Ana B Crujeiras

Summary

Publications

  1. doi request reprint Differential expression of oxidative stress and inflammation related genes in peripheral blood mononuclear cells in response to a low-calorie diet: a nutrigenomics study
    Ana B Crujeiras
    Department of Nutrition and Food Sciences, Physiology and Toxicology, University of Navarra, Pamplona, Spain
    OMICS 12:251-61. 2008
  2. ncbi request reprint Association between circulating irisin levels and the promotion of insulin resistance during the weight maintenance period after a dietary weight-lowering program in obese patients
    Ana B Crujeiras
    Laboratory of Molecular and Cellular Endocrinology, Instituto de Investigación Sanitaria IDIS, Complejo Hospitalario Universitario de Santiago CHUS and Santiago de Compostela University USC, Santiago de Compostela, Spain Cancer Epigenetics and Biology Program PEBC, Bellvitge Biomedical Research Institute IDIBELL, Barcelona, Spain CIBER Fisiopatología de la Obesidad y la Nutrición CIBEROBN, Madrid, Spain Electronic address
    Metabolism 63:520-31. 2014
  3. doi request reprint Pre-treatment circulating leptin/ghrelin ratio as a non-invasive marker to identify patients likely to regain the lost weight after an energy restriction treatment
    A B Crujeiras
    Laboratory of Molecular and Cellular Endocrinology, Instituto de Investigacion Sanitaria, Complejo Hospitalario Universitario de Santiago CHUS and Santiago de Compostela University USC, C Choupana, S N, 15706, Santiago de Compostela, Spain
    J Endocrinol Invest 37:119-26. 2014
  4. ncbi request reprint Association of weight regain with specific methylation levels in the NPY and POMC promoters in leukocytes of obese men: a translational study
    Ana B Crujeiras
    Cancer Epigenetics and Biology Program PEBC, Bellvitge Biomedical Research Institute IDIBELL, Spain Laboratory of Molecular and Cellular Endocrinology, Instituto de Investigación Sanitaria IDIS, Complejo Hospitalario Universitario de Santiago CHUS, Santiago de Compostela University USC, Spain CIBER Fisiopatología de la Obesidad y la Nutrición CIBEROBN, Spain Electronic address
    Regul Pept 186:1-6. 2013
  5. doi request reprint Oxidative stress associated to dysfunctional adipose tissue: a potential link between obesity, type 2 diabetes mellitus and breast cancer
    A B Crujeiras
    Cancer Epigenetics and Biology Program PEBC, Bellvitge Biomedical Research Institute, Barcelona, Spain
    Free Radic Res 47:243-56. 2013
  6. doi request reprint Association of breast cancer and obesity in a homogeneous population from Spain
    A B Crujeiras
    Laboratory of Molecular and Cellular Endocrinology, Instituto de Investigacion Sanitaria, Complejo Hospitalario de Santiago de Compostela, Santiago de Compostela, Spain
    J Endocrinol Invest 35:681-5. 2012
  7. doi request reprint Tachyphylaxis effects on postprandial oxidative stress and mitochondrial-related gene expression in overweight subjects after a period of energy restriction
    Ana B Crujeiras
    Department of Nutrition and Food Sciences, Physiology and Toxicology, University of Navarra, Pamplona, Spain
    Eur J Nutr 48:341-7. 2009
  8. doi request reprint Weight regain after a diet-induced loss is predicted by higher baseline leptin and lower ghrelin plasma levels
    Ana B Crujeiras
    Laboratory of Molecular and Cellular Endocrinology, Instituto de Investigació n Sanitaria, Complejo Hospitalario de Santiago and Santiago de Compostela University, Santiago de Compostela, Spain
    J Clin Endocrinol Metab 95:5037-44. 2010
  9. doi request reprint A nutrigenomic inflammation-related PBMC-based approach to predict the weight-loss regain in obese subjects
    Estibaliz Goyenechea
    Department of Nutrition and Food Science, Physiology and Toxicology, University of Navarra, Pamplona, Spain
    Ann Nutr Metab 54:43-51. 2009
  10. doi request reprint Expression of two inflammation-related genes (RIPK3 and RNF216) in mononuclear cells is associated with weight-loss regain in obese subjects
    Estibaliz Goyenechea
    Department of Nutrition and Food Sciences, Physiology and Toxicology, University of Navarra, Navarra, Spain
    J Nutrigenet Nutrigenomics 2:78-84. 2009

