P Sikiric

Summary

Affiliation: University of Zagreb
Country: Croatia

Publications

  1. ncbi request reprint Revised Robert's cytoprotection and adaptive cytoprotection and stable gastric pentadecapeptide BPC 157. Possible significance and implications for novel mediator
    Predrag Sikiric
    Department of Pharmacology, Medical Faculty University of Zagreb, Salata 11, POB 916, 10000 Zagreb, Croatia
    Curr Pharm Des 16:1224-34. 2010
  2. ncbi request reprint Stable Gastric Pentadecapeptide BPC 157-NO-system Relation
    Predrag Sikiric
    Department of Pharmacology, Medical Faculty University of Zagreb, Salata 11, POB 916, 10000 Zagreb, Croatia
    Curr Pharm Des 20:1126-35. 2014
  3. ncbi request reprint Stable gastric pentadecapeptide BPC 157 heals cysteamine-colitis and colon-colon-anastomosis and counteracts cuprizone brain injuries and motor disability
    R Klicek
    Department of Pharmacology, Medical Faculty, University of Zagreb, Zagreb, Croatia
    J Physiol Pharmacol 64:597-612. 2013
  4. ncbi request reprint Toxicity by NSAIDs. Counteraction by stable gastric pentadecapeptide BPC 157
    Predrag Sikiric
    Department of Pharmacology and Pathology, Medical Faculty University of Zagreb, Salata 11, POB 916, 10000 Zagreb, Croatia
    Curr Pharm Des 19:76-83. 2013
  5. ncbi request reprint Focus on ulcerative colitis: stable gastric pentadecapeptide BPC 157
    P Sikiric
    Department of Pharmacology, Medical Faculty University of Zagreb, Salata 11, POB 916, 10000 Zagreb, Croatia
    Curr Med Chem 19:126-32. 2012
  6. ncbi request reprint Pentadecapeptide BPC 157 attenuates chronic amphetamine-induced behavior disturbances
    Predrag Sikiric
    Department of Pharmacology, Medical Faculty University of Zagreb, Salata 11, POB 916, 10000 Zagreb, Croatia
    Acta Pharmacol Sin 23:412-22. 2002
  7. ncbi request reprint Corticosteroid-impairment of healing and gastric pentadecapeptide BPC-157 creams in burned mice
    P Sikiric
    Department of Pharmacology Medical Faculty, University of Zagreb, Salta 11, PO Box 916, Zagreb 10000, Croatia
    Burns 29:323-34. 2003
  8. ncbi request reprint Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract
    Predrag Sikiric
    Department of Pharmacology and Pathology Medical Faculty University of Zagreb, Zagreb, Croatia
    Curr Pharm Des 17:1612-32. 2011
  9. ncbi request reprint Stable gastric pentadecapeptide BPC 157 in trials for inflammatory bowel disease (PL-10, PLD-116, PL 14736, Pliva, Croatia). Full and distended stomach, and vascular response
    P Sikiric
    Department of Pharmacology, Medical Faculty University of Zagreb, Zagreb, Croatia
    Inflammopharmacology 14:214-21. 2006
  10. ncbi request reprint Anxiolytic effect of BPC-157, a gastric pentadecapeptide: shock probe/burying test and light/dark test
    P Sikiric
    Department of Pharmacology, Medical Faculty University of Zagreb, Salata 11, 10000 Zagreb, Croatia
    Acta Pharmacol Sin 22:225-30. 2001

Collaborators

  • A Krivic
  • Z Grabarevic
  • N Zarkovic
  • Ingrid Prkacin
  • T Novinscak
  • Ivan Zoricic
  • Sven Seiwerth
  • Luka Brcic
  • Bozo Radic
  • S Seiwerth
  • Alenka Boban Blagaic
  • Tomislav Anic
  • L Brcic
  • Mario Staresinic
  • Marko Sever
  • R Klicek
  • Robert Klicek
  • Lovorka Batelja
  • B Radic
  • Danijela Kolenc
