Ugur Coskun

Summary

Publications

  1. ncbi request reprint Serum and ascitic fluid nitrate levels in patients with cirrhosis
    U Coskun
    Department of Internal Medicine, Gazi University Medical School, Ankara, Turkey
    Clin Chim Acta 306:127-32. 2001
  2. ncbi request reprint Serum P-selectin, soluble vascular cell adhesion molecule-I (s-VCAM-I) and soluble intercellular adhesion molecule-I (s-ICAM-I) levels in bladder carcinoma patients with different stages
    Ugur Coskun
    Gazi University Medical School, Department of Medical Oncology, Ankara, Turkey
    Int Immunopharmacol 6:672-7. 2006
  3. ncbi request reprint F-18 FDG uptake due to acinetobacter infection causing misinterpretation of treatment response in a lymphoma patient
    Ramazan Yildiz
    Departments of Medical Oncology, Gazi Hospital, Gazi University School of Medicine, 06500 Besevler Ankara, Turkey
    Clin Nucl Med 32:471-3. 2007
  4. pmc Synchronous testicular liposarcoma and prostate adenocarcinoma: a case report
    Umut Demirci
    Department of Medical Oncology Gazi University Medical Faculty, 06500, Besevler, Ankara, Turkey
    Cases J 3:27. 2010
  5. ncbi request reprint UFT plus oral folinic acid with alternating oral and intravenous vinorelbine in patients with metastatic breast cancer previously treated with anthracyclines and taxanes
    Ugur Coskun
    Department of Medical Oncology, Gazi University Medical School, Ankara, Turkey
    Onkologie 32:562-6. 2009
  6. ncbi request reprint Significance of serum vascular endothelial growth factor, insulin-like growth factor-I levels and nitric oxide activity in breast cancer patients
    Ugur Coskun
    Department of Medical Oncology, Gazi University Medical School, Turkey
    Breast 12:104-10. 2003
  7. ncbi request reprint Gemcitabine combined with uracil-tegafur in patients with advanced pancreatic cancer
    Ugur Coskun
    Department of Medical Oncology, Gazi University Medical School, Besevler, Ankara 06500, Turkey
    J Natl Med Assoc 101:761-4. 2009
  8. ncbi request reprint Serum hepatocyte growth factor and interleukin-6 levels can distinguish patients with primary or metastatic liver tumors from those with benign liver lesions
    U Coskun
    Department of Medical Oncology, Gazi University Medical School, Ankara, Turkey
    Neoplasma 51:209-13. 2004
  9. pmc Effect of tamoxifen on serum IL-18, vascular endothelial growth factor and nitric oxide activities in breast carcinoma patients
    U Coskun
    Department of Medical Oncology, Gazi University Medical School, Ankara, Turkey
    Clin Exp Immunol 137:546-51. 2004
  10. doi request reprint Peritumoral lymphatic microvessel density associated with tumor progression and poor prognosis in gastric carcinoma
    Ugur Coskun
    Department of Medical Oncology, Gazi University Medical School, Ankara, Turkey
    J Surg Res 164:110-5. 2010

Detail Information

Publications93

  1. ncbi request reprint Serum and ascitic fluid nitrate levels in patients with cirrhosis
    U Coskun
    Department of Internal Medicine, Gazi University Medical School, Ankara, Turkey
    Clin Chim Acta 306:127-32. 2001
    ..The purpose of this study was to reveal the clinical importance of nitric oxide levels and the possible factors related to this increase in patients with cirrhosis...
  2. ncbi request reprint Serum P-selectin, soluble vascular cell adhesion molecule-I (s-VCAM-I) and soluble intercellular adhesion molecule-I (s-ICAM-I) levels in bladder carcinoma patients with different stages
    Ugur Coskun
    Gazi University Medical School, Department of Medical Oncology, Ankara, Turkey
    Int Immunopharmacol 6:672-7. 2006
    ..Thus, we suggest that the analysis of serum s-VCAM-I levels may provide a prognostic test for T stage and bladder cancer progression during and/or following therapy...
  3. ncbi request reprint F-18 FDG uptake due to acinetobacter infection causing misinterpretation of treatment response in a lymphoma patient
    Ramazan Yildiz
    Departments of Medical Oncology, Gazi Hospital, Gazi University School of Medicine, 06500 Besevler Ankara, Turkey
    Clin Nucl Med 32:471-3. 2007
  4. pmc Synchronous testicular liposarcoma and prostate adenocarcinoma: a case report
    Umut Demirci
    Department of Medical Oncology Gazi University Medical Faculty, 06500, Besevler, Ankara, Turkey
    Cases J 3:27. 2010
    ..We report coexistence of prostate cancer and testicular liposarcoma in a 69 year-old-man because while orchiectomy endications are decreasing day by day, these second malignancies should not be missed...
