Dubravka Hranilovic

Summary

Affiliation: Faculty of Science
Country: Croatia

Publications

  1. ncbi Serotonin transporter gene promoter (5-HTTLPR) and intron 2 (VNTR) polymorphisms in Croatian suicide victims
    Dubravka Hranilovic
    Laboratory of Neurochemistry and Molecular Neurobiology, Rudjer Boskovic Institute, Zagreb, Croatia
    Biol Psychiatry 54:884-9. 2003
  2. ncbi 5-HT2A receptor gene polymorphisms in Croatian subjects with autistic disorder
    Dubravka Hranilovic
    Department of Animal Physiology, Faculty of Science, University of Zagreb, and Psychiatric Hospital for Children and Youth, Zagreb, Croatia
    Psychiatry Res 178:556-8. 2010
  3. ncbi Hyperserotonemia in adults with autistic disorder
    Dubravka Hranilovic
    Department of Animal Physiology, Faculty of Science, University of Zagreb, Rooseveltov trg 6, 10 000 Zagreb, Croatia
    J Autism Dev Disord 37:1934-40. 2007
  4. ncbi Hyperserotonemia in autism: the potential role of 5HT-related gene variants
    Dubravka Hranilovic
    Department of Animal Physiology, Faculty of Science, University of Zagreb, Zagreb, Croatia
    Coll Antropol 32:75-80. 2008
  5. ncbi Functional promoter polymorphism of the neuronal isoform of tryptophan hydroxylase (Tph2) in suicide
    Jasminka Stefulj
    Laboratory of Neurochemistry and Molecular Neurobiology, Rudjer Boskovic Institute, Zagreb, Croatia
    Psychiatry Res 186:446-7. 2011
  6. ncbi Alcohol dependence and polymorphisms of serotonin-related genes: association studies
    Gordana Mokrovic
    Department of Molecular Biology, Ruder Bogkovid Institute, Zagreb, Croatia
    Coll Antropol 32:127-31. 2008
  7. ncbi Hyperserotonemia in autism: activity of 5HT-associated platelet proteins
    Dubravka Hranilovic
    Faculty of Science, University of Zagreb, Rooseveltov trg 6, 10 000, Zagreb, Croatia
    J Neural Transm 116:493-501. 2009
  8. ncbi Serotonin transporter promoter and intron 2 polymorphisms: relationship between allelic variants and gene expression
    Dubravka Hranilovic
    Laboratory of Neurochemistry and Molecular Neurobiology, Department of Molecular Genetics, Rudjer Boskovic Institute, Zagreb, Croatia
    Biol Psychiatry 55:1090-4. 2004
  9. ncbi Anxiety-like behavior and cognitive flexibility in adult rats perinatally exposed to increased serotonin concentrations
    Sofia Blazevic
    Department of Animal Physiology, Faculty of Science, University of Zagreb, Rooseveltov trg 6, HR 10 000 Zagreb, Croatia
    Behav Brain Res 230:175-81. 2012
  10. ncbi The effects of the perinatal treatment with 5-hydroxytryptophan or tranylcypromine on the peripheral and central serotonin homeostasis in adult rats
    Dubravka Hranilovic
    Department of Animal Physiology, Division of Biology, Faculty of Science, University of Zagreb, Rooseveltov trg 6, 10000 Zagreb, Croatia
    Neurochem Int 59:202-7. 2011

