Research Topics
| Cecilia DiazSummaryAffiliation: Universidad de Costa Rica Country: Costa Rica Publications
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Detail Information
Publications
Modulation of the susceptibility of human erythrocytes to snake venom myotoxic phospholipases A(2): role of negatively charged phospholipids as potential membrane binding sitesC Diaz
Instituto Clodomiro Picado, Facultad de Microbiologia, Universidad de Costa Rica, San Jose, Costa Rica
Arch Biochem Biophys 391:56-64. 2001..The scarcity of anionic phospholipids in the outer leaflet of RBC could explain their resistance to the action of these PLA2s...
Chemical composition of Schinus molle essential oil and its cytotoxic activity on tumour cell linesCecilia Diaz
Instituto Clodomiro Picado, Facultad de Microbiologia, Universidad de Costa Rica, San Jose, Costa Rica
Nat Prod Res 22:1521-34. 2008..It would be interesting to elucidate the role that different components of the oil play in the effect observed here, since some of them could have potential anti-tumoural effects, either alone or in combination...
Characterization of events associated with apoptosis/anoikis induced by snake venom metalloproteinase BaP1 on human endothelial cellsCecilia Diaz
Instituto Clodomiro Picado, Facultad de Microbiologia, Universidad de Costa Rica, San Jose, Costa Rica
J Cell Biochem 94:520-8. 2005....
Experimental pathology of local tissue damage induced by Bothrops asper snake venomJose Maria Gutierrez
Instituto Clodomiro Picado, Facultad de Microbiologia, Universidad de Costa Rica, San Jose, Costa Rica
Toxicon 54:958-75. 2009..asper-induced local effects, and the search for novel toxin inhibitors represents a potential avenue for improving the treatment of this serious aspect of snakebite envenomation...
Cell death induced by Bothrops asper snake venom metalloproteinase on endothelial and other cell linesOscar Brenes
Departamento de Fisiologia, Escuela de Medicina, Universidad de Costa Rica, San Jose, Costa Rica
Exp Mol Pathol 88:424-32. 2010..Processes other than apoptosis could be also involved in the cell death mechanism mediated by BaP1 on BAEC...
Increments in cytokines and matrix metalloproteinases in skeletal muscle after injection of tissue-damaging toxins from the venom of the snake Bothrops asperAlexandra Rucavado
Instituto Clodomiro Picado, Facultad de Microbiologia, Escuela de Medicina, Universidad de Costa Rica, San Jose
Mediators Inflamm 11:121-8. 2002..MMPs do not seem to play a prominent role in the acute local pathological alterations induced by these toxins in this experimental model...
Hemorrhage induced by snake venom metalloproteinases: biochemical and biophysical mechanisms involved in microvessel damageJose Maria Gutierrez
Instituto Clodomiro Picado, Facultad de Microbiologia, Universidad de Costa Rica, San Jose, Costa Rica
Toxicon 45:997-1011. 2005..In addition, endothelial cells become more susceptible to blood flow-dependent shear stress, which further contributes to capillary wall disruption...
Leaf essential oil of Manekia naranjoana (Piperaceae) from Costa Rica and its cytotoxic activityCarlos Chaverri
Centro de Investigaciones en Productos Naturales and Escuela de Química, Universidad de Costa Rica, San Jose, Montes de Oca, San Pedro, 11501 2060 Costa Rica
Nat Prod Commun 6:145-8. 2011..This is the first report of the chemical composition of the essential oil obtained from this species...
Cytotoxic effect induced by retinoic acid loaded into galactosyl-sphingosine containing liposomes on human hepatoma cell linesCecilia Diaz
Instituto Clodomiro Picado, Facultad de Microbiologia, Universidad de Costa Rica, San Jose, Costa Rica
Int J Pharm 325:108-15. 2006....
Carotenoid composition and antioxidant activity of the raw and boiled fruit mesocarp of six varieties of Bactris gasipaesSorel Jatunov
Escuela de Medicina, Universidad de Costa Rica, Facultad de Microbiologia, Universidad de Costa Rica, San Jose, Costa Rica
Arch Latinoam Nutr 60:99-104. 2010..This is one of the first reports in carotenoid content and antioxidant activity in well typified varieties of Bactris gasipaes, whose results could have a positive impact in the consumption of certain peach palm varieties...
