Cunha V, Santos M, Moradas Ferreira P, Ferreira M. Simvastatin effects on detoxification mechanisms in Danio rerio embryos. Environ Sci Pollut Res Int. 2016;23:10615-29 pubmed publisher
..In conclusion, our data revealed the interaction of simvastatin with detoxification mechanisms highlighting the importance of monitoring the presence of this emerging contaminant in aquatic environments. ..
Cunha V, Rodrigues P, Santos M, Moradas Ferreira P, Ferreira M. Danio rerio embryos on Prozac - Effects on the detoxification mechanism and embryo development. Aquat Toxicol. 2016;178:182-9 pubmed publisher
..These finding raises additional concerns supporting the need to monitor the presence of this compound in aquatic reservoirs. ..
Cunha V, Burkhardt Medicke K, Wellner P, Santos M, Moradas Ferreira P, Luckenbach T, et al
. Effects of pharmaceuticals and personal care products (PPCPs) on multixenobiotic resistance (MXR) related efflux transporter activity in zebrafish (Danio rerio) embryos. Ecotoxicol Environ Saf. 2017;136:14-23 pubmed publisher
..Furthermore, it appears that interference of PPCPs with efflux activity in zebrafish embryos is not only from effects on Abcb4 but also on other efflux transporter subtypes. ..
Cunha V, Rodrigues P, Santos M, Moradas Ferreira P, Ferreira M. Fluoxetine modulates the transcription of genes involved in serotonin, dopamine and adrenergic signalling in zebrafish embryos. Chemosphere. 2018;191:954-961 pubmed publisher
..Hence, evaluating the presence of this psychopharmaceutical in the aquatic environment should be implemented in future monitoring programmes. ..