  • A Boban Blagaic
  • Lidija Berkopic
  • G Aralica
  • T Anic
  • Tihomir Vuksic
  • M Sever
  • D Kolenc
  • Neven Kokic
  • Stjepan Mise
  • S Ilic
  • R Rucman
  • Domagoj Drmic
  • Spomenko Ilic
  • Miroslav Gjurasin
  • Ante Tonkic
  • M Staresinic
  • D Perovic
  • Igor Petrovic
  • D Drmic
  • Z Romic
  • I Brcic
  • Iva Brcic
  • Marijana Coric
  • Mihovil Ivica
  • Ivan Barisic
  • Hrvoje Vrcic
  • D Stancic-Rokotov
  • M Petek
  • Sandro Mise
  • Ivan Dobric
  • Alenka Boban-Blagaic
  • Petar Drvis
  • Vladimir Blagaic
  • B Turkovic
  • I Petrovic
  • Darko Perovic
  • Tomislav Cerovecki
  • Kamelija Zarkovic
  • Danira Pevec
  • Ivan Bojanic
  • Mario Tudor
  • Z Zoricic
  • M Hrelec
  • Dijana Balenovic
  • Sandra Skorjanec
  • Martina Lovric Bencic
  • N Jelovac
  • Ivan Kocman
  • Ivana Jukic
  • L Patrlj
  • Vedran Cesarec
  • Gojko Buljat
  • A Boban-Blagaic
  • Ivan Jelic
  • G Buljat
  • D Mikus
  • Ana Jakir
  • Drazen Shejbal
  • S Mise
  • Rudolf Rucman
  • Marijan Petek
  • Goran Dodig
  • Z Slobodnjak
  • Nikola Jelovac
  • Branko Turkovic
  • Zeljko Romic
  • M Bilic
  • D Stancic Rokotov
  • Martina Lovric-Bencic
  • L Batelja

Detail Information

Publications50

  1. ncbi request reprint Revised Robert's cytoprotection and adaptive cytoprotection and stable gastric pentadecapeptide BPC 157. Possible significance and implications for novel mediator
    Predrag Sikiric
    Department of Pharmacology, Medical Faculty University of Zagreb, Salata 11, POB 916, 10000 Zagreb, Croatia
    Curr Pharm Des 16:1224-34. 2010
    ....
  2. ncbi request reprint Stable Gastric Pentadecapeptide BPC 157-NO-system Relation
    Predrag Sikiric
    Department of Pharmacology, Medical Faculty University of Zagreb, Salata 11, POB 916, 10000 Zagreb, Croatia
    Curr Pharm Des 20:1126-35. 2014
    ..However, how this advantage of modulating NO-system (i. e., particular effect on eNOS gene), may be practically translated into an enhanced clinical performance remains to be determined. ..
  3. ncbi request reprint Stable gastric pentadecapeptide BPC 157 heals cysteamine-colitis and colon-colon-anastomosis and counteracts cuprizone brain injuries and motor disability
    R Klicek
    Department of Pharmacology, Medical Faculty, University of Zagreb, Zagreb, Croatia
    J Physiol Pharmacol 64:597-612. 2013
    ..Consistently, BPC 157 counteracted cerebellar ataxia and impaired forelimb function. Thereby, this experimental evidence advocates BPC 157 in both inflammatory bowel disease and multiple sclerosis therapy. ..
  4. ncbi request reprint Toxicity by NSAIDs. Counteraction by stable gastric pentadecapeptide BPC 157
    Predrag Sikiric
    Department of Pharmacology and Pathology, Medical Faculty University of Zagreb, Salata 11, POB 916, 10000 Zagreb, Croatia
    Curr Pharm Des 19:76-83. 2013
    ....
  5. ncbi request reprint Focus on ulcerative colitis: stable gastric pentadecapeptide BPC 157
    P Sikiric
    Department of Pharmacology, Medical Faculty University of Zagreb, Salata 11, POB 916, 10000 Zagreb, Croatia
    Curr Med Chem 19:126-32. 2012
    ..e., no toxic effect, limit test negative, LD1 not achieved, no side effect in trials) may counteract the problems commonly exercised in the use of peptidergic agents, particularly those used on a long-term basis...
