K Pavelic

Summary

Country: Croatia

Publications

  1. ncbi request reprint Natural zeolite clinoptilolite: new adjuvant in anticancer therapy
    K Pavelic
    Ruder Boskovic Institute, Division of Molecular Medicine, Zagreb, Croatia
    J Mol Med (Berl) 78:708-20. 2001
  2. pmc Aberration of FHIT gene is associated with increased tumor proliferation and decreased apoptosis-clinical evidence in lung and head and neck carcinomas
    K Pavelic
    Ruder Boskovic Institute, Division of Molecular Medicine, Zagreb, Croatia
    Mol Med 7:442-53. 2001
  3. ncbi request reprint Immunostimulatory effect of natural clinoptilolite as a possible mechanism of its antimetastatic ability
    K Pavelic
    Rudjer Boskovic Institute, Division of Molecular Medicine, Bijenicka 54, HR 10000 Zagreb, Croatia
    J Cancer Res Clin Oncol 128:37-44. 2002
  4. pmc The role of insulin-like growth factor 2 and its receptors in human tumors
    Kresimir Pavelic
    Division of Molecular Medicine, Rudjer Boskovic Institute, Zagreb, Croatia
    Mol Med 8:771-80. 2002
  5. ncbi request reprint Increased activity of nm23-H1 gene in squamous cell carcinoma of the head and neck is associated with advanced disease and poor prognosis
    K Pavelic
    Division of Molecular Medicine, Ruder Boskovic Institute, Zagreb, Croatia
    J Mol Med (Berl) 78:111-8. 2000
  6. ncbi request reprint The expression and role of insulin-like growth factor II in malignant hemangiopericytomas
    K Pavelic
    Division of Molecular Medicine, Ruder Boskovic Institute, Zagreb, Croatia
    J Mol Med (Berl) 77:865-9. 1999
  7. ncbi request reprint Collision tumour in the pelvic cavity: rectal leiomyosarcoma and prostate adenocarcinoma
    J Pavelic
    Division of Molecular Medicine, Ruder Boskovic Institute, Bijenicka 54, 10000 Zagreb, Croatia
    J Cancer Res Clin Oncol 126:95-100. 2000
  8. ncbi request reprint Recent advances in molecular genetics of breast cancer
    K Pavelic
    Ruder Boskovic Institute, Division of Molecular Medicine, Bijenicka 54, P O Box 180, 10002 Zagreb, Croatia
    J Mol Med (Berl) 79:566-73. 2001
  9. ncbi request reprint Molecular pathology of hemangiopericytomas accompanied by severe hypoglycemia: oncogenes, tumor-suppressor genes and the insulin-like growth factor family
    K Pavelic
    Division of Molecular Medicine Ruder Bosković Institute, Zagreb, Croatia
    J Cancer Res Clin Oncol 124:307-14. 1998
  10. ncbi request reprint Insulin-like growth factor family in malignant haemangiopericytomas: the expression and role of insulin-like growth factor I receptor
    K Pavelic
    Division of Molecular Medicine, Ruder Boskovic Institute, HR 10000 Zagreb, Croatia
    J Pathol 188:69-75. 1999

Collaborators

Detail Information

Publications31

  1. ncbi request reprint Natural zeolite clinoptilolite: new adjuvant in anticancer therapy
    K Pavelic
    Ruder Boskovic Institute, Division of Molecular Medicine, Zagreb, Croatia
    J Mol Med (Berl) 78:708-20. 2001
    ..These data indicate that clinoptilolite treatment might affect cancer growth by attenuating survival signals and inducing tumor suppressor genes in treated cells...
  2. pmc Aberration of FHIT gene is associated with increased tumor proliferation and decreased apoptosis-clinical evidence in lung and head and neck carcinomas
    K Pavelic
    Ruder Boskovic Institute, Division of Molecular Medicine, Zagreb, Croatia
    Mol Med 7:442-53. 2001
    ..Loss of FHIT function may be important in the development and/or progression of various types of cancer...
  3. ncbi request reprint Immunostimulatory effect of natural clinoptilolite as a possible mechanism of its antimetastatic ability
    K Pavelic
    Rudjer Boskovic Institute, Division of Molecular Medicine, Bijenicka 54, HR 10000 Zagreb, Croatia
    J Cancer Res Clin Oncol 128:37-44. 2002
    ..These properties make them interesting for pharmaceutical industry and medicine...
  4. pmc The role of insulin-like growth factor 2 and its receptors in human tumors
    Kresimir Pavelic
    Division of Molecular Medicine, Rudjer Boskovic Institute, Zagreb, Croatia
    Mol Med 8:771-80. 2002
    ....
  5. ncbi request reprint Increased activity of nm23-H1 gene in squamous cell carcinoma of the head and neck is associated with advanced disease and poor prognosis
    K Pavelic
    Division of Molecular Medicine, Ruder Boskovic Institute, Zagreb, Croatia
    J Mol Med (Berl) 78:111-8. 2000
    ..Together with results obtained on lung cancer, our observations suggest that increased expression of nm23-H1 in cancers of the upper aerodigestive tract may have different implications than elsewhere in the body...
  6. ncbi request reprint The expression and role of insulin-like growth factor II in malignant hemangiopericytomas
    K Pavelic
    Division of Molecular Medicine, Ruder Boskovic Institute, Zagreb, Croatia
    J Mol Med (Berl) 77:865-9. 1999
    ..Our data suggest that tumor cells produce IGF II, and that this in turn stimulates their proliferation by autocrine mechanisms...
  7. ncbi request reprint Collision tumour in the pelvic cavity: rectal leiomyosarcoma and prostate adenocarcinoma
    J Pavelic
    Division of Molecular Medicine, Ruder Boskovic Institute, Bijenicka 54, 10000 Zagreb, Croatia
    J Cancer Res Clin Oncol 126:95-100. 2000
    ..By contrast, in the leiomyosarcoma component, LOH was found at the DCC and p53 genes, proving that these two tumours did not arise from the same stem cell but represent two different neoplastic growths...
  8. ncbi request reprint Recent advances in molecular genetics of breast cancer
    K Pavelic
    Ruder Boskovic Institute, Division of Molecular Medicine, Bijenicka 54, P O Box 180, 10002 Zagreb, Croatia
    J Mol Med (Berl) 79:566-73. 2001
    ....
  9. ncbi request reprint Molecular pathology of hemangiopericytomas accompanied by severe hypoglycemia: oncogenes, tumor-suppressor genes and the insulin-like growth factor family
    K Pavelic
    Division of Molecular Medicine Ruder Bosković Institute, Zagreb, Croatia
    J Cancer Res Clin Oncol 124:307-14. 1998
    ..IGF ligands together with IGF IR could be responsible for hypoglycemia and perhaps the transformed phenotype...
  10. ncbi request reprint Insulin-like growth factor family in malignant haemangiopericytomas: the expression and role of insulin-like growth factor I receptor
    K Pavelic
    Division of Molecular Medicine, Ruder Boskovic Institute, HR 10000 Zagreb, Croatia
    J Pathol 188:69-75. 1999
    ..The data suggest that IGF IR may play an important role in the genesis and progression of malignant haemangiopericytomas...
  11. pmc nm23-H1 expression and loss of heterozygosity in colon adenocarcinoma
    S Kapitanovic
    Division of Molecular Medicine, Rudjer Boskovic Institute, HR 10000 Zagreb, Croatia
    J Clin Pathol 57:1312-8. 2004
    ....
  12. ncbi request reprint Detection and typing of human papillomaviruses by polymerase chain reaction in cervical scrapes of Croatian women with abnormal cytology
    M Grce
    Ruder Boskovic Institute, Division of Molecular Medicine, Zagreb, Croatia
    Eur J Epidemiol 13:645-51. 1997
    ..5 to 61.1% along with the severity of the cervical intraepithelial neoplasia (CIN I-IV). HPV type 6/11 was strongly associated with CIN I (33.8%), HPV type 31 with CIN II (22.9%), and HPV type 16 with CIN III (50%)...
  13. ncbi request reprint Detection and typing of human papillomaviruses by means of polymerase chain reaction and fragment length polymorphism in male genital lesions
    M Grce
    Division of Molecular Medicine, Ruder Boskovic Institute, Zagreb, Croatia
    Anticancer Res 20:2097-102. 2000
    ..The male population, indeed, represents a reservoir of HPV infection and directly influences cervical cancerogenesis...
  14. doi request reprint The novel phosphoramidate derivatives of NSAID 3-hydroxypropylamides: synthesis, cytostatic and antiviral activity evaluations
    K Wittine
    Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulicev trg 20, HR 10000 Zagreb, Croatia
    Eur J Med Chem 44:143-51. 2009
    ....
  15. doi request reprint Analysis of selected genes in neuroendocrine tumours: insulinomas and phaeochromocytomas
    R Hrascan
    Department of Biochemical Engineering, Faculty of Food Technology and Biotechnology, University of Zagreb, Zagreb, Croatia
    J Neuroendocrinol 20:1015-22. 2008
    ..Our findings may contribute to a better understanding of the genetic profile of neuroendocrine tumours...
  16. pmc NF1 gene loss of heterozygosity and expression analysis in sporadic colon cancer
    T Cacev
    Division of Molecular Medicine, Ruder Boskovic Institute, Bijenicka c 54, HR 10000 Zagreb, Croatia
    Gut 54:1129-35. 2005
    ..This is the first study to investigate the role of NF1 in sporadic colon cancer...
  17. ncbi request reprint Comparison of five different polymerase chain reaction methods for detection of human papillomavirus in cervical cell specimens
    K Husnjak
    Division of Molecular Medicine, Ruder Boskovic Institute, Bijenicka54, 10000, Zagreb, Croatia
    J Virol Methods 88:125-34. 2000
    ....
  18. ncbi request reprint Submerged gel electrophoresis on Spreadex gels--a new method for APC gene mutation detection
    S Kapitanovic
    Division of Molecular Medicine, Ruder Boskovic Institute, Zagreb, Croatia
    J Mol Med (Berl) 79:333-7. 2001
    ..Our results showed that electrophoresis using Spreadex gels provides a simple and rapid non-radioactive method for determination of the most-frequent germ-line mutations in the APC gene...
  19. ncbi request reprint Loss of heterozygosity of DPC4 tumor suppressor gene in human sporadic colon cancer
    M P Had ija
    Division of Molecular Medicine, Ruder Boskovic Insitute, Zagreb, Croatia
    J Mol Med (Berl) 79:128-32. 2001
    ..It can be concluded that inactivation of the DPC4 gene plays a role in a multistep process of outgrowth and progression of colon cancer...
  20. ncbi request reprint The p53 and nm23-H1 genes are not deleted in oral benign epithelial lesions
    J Pavelic
    Division of Molecular Medicine, Ruder Boskovic Institute, Zagreb, Croatia
    Anticancer Res 18:3527-31. 1998
    ..Alternatively, p53 and nm23-H1 may have no relation to oral lesion formation, and cannot presently be considered as an early step in benign, tissue transformation...
  21. ncbi request reprint Molecular genetics of malignant insulinoma
    K Pavelic
    Department of Molecular Medicine, Ruder Boskovic Institute, Zagreb, Croatia
    Anticancer Res 16:1707-17. 1996
    ....
  22. ncbi request reprint Expand Long PCR for fragile X mutation detection
    S Hecimovic
    Division of Molecular Medicine, Ruder Boskovic Institute, Zagreb, Croatia
    Clin Genet 52:147-54. 1997
    ..In this paper we propose a new strategy for molecular diagnosis of the fragile X syndrome in which our Expand Long PCR assay is used as the first screening test for fragile X mutation detection...
  23. ncbi request reprint Loss of heterozygosity and protein expression of APC gene in renal cell carcinomas
    N Pecina-Slaus
    Division of Molecular Medicine, Ruder Boskovic Institute, Zagreb, Croatia
    J Mol Med (Berl) 77:446-53. 1999
    ..Out results suggest that the APC tumor suppressor gene plays a role in renal carcinogenesis. Alterations in this gene are responsible for tumor evolution and progression, but cannot be considered as a first event in tumor initiation...
  24. ncbi request reprint DNA analysis of the fragile X syndrome in an at risk pediatric population in croatia: simple clinical preselection criteria can considerably improve the cost-effectiveness of fragile X screening studies
    S Hecimovic
    Division of Molecular Medicine, Ruder Boskovic Institute, Children s Hospital Zagreb, Croatia
    Hum Hered 48:256-65. 1998
    ..Our results also indicate that this syndrome is underdiagnosed in Croatia and that a further effort must be made to detect unrecognised cases...
  25. ncbi request reprint The novel primaquine derivatives of N-alkyl, cycloalkyl or aryl urea: synthesis, cytostatic and antiviral activity evaluations
    G Dzimbeg
    Faculty of Pharmacy and Biochemistry, A Kovacica 1, HR 10000 Zagreb, Croatia
    Eur J Med Chem 43:1180-7. 2008
    ..normal fibroblasts was found for ureas 3c, 3d and 3g. Results of broad antiviral evaluation showed that pyridine and phenethyl derivatives of urea 3h and 3g exhibited some selective inhibition against cytomegalovirus...
  26. ncbi request reprint Synthesis and in vitro antitumor effect of diclofenac and fenoprofen thiolated and nonthiolated polyaspartamide-drug conjugates
    M Barbaric
    Faculty of Pharmacy and Biochemistry, University of Zagreb, A Kovacica 1, HR 10000 Zagreb, Croatia
    Eur J Med Chem 42:20-9. 2007
    ....
  27. doi request reprint The new 5- or 6-azapyrimidine and cyanuric acid derivatives of l-ascorbic acid bearing the free C-5 hydroxy or C-4 amino group at the ethylenic spacer: CD-spectral absolute configuration determination and biological activity evaluations
    K Wittine
    Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulicev trg 20, HR 10000 Zagreb, Croatia
    Eur J Med Chem 46:2770-85. 2011
    ..Marked anticancer efficacy of compound 2 supports further in vivo investigation into its possible clinical utility...
  28. pmc Human papillomavirus, cytomegalovirus, and adeno-associated virus infections in pregnant and nonpregnant women with cervical intraepithelial neoplasia
    M Grce
    Division of Molecular Medicine, Rudjer Boskovic Institute, University of Zagreb, 10000 Zagreb, Croatia
    J Clin Microbiol 42:1341-4. 2004
    ..358) than HCMV was. Increased HPV infection was strongly associated (P < 0.001) with a higher CIN grade, but there is no evidence that AAV 2 and HCMV infections have any impact on CIN development...
  29. ncbi request reprint Screening for fragile X syndrome: results from a school for mentally retarded children
    S Hecimovic
    Division of Molecular Medicine, Ruder Boskovic Institute, Zagreb, Croatia
    Acta Paediatr 91:535-9. 2002
    ..However, since at the time of diagnosis all affected families had a second or even a third child born, earlier diagnosis should be considered to provide greater benefit to fragile X families...
  30. ncbi request reprint Evaluation of genital human papillomavirus infections by polymerase chain reaction among Croatian women
    M Grce
    Rudjer Boskovic Institute, Division of Molecular Medicine, Bijenicka 54, 10000 Zagreb, Croatia
    Anticancer Res 21:579-84. 2001
    ..Our results indicated that HPV infections, especially those with HPV 16, represent a significant public health concern in Croatia...
  31. ncbi request reprint A simple and rapid analysis of triplet repeat diseases by expand long PCR
    S Hecimovic
    Division of Molecular Medicine, Ruder Boskovic Institute, Zagreb, Croatia
    Clin Chem Lab Med 39:1259-62. 2001
    ..We suggest the use of Expand Long PCR for routine molecular diagnosis of triplet repeat diseases, and present such analysis of the fragile X syndrome, myotonic dystrophy and Huntington's disease...