Collaborators

Detail Information

Publications16

  1. doi request reprint Differential expression of oxidative stress and inflammation related genes in peripheral blood mononuclear cells in response to a low-calorie diet: a nutrigenomics study
    Ana B Crujeiras
    Department of Nutrition and Food Sciences, Physiology and Toxicology, University of Navarra, Pamplona, Spain
    OMICS 12:251-61. 2008
    ..IL8 gene expression warrant further research as a putative novel biomarker of changes in body fat percentage in response to an LCD...
  2. ncbi request reprint Association between circulating irisin levels and the promotion of insulin resistance during the weight maintenance period after a dietary weight-lowering program in obese patients
    Ana B Crujeiras
    Laboratory of Molecular and Cellular Endocrinology, Instituto de Investigación Sanitaria IDIS, Complejo Hospitalario Universitario de Santiago CHUS and Santiago de Compostela University USC, Santiago de Compostela, Spain Cancer Epigenetics and Biology Program PEBC, Bellvitge Biomedical Research Institute IDIBELL, Barcelona, Spain CIBER Fisiopatología de la Obesidad y la Nutrición CIBEROBN, Madrid, Spain Electronic address
    Metabolism 63:520-31. 2014
    ..This study aimed to investigate the association between irisin and reduced insulin sensitivity induced by weight regain...
  3. doi request reprint Pre-treatment circulating leptin/ghrelin ratio as a non-invasive marker to identify patients likely to regain the lost weight after an energy restriction treatment
    A B Crujeiras
    Laboratory of Molecular and Cellular Endocrinology, Instituto de Investigacion Sanitaria, Complejo Hospitalario Universitario de Santiago CHUS and Santiago de Compostela University USC, C Choupana, S N, 15706, Santiago de Compostela, Spain
    J Endocrinol Invest 37:119-26. 2014
    ..Leptin and ghrelin appear to play a role in weight regain after a successful weight loss. The pre-treatment plasma levels of leptin/ghrelin ratio (L/G) could have power to predict this clinically relevant issue in the obesity treatment...
  4. ncbi request reprint Association of weight regain with specific methylation levels in the NPY and POMC promoters in leukocytes of obese men: a translational study
    Ana B Crujeiras
    Cancer Epigenetics and Biology Program PEBC, Bellvitge Biomedical Research Institute IDIBELL, Spain Laboratory of Molecular and Cellular Endocrinology, Instituto de Investigación Sanitaria IDIS, Complejo Hospitalario Universitario de Santiago CHUS, Santiago de Compostela University USC, Spain CIBER Fisiopatología de la Obesidad y la Nutrición CIBEROBN, Spain Electronic address
    Regul Pept 186:1-6. 2013
    ..Therefore, the study of leukocyte methylation levels reflects a putative epigenetic regulation of NPY and POMC, which might be implicated in the weight regain process and be used as biomarkers for predicting weight regain after dieting. ..
  5. doi request reprint Oxidative stress associated to dysfunctional adipose tissue: a potential link between obesity, type 2 diabetes mellitus and breast cancer
    A B Crujeiras
    Cancer Epigenetics and Biology Program PEBC, Bellvitge Biomedical Research Institute, Barcelona, Spain
    Free Radic Res 47:243-56. 2013
    ....
  6. doi request reprint Association of breast cancer and obesity in a homogeneous population from Spain
    A B Crujeiras
    Laboratory of Molecular and Cellular Endocrinology, Instituto de Investigacion Sanitaria, Complejo Hospitalario de Santiago de Compostela, Santiago de Compostela, Spain
    J Endocrinol Invest 35:681-5. 2012
    ..To evaluate for the first time in Spain if the association between obesity and breast cancer prognosis is similar to that reported in other countries with non Mediterranean dietary patterns...
  7. doi request reprint Tachyphylaxis effects on postprandial oxidative stress and mitochondrial-related gene expression in overweight subjects after a period of energy restriction
    Ana B Crujeiras
    Department of Nutrition and Food Sciences, Physiology and Toxicology, University of Navarra, Pamplona, Spain
    Eur J Nutr 48:341-7. 2009
    ..Postprandially induced oxidative stress can cause damage to mitochondrial components and initiate cellular degradative processes; which are related to obesity comorbidities...
  8. doi request reprint Weight regain after a diet-induced loss is predicted by higher baseline leptin and lower ghrelin plasma levels
    Ana B Crujeiras