  6. ncbi request reprint Pentadecapeptide BPC 157 attenuates chronic amphetamine-induced behavior disturbances
    Predrag Sikiric
    Department of Pharmacology, Medical Faculty University of Zagreb, Salata 11, POB 916, 10000 Zagreb, Croatia
    Acta Pharmacol Sin 23:412-22. 2002
    ....
  7. ncbi request reprint Corticosteroid-impairment of healing and gastric pentadecapeptide BPC-157 creams in burned mice
    P Sikiric
    Department of Pharmacology Medical Faculty, University of Zagreb, Salta 11, PO Box 916, Zagreb 10000, Croatia
    Burns 29:323-34. 2003
    ....
  8. ncbi request reprint Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract
    Predrag Sikiric
    Department of Pharmacology and Pathology Medical Faculty University of Zagreb, Zagreb, Croatia
    Curr Pharm Des 17:1612-32. 2011
    ..Thus, BPC 157 may improve gastrointestinal tract therapy...
  9. ncbi request reprint Stable gastric pentadecapeptide BPC 157 in trials for inflammatory bowel disease (PL-10, PLD-116, PL 14736, Pliva, Croatia). Full and distended stomach, and vascular response
    P Sikiric
    Department of Pharmacology, Medical Faculty University of Zagreb, Zagreb, Croatia
    Inflammopharmacology 14:214-21. 2006
    ..All these could be suggestive for its role as a natural protectant in gastric juice with particular function throughout stomach distension...
  10. ncbi request reprint Anxiolytic effect of BPC-157, a gastric pentadecapeptide: shock probe/burying test and light/dark test
    P Sikiric
    Department of Pharmacology, Medical Faculty University of Zagreb, Salata 11, 10000 Zagreb, Croatia
    Acta Pharmacol Sin 22:225-30. 2001
    ..To study anxiolytic effect of a gastric pentadecapeptide, BPC-157...
  11. ncbi request reprint Cysteamine-colon and cysteamine-duodenum lesions in rats. Attenuation by gastric pentadecapeptide BPC 157, cimetidine, ranitidine, atropine, omeprazole, sulphasalazine and methylprednisolone
    P Sikiric
    Department of Pharmacology, Medical Faculty, University of Zagreb, Salata 11, POB 916 Zagreb, Croatia
    J Physiol Paris 95:261-70. 2001
    ....
  12. ncbi request reprint Therapy effect of antiulcer agents on new chronic cysteamine colon lesion in rat
    P Sikiric
    Department of Pharmacology, Medical Faculty University of Zagreb, Salata 11, PO Box 916, Zagreb, Croatia
    J Physiol Paris 95:283-8. 2001
    ....
  13. ncbi request reprint New model of cytoprotection/adaptive cytoprotection in rats: endogenous small irritants, antiulcer agents and indomethacin
    P Sikiric
    Center for Digestive Diseases, Medical and Veterinary Faculty, University of Zagreb, Croatia
    Eur J Pharmacol 364:23-31. 1999
    ....
  14. ncbi request reprint Haloperidol-stomach lesions attenuation by pentadecapeptide BPC 157, omeprazole, bromocriptine, but not atropine, lansoprazole, pantoprazole, ranitidine, cimetidine and misoprostol in mice
    I Bilic
    Medical Faculty University of Zagreb, Croatia
    Life Sci 68:1905-12. 2001
    ..iii) Prostaglandins synthesis blockade effect: in haloperidol+indomethacin mice, previously effective agents, bromocriptine or omeprazole were not active, while BPC 157 effect was only lessened...
  15. ncbi request reprint Lung lesions and anti-ulcer agents beneficial effect: anti-ulcer agents pentadecapeptide BPC 157, ranitidine, omeprazole and atropine ameliorate lung lesion in rats
    D Stancic-Rokotov
    Clinic for Thoracic Surgery Jordanovac, Medical Faculty University of Zagreb, Zagreb, Croatia
    J Physiol Paris 95:303-8. 2001
    ....
