Transmembrane signaling proteoglycansJohn R Couchman
Department of Biomedical Sciences, University of Copenhagen, Copenhagen, 2200 Denmark
Annu Rev Cell Dev Biol 26:89-114. 2010
..Here some of the latest developments in the field are examined in hopes of stimulating further interest in this fascinating group of molecules...
An introduction to proteoglycans and their localizationJohn R Couchman
Department of Biomedical Sciences, University of Copenhagen, Copenhagen N, Denmark
J Histochem Cytochem 60:885-97. 2012
..Included are some remarks on proteoglycan and glycosaminoglycan localization techniques, with reference to the special physicochemical properties of these complex molecules...
The newcomer in the integrin family: integrin α9 in biology and cancerAnette M Høye
Department of Biomedical Sciences, The Faculty of Health and Medical Sciences, and Biotech Research and Innovation Centre BRIC, University of Copenhagen, Copenhagen Biocenter, Ole Maaløes Vej 5, Copenhagen N 2200, Denmark
Adv Biol Regul 52:326-39. 2012
..This review gives an overview of the recent progress in α9β1-mediated biological and pathological processes, and discusses its potential as a target for cancer diagnosis and therapy...
Breast and ovarian cancers: a survey and possible roles for the cell surface heparan sulfate proteoglycansAtsuko Yoneda
Department of Biomedical Sciences, University of Copenhagen, Denmark
J Histochem Cytochem 60:9-21. 2012
..Both families of proteoglycans have been implicated in cellular responses to growth factors and morphogens, including many now associated with tumor progression...
Proteoglycans in health and disease: the multiple roles of syndecan sheddingTina Manon-Jensen
Deparment of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark
FEBS J 277:3876-89. 2010
..Here, recent research into the shedding of syndecans and its physiological relevance are assessed...
Heparan sulfate biosynthesis: methods for investigation of the heparanosomeHinke A B Multhaupt
Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark
J Histochem Cytochem 60:908-15. 2012
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Syndecan-1 and syndecan-4 are independent indicators in breast carcinomaMaria E Lendorf
Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark
J Histochem Cytochem 59:615-29. 2011
..These syndecans may, therefore, have distinct roles in regulating breast carcinoma cell behavior...
A collapsin response mediator protein 2 isoform controls myosin II-mediated cell migration and matrix assembly by trapping ROCK IIAtsuko Yoneda
Department of Biomedical Sciences, Faculty of Health Sciences, and Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark
Mol Cell Biol 32:1788-804. 2012
..This study provides a new insight into CRMP-2 as a controller of myosin II-mediated cellular functions through the inhibition of ROCK II in nonneuronal cells...
Heparan sulfate chain valency controls syndecan-4 function in cell adhesionSandeep Gopal
Department of Biomedical Sciences, University of Copenhagen, 2200 Copenhagen N, Denmark
J Biol Chem 285:14247-58. 2010
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