Affiliation: Academy of Sciences of the Czech Republic
Country: Czech Republic
Mares P, Kubova H. Changing effect of GABA B receptor antagonist CGP46381 after status epilepticus in immature rats. Epilepsy Res. 2018;149:17-20 pubmed publisher
..The interaction of the two GABAergic systems should be studied in detail. ..
MareÅ¡ P, KubovÃ¡ H. GABAB, not GABAA receptors play a role in cortical postictal refractoriness. Neuropharmacology. 2015;88:99-102 pubmed publisher
..Cooperation of different inhibitory systems is probably necessary to abolish postictal refractoriness in neocortex. This article is part of the Special Issue entitled 'GABAergic Signaling in Health and Disease'. ..
Kubova H, Mares P. Vigabatrin but not valproate prevents development of age-specific flexion seizures induced by N-methyl-D-aspartate (NMDA) in immature rats. Epilepsia. 2010;51:469-72 pubmed publisher
..Neither drug decreased NMDA-induced mortality, which occurred within approximately 15 min after NMDA administration and reached almost 100% in all groups. ..
Kubova H, Mares P. Are morphologic and functional consequences of status epilepticus in infant rats progressive?. Neuroscience. 2013;235:232-49 pubmed publisher
..In P12 rats, morphologic damage also tended to progress over time. Performance of animals in the Morris water maze correlated with the severity of damage, but not with seizure parameters. ..
Kubova H, Druga R, Lukasiuk K, Suchomelova L, Haugvicova R, Jirmanova I, et al
. Status epilepticus causes necrotic damage in the mediodorsal nucleus of the thalamus in immature rats. J Neurosci. 2001;21:3593-9 pubmed
Kubova H, Rejchrtová J, Redkozubova O, Mares P. Outcome of status epilepticus in immature rats varies according to the paraldehyde treatment. Epilepsia. 2005;46 Suppl 5:38-42 pubmed
..To test effects of paraldehyde on behavioral outcome of status epilepticus (SE) in developing rats...
Kubova H, Mares P. Partial agonist of benzodiazepine receptors Ro 19-8022 elicits withdrawal symptoms after short-term administration in immature rats. Physiol Res. 2012;61:319-23 pubmed
..No signs of hypersensitivity were seen at 4-day interval. There is a difference between immature and adult brain in an appearance of withdrawal symptom after administration of the partial agonist of benzodiazepine receptors Ro 19-8022. ..