  16. ncbi request reprint Chronic cytoprotection: pentadecapeptide BPC 157, ranitidine and propranolol prevent, attenuate and reverse the gastric lesions appearance in chronic alcohol drinking rats
    I Prkacin
    Department of Pharmacology, Medical Faculty University of Zagreb, Salata 11, PO Box 916, Zagreb, Croatia
    J Physiol Paris 95:295-301. 2001
    ....
  17. ncbi request reprint Portal hypertension and liver lesions in chronically alcohol drinking rats prevented and reversed by stable gastric pentadecapeptide BPC 157 (PL-10, PLD-116), and propranolol, but not ranitidine
    I Prkacin
    Department of Pharmacology, Medical Faculty University of Zagreb, Salata 11, PO Box 916, 10000, Zagreb, Croatia
    J Physiol Paris 95:315-24. 2001
    ..In summary, despite continuous chronic alcohol drinking, pentadecapeptide BPC 157, and propranolol may prevent portal hypertension as well as reverse already established portal hypertension along with related liver disturbances...
  18. ncbi request reprint The effect of a novel pentadecapeptide BPC 157 on development of tolerance and physical dependence following repeated administration of diazepam
    N Jelovac
    Department of Pharmacology, Medical Faculty University of Zagreb, Croatia
    Chin J Physiol 42:171-9. 1999
    ....
  19. ncbi request reprint Pentadecapeptide BPC 157 cream improves burn-wound healing and attenuates burn-gastric lesions in mice
    D Mikus
    Department of Pharmacology, Medical Faculty, University of Zagreb, Salata 11, P.O. Box 916, 10000, Zagreb, Croatia
    Burns 27:817-27. 2001
    ..This stable gastric pentadecapeptide appears to be active and gives a stimulation to burn healing at the defect site. The agent may act by causing an upregulation of the growth factors, as well as influencing other local factors...
  20. ncbi request reprint Over-dose insulin and stable gastric pentadecapeptide BPC 157. Attenuated gastric ulcers, seizures, brain lesions, hepatomegaly, fatty liver, breakdown of liver glycogen, profound hypoglycemia and calcification in rats
    S Ilic
    Department of Pharmacology and Pathology Medical Faculty University of Zagreb, Zagreb, Croatia
    J Physiol Pharmacol 60:107-14. 2009
    ..In conclusion, the success of BPC 157 therapy may indicate a likely role of BPC 157 in insulin controlling and BPC 157 may influence one or more causative process(es) after excessive insulin application...
  21. ncbi request reprint Abdominal aorta anastomosis in rats and stable gastric pentadecapeptide BPC 157, prophylaxis and therapy
    M Hrelec
    Department of Pharmacology and Pathology, Medical Faculty, University of Zagreb, Zagreb, Croatia
    J Physiol Pharmacol 60:161-5. 2009
    ....
  22. ncbi request reprint Modulatory effect of gastric pentadecapeptide BPC 157 on angiogenesis in muscle and tendon healing
    L Brcic
    Institute of Pathology, University of Zagreb Medical School, Zagreb, Croatia
    J Physiol Pharmacol 60:191-6. 2009
    ..Therefore the angiogenic potential of BPC 157 seems to be closely related to the healing process in vivo with BPC 157 stimulating angiogenesis by up-regulating VEGF expression...
  23. ncbi request reprint High hepatotoxic dose of paracetamol produces generalized convulsions and brain damage in rats. A counteraction with the stable gastric pentadecapeptide BPC 157 (PL 14736)
    S Ilic
    Department of Pharmacology and Pathology, Medical Faculty University of Zagreb, Zagreb, Croatia
    J Physiol Pharmacol 61:241-50. 2010
    ....
  24. doi request reprint Modulation of early functional recovery of Achilles tendon to bone unit after transection by BPC 157 and methylprednisolone
    A Krivic
    Department of Surgery, University Hospital Center Zagreb, Kispaticeva 12, Zagreb, 10000, Croatia
    Inflamm Res 57:205-10. 2008
    ..In the presented study we compared the effect of stable peptide BPC 157 and methylprednisolone on early functional recovery after Achilles tendon to bone transection in a rat model before collagen healing started...
