Research Topics
Genomes and GenesSpecies | Nela PivacSummaryCountry: Croatia Publications
| Collaborators
|
Detail Information
Publications
The association between brain-derived neurotrophic factor Val66Met variants and psychotic symptoms in posttraumatic stress disorderNela Pivac
Laboratory for Molecular Neuropsychiatry, Division of Molecular Medicine, Rudjer Boskovic Institute, Zagreb, Croatia
World J Biol Psychiatry 13:306-11. 2012..This study intended to assess whether the Met allele is overrepresented in unrelated Caucasian male veterans with psychotic PTSD compared to veteran controls...
Monoamine oxidase (MAO) intron 13 polymorphism and platelet MAO-B activity in combat-related posttraumatic stress disorderNela Pivac
Rudjer Boskovic Institute, Division of Molecular Medicine, PO Box 180, HR 10002 Zagreb, Croatia
J Affect Disord 103:131-8. 2007..Platelet monoamine oxidase (MAO-B) has been associated with susceptibility to various psychiatric disorders, personality traits and behaviors...
The lack of genotype-phenotype relationship between platelet serotonin concentration and serotonin transporter gene promoter polymorphism in healthy subjectsNela Pivac
Division of Molecular Medicine, Rudjer Boskovic Institute, POBox 180, HR 10002 Zagreb, Croatia
Neurosci Lett 462:45-8. 2009....
Ethnic differences in brain-derived neurotrophic factor Val66Met polymorphism in Croatian and Korean healthy participantsNela Pivac
Laboratory for Molecular Neuropsychiatry, Division of Molecular Medicine, Rudjer Boskovic Institute, 10002 Zagreb, Croatia
Croat Med J 50:43-8. 2009....
Brain derived neurotrophic factor Val66Met polymorphism and psychotic symptoms in Alzheimer's diseaseNela Pivac
Division of Molecular Medicine, Rudjer Boskovic Institute, Croatia
Prog Neuropsychopharmacol Biol Psychiatry 35:356-62. 2011..The aim of the study was to evaluate the association between BDNF Val66Met variants and AD, as well as onset of AD or presence of psychotic symptoms in AD...
COLLEGIUM INTERNATIONALE NEURO-PSYCHOPHARMACOLOGICUM (C.I.N.P.) 24th CONGRESS (Paris, France, 20-24 June 2004)Nela Pivac
Rudjer Boskovic Institute, POBox 180, HR 10002 Zagreb, Croatia
Psychiatr Danub 16:171-7. 2004..The sponsorship by the pharmaceutical industries was visible only in the selected sponsored symposia...
The lack of association between monoamine oxidase (MAO) intron 13 polymorphism and platelet MAO-B activity among menNela Pivac
Division of Molecular Medicine, Rudjer Boskovic Institute, PO Box 180, HR 10002 Zagreb, Croatia
Life Sci 79:45-9. 2006....
Platelet serotonin in combat related posttraumatic stress disorder with psychotic symptomsNela Pivac
Ruder Boskovic Institute, PO Box 180, HR 10002 Zagreb, Croatia
J Affect Disord 93:223-7. 2006..Platelet serotonin (5-hydroxytryptamine, 5-HT) was used as a peripheral 5-HT marker to identify particular symptoms in PTSD...
Pharmacotherapy of treatment-resistant combat-related posttraumatic stress disorder with psychotic featuresNela Pivac
Division of Molecular Medicine, Rudjer Boskovic Institute, Zagreb, Croatia
Croat Med J 47:440-51. 2006....
Federation of European Pharmacological Societies-fourth annual meeting. Part I. 14-17 July 2004, Porto, PortugalNela Pivac
Rudjer Boskovic Institute, PO Box 1016, Bijenicka 54, HR-10000, Zagreb, Croatia
IDrugs 7:829-32. 2004
Risperidone in psychotic combat-related posttraumatic stress disorder: an open trialDragica Kozaric-Kovacic
National Centre for Psychotrauma, Department of Psychiatry, Dubrava University Hospital, Zagreb, Croatia
J Clin Psychiatry 66:922-7. 2005..We hypothesized that war veterans with psychotic PTSD, resistant to prior antidepressant treatment, would respond well to 6 weeks of treatment with the atypical antipsychotic risperidone, given as a monotherapy...