  5. ncbi request reprint UFT plus oral folinic acid with alternating oral and intravenous vinorelbine in patients with metastatic breast cancer previously treated with anthracyclines and taxanes
    Ugur Coskun
    Department of Medical Oncology, Gazi University Medical School, Ankara, Turkey
    Onkologie 32:562-6. 2009
    ..We retrospectively evaluated the activity and toxicity of uracil/tegafur (UFT) plus oral folinic acid in combination with vinorelbine (alternating intravenous (IV) on day 1 and oral on day 8) in patients with metastatic breast cancer...
  6. ncbi request reprint Significance of serum vascular endothelial growth factor, insulin-like growth factor-I levels and nitric oxide activity in breast cancer patients
    Ugur Coskun
    Department of Medical Oncology, Gazi University Medical School, Turkey
    Breast 12:104-10. 2003
    ..001). NO may involve an angiogenic process that is stimulated by VEGF in breast carcinoma. Larger studies are required to clarify these suggestions...
  7. ncbi request reprint Gemcitabine combined with uracil-tegafur in patients with advanced pancreatic cancer
    Ugur Coskun
    Department of Medical Oncology, Gazi University Medical School, Besevler, Ankara 06500, Turkey
    J Natl Med Assoc 101:761-4. 2009
    ..Most common toxicities were of hematologic and gastrointestinal nature. In conclusion, this regimen was well tolerated and seemed to have a moderate activity in the palliative treatment of advanced pancreatic carcinoma...
  8. ncbi request reprint Serum hepatocyte growth factor and interleukin-6 levels can distinguish patients with primary or metastatic liver tumors from those with benign liver lesions
    U Coskun
    Department of Medical Oncology, Gazi University Medical School, Ankara, Turkey
    Neoplasma 51:209-13. 2004
    ..Measurements of these markers in serum may be used to distinguish patients with primer liver tumors or breast cancer patients with liver metastasis from those with benign liver lesions or non-metastatic patients...
  9. pmc Effect of tamoxifen on serum IL-18, vascular endothelial growth factor and nitric oxide activities in breast carcinoma patients
    U Coskun
    Department of Medical Oncology, Gazi University Medical School, Ankara, Turkey
    Clin Exp Immunol 137:546-51. 2004
    ..The negative effect of tamoxifen therapy on IL-18, which is known to have a potent antitumour activity, may be related to the decreased tumour growth by induction of NO and reduction of VEGF activity as a feedback mechanism...
  10. doi request reprint Peritumoral lymphatic microvessel density associated with tumor progression and poor prognosis in gastric carcinoma
    Ugur Coskun
    Department of Medical Oncology, Gazi University Medical School, Ankara, Turkey
    J Surg Res 164:110-5. 2010
    ..The aim of the present study was to evaluate the clinical significance of lymphangiogenesis and its regulation in gastric carcinomas...
  11. doi request reprint Single agent gemcitabine in the second-line treatment of advanced non-small cell lung cancer after treatment with taxane + platinum regimens
    Ugur Coskun
    Department of Medical Oncology, Gazi University Medical School, Ankara, Turkey
    Med Oncol 25:133-6. 2008
    ..Grade 3/4 nausea and vomiting and mucositis were reported in one (4.75%) patient. In conclusion, this study shows that single agent gemcitabine is active and well tolerated as a second-line therapy for advanced NSCLC...
  12. ncbi request reprint Xelox (capecitabine plus oxaliplatin) as neoadjuvant chemotherapy of unresectable liver metastases in colorectal cancer patients
    U Coskun
    Gazi University Medical School, Department of Oncology, Ankara, Turkey
    Neoplasma 55:65-70. 2008
    ..Further studies of XELOX in combination with bevacizumab and/ or cetuximab are warranted in this setting...
  13. ncbi request reprint Effect of different neoadjuvant chemotherapy regimens on locally advanced breast cancer
    U Coskun
    Department of Medical Oncology, Gazi University Medical School, 06560 Ankara, Turkey
    Neoplasma 50:210-6. 2003
    ..Long-term effects of these regimens should be investigated in further randomized trials...
  14. ncbi request reprint Locally advanced breast carcinoma treated with neoadjuvant chemotherapy: are the changes in serum levels of YKL-40, MMP-2 and MMP-9 correlated with tumor response?
