Jaroslava Folbergrová

Summary

Affiliation: Academy of Sciences of the Czech Republic
Country: Czech Republic

Publications

  1. doi Brain superoxide anion formation in immature rats during seizures: protection by selected compounds
    Jaroslava Folbergrová
    Institute of Physiology, Academy of Sciences of the Czech Republic, v v i, Videnska 1083, 142 20 Prague 4, Czech Republic
    Exp Neurol 233:421-9. 2012
  2. ncbi Oxidative stress in immature brain following experimentally-induced seizures
    J Folbergrova
    Institute of Physiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic
    Physiol Res 62:S39-48. 2013
  3. doi Antioxidant enzymes in cerebral cortex of immature rats following experimentally-induced seizures: upregulation of mitochondrial MnSOD (SOD2)
    Jaroslava Folbergrová
    Institute of Physiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic
    Int J Dev Neurosci 31:123-30. 2013
  4. doi Sustained deficiency of mitochondrial complex I activity during long periods of survival after seizures induced in immature rats by homocysteic acid
    Jaroslava Folbergrová
    Institute of Physiology, Academy of Sciences of the Czech Republic, vvi, Videnska 1083, 142 20 Prague 4, Czech Republic
    Neurochem Int 56:394-403. 2010
  5. doi Posttreatment with group II metabotropic glutamate receptor agonist 2R,4R-4-aminopyrrolidine-2,4-dicarboxylate is only weakly effective on seizures in immature rats
    Jaroslava Folbergrová
    Institute of Physiology, v v i, Academy of Sciences of the Czech Republic, Videnska 1083, 142 20 Prague 4, Czech Republic
    Brain Res 1273:144-54. 2009
  6. doi Anticonvulsant and neuroprotective effect of (S)-3,4-dicarboxyphenylglycine against seizures induced in immature rats by homocysteic acid
    Jaroslava Folbergrová
    Institute of Physiology, Academy of Sciences of the Czech Republic, Videnska 1083, Prague 4, Czech Republic
    Neuropharmacology 54:665-75. 2008
  7. ncbi Mitochondrial complex I inhibition in cerebral cortex of immature rats following homocysteic acid-induced seizures
    Jaroslava Folbergrová
    Institute of Physiology, Academy of Sciences of the Czech Republic, Videnska 1083, 142 20 Prague 4, Czech Republic
    Exp Neurol 204:597-609. 2007
  8. ncbi Effect of free radical spin trap N-tert-butyl-alpha-phenylnitrone (PBN) on seizures induced in immature rats by homocysteic acid
    Jaroslava Folbergrová
    Institute of Physiology, Academy of Sciences of the Czech Republic, Videnska 1083, 14220 Prague 4, Czech Republic
    Exp Neurol 201:105-19. 2006
  9. ncbi Seizures induced in immature rats by homocysteic acid and the associated brain damage are prevented by group II metabotropic glutamate receptor agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate
    Jaroslava Folbergrová
    Institute of Physiology, Academy of Sciences of the Czech Republic, Videnska 1083, 142 20 Prague 4, Czech Republic
    Exp Neurol 192:420-36. 2005
  10. ncbi Seizures induced by homocysteic acid in immature rats are prevented by group III metabotropic glutamate receptoragonist (R,S)-4-phosphonophenylglycine
    Jaroslava Folbergrová
    Institute of Physiology, Academy of Sciences of the Czech Republic, Videnska 1083, 142 20 Prague 4, Czech Republic
    Exp Neurol 180:46-54. 2003