Suicide attempt, smoking, comorbid depression, and platelet serotonin in alcohol dependenceKorona Nenadic-Sviglin
Center for Alcoholism and other Addictions, Psychiatric Hospital Vrapce, Zagreb, Croatia
Alcohol 45:209-16. 2011....
Platelet 5-HT concentration and comorbid depression in war veterans with and without posttraumatic stress disorderDorotea Muck-Seler
Laboratory for Molecular Neuropharmacology, Rudjer Boskovic Institute, P O Box 180, HR 10002, Zagreb, Croatia
J Affect Disord 75:171-9. 2003..The present study focused on platelet serotonin (5-HT) concentration and symptoms of comorbid depression in war veterans with or without PTSD...
Platelet serotonin concentration and monoamine oxidase type B activity in female patients in early, middle and late phase of Alzheimer's diseaseDorotea Muck-Seler
Division of Molecular Medicine, Ruder Boskovic Institute, HR 10000 Zagreb, Croatia
Prog Neuropsychopharmacol Biol Psychiatry 33:1226-31. 2009..Lower platelet 5-HT concentration and MAO-B activity in the late phase of AD suggested that these markers might indicate severity and/or clinical progress of AD...
Platelet serotonin and monoamine oxidase in Alzheimer's disease with psychotic featuresNinoslav Mimica
Department of Psychiatry, Psychiatric Hospital Vrapce, Zagreb, Croatia
Coll Antropol 32:119-22. 2008..Our data suggest that platelet MAO-B activity, but not platelet 5-HT concentration, could differentiate between psychotic and non-psychotic subtypes of AD...
Brain-derived neurotrophic factor Val66Met polymorphism and alcohol-related phenotypesGordana Nedic
Division of Molecular Medicine, Rudjer Boskovic Institute, Bijenicka 54, HR 10000 Zagreb, Croatia
Prog Neuropsychopharmacol Biol Psychiatry 40:193-8. 2013..In conclusion, these data do not support the view that BDNF Val66Met polymorphism correlates with the specific alcohol related phenotypes in ethnically homogenous medication-free Caucasian subjects with alcohol dependence...
Dopamine beta-hydroxylase (DBH) activity and -1021C/T polymorphism of DBH gene in combat-related post-traumatic stress disorderMaja Mustapic
Division of Molecular Medicine, Rudjer Boskovic Institute, Zagreb, Croatia
Am J Med Genet B Neuropsychiatr Genet 144:1087-9. 2007....
Association study of a functional catechol-O-methyltransferase (COMT) Val108/158Met polymorphism and suicide attempts in patients with alcohol dependenceGordana Nedic
Division of Molecular Medicine, Rudjer Boskovic Institute, Zagreb, Croatia
Int J Neuropsychopharmacol 14:377-88. 2011....
Alzheimer's disease and type 2 diabetes: the association study of polymorphisms in tumor necrosis factor-alpha and apolipoprotein E genesMaja Mustapic
Rudjer Boskovic Institute, Zagreb, Croatia
Metab Brain Dis 27:507-12. 2012..Our data confirm the association between the ApoE4 allele and AD, and point out the E2 allele of ApoE gene as the possible risk factor for T2D...
Association study of a functional catechol-O-methyltransferase polymorphism and smoking in healthy Caucasian subjectsGordana Nedic
Division of Molecular Medicine, Rudjer Boskovic Institute, Bijenicka 54, PO Box 180, HR 10002 Zagreb, Croatia
Neurosci Lett 473:216-9. 2010..These results suggest that carriers of the high activity COMT variant are more prone to develop a higher level of nicotine dependence, or that they release more dopamine than carriers of Met/Met or Met/Val genotypes...
The effect of lamotrigine on platelet monoamine oxidase type B activity in patients with bipolar depressionDorotea Muck-Seler
Division of Molecular Medicine, Rudjer Boskovic Institute, POBox 180, HR 10002 Zagreb, Croatia
Prog Neuropsychopharmacol Biol Psychiatry 32:1195-8. 2008..These findings provide in vivo insight of lamotrigine effect on platelet MAO-B activity in patients with bipolar depression. Its in vivo MAO-B inhibiting effect might have contributed in part to its antidepressant activity...
