electrical Engineering and Communication, Brno University of Technology, Brno, Czech Republic
    Curr Drug Metab 14:547-64. 2013
    ....
  16. doi request reprint Electrophoretic fingerprint metallothionein analysis as a potential prostate cancer biomarker
    Sona Krizkova
    Department of Chemistry and Biochemistry, Mendel University in Brno, Brno, Czech Republic
    Electrophoresis 32:1952-61. 2011
    ..To increase the throughput of the screening, chip-based capillary electrophoresis was suggested as a rapid and effective method for the fingerprinting analysis of prostate cancer from diseased blood sera...
  17. doi request reprint Protein-based electrochemical biosensor for detection of silver(I) ions
    Sona Krizkova
    Department of Chemistry and Biochemistry, Mendel University of Agriculture and Forestry, Zemedelska 1, Brno, Czech Republic
    Environ Toxicol Chem 29:492-6. 2010
    ..In the case of concentrations lower than 10 microM, the relative standard deviation increased to 10% (n = 8). The detection limit (3 signal/noise) for silver(I) ions was estimated as 500 nM...
  18. doi request reprint Fully automated spectrometric protocols for determination of antioxidant activity: advantages and disadvantages
    Jiri Sochor
    Department of Breeding and Propagation of Horticultural Plants, Faculty of Horticulture, Mendel University in Brno, Valticka 337, CZ 691 44 Lednice, Czech Republic
    Molecules 15:8618-40. 2010
    ..In contrary, the total time of manual spectrometric determination was approximately 120 min. The obtained data provided good correlations between studied methods (R=0.97-0.99)...
  19. doi request reprint Chip gel electrophoresis as a tool for study of matrix metalloproteinase 9 interaction with metallothionein
    Ondrej Zitka
    Department of Chemistry and Biochemistry, Mendel University in Brno, Brno, Czech Republic
    Electrophoresis 32:857-60. 2011
    ..It can be concluded that the activity of MMP-9 was higher in the presence of MT in comparison with the experimental collagen(type I)-MMP-9 mixture in vitro...
  20. pmc Study of Interactions between Metallothionein and Cisplatin by using Differential Pulse Voltammetry Brdickás reaction and Quartz Crystal Microbalance
    Dalibor Huska
    Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University of Agriculture and Forestry, Zemedelska 1, CZ 613 00 Brno, Czech Republic
    Sensors (Basel) 9:1355-69. 2009
    ..The formation of this complex was detectable even after a 20 s long interaction. Moreover, we detected presence of MT-cisplatin complex in the blood of male rats treated with this drug...
  21. doi request reprint Effect of sarcosine on antioxidant parameters and metallothionein content in the PC-3 prostate cancer cell line
    Natalia Cernei
    Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University in Brno, CZ 613 00 Brno, Czech Republic
    Oncol Rep 29:2459-66. 2013
    ..68 at p<0.001) and between DMPD and ABST (r=-0.64 at p<0.001). Additionally, as regards the correlation between MT and DPPH, a significant positive trend (r=0.62 at p<0.001) was observed...
  22. doi request reprint Magnetic nanoparticles and targeted drug delivering
    Jana Chomoucka
    Department of Microelectronics, Faculty of Electrical Engineering and Communication, Brno University of Technology, 602 00 Brno, Czech Republic
    Pharmacol Res 62:144-9. 2010
    ..This review summarizes the most commonly used functionalization methods of the MNPs preparation methods and their use in targeted drug delivery and targeted therapy...
  23. doi request reprint Biotin-modified glutathione as a functionalized coating for bioconjugation of CdTe-based quantum dots
    Marketa Ryvolova
    Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University in Brno, Brno, Czech Republic
    Electrophoresis 32:1619-22. 2011
    ..8 as a background electrolyte. The detection of sample components was performed by the photometric detection at 214 nm and LIF employing Ar⁺ ion laser (488 nm)...
  24. doi request reprint Electrochemical and spectrometric study of antioxidant activity of pomiferin, isopomiferin, osajin and catalposide
    Vaclav Diopan
    Department of Plant Biology, Faculty of Agronomy, Mendel University of Agriculture and Forestry Zemedelska 1, CZ 613 00 Brno, Czech Republic
    J Pharm Biomed Anal 48:127-33. 2008
    ..Based on the obtained results, pomiferin had the highest antioxidant activity followed by isopomiferin, osajin and catalposide...
  25. pmc Preparation and properties of various magnetic nanoparticles
    Jana Drbohlavova
    Department of Microelectronics, Faculty of Electrical Engineering and Communication, Brno University of Technology, Udolni 53, 602 00 Brno, Czech Republic E Mails R H J H
    Sensors (Basel) 9:2352-62. 2009
    ..g. detection of viral nucleic acids) and the phase purification of this sample for this purpose is not necessary...
  26. doi request reprint Automated nucleic acids isolation using paramagnetic microparticles coupled with electrochemical detection
    Dalibor Huska
    Department of Chemistry and Biochemistry, Mendel University of Agriculture and Forestry, Zemedelska 1, CZ 613 00 Brno, Czech Republic
    Talanta 79:402-11. 2009
    ..5h. Moreover, we applied the optimized procedure on fully automated pipetting instrument to isolate mRNA. The instrument was successfully tested on the analysis of extracts from roots of maize plants treated with cadmium(II) ions...
  27. doi request reprint Integrated chip electrophoresis and magnetic particle isolation used for detection of hepatitis B virus oligonucleotides
    Marketa Vaculovicova
    Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University in Brno, Brno, Czech Republic
    Electrophoresis 34:1548-54. 2013
    ..The commercial CE chip (Bio-rad) was successfully used to execute HBV fragment isolation. Detection using LIF with detection limit of 1 ng/mL was accomplished...
  28. doi request reprint Miniaturized electrochemical detector as a tool for detection of DNA amplified by PCR
    Dalibor Huska
    Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University of Agriculture and Forestry, Brno, Czech Republic
    Electrophoresis 29:4964-71. 2008
    ..Further the amplicons were loaded into agarose gel wells. DNA migrating to the detection place was electrochemically analyzed. Amplicons obtained after two cycles were detectable by this hyphenated technique...
  29. pmc Quantum dots - characterization, preparation and usage in biological systems
    Jana Drbohlavova
    Department of Microelectronics, Brno University of Technology, Czech Republic
    Int J Mol Sci 10:656-73. 2009
    ..This review reports on the recent methods for the preparation of quantum dots, their physical and chemical properties, surface modification as well as on some interesting examples of their experimental use...
  30. pmc Self-ordered TiO2 quantum dot array prepared via anodic oxidation
    Jana Drbohlavova
    Department of Microelectronics, Faculty of Electrical Engineering and Communication, Brno University of Technology, Technicka 10, Brno 61600, Czech Republic
    Nanoscale Res Lett 7:123. 2012
    ..Such heat-treated TiO2 QDs revealed a broad emission peak in the visible range (characterized by fluorescence spectroscopy)...