  25. ncbi request reprint Gastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon and in vitro stimulates tendocytes growth
    M Staresinic
    Department of Pharmacology, Medical Faculty, University of Zagreb, Salata 11, Post Box 916, 10000 Zagreb, Croatia
    J Orthop Res 21:976-83. 2003
    ..In conclusion, these findings, particularly, Achilles tendon transection fully recovered in rats, peptide stability suitable delivery, usefully favor gastric pentadecapeptide BPC 157 in future Achilles tendon therapy...
  26. ncbi request reprint Gastric pentadecapeptide BPC 157 counteracts morphine-induced analgesia in mice
    A Boban Blagaic
    Department of Pharmacology and Pathology Medical Faculty University of Zagreb, Zagreb, Croatia
    J Physiol Pharmacol 60:177-81. 2009
    ....
  27. ncbi request reprint Ethanol gastric lesion aggravated by lung injury in rat. Therapy effect of antiulcer agents
    D Stancic-Rokotov
    Clinic for Thoracic Surgery Jordanovac, Medical Faculty University of Zagreb, Zagreb, Croatia
    J Physiol Paris 95:289-93. 2001
    ....
  28. ncbi request reprint BPC 157 therapy to detriment sphincters failure-esophagitis-pancreatitis in rat and acute pancreatitis patients low sphincters pressure
    I Petrovic
    Department of Pharmacology, Medical Faculty, University of Zagreb, Zagreb, Croatia
    J Physiol Pharmacol 62:527-34. 2011
    ..In acute pancreatitis patients lower pressure at rest was in both esophageal sphincters in acute pancreatitis patients. We conclude that BPC 157 could cure esophagitis/sphincter/acute pancreatitis healing failure...
  29. ncbi request reprint The stable gastric pentadecapeptide BPC 157, given locally, improves CO2 laser healing in mice
    M Bilic
    Department of Pharmacology, Medical Faculty, University of Zagreb, Salata 11, P O Box 916, 10000 Zagreb, Croatia
    Burns 31:310-5. 2005
    ..The effect was produced with a simple method of application and favourable peptide stability (no carrier), and confirms the effectiveness of an ointment containing 1 microg BPC 157 (dissolved in saline)/g neutral cream...
  30. ncbi request reprint Stable gastric pentadecapeptide BPC 157 in trials for inflammatory bowel disease (PL-10, PLD-116, PL14736, Pliva, Croatia) heals ileoileal anastomosis in the rat
    Tihomir Vuksic
    Department of Pharmacology, Medical Faculty, University of Zagreb, Salata 11, POB 916, 10000 Zagreb, Croatia
    Surg Today 37:768-77. 2007
    ..e., perorally, parenterally). We studied the effectiveness of BPC 157 for ileoileal anastomosis healing in rats...
  31. doi request reprint Therapy for unhealed gastrocutaneous fistulas in rats as a model for analogous healing of persistent skin wounds and persistent gastric ulcers: stable gastric pentadecapeptide BPC 157, atropine, ranitidine, and omeprazole
    Sandra Skorjanec
    Department of Pharmacology, Medical School, University of Zagreb, Salata 11, 10000, Zagreb, Croatia
    Dig Dis Sci 54:46-56. 2009
    ..Therefore, with the fistulas therapy, we challenge the wound/growth factors theory of the analogous nonhealing of wounds and persistent gastric ulcers...
  32. ncbi request reprint Pentadecapeptide BPC 157, in clinical trials as a therapy for inflammatory bowel disease (PL14736), is effective in the healing of colocutaneous fistulas in rats: role of the nitric oxide-system
    Robert Klicek
    Department of Pharmacology, Medical School, University of Zagreb, Croatia
    J Pharmacol Sci 108:7-17. 2008
    ..Sulphasalazine was only moderately effective, and corticosteroid even had an aggravating effect...
  33. doi request reprint Peptide therapy with pentadecapeptide BPC 157 in traumatic nerve injury
    Miroslav Gjurasin
    Department of Pharmacology, Medical Faculty, University of Zagreb Medical School, Salata 11, POB 916, 10000 Zagreb, Croatia
    Regul Pept 160:33-41. 2010
    ..Thus, BPC 157 markedly improved rat sciatic nerve healing...