Collaborators

Detail Information

Publications12

  1. ncbi Serotonin transporter gene promoter (5-HTTLPR) and intron 2 (VNTR) polymorphisms in Croatian suicide victims
    Dubravka Hranilovic
    Laboratory of Neurochemistry and Molecular Neurobiology, Rudjer Boskovic Institute, Zagreb, Croatia
    Biol Psychiatry 54:884-9. 2003
    ....
  2. ncbi 5-HT2A receptor gene polymorphisms in Croatian subjects with autistic disorder
    Dubravka Hranilovic
    Department of Animal Physiology, Faculty of Science, University of Zagreb, and Psychiatric Hospital for Children and Youth, Zagreb, Croatia
    Psychiatry Res 178:556-8. 2010
    ..Significant overrepresentation of the G allele and the GG genotype of the -1438 A/G polymorphism was observed in group of autistic subjects, supporting the possible involvement of the 5-HT2A receptor in the development of autism...
  3. ncbi Hyperserotonemia in adults with autistic disorder
    Dubravka Hranilovic
    Department of Animal Physiology, Faculty of Science, University of Zagreb, Rooseveltov trg 6, 10 000 Zagreb, Croatia
    J Autism Dev Disord 37:1934-40. 2007
    ..However, significant negative relationship was observed between PSL and speech development, indicating the relationship between the peripheral 5HT concentrations and verbal abilities in autistic subjects...
  4. ncbi Hyperserotonemia in autism: the potential role of 5HT-related gene variants
    Dubravka Hranilovic
    Department of Animal Physiology, Faculty of Science, University of Zagreb, Zagreb, Croatia
    Coll Antropol 32:75-80. 2008
    ..These results suggest a possible synergistic effect of genes regulating 5HT synthesis/degradation in dysregulation of the peripheral 5HT homeostasis of autistic patients...
  5. ncbi Functional promoter polymorphism of the neuronal isoform of tryptophan hydroxylase (Tph2) in suicide
    Jasminka Stefulj
    Laboratory of Neurochemistry and Molecular Neurobiology, Rudjer Boskovic Institute, Zagreb, Croatia
    Psychiatry Res 186:446-7. 2011
    ..No significant differences were found between the groups. Obtained results do not support involvement of the investigated polymorphism in the susceptibility to suicide completion...
  6. ncbi Alcohol dependence and polymorphisms of serotonin-related genes: association studies
    Gordana Mokrovic
    Department of Molecular Biology, Ruder Bogkovid Institute, Zagreb, Croatia
    Coll Antropol 32:127-31. 2008
    ..The increase of sample size (in progress) is expected to enable search of more subtle differences, as well as re-evaluation of these preliminary findings...
  7. ncbi Hyperserotonemia in autism: activity of 5HT-associated platelet proteins
    Dubravka Hranilovic
    Faculty of Science, University of Zagreb, Rooseveltov trg 6, 10 000, Zagreb, Croatia
    J Neural Transm 116:493-501. 2009
    ..The results suggest a possibility of upregulation of monoaminergic synthesis/degradation and, probably consequential, downregulation of 5HT(2A)r in autistic subjects...
  8. ncbi Serotonin transporter promoter and intron 2 polymorphisms: relationship between allelic variants and gene expression
    Dubravka Hranilovic
    Laboratory of Neurochemistry and Molecular Neurobiology, Department of Molecular Genetics, Rudjer Boskovic Institute, Zagreb, Croatia
    Biol Psychiatry 55:1090-4. 2004
    ..02). CONCLUSIONS: Our results indicate weak individual influence, but possible combined effect, of 5-HTTLPR and VNTR-2 polymorphisms on 5-HTT gene expression...
  9. ncbi Anxiety-like behavior and cognitive flexibility in adult rats perinatally exposed to increased serotonin concentrations
    Sofia Blazevic
    Department of Animal Physiology, Faculty of Science, University of Zagreb, Rooseveltov trg 6, HR 10 000 Zagreb, Croatia
    Behav Brain Res 230:175-81. 2012
    ....
  10. ncbi The effects of the perinatal treatment with 5-hydroxytryptophan or tranylcypromine on the peripheral and central serotonin homeostasis in adult rats
    Dubravka Hranilovic
    Department of Animal Physiology, Division of Biology, Faculty of Science, University of Zagreb, Rooseveltov trg 6, 10000 Zagreb, Croatia
    Neurochem Int 59:202-7. 2011
    ..Further studies are planned in order to explore the nature of the different disturbances of 5HT homeostasis induced by the two compounds, and their results are expected to shed some light on the role of hyperserotonemia in autism...
  11. ncbi Emotional response in dopamine D2L receptor-deficient mice
    Dubravka Hranilovic
    Department of Animal Physiology, Faculty of Science, University of Zagreb, Zagreb, Croatia
    Behav Brain Res 195:246-50. 2008
    ..Our findings contribute to a better understanding of the molecular and cellular mechanisms underlying emotional responses...
  12. ncbi Rats with constitutionally upregulated/downregulated platelet 5HT transporter: differences in anxiety-related behavior
    Dubravka Hranilovic
    Laboratory of Neurochemistry and Molecular Neurobiology, Department of Molecular Biology, Rudjer Boskovic Institute, Bijenicka 54, HR 10 000 Zagreb, Croatia
    Behav Brain Res 165:271-7. 2005
    ..The results suggest that as a result of selection process, a specific component of anxiety-related behavior (i.e. exploratory activity directed towards a novel environment and conspecifics) has been affected in Wistar-Zagreb 5HT rats...