Maria Paula Curado

..2) and females (13.5). The results provide an overview of oropharyngeal cancer incidence and constitute a basis for the development of primary and secondary prevention, according to geographical variations and topography...

..To describe and compare trends in leukemia mortality among children (0-14 years of age) and adolescents and young adults (AYA, 15-24 years of age) in 12 countries in Latin America during 1980-2004...

..02). These results implicate two variants at 4q21 and 12q24 and further highlight three ADH variants in UADT cancer susceptibility...

..We have evaluated the HPV deoxyribonucleic acid (DNA) prevalence as well as the association between serological response to HPV infection and HNSCC in two distinct populations from Central Europe (CE) and Latin America (LA)...

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..36, 95% CI = 0.16-0.83), but linear trends were not observed for the frequency or duration of any supplement intake. We did not observe any strong associations between vitamin or mineral supplement intake and the risk of HNC...

..This study identifies aberrant DNA methylation patterns in UADT cancers and suggests a potential mechanism by which environmental factors may deregulate key cellular genes involved in tumor suppression and contribute to UADT cancers...

..We studied the incidence of OCC in developed and in developing countries...

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..This study provides a proof of principle that genetic variation plays a role in antibody reactivity to HPV infection...

..The newer treatment modalities and screening programs have been developed to alleviate the burden of this disease, but much more needs to be done in the developing countries for the impact to reach outside of the developed nations...

..We have used data from the Gambian National Cancer Registry to compare trends in incidence of HCC in both genders...

..It points to the need for further studies on cancer determinants to improve prevention, early detection and therapeutic management of these diseases in a low-resource setting in West Africa...

..Sexual contact may be the means by which head and neck cancer patients are exposed to human papillomavirus (HPV)...

..However, it is unclear how many years must pass following cessation of these habits before the risk is reduced, and whether the risk ultimately declines to the level of never smokers or never drinkers...

..The magnitude of risk conferred by the interaction between tobacco and alcohol use on the risk of head and neck cancers is not clear because studies have used various methods to quantify the excess head and neck cancer burden...

..To test the hypothesis that bladder cancer is a heterogeneous disease...

..Indeed, factors other than HIV infection likely contribute to their geographical patterns...

..The incidence rates of cancer across Asia vary greatly, with approximately three fold differences in both males and females...

..In this study we investigated the feasibility of automatically retrieving information from the medical literature and leveraging this information in GWAS...

..A rise in incidence of intrahepatic cholangiocarcinoma has been recently reported in Western countries but comparatively little is known about recent cholangiocarcinoma incidence trends in East and South-Eastern Asia...

..To review the most recent epidemiological studies on head and neck cancer and changes in knowledge about risk factors. The main review concerned the squamous cell carcinoma of the oral cavity, oropharynx, larynx and hypopharynx...

..0002 and 0.065, respectively). Both gene effects were independent of each other, implying that multiple ADH genes may be involved in upper aerodigestive cancer etiology...

..Thus, hypermethylation of DOK1 is a potentially critical event in human carcinogenesis, and may be a potential cancer biomarker and an attractive target for epigenetic-based therapy...

..However, there are few recent descriptive reports on the epidemiology of breast cancer among Eastern and Southeastern Asian populations...