  34. doi request reprint Gastric pentadecapeptide BPC 157 and short bowel syndrome in rats
    Marko Sever
    Department of Pharmacology, Medical School, University of Zagreb, Salata 11, 10000, Zagreb, Croatia
    Dig Dis Sci 54:2070-83. 2009
    ..In conclusion, pentadecapeptide BPC 157 could be helpful to cure short bowel syndrome...
  35. doi request reprint Gastric pentadecapeptide BPC 157 as an effective therapy for muscle crush injury in the rat
    Tomislav Novinscak
    Department of Pharmacology, Institute of Pathology, University of Zagreb Medical School, Salata 11, 10 000, Zagreb, Croatia
    Surg Today 38:716-25. 2008
    ..BPC 157 is effective without a carrier, and it is presently undergoing trials for inflammatory bowel disease, and no toxicity has so far been reported...
  36. ncbi request reprint Achilles detachment in rat and stable gastric pentadecapeptide BPC 157: Promoted tendon-to-bone healing and opposed corticosteroid aggravation
    Andrija Krivic
    Laboratory for Experimental Surgery, Department of Pharmacology, University of Zagreb Medical School, Salata 11, Zagreb 10000, Croatia
    J Orthop Res 24:982-9. 2006
    ..Thus, direct tendon-to-bone healing using stabile nontoxic peptide BPC 157 without a carrier might successfully exchange the present reconstructive surgical methods...
  37. ncbi request reprint Different effect of antiulcer agents on rat cysteamine-induced duodenal ulcer after sialoadenectomy, but not gastrectomy
    Vlado Bedekovic
    Department of Pharmacology, Medical Faculty University of Zagreb, Salata 11, POB916, 10000 Zagreb, Croatia
    Eur J Pharmacol 477:73-80. 2003
    ....
  38. ncbi request reprint Effective therapy of transected quadriceps muscle in rat: Gastric pentadecapeptide BPC 157
    Mario Staresinic
    Department of Pharmacology, School of Medicine, University of Zagreb, Salata 11, P O B 916, 10000 Zagreb, Croatia
    J Orthop Res 24:1109-17. 2006
    ..Thus, posttransection healing-consistently improved-may suggest this peptide therapeutic application in muscle disorders...
  39. doi request reprint Pentadecapeptide BPC 157 (PL 14736) improves ligament healing in the rat
    Tomislav Cerovecki
    University Hospital of Traumatology, Zagreb, Croatia
    J Orthop Res 28:1155-61. 2010
    ..Commonly, BPC 157 microg-ng-rats exhibited consistent functional, biomechanical, macroscopic and histological healing improvements. Thus, we suggest BPC 157 improved healing of acute ligament injuries in further ligament therapy...
  40. doi request reprint Inhibition of methyldigoxin-induced arrhythmias by pentadecapeptide BPC 157: a relation with NO-system
    Dijana Balenovic
    Department of Pharmacology, University of Zagreb Medical School, Salata 11, 10000 Zagreb, Croatia
    Regul Pept 156:83-9. 2009
    ..In conclusion, digitalis-induced arrhythmias in rats could be prevented and counteracted by pentadecapeptide BPC 157, mainly through an interaction with the NO-system...
  41. ncbi request reprint An experimental model of prolonged esophagitis with sphincter failure in the rat and the therapeutic potential of gastric pentadecapeptide BPC 157
    Igor Petrovic
    Department of Pharmacology, Medical Faculty, University of Zagreb, Zagreb, Croatia
    J Pharmacol Sci 102:269-77. 2006
    ..Ranitidine, given as the standard drug using the same protocol (50 mg/kg, i.p., once daily; 0.83 mg/ml in drinking water; or 50 mg/kg directly into the stomach) had no effect...
