Arlhee Diaz

Summary

Affiliation: Center of Molecular Immunology
Country: Cuba

Publications

  1. ncbi Functional expression of human-epidermal-growth-factor receptor in a melanoma cell line
    Arlhee Diaz
    Department of Experimental Immunotherapy, Center of Molecular Immunology, Havana, Cuba
    Biotechnol Appl Biochem 48:21-7. 2007
  2. ncbi Biological activity in vitro of anti-epidermal growth factor receptor monoclonal antibodies with different affinities
    Arlhee Diaz Miqueli
    Center of Molecular Immunology, Havana, Cuba
    Hybridoma (Larchmt) 26:423-31. 2007
  3. ncbi Radiosensitisation of U87MG brain tumours by anti-epidermal growth factor receptor monoclonal antibodies
    A Diaz Miqueli
    Department of Experimental Immunotherapy, Centre of Molecular Immunology, PO Box 16040, 214 Street, Havana 11600, Cuba
    Br J Cancer 100:950-8. 2009
  4. ncbi Interferon-alpha conditioned sensitivity to an anti-epidermal growth factor receptor monoclonal antibody in a human lung cancer cell line with intermediate expression of the receptor
    Arlhee Diaz
    Department of Experimental Immunotherapy, Centre of Molecular Immunology, Havana, Cuba
    J Interferon Cytokine Res 29:433-40. 2009
  5. ncbi Epidermal growth factor receptor modulates the tumorigenic potential of melanoma
    Arlhee Diaz
    Department of Experimental Immunotherapy, Center of Molecular Immunology, P O Box 16040, Havana 11600, Cuba
    Front Biosci 14:159-66. 2009

Collaborators

Detail Information

Publications5

  1. ncbi Functional expression of human-epidermal-growth-factor receptor in a melanoma cell line
    Arlhee Diaz
    Department of Experimental Immunotherapy, Center of Molecular Immunology, Havana, Cuba
    Biotechnol Appl Biochem 48:21-7. 2007
    ..Thus we have developed a system to express a functional EGFR in order to evaluate the potential contribution of EGFR expression in melanoma biology and its resulting relevance as a target for immunointerventions in nonepithelial tumours...
  2. ncbi Biological activity in vitro of anti-epidermal growth factor receptor monoclonal antibodies with different affinities
    Arlhee Diaz Miqueli
    Center of Molecular Immunology, Havana, Cuba
    Hybridoma (Larchmt) 26:423-31. 2007
    ..Our findings also confirm previous evidences that blocking EGFR in A431 cells by means of antibodies significantly changes tumor cell biology by promoting apoptosis while decreasing tumor cell proliferation...
  3. ncbi Radiosensitisation of U87MG brain tumours by anti-epidermal growth factor receptor monoclonal antibodies
    A Diaz Miqueli
    Department of Experimental Immunotherapy, Centre of Molecular Immunology, PO Box 16040, 214 Street, Havana 11600, Cuba
    Br J Cancer 100:950-8. 2009
    ..In addition, we first showed the ability of mAb specifics against EGFR to target radioresistant glioma CSC, supporting the potential use in patients...
  4. ncbi Interferon-alpha conditioned sensitivity to an anti-epidermal growth factor receptor monoclonal antibody in a human lung cancer cell line with intermediate expression of the receptor
    Arlhee Diaz
    Department of Experimental Immunotherapy, Centre of Molecular Immunology, Havana, Cuba
    J Interferon Cytokine Res 29:433-40. 2009
    ..In conclusion, this study may provide insights about the rational use of EGFR inhibitors into the immunopharmacological management of targeted therapies including the IFN-alpha for lung cancer...
  5. ncbi Epidermal growth factor receptor modulates the tumorigenic potential of melanoma
    Arlhee Diaz
    Department of Experimental Immunotherapy, Center of Molecular Immunology, P O Box 16040, Havana 11600, Cuba
    Front Biosci 14:159-66. 2009
    ..Moreover, the potential EGFR expression during the melanoma outgrowth that would be downregulated by interacting with the host immune system during the tumor evolution is not excluded and which may be dissected in this model...