Carolyn B Coulam

Summary

Publications

  1. ncbi request reprint Natural killer cell functional activity suppression by intravenous immunoglobulin, intralipid and soluble human leukocyte antigen-G
    Roumen G Roussev
    Millenova Immunology Laboratories, Chicago, IL 60611, USA
    Am J Reprod Immunol 57:262-9. 2007
  2. ncbi request reprint Which thrombophilic gene mutations are risk factors for recurrent pregnancy loss?
    Cyle S Goodman
    Millenova Immunology Laboratories, 233 East Erie Street, Chicago, IL 60611, USA
    Am J Reprod Immunol 56:230-6. 2006
  3. ncbi request reprint Understanding the immunobiology of pregnancy and applying it to treatment of recurrent pregnancy loss
    C B Coulam
    The Center for Human Reproduction, Chicago, Illinois 60610, USA
    Early Pregnancy 4:19-29. 2000
  4. ncbi request reprint Antiphospholipid antibody round table report
    Carolyn B Coulam
    Sher Institute for Reproductive Medicine, Millenova Immunology Laboratories, Chicago, IL, USA
    Am J Reprod Immunol 48:262-5. 2002
  5. pmc Is intravenous immunoglobulins (IVIG) efficacious in early pregnancy failure? A critical review and meta-analysis for patients who fail in vitro fertilization and embryo transfer (IVF)
    David A Clark
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    J Assist Reprod Genet 23:1-13. 2006
  6. doi request reprint A search to identify genetic risk factors for endometriosis
    Carlos Rotman
    Oak Brook Institute of Endoscopy, Oak Brook, IL, USA
    Am J Reprod Immunol 69:92-5. 2013
  7. doi request reprint Does immunotherapy for treatment of reproductive failure enhance live births?
    Carolyn B Coulam
    Reproductive Medicine Institute, Evanston, IL, USA
    Am J Reprod Immunol 67:296-304. 2012
  8. doi request reprint Vascular endothelial growth factor gene polymorphisms and recurrent pregnancy loss
    Carolyn B Coulam
    Pregnancy Success Center of the Rinehart Center for Reproductive Medicine, Chicago, IL, USA
    Am J Reprod Immunol 59:301-5. 2008
  9. doi request reprint Comparison of thrombophilic gene mutations among patients experiencing recurrent miscarriage and deep vein thrombosis
    Carolyn B Coulam
    Rinehart Center for Reproductive Medicine, Evanston, IL, USA
    Am J Reprod Immunol 60:426-31. 2008
  10. doi request reprint Thrombophilic gene polymorphisms are risk factors for unexplained infertility
    Carolyn B Coulam
    Pregnancy Success Center and Rinehart Center for Reproductive Medicine, Chicago, Illinois, USA
    Fertil Steril 91:1516-7. 2009