  42. ncbi request reprint Impact of pentadecapeptide BPC 157 on muscle healing impaired by systemic corticosteroid application
    Danira Pevec
    Department of Pharmacology, University of Zagreb Medical School, Zagreb, Croatia
    Med Sci Monit 16:BR81-88. 2010
    ..Importantly, it counteracted corticosteroid-impairment in tendon to bone healing. Thus BPC 157 is proposed as an effective treatment that can improve muscle healing in spite of corticosteroid treatment...
  43. ncbi request reprint Prolonged esophagitis after primary dysfunction of the pyloric sphincter in the rat and therapeutic potential of the gastric pentadecapeptide BPC 157
    Ivan Dobric
    Department of Pharmacology, Medical School, University of Zagreb, Croatia
    J Pharmacol Sci 104:7-18. 2007
    ..Ranitidine, given using the same protocol (50 mg/kg, intraperitoneally, once daily; 0.83 mg/ml in drinking water; 50 mg/kg directly into the stomach) does not have an effect in either rats with esophagitis or in normal rats...
  44. ncbi request reprint Gastric pentadecapeptide BPC 157 effective against serotonin syndrome in rats
    Alenka Boban Blagaic
    Department of Pharmacology, Medical Faculty, University of Zagreb, Salata 11, POB 916, 10000 Zagreb, Croatia
    Eur J Pharmacol 512:173-9. 2005
    ....
  45. ncbi request reprint The influence of gastric pentadecapeptide BPC 157 on acute and chronic ethanol administration in mice. The effect of N(G)-nitro-L-arginine methyl ester and L-arginine
    Alenka Boban-Blagaic
    Department of Pharmacology, School of Medicine, University of Zagreb, Salata 11, POB 916, 10000 Zagreb, Croatia
    Med Sci Monit 12:BR36-45. 2006
    ..e. L-NAME) were challenged with stable gastric pentadecapeptide BPC 157, which inhibits both acute alcohol intoxication and alcohol withdrawal symptoms...
  46. doi request reprint Traumatic brain injury in mice and pentadecapeptide BPC 157 effect
    Mario Tudor
    Department of Pharmacology, Medical Faculty University of Zagreb, 10000 Zagreb, Croatia
    Regul Pept 160:26-32. 2010
    ..093 Ns-TBI. For a more severe force impulse (0.130 Ns, 0.145 Ns, or 0159 Ns), the time-relation to improve the conscious/unconscious/death ratio was: 5 min (0.130 Ns-TBI), 20 min (0.145 Ns-TBI) or 30 min (0.159 Ns-TBI)...
  47. ncbi request reprint Doxorubicine-congestive heart failure-increased big endothelin-1 plasma concentration: reversal by amlodipine, losartan, and gastric pentadecapeptide BPC157 in rat and mouse
    Martina Lovric-Bencic
    Department of Pharmacology, Medical Faculty, University of Zagreb, Croatia
    J Pharmacol Sci 95:19-26. 2004
    ..Losartan reduces AST, ALT, CK, and LDH serum values. BPC157 (10 ng/kg) reduces AST and ALT serum values. Clinical status of CHF-rats and -mice is accordingly improved by the BPC157 regimens and amlodipine...
  48. ncbi request reprint The influence of gastric pentadecapeptide BPC 157 on acute and chronic ethanol administration in mice
    Alenka Boban Blagaic
    Department of Pharmacology Medical Faculty University of Zagreb, Salata 11, P O Box 916, 10000 Zagreb, Croatia
    Eur J Pharmacol 499:285-90. 2004
    ..6 g/kg) through 13 days, with provocation on the 14th day...
  49. ncbi request reprint The presentation and organization of adaptive cytoprotection in the rat stomach, duodenum, and colon. Dedicated to André Robert the founder of the concept of cytoprotection and adaptive cytoprotection
    Stjepan Mise
    Department of Pharmacology, Medical Faculty University of Zagreb, Zagreb, Croatia
    Med Sci Monit 12:BR146-53. 2006
    ..e. one hour) defined by Robert in the stomach only...
  50. ncbi request reprint Comment on "Use of recombinant human bone morphogenetic protein-2 to enhance tendon healing in a bone tunnel"
    Andrija Krivic
    Am J Sports Med 31:636-7; author reply 637-8. 2003