    Laboratory of Molecular and Cellular Endocrinology, Instituto de Investigació n Sanitaria, Complejo Hospitalario de Santiago and Santiago de Compostela University, Santiago de Compostela, Spain
    J Clin Endocrinol Metab 95:5037-44. 2010
    ..Appetite-related hormones may play an important role in weight regain after obesity therapy...
  9. doi request reprint A nutrigenomic inflammation-related PBMC-based approach to predict the weight-loss regain in obese subjects
    Estibaliz Goyenechea
    Department of Nutrition and Food Science, Physiology and Toxicology, University of Navarra, Pamplona, Spain
    Ann Nutr Metab 54:43-51. 2009
    ..We investigated the role of the proinflammatory status on weight changes in obese subjects receiving a low-calorie diet (LCD) and during the subsequent 6-month weight maintenance period...
  10. doi request reprint Expression of two inflammation-related genes (RIPK3 and RNF216) in mononuclear cells is associated with weight-loss regain in obese subjects
    Estibaliz Goyenechea
    Department of Nutrition and Food Sciences, Physiology and Toxicology, University of Navarra, Navarra, Spain
    J Nutrigenet Nutrigenomics 2:78-84. 2009
    ..We analyzed the expression of two interacting genes (RIPK3 and RNF216) in obese subjects receiving a low-calorie diet (LCD) and during the subsequent weight changes...
  11. ncbi request reprint A hypocaloric diet enriched in legumes specifically mitigates lipid peroxidation in obese subjects
    Ana B Crujeiras
    Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
    Free Radic Res 41:498-506. 2007
    ....
  12. doi request reprint Enhanced short-term improvement of insulin response to a low-caloric diet in obese carriers the Gly482Ser variant of the PGC-1alpha gene
    Estibaliz Goyenechea
    Department of Nutrition and Food Science, Physiology and Toxicology, University of Navarra, Irunlarrea 1, 31008 Pamplona, Spain
    Diabetes Res Clin Pract 82:190-6. 2008
    ..The current study investigated the relationships of carrying this polymorphism with insulin resistance (IR) during a short-term weight-loss and the subsequent weight follow-up...
  13. ncbi request reprint A role for fruit content in energy-restricted diets in improving antioxidant status in obese women during weight loss
    Ana B Crujeiras
    Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
    Nutrition 22:593-9. 2006
    ..The aim of the present work was to estimate the ability of two hypocaloric diets with different fruit contents to improve antioxidant biomarkers related to lipid peroxidation in obese women...
  14. doi request reprint Longitudinal variation of circulating irisin after an energy restriction-induced weight loss and following weight regain in obese men and women
    Ana B Crujeiras
    Laboratory of Molecular and Cellular Endocrinology, Instituto de Investigación Sanitaria IDIS, Complejo Hospitalario Universitario de Santiago CHUS and Santiago de Compostela University USC, Santiago de Compostela, Spain Cancer Epigenetics and Biology Program PEBC, Bellvitge Biomedical Research Institute IDIBELL, Barcelona, Spain CIBER Fisiopatología de la Obesidad y la Nutrición CIBEROBN, Madrid, Spain
    Am J Hum Biol 26:198-207. 2014
    ..The objective of this work was to evaluate whether circulating human irisin levels are modulated by body size and changes in adiposity during an energy restriction treatment and the subsequent weight regain...
  15. pmc The gastric CB1 receptor modulates ghrelin production through the mTOR pathway to regulate food intake
    Lucía L Senín
    Grupo Fisiopatologia Endocrina, Instituto de Investigación Sanitaria de Santiago de Compostela IDIS, Complexo Hospitalario Universitario de Santiago CHUS SERGAS, Santiago de Compostela, Spain CIBER Fisiopatología Obesidad y Nutrición CB06 03, Instituto de Salud Carlos III, Santiago de Compostela, Spain
    PLoS ONE 8:e80339. 2013
    ..In conclusion, to the best of our knowledge, the present work is the first to describe a CB1 receptor-mediated mechanism that influences gastric ghrelin secretion and food intake through the mTOR pathway. ..
  16. pmc The obestatin/GPR39 system is up-regulated by muscle injury and functions as an autocrine regenerative system
    Uxía Gurriarán-Rodríguez
    Area de Endocrinología Molecular y Celular, Instituto de Investigación Sanitaria de Santiago IDIS, Santiago de Compostela, Spain
    J Biol Chem 287:38379-89. 2012
    ..These data elucidate a novel mechanism whereby the obestatin/GPR39 system is coordinately regulated as part of the myogenic program and operates as an autocrine signal regulating skeletal myogenesis...