Detail Information

Publications13

  1. doi Brain superoxide anion formation in immature rats during seizures: protection by selected compounds
    Jaroslava Folbergrová
    Institute of Physiology, Academy of Sciences of the Czech Republic, v v i, Videnska 1083, 142 20 Prague 4, Czech Republic
    Exp Neurol 233:421-9. 2012
    ....
  2. ncbi Oxidative stress in immature brain following experimentally-induced seizures
    J Folbergrova
    Institute of Physiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic
    Physiol Res 62:S39-48. 2013
    ..It can be assumed that the substances with antioxidant properties combined with conventional therapies might provide a beneficial effect in treatment of epilepsy. ..
  3. doi Antioxidant enzymes in cerebral cortex of immature rats following experimentally-induced seizures: upregulation of mitochondrial MnSOD (SOD2)
    Jaroslava Folbergrová
    Institute of Physiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic
    Int J Dev Neurosci 31:123-30. 2013
    ....
  4. doi Sustained deficiency of mitochondrial complex I activity during long periods of survival after seizures induced in immature rats by homocysteic acid
    Jaroslava Folbergrová
    Institute of Physiology, Academy of Sciences of the Czech Republic, vvi, Videnska 1083, 142 20 Prague 4, Czech Republic
    Neurochem Int 56:394-403. 2010
    ....
  5. doi Posttreatment with group II metabotropic glutamate receptor agonist 2R,4R-4-aminopyrrolidine-2,4-dicarboxylate is only weakly effective on seizures in immature rats
    Jaroslava Folbergrová
    Institute of Physiology, v v i, Academy of Sciences of the Czech Republic, Videnska 1083, 142 20 Prague 4, Czech Republic
    Brain Res 1273:144-54. 2009
    ..Neurol.192, 420-436, 2005)...
  6. doi Anticonvulsant and neuroprotective effect of (S)-3,4-dicarboxyphenylglycine against seizures induced in immature rats by homocysteic acid
    Jaroslava Folbergrová
    Institute of Physiology, Academy of Sciences of the Czech Republic, Videnska 1083, Prague 4, Czech Republic
    Neuropharmacology 54:665-75. 2008
    ..The present findings suggest that receptor subtype 8 of group III mGluRs may be considered a promising target for drug therapy in childhood epilepsies in the future...
  7. ncbi Mitochondrial complex I inhibition in cerebral cortex of immature rats following homocysteic acid-induced seizures
    Jaroslava Folbergrová
    Institute of Physiology, Academy of Sciences of the Czech Republic, Videnska 1083, 142 20 Prague 4, Czech Republic
    Exp Neurol 204:597-609. 2007
    ..We can assume that inhibition of complex I may elicit enhanced formation of reactive oxygen species and contribute thus to neuronal injury demonstrated in this model...
  8. ncbi Effect of free radical spin trap N-tert-butyl-alpha-phenylnitrone (PBN) on seizures induced in immature rats by homocysteic acid
    Jaroslava Folbergrová
    Institute of Physiology, Academy of Sciences of the Czech Republic, Videnska 1083, 14220 Prague 4, Czech Republic
    Exp Neurol 201:105-19. 2006
    ..Free radical scavenger PBN had a clear-cut protective effect, evident as the improved recovery of brain energy status and as a partial, but significant, attenuation of neuronal degeneration associated with this model of seizures...
  9. ncbi Seizures induced in immature rats by homocysteic acid and the associated brain damage are prevented by group II metabotropic glutamate receptor agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate
    Jaroslava Folbergrová
    Institute of Physiology, Academy of Sciences of the Czech Republic, Videnska 1083, 142 20 Prague 4, Czech Republic
    Exp Neurol 192:420-36. 2005
    ..The present findings support the possibility that group II mGluRs are a promising target for a novel approach to treating epilepsy...
  10. ncbi Seizures induced by homocysteic acid in immature rats are prevented by group III metabotropic glutamate receptoragonist (R,S)-4-phosphonophenylglycine
    Jaroslava Folbergrová
    Institute of Physiology, Academy of Sciences of the Czech Republic, Videnska 1083, 142 20 Prague 4, Czech Republic
    Exp Neurol 180:46-54. 2003
    ..The present findings suggest that group III mGlu receptor agonists may be of therapeutic significance for treating childhood epilepsies...
  11. ncbi Attenuation of seizures induced by homocysteic acid in immature rats by metabotropic glutamate group II and group III receptor agonists
    J Folbergrova
    Institute of Physiology, Academy of Sciences of the Czech Republic, Videnska 1083, 142 20 Prague 4, Czech Republic
    Brain Res 908:120-9. 2001
    ..Higher doses of (S)-4-C3HPG (1--100 nmol) were, however, less anticonvulsant than low doses. The present results have confirmed that mGluRs may be considered a potential target for treatment of epilepsy...
  12. ncbi Neuronal cell death in hippocampus induced by homocysteic acid in immature rats
    Milos Langmeier
    Institute of Physiology, First Medical School, Charles University, Prague, Czech Republic
    Epilepsia 44:299-304. 2003
    ..To examine the morphologic alterations in the cerebral cortex and hippocampus of immature rats 6 days after the generalized clonic-tonic seizures induced by homocysteic acid (HCA)...
  13. doi Mitochondrial dysfunction in epilepsy
    Jaroslava Folbergrová
    Department of Developmental Epileptology, Institute of Physiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic
    Mitochondrion 12:35-40. 2012
    ..For this reason mitochondria have to be considered as promising targets for neuroprotective strategies in epilepsy...