Platelet serotonin and plasma prolactin and cortisol in healthy, depressed and schizophrenic womenDorotea Muck-Seler
Laboratory for Molecular Neuropharmacology, Division of Molecular Medicine, Rudjer Boskovic Institute, P O Box 180, HR 10002 Zagreb, Croatia
Psychiatry Res 127:217-26. 2004..Our data, although obtained on peripheral biochemical markers, indicate that depression and schizophrenia are characterized by disturbed 5-HT transmission and dysregulated HPA axis activity...
Platelet serotonin concentration in alcoholic subjectsNela Pivac
Division of Molecular Medicine, Ruder Boskovic Institute, POBox 180, HR 10002 Zagreb, Croatia
Life Sci 76:521-31. 2004..Among male alcoholics the presence of comorbid PTSD partly normalized the decreased platelet 5-HT values. The results of the present study support the hypothesis that alterations in 5-HT system might be related to alcoholism...
Comorbid depression and platelet serotonin in hemodialysis patientsIvan Barisic
Department of Urology, Dialysis Center, University Hospital Center Zagreb, Zagreb, Croatia
Nephron Clin Pract 96:c10-4. 2004..Comorbid depression often occurs in chronic renal failure patients on hemodialysis (HD). Reduced serotonin (5-HT) function is implicated in the pathophysiology of depression...
Platelet serotonin concentration and suicidal behavior in combat related posttraumatic stress disorderZrnka Kovacic
Department of Psychopharmacology, Croatian Institute for Brain Research, School of Medicine, University of Zagreb, Psychiatric Hospital Vrapce, University Department of General and Forensic Psychiatry and Clinical Psychophysiology, Zagreb, Croatia
Prog Neuropsychopharmacol Biol Psychiatry 32:544-51. 2008....
Long-term sertraline treatment and peripheral biochemical markers in female depressed patientsNela Pivac
Laboratory for Molecular Neuropharmacology, Division of Molecular Medicine, , P.O. Box 180, HR-10002 Zagreb, Croatia
Prog Neuropsychopharmacol Biol Psychiatry 27:759-65. 2003....
Serum lipid levels in patients with Alzheimer's diseasePaola Presecki
Sveti Ivan Psychiatric Hospital, Jankomir, Zagreb, Croatia
Coll Antropol 35:115-20. 2011..Further studies are needed to confirm the relationship between lipid levels and cognition, and to validate the lipid profile as a biological marker for the progress of AD...
Platelet serotonergic markers in posttraumatic stress disorderNela Pivac
Laboratory for Molecular Neuropharmacology, Division of Molecular Medicine, , PO Box 180, Zagreb HR-10002, Croatia
Prog Neuropsychopharmacol Biol Psychiatry 26:1193-8. 2002....
Thyroid activity in patients with major depressionTamara Stipcevic
Department of Molecular Medicine, Institute Ruder Boskovic, Zagreb, Croatia
Coll Antropol 32:973-6. 2008..Future research should identify different behavioral endophenotypes characteristic for depression, which would greatly facilitate delineating the biological phenomena associated with this psychiatric illness...
Association study of a functional catechol-o-methyltransferase polymorphism and cognitive function in patients with dementiaGordana Nedic
Rudjer Boskovic Institute, Division of Molecular Medicine, Zagreb, Croatia
Coll Antropol 35:79-84. 2011..Further study on larger sample of patients is needed to clarify the role of COMT polymorphism in cognitive functions...
Quetiapine augmentation in treatment-resistant depression: a naturalistic studyMarina Sagud
Department of Psychiatry, Clinical Hospital Centre Zagreb, , Zagreb, Croatia
Psychopharmacology (Berl) 187:511-4. 2006..CONCLUSION: Our preliminary data indicate that quetiapine add-on therapy appears to have beneficial effects in the treatment of patients with TRD...
Quetiapine treatment in an open trial in combat-related post-traumatic stress disorder with psychotic featuresDragica Kozaric Kovacic
University Hospital Dubrava, Department of Psychiatry, Referral Centre for the Stress related Disorders of the Ministry of Health and Social Welfare, Regional Centre for Psychotrauma, Zagreb, Croatia
Int J Neuropsychopharmacol 10:253-61. 2007..Our present and previous data suggest that treatment-resistant psychotic PTSD patients may improve after taking atypical antipsychotics...
The effects of paroxetine and tianeptine on peripheral biochemical markers in major depressionDorotea Muck-Seler
Ruder Boskovic Institute, Division of Molecular Medicine, PO Box 180, HR 10002 Zagreb, Croatia
Prog Neuropsychopharmacol Biol Psychiatry 26:1235-43. 2002..The results suggest that pretreatment platelet 5-HT levels, but not other peripheral biochemical markers, might predict therapeutic outcome at least in paroxetine-treated patients...