    U Coskun
    Gazi University Medical School, Department of Medical Oncology, Ankara, Turkey
    Neoplasma 54:348-52. 2007
    ..Serum measurement of YKL-40 can be a helpful tool to predict pathological tumor response in breast cancer patients with neoadjuvant chemotherapy but not MMP-2 and MMP-9...
  15. ncbi request reprint Effect of cisplatin on skin metastasis in breast cancer patients
    U Coskun
    Department of Medical Oncology, Gazi University Medical School, Ankara, Turkey
    Onkologie 24:576-9. 2001
    ..Metastatic breast cancer is a common clinical entity, and its treatment is still a major clinical problem in modern oncology. Both cisplatin (CDDP) and 5-fluorouracil (5-FU) are effective agents...
  16. ncbi request reprint Tamoxifen therapy and hepatic steatosis
    U Coskun
    Gazi University Medical School, Department of Medical Oncology, Ankara, Turkey
    Neoplasma 49:61-4. 2002
    ..Whether hepatic steatosis is dependent on lipid changes in tamoxifen use should be further investigated...
  17. ncbi request reprint A case of Sweet's syndrome developed after the treatment of herpes simplex infection in a metastatic breast cancer patient
    Ugur Coskun
    Gazi University Medical School, Department of Medical Oncology, Ankara, Turkey
    J Cutan Pathol 29:301-4. 2002
    ..Sweet's syndrome or acute febrile neutrophilic dermatosis is associated with several systemic diseases such as malignancies and infectious diseases...
  18. ncbi request reprint Primary mediastinal yolk sac tumor in a 66-year-old woman
    Ugur Coskun
    Department of Medical Oncology, Gazi University Medical School, Ankara, Turkey
    Med Princ Pract 11:218-20. 2002
    ..To report a rare case of nonseminomatous extragonadal germ cell tumor in a 66-year-old female with primary yolk sac tumor of the mediastinum...
  19. ncbi request reprint Primary high grade malignant lymphoma of bladder
    Ugur Coskun
    Gazi University Medical School, Department of Medical Oncology, Ankara, Turkey
    Urol Oncol 7:181-3. 2002
    ..In this report, a case with high-grade primary malignant lymphoma of bladder is reported and the clinical, pathological aspects of diseases are reviewed...
  20. ncbi request reprint Serum leptin, prolactin and vascular endothelial growth factor (VEGF) levels in patients with breast cancer
    U Coskun
    Department of Medical Oncology, Gazi University Medical School, Ankara, Turkey
    Neoplasma 50:41-6. 2003
    ..However, serum leptin and prolactin levels does not seem to be related with angiogenic activity and metastasis in breast cancer patients...
  21. doi request reprint Bevacizumab-containing chemotherapy is safe in patients with unresectable metastatic colorectal cancer and a synchronous asymptomatic primary tumor
    Bulent Cetin
    Division of Medical Oncology, Department of Internal Medicine, Gazi University Faculty of Medicine, Besevler, Ankara 06500, Turkey
    Jpn J Clin Oncol 43:28-32. 2013
    ..Concerns and controversies remain over combining cytotoxic chemotherapy with bevacizumab in this patient population...
  22. ncbi request reprint Carboplatin and oral cyclophosphamide combination after temozolomide failure in malignant gliomas
    Emel Yaman
    Department of Medical Oncology, Gazi University, Faculty of Medicine, Ankara, Turkey
    Tumori 94:674-80. 2008
    ..In the present study, we assessed retrospectively the efficacy and toxicity of the combination of carboplatin and oral cyclophosphamide in temozolomide-resistant patients...
  23. ncbi request reprint Whole body 18F-FDG PET/CT imaging in the detection of primary tumours in patients with a metastatic carcinoma of unknown origin
    Ali Osman Kaya
    Gazi University, School of Medicine, Department of Medical Oncology, Turkey
    Asian Pac J Cancer Prev 9:683-6. 2008
    ..The aim of this study was to evaluate the role of whole body 18F-FDG PET/CT imaging in the detection of primary tumors in patients with a metastatic cancer from an unknown primary site...
  24. ncbi request reprint Docetaxel combined with oral etoposide as second-line treatment for advanced gastric carcinoma after failure of platinum- and fluoropyrimidine-based regimens
    Ramazan Yildiz
    Department of Medical Oncology, Gazi University Medical School, Ankara, Turkey
    J Oncol Pharm Pract 16:173-8. 2010
    ..In the present study, we determined the efficacy and the safety of docetaxel and oral etoposide as second-line combination chemotherapy after failure of commonly used combination regimens in AGC...
