Carsten W Lederer

Summary

Affiliation: The Cyprus Institute of Neurology and Genetics
Country: Cyprus

Publications

  1. ncbi request reprint Motor protein KIFC5A interacts with Nubp1 and Nubp2, and is implicated in the regulation of centrosome duplication
    Andri Christodoulou
    Department of Biological Sciences, University of Cyprus and Cyprus Institute of Neurology and Genetics, PO Box 20537, 1678 Nicosia, Cyprus
    J Cell Sci 119:2035-47. 2006
  2. pmc Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis
    Carsten W Lederer
    Department of Biological Sciences, University of Cyprus and Cyprus Institute of Neurology and Genetics, 1678 Nicosia, Cyprus
    BMC Genomics 8:26. 2007
  3. doi request reprint An electronic infrastructure for research and treatment of the thalassemias and other hemoglobinopathies: the Euro-mediterranean ITHANET project
    Carsten W Lederer
    Molecular Genetics Thalassaemia Department, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus
    Hemoglobin 33:163-76. 2009
  4. ncbi request reprint Differential expression of molecular motors in the motor cortex of sporadic ALS
    Maria Pantelidou
    Department of Biological Sciences, University of Cyprus and Cyprus Institute of Neurology and Genetics, P O Box 20537, 1678 Nicosia, Cyprus
    Neurobiol Dis 26:577-89. 2007
  5. doi request reprint Compounds of the anthracycline family of antibiotics elevate human gamma-globin expression both in erythroid cultures and in a transgenic mouse model
    Pandelis Spyrou
    Molecular Genetics Thalassaemia Department, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus
    Blood Cells Mol Dis 44:100-6. 2010
  6. ncbi request reprint Amyotrophic lateral sclerosis--the tools of the trait
    Carsten W Lederer
    Department of Biological Sciences, University of Cyprus and Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus
    Biotechnol J 2:608-21. 2007
  7. doi request reprint The nuclear ATPase/adenylate kinase hCINAP is recruited to perinucleolar caps generated upon RNA pol.II inhibition
    Anna Malekkou
    Department of Biological Sciences, University of Cyprus and Cyprus Institute of Neurology and Genetics, P O Box 20537, 1678 Nicosia, Cyprus
    FEBS Lett 584:4559-64. 2010

Detail Information

Publications7

  1. ncbi request reprint Motor protein KIFC5A interacts with Nubp1 and Nubp2, and is implicated in the regulation of centrosome duplication
    Andri Christodoulou
    Department of Biological Sciences, University of Cyprus and Cyprus Institute of Neurology and Genetics, PO Box 20537, 1678 Nicosia, Cyprus
    J Cell Sci 119:2035-47. 2006
    ..These results implicate KIFC5A and the Nubp proteins in a common regulatory pathway involved in the control of centrosome duplication in mammalian cells...
  2. pmc Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis
    Carsten W Lederer
    Department of Biological Sciences, University of Cyprus and Cyprus Institute of Neurology and Genetics, 1678 Nicosia, Cyprus
    BMC Genomics 8:26. 2007
    ..Moreover, the human motor cortex, although critical to ALS pathology and physiologically altered in most forms of the disease, has not been screened systematically for therapeutic targets...
  3. doi request reprint An electronic infrastructure for research and treatment of the thalassemias and other hemoglobinopathies: the Euro-mediterranean ITHANET project
    Carsten W Lederer
    Molecular Genetics Thalassaemia Department, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus
    Hemoglobin 33:163-76. 2009
    ..The ITHANET Portal as a web-based tool born out of this experience amends some of the problems encountered and facilitates education and international exchange of data and expertise for hemoglobinopathies...
  4. ncbi request reprint Differential expression of molecular motors in the motor cortex of sporadic ALS
    Maria Pantelidou
    Department of Biological Sciences, University of Cyprus and Cyprus Institute of Neurology and Genetics, P O Box 20537, 1678 Nicosia, Cyprus
    Neurobiol Dis 26:577-89. 2007
    ..No mutations causing splicing defects or altering protein-coding sequences were identified in the genes of the three proteins. The present study implicates two motor proteins as possible candidates in SALS pathology...
  5. doi request reprint Compounds of the anthracycline family of antibiotics elevate human gamma-globin expression both in erythroid cultures and in a transgenic mouse model
    Pandelis Spyrou
    Molecular Genetics Thalassaemia Department, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus
    Blood Cells Mol Dis 44:100-6. 2010
    ..In parallel, future studies of the epigenetic effects of the five anthracyclines on the beta-globin locus will generate possible mechanistic leads on the regulation of the globin genes...
  6. ncbi request reprint Amyotrophic lateral sclerosis--the tools of the trait
    Carsten W Lederer
    Department of Biological Sciences, University of Cyprus and Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus
    Biotechnol J 2:608-21. 2007
    ..In combination with a further subcategorization of patients and the development of corresponding model systems for functional analyses, they will significantly influence the already changing face of ALS therapy...
  7. doi request reprint The nuclear ATPase/adenylate kinase hCINAP is recruited to perinucleolar caps generated upon RNA pol.II inhibition
    Anna Malekkou
    Department of Biological Sciences, University of Cyprus and Cyprus Institute of Neurology and Genetics, P O Box 20537, 1678 Nicosia, Cyprus
    FEBS Lett 584:4559-64. 2010
    ..In DNCs, hCINAP co-localizes with Paraspeckle Protein (PSP1) and also co-segregates with PSP1, and not coilin, in nuclear and nucleolar foci upon UV irradiation...