Platelet monoamine oxidase activity in children with attention-deficit/hyperactivity disorderGordana Nedic
Division of Molecular Medicine, Rudjer Boskovic Institute, Zagreb, Croatia
Psychiatry Res 175:252-5. 2010..In line with hypotheses of lower platelet MAO activity in different types of psychopathology, children with different subtypes of ADHD had significantly lower platelet MAO-B activity than control children...
Olanzapine versus fluphenazine in an open trial in patients with psychotic combat-related post-traumatic stress disorderNela Pivac
Division of Molecular Medicine, Rudjer Boskovic Institute, PO Box 180, 10002 Zagreb, Croatia
Psychopharmacology (Berl) 175:451-6. 2004..Combat-related post-traumatic stress disorder (PTSD) is often complicated with other psychiatric comorbidities, and is refractory to treatment...
Platelet serotonin concentration and monoamine oxidase activity in hypothyroid patientsTamara Stipcevic
Division of Molecular Medicine, Rudjer Boskovic Institute, Zagreb, Croatia
Horm Res 71:207-12. 2009..The aim of the study was to determine platelet biochemical markers (5-HT concentration and monoamine oxidase B, MAO-B, activity) in hypothyroid patients...
Platelet serotonin concentration in children with attention-deficit/hyperactivity disorderVesna Hercigonja Novkovic
Polyclinic Kocijan Hercigonja, Zagreb, Croatia
Neuropsychobiology 59:17-22. 2009..Peripheral indices of central 5-HT function were shown in recent studies to be lower, unaltered, or increased in ADHD...
Prostate cancer in elderly Croatian men: 5-HT genetic polymorphisms and the influence of androgen deprivation therapy on osteopenia--a pilot studyDaria Pasalic
Department of Chemistry, Biochemistry, and Clinical Chemistry, School of Medicine, University of Zagreb, Zagreb, Croatia
Genet Test Mol Biomarkers 16:598-604. 2012..The aim of this study was to determine the relationship between body mass index, biochemical parameters, and 5-hydroxytryptamine (5-HT) genetic polymorphisms and prostate dysfunction in an elderly general male population...
Effects of sertraline treatment on plasma cortisol, prolactin and thyroid hormones in female depressed patientsMarina Sagud
University Hospital Center Zagreb, Department of Psychiatry, Zagreb, Croatia
Neuropsychobiology 45:139-43. 2002..The data show different and time-dependent effects of sertraline treatment on plasma cortisol, PRL and thyroid hormones in female depressed patients...
Gene expression in visceral and subcutaneous adipose tissue in overweight womenMirko Korsic
Department of Endocrinology and Metabolic Disorders, University Hospital Center Zagreb, Zagreb, Croatia
Front Biosci (Elite Ed) 4:2834-44. 2012..The data from this preliminary study suggest enrichment of inflammation and oxidative stress related pathways in VAT, while insulin homeostasis pathways as well as pathways pertaining to several growth factors are enriched in SAT...
Are there differences in serum cholesterol and cortisol concentrations between violent and non-violent schizophrenic male suicide attempters?Darko Marcinko
Department of Psychiatry, Clinical Hospital Center Zagreb, Zagreb, Croatia
Coll Antropol 29:153-7. 2005..The hypothesis of an association of violent suicidal attempts and peripheral biological markers (cholesterol and cortisol) was supported by our findings...
Serum cholesterol concentration and structured individual psychoanalytic psychotherapy in suicidal and non-suicidal male patients suffering from borderline personality disorderDarko Marcinko
University of Zagreb, Zagreb University Hospital Center, Department of Psychiatry, Zagreb, Croatia
Coll Antropol 35:219-23. 2011..These results emphasized the role of this type of psychotherapy in preventing suicidal behavior in BPD patients...
Changes in plasma and IgG N-glycome during childhood and adolescenceMaja Pucic
Genos Ltd, Glycobiology Laboratory, Zagreb, Croatia
Glycobiology 22:975-82. 2012..These important observations should be accounted for when glycan-based diagnostic tests or therapeutics are being developed or evaluated...