  25. doi request reprint Acne rosacea associated imatinib mesylate in a gastrointestinal stromal tumor patient
    Umut Demirci
    Department of Medical Oncology, Gazi University, Ankara, Turkey
    J Oncol Pharm Pract 17:285-7. 2011
    ..AR was arisen due to the discontinuation of IM. To the best of our knowledge, this kind of cutaneous side-effect with IM has not been documented previously...
  26. doi request reprint The efficacy and toxicity of irinotecan with leucovorin and bolus and continuous infusional 5-fluorouracil (FOLFIRI) as salvage therapy for patients with advanced gastric cancer previously treated with platinum and taxane-based chemotherapy regimens
    Ali Osman Kaya
    Bakırkoy Dr Sadl Konuk Training and Research Hospital, Department of Medical Oncology, Istanbul, Turkey
    J Chemother 24:217-20. 2012
    ..2). The most common observed grade 3/4 toxicities were neutropenia (23.7%), diarrhea (6.2%), and stomatitis (5.2%). FOLFIRI regimen is safe and effective in the second-line treatment of AGC patients pre-treated with cisplatin and taxanes...
  27. doi request reprint Concomitant chemoradiotherapy with cisplatin and docetaxel followed by surgery and consolidation chemotherapy in patients with unresectable locally advanced non-small cell lung cancer
    Ali Osman Kaya
    Department of Medical Oncology, Gazi University Faculty of Medicine, Ankara, Turkey
    Med Oncol 27:152-7. 2010
    ..To evaluate preoperative concomitant chemoradiation using cisplatin plus docetaxel followed by consolidation chemotherapy in patients with unresectable locally advanced non-small cell lung cancer (NSCLC)...
  28. doi request reprint Survivin expression and its potential clinical significance in gastrointestinal stromal sarcoma
    Meltem Baykara
    Gazi University Medical Faculty, Department of Medical Oncology, Ankara, Turkey
    Int Immunopharmacol 11:2227-31. 2011
    ..We believe that additional studies are warranted to determine the clinical significance of survivin expression as a prognostic or predictive marker in patients with GIST...
  29. doi request reprint Efficacy and toxicity of Trastuzumab and Paclitaxel plus Capecitabine in the first-line treatment of HER2-positive metastatic breast cancer
    Onder Tonyali
    Division of Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Gazi University, 06500, Besevler, Ankara, Turkey
    J Cancer Res Clin Oncol 139:981-6. 2013
    ..This retrospective study evaluated the efficacy and toxicity of trastuzumab and paclitaxel plus capecitabine in the first-line therapy for patients with HER2-positive MBC...
  30. ncbi request reprint Prognostic factors for overall survival in patients with metastatic colorectal carcinoma treated with vascular endothelial growth factor-targeting agents
    Bulent Cetin
    Department of Internal Medicine, Gazi University Faculty of Medicine, Ankara, Turkey
    Asian Pac J Cancer Prev 13:1059-63. 2012
    ..The present study was conducted to establish a prognostic model for patients using an oxaliplatin-based or irinotecan-based chemotherapy plus bevacizumab in metastatic colorectal cancer...
  31. ncbi request reprint Efficacy and safety of concomitant chemoradiotherapy with cisplatin and docetaxel in patients with locally advanced squamous cell head and neck cancers
    Meltem Baykara
    Department of Medical Oncology, Sakarya University Training and Research Hospital, Sakarya, Turkey
    Asian Pac J Cancer Prev 14:2557-61. 2013
    ..We therefore retrospectively evaluated the efficacy and tolerability of a weekly cisplatin+docetaxel combination with CRT in locally advanced SCHNC...
  32. ncbi request reprint Efficacy and toxicity of gemcitabine plus docetaxel combination as a second line therapy for patients with advanced stage soft tissue sarcoma
    Ali Osman Kaya
    Department of Medical Oncology, Bakirkoy Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey
    Asian Pac J Cancer Prev 13:463-7. 2012
    ..To assess the safety and efficacy of a gemcitabine plus docetaxel regimen as a second line therapy for patients with advanced soft tissue sarcoma (STS) resistant to doxorubicin and ifosfamide-based therapy...
  33. ncbi request reprint Radiation induced early necrosis in patients with malignant gliomas receiving temozolomide
    Emel Yaman
    Department of Medical Oncology, Mersin State Hospital, Mersin, Turkey
    Clin Neurol Neurosurg 112:662-7. 2010
    ..The aim of this study was to evaluate the patients receiving temozolomide showing early clinