Zeljko M Svedruzić

Summary

Affiliation: Faculty of Science
Country: Croatia

Publications

  1. doi request reprint Decrease in catalytic capacity of γ-secretase can facilitate pathogenesis in sporadic and Familial Alzheimer's disease
    Zeljko M Svedruzić
    Medical Biochemistry, PB Rab, Faculty of Medicine, University of Rijeka, Rab, Croatia Department of Biotechnology, University of Rijeka, Rijeka, Croatia Electronic address
    Mol Cell Neurosci 67:55-65. 2015
  2. pmc Modulators of γ-secretase activity can facilitate the toxic side-effects and pathogenesis of Alzheimer's disease
    Zeljko M Svedruzić
    Medical Biochemistry, PB Rab, Faculty of Medicine, University of Rijeka, Rab, Croatia
    PLoS ONE 8:e50759. 2013
  3. pmc Modulation of γ-secretase activity by multiple enzyme-substrate interactions: implications in pathogenesis of Alzheimer's disease
    Zeljko M Svedruzić
    Medical Biochemistry, Faculty of Medicine, University of Rijeka, Rab, Croatia
    PLoS ONE 7:e32293. 2012

Detail Information

Publications3

  1. doi request reprint Decrease in catalytic capacity of γ-secretase can facilitate pathogenesis in sporadic and Familial Alzheimer's disease
    Zeljko M Svedruzić
    Medical Biochemistry, PB Rab, Faculty of Medicine, University of Rijeka, Rab, Croatia Department of Biotechnology, University of Rijeka, Rijeka, Croatia Electronic address
    Mol Cell Neurosci 67:55-65. 2015
    ..Alzheimer's disease can be a result of an age-induced disparity between increase in cellular metabolism of Aβ peptides and decrease in maximal activity of a membrane-embedded protease γ-secretase...
  2. pmc Modulators of γ-secretase activity can facilitate the toxic side-effects and pathogenesis of Alzheimer's disease
    Zeljko M Svedruzić
    Medical Biochemistry, PB Rab, Faculty of Medicine, University of Rijeka, Rab, Croatia
    PLoS ONE 8:e50759. 2013
    ..We describe how different drug-candidates can modulate γ-secretase activity in cells, by studying how DAPT affects changes in γ-secretase activity caused by gradual increase in Aβ metabolism...
  3. pmc Modulation of γ-secretase activity by multiple enzyme-substrate interactions: implications in pathogenesis of Alzheimer's disease
    Zeljko M Svedruzić
    Medical Biochemistry, Faculty of Medicine, University of Rijeka, Rab, Croatia
    PLoS ONE 7:e32293. 2012
    ....