Acute immunomodulatory effects of iron polyisomaltosate in ratsMarija Poljak-Blazi
Division of Molecular Medicine, Laboratory for Oxidative Stress, Rudjer Boskovic Institute, Zagreb, Croatia
Immunobiology 214:121-8. 2009..Iron polyisomaltosate presumably activated reactive oxygen species resulting in the stimulation of the acute phase reactants in the liver...
The involvement of noradrenergic mechanisms in the suppressive effects of diazepam on the hypothalamic-pituitary-adrenal axis activity in female ratsDubravka Svob Strac
Division of Molecular Medicine, Ruđer Bošković Institute, Zagreb, Croatia
Croat Med J 53:214-23. 2012..To elucidate the involvement of noradrenergic system in the mechanism by which diazepam suppresses basal hypothalamic-pituitary-adrenal (HPA) axis activity...
Pharmacology--Fourth Croatian Congress. 15-18 September 2004, Split, CroatiaNela Pivac
Rudjer Boskovic Institute, PO Box 1016, Bijenicka 54, HR-10000, Zagreb, Croatia
IDrugs 7:1000-4. 2004
Human plasma glycome in attention-deficit hyperactivity disorder and autism spectrum disordersNela Pivac
Division of Molecular Medicine, Ruđer Bošković Institute, Bijenicka cesta 54, 10000 Zagreb, Croatia
Mol Cell Proteomics 10:M110.004200. 2011..The design of this study prevented any functional conclusions about the observed associations, but specific differences in glycosylation appears to be strongly associated with ADHD and warrants further studies in this direction...
The effect of natural clinoptilolite on the serotonergic receptors in the brain of mice with mammary carcinomaDorotea Muck-Seler
Ruder Boskovic Institute, Laboratory for Molecular Neuropharmacology, Division of Molecular Medicine, PO Box 180, HR 10002 Zagreb, Croatia
Life Sci 73:2059-69. 2003..The mechanism of the indirect action of MZ on the brain serotonergic receptors might be achieved by the alterations in the electrolytes balance, and/or by the regulation of the immune system...
Acute treatment with fluvoxamine elevates rat brain serotonin synthesis in some terminal regions: an autoradiographic studyDorotea Muck-Seler
Cone Neurosurgical Research Laboratory, Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, 3801 University Street, Montreal, Quebec, Canada
Nucl Med Biol 39:1053-7. 2012..A considerable body of evidence indicates the involvement of the neurotransmitter serotonin (5-HT) in the pathogenesis and treatment of depression...
The influence of daylight exposure on platelet 5-HT levels in patients with major depression and schizophreniaDulijano Ljubicic
Psychiatric Clinic, Clinical Hospital Centre Rijeka, Rijeka, Croatia
J Photochem Photobiol B 89:63-9. 2007....
The effect of lamotrigine on platelet serotonin concentration in patients with bipolar depressionMarina Sagud
Psychopharmacology (Berl) 197:683-5. 2008
Platelet serotonin and serum lipids in psychotic maniaMarina Sagud
University Hospital Center Zagreb, Department of Psychiatry, Kispaticeva 12, 10 000 Zagreb, Croatia
J Affect Disord 97:247-51. 2007....
Genetics of schizophrenia in the context of integrative psychiatryMarina Sagud
University Psychiatric Clinic Rebro, Clinical Hospital Centre Zagreb, Kispaticeva 12, 10000 Zagreb, Croatia
Psychiatr Danub 20:364-8. 2008....
Platelet monoamine oxidase in alcoholismNela Pivac
Psychopharmacology (Berl) 182:194-6. 2005
Platelet serotonin and serum cholesterol concentrations in suicidal and non-suicidal male patients with a first episode of psychosisDarko Marcinko
Department of Psychiatry, Clinical Hospital Center Zagreb, Kispaticeva 12, 10000 Zagreb, Croatia
Psychiatry Res 150:105-8. 2007..Our results suggest that lower concentrations of serum cholesterol and platelet 5-HT in patients with a first episode of psychosis might be useful biological markers of suicidality...
Effects of desipramine on regional serotonin synthesis in the rat brain: acute and chronic autoradiographic studiesNela Pivac
Cone Neurosurgical Research Laboratory, Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, 3801 University St, Montreal, Que, Canada H3A 2B4
Neurochem Int 43:611-9. 2003..This suggests that the effect of desipramine on 5-HT synthesis rate is time-dependent and differs in the cell bodies and structures containing 5-HT nerve terminals...