Collaborators

Detail Information

Publications29

  1. ncbi request reprint Natural killer cell functional activity suppression by intravenous immunoglobulin, intralipid and soluble human leukocyte antigen-G
    Roumen G Roussev
    Millenova Immunology Laboratories, Chicago, IL 60611, USA
    Am J Reprod Immunol 57:262-9. 2007
    ..The purpose of this study was to compare the ability of intravenous immunoglobulin (IVIg), intralipid and soluble human leukocyte antigen (sHLA)-G to suppress natural killer (NK) cell cytotoxicity in an in vitro assay...
  2. ncbi request reprint Which thrombophilic gene mutations are risk factors for recurrent pregnancy loss?
    Cyle S Goodman
    Millenova Immunology Laboratories, 233 East Erie Street, Chicago, IL 60611, USA
    Am J Reprod Immunol 56:230-6. 2006
    ..Thrombophilia has been associated with poor obstetrical outcomes. To determine the association of specific inherited thrombophilias and recurrent pregnancy loss, 10 thrombophilic genes were investigated...
  3. ncbi request reprint Understanding the immunobiology of pregnancy and applying it to treatment of recurrent pregnancy loss
    C B Coulam
    The Center for Human Reproduction, Chicago, Illinois 60610, USA
    Early Pregnancy 4:19-29. 2000
    ..Based upon information gleaned from these reviews an approach to diagnosis and treatment of recurrent pregnancy loss is presented...
  4. ncbi request reprint Antiphospholipid antibody round table report
    Carolyn B Coulam
    Sher Institute for Reproductive Medicine, Millenova Immunology Laboratories, Chicago, IL, USA
    Am J Reprod Immunol 48:262-5. 2002
  5. pmc Is intravenous immunoglobulins (IVIG) efficacious in early pregnancy failure? A critical review and meta-analysis for patients who fail in vitro fertilization and embryo transfer (IVF)
    David A Clark
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    J Assist Reprod Genet 23:1-13. 2006
    ..Systematic reviews generating inconclusive results have focused on methodological rigor to the exclusion of biological plausibility...
  6. doi request reprint A search to identify genetic risk factors for endometriosis
    Carlos Rotman
    Oak Brook Institute of Endoscopy, Oak Brook, IL, USA
    Am J Reprod Immunol 69:92-5. 2013
    ..To search for molecular markers of endometriosis the following polymorphisms: p53 codon 72 Pro (apoptosis), TNF alpha-308 (inflammation), VEGF-1164AA (angiogenesis), and SOD2 (oxidative stress) were investigated...
  7. doi request reprint Does immunotherapy for treatment of reproductive failure enhance live births?
    Carolyn B Coulam
    Reproductive Medicine Institute, Evanston, IL, USA
    Am J Reprod Immunol 67:296-304. 2012
    ..Immunotherapy for treatment of reproductive failure enhances live birth but only in those women displaying abnormal immunologic risk factors...
  8. doi request reprint Vascular endothelial growth factor gene polymorphisms and recurrent pregnancy loss
    Carolyn B Coulam
    Pregnancy Success Center of the Rinehart Center for Reproductive Medicine, Chicago, IL, USA
    Am J Reprod Immunol 59:301-5. 2008
    ..The aim of this study was to confirm or refute the relationship of VEGF -1154 to recurrent pregnancy loss (RPL)...
  9. doi request reprint Comparison of thrombophilic gene mutations among patients experiencing recurrent miscarriage and deep vein thrombosis
    Carolyn B Coulam
    Rinehart Center for Reproductive Medicine, Evanston, IL, USA
    Am J Reprod Immunol 60:426-31. 2008
    ..This study was undertaken to compare the frequencies of nine inherited thrombophilias among women with a history of recurrent pregnancy loss with individuals experiencing deep venous thrombosis and fertile controls...
  10. doi request reprint Thrombophilic gene polymorphisms are risk factors for unexplained infertility
    Carolyn B Coulam
    Pregnancy Success Center and Rinehart Center for Reproductive Medicine, Chicago, Illinois, USA
    Fertil Steril 91:1516-7. 2009
    ....
  11. doi request reprint How to predict implantation? No correlation between embryonic aneuploidy and soluble human leukocyte antigen G-concentrations
    Carolyn B Coulam
    Rinehart Center for Reproductive Medicine, Evanston, Illinois, USA
    Fertil Steril 91:2408-13. 2009
    ..To determine if soluble human leukocyte antigen-G (sHLA-G) concentrations in spent culture media may assist in identifying the normal embryo for implantation...
  12. pmc Discordance among blastomeres renders preimplantation genetic diagnosis for aneuploidy ineffective
    C B Coulam
    Pregnancy Success Center, Rinehart Center for Reproductive Medicine, 233 East Erie St, Suite 500, Chicago, IL 60611, USA
    J Assist Reprod Genet 24:37-41. 2007
    ..To investigate the contribution of discordance among blastomeres from the same embryo in the interpretation of blastomeres biopsied from day 3 embryos...
  13. ncbi request reprint Multiple thrombophilic gene mutations rather than specific gene mutations are risk factors for recurrent miscarriage
    Carolyn B Coulam
    Pregnancy Success Center or the Rinehart Center for Reproductive Medicine, Chicago, IL, USA
    Am J Reprod Immunol 55:360-8. 2006
    ..We compared the prevalence of 10 thrombophilic gene mutations among women with a history of recurrent miscarriages and fertile control women...
  14. ncbi request reprint Role of p53 codon 72 polymorphism in recurrent pregnancy loss
    C B Coulam
    Pregnancy Success Centre of the Rinehart Centre for Reproductive Medicine, Chicago, IL, USA
    Reprod Biomed Online 12:378-82. 2006
    ..It is concluded that p53 codon 72 polymorphisms do not serve as a susceptibility factor affecting the chances of miscarriage in an unselected population...
  15. ncbi request reprint Chemical pregnancies: immunologic and ultrasonographic studies
    Carolyn B Coulam
    Sher Institute for Reproductive Medicine and Millenova Immunology Laboratories, Chicago, IL 60610, USA
    Am J Reprod Immunol 48:323-8. 2002
    ..In addition ultrasonographic measurement of gestational sac size from 24 to 35 days from last menstrual period (LMP) were compared between chemical pregnancies and other pregnancy outcomes...
  16. pmc Correlation of NK cell activation and inhibition markers with NK cytoxicity among women experiencing immunologic implantation failure after in vitro fertilization and embryo transfer
    Carolyn B Coulam
    Sher Institute for Reproductive Medicine, Chicago, Illinois, USA
    J Assist Reprod Genet 20:58-62. 2003
    ..Lastly, we wish to determine the ability of each of these markers to predict pregnancy outcome after IVF/ET (in vitro fertilization/embryo transfer)...
  17. ncbi request reprint Increasing circulating T-cell activation markers are linked to subsequent implantation failure after transfer of in vitro fertilized embryos
    Carolyn B Coulam
    Sher Institute for Reproductive Medicine, Chicago, IL, USA
    Am J Reprod Immunol 50:340-5. 2003
    ..Most of the literature addresses the importance of natural killer (NK) cells in this process. The purpose of the current study is to examine the role of circulating T cells in implantation failure...
  18. ncbi request reprint Multiple thrombophilic gene mutations are risk factors for implantation failure
    Carolyn B Coulam
    Pregnancy Success Centre of the Rinehart Centre for Reproductive Medicine, Chicago, IL, USA
    Reprod Biomed Online 12:322-7. 2006
    ..0004). It is concluded that inherited thrombophilias are associated with implantation failure. This association is manifest by total number of mutations as well as with PAI-1 mutations...
  19. pmc Association of progesterone receptor polymorphisms with recurrent implantation failure after in vitro fertilization and embryo transfer
    Carolyn B Coulam
    Pregnancy Success Center of Rinehart Center for Reproductive Medicine, Evanston, IL, USA
    J Assist Reprod Genet 25:119-22. 2008
    ..The actions of progesterone are mediated by the progesterone receptor. Polymorphic variants of human progesterone receptor genes have been implicated in implantation failure...
  20. doi request reprint Preimplantation factor negates embryo toxicity and promotes embryo development in culture
    Christopher W Stamatkin
    BioIncept LLC CARI Research Institute, Chicago, IL, USA
    Reprod Biomed Online 23:517-24. 2011
    ..sPIF-based therapy for reducing recurrent pregnancy loss and improving lagging cultured IVF embryo development should be explored...
  21. doi request reprint Duration of intralipid's suppressive effect on NK cell's functional activity
    Roumen G Roussev
    Millenova Immunology Laboratories, Chicago, IL, USA
    Am J Reprod Immunol 60:258-63. 2008
    ..Evidence from both animal and human studies suggests that intralipid administered intravenously may enhance implantation and maintenance of pregnancy when the patient has an abnormal NK cell level or function...
  22. doi request reprint Preimplantation factor inhibits circulating natural killer cell cytotoxicity and reduces CD69 expression: implications for recurrent pregnancy loss therapy
    Roumen G Roussev
    CARI Reproductive Institute BioIncept LLC, Chicago, IL, USA
    Reprod Biomed Online 26:79-87. 2013
    ..The sPIF effect on NK cells was targeted, indicating specific action. Overall, sPIF may represent a safe, effective and nontoxic immune-based therapy against RPL...
  23. pmc HLA-G and its role in implantation (review)
    Roumen G Roussev
    Millenova Immunology Laboratories, Chicago, IL, USA
    J Assist Reprod Genet 24:288-95. 2007
    ..Human leukocyte antigen G (HLA-G) is thought to play a key role in implantation by modulating cytokine secretion to control trophopblastic cell invasion and to maintain a local immunotolerance...
  24. doi request reprint Interleukin 1 receptor antagonist gene polymorphisms are not risk factors for recurrent pregnancy loss: evaluation of couples
    Seth Levrant
    Reproductive Health, Tinley Park, IL, USA
    Am J Reprod Immunol 60:224-8. 2008
    ..This study was undertaken to compare the frequency of IL-1RN 2 alleles among both male and female partners of couples experiencing recurrent pregnancy loss with that of fertile control couples...
  25. ncbi request reprint Y-chromosome microdeletions and recurrent pregnancy loss
    Sheri Dewan
    Andrology Laboratory Services Inc, Chicago, Illinois, USA
    Fertil Steril 85:441-5. 2006
    ..To determine the prevalence of Y-chromosome microdeletions in recurrent pregnancy loss (RPL) couples as compared with couples with male factor infertility and fertile couples...
  26. ncbi request reprint p53 tumour suppressor gene polymorphism is associated with recurrent implantation failure
    C Kay
    Andrology Laboratory Services, Chicago, IL, USA
    Reprod Biomed Online 13:492-6. 2006
    ..It is concluded that p53 codon 72 polymorphisms may serve as a susceptibility factor affecting the chances of recurrent implantation after IVF or embryo transfer...
  27. pmc PreImplantation Factor (PIF) correlates with early mammalian embryo development-bovine and murine models
    Christopher W Stamatkin
    BioIncept LLC CARI Research Institute, Chicago, IL, USA
    Reprod Biol Endocrinol 9:63. 2011
    ..To determine the role of PIF in post-fertilization embryo development, we measured the peptide's concentration in the culture medium and tested endogenous PIF's potential trophic effects and direct interaction with the embryo...
  28. doi request reprint Cryopreservation of human sperm in a lecithin-supplemented freezing medium
    Rajasingam S Jeyendran
    Andrology Laboratory Services Inc, Chicago, Illinois 60611, USA
    Fertil Steril 90:1263-5. 2008
    ..To reduce the risk of contamination, the cryoprotective property of phospholipids extracted from lecithin was evaluated and found to be effective when supplemented with dimethyl sulfoxide and glycerol...
  29. pmc Introduction to special issue on implantation
    David A Clark
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    J Assist Reprod Genet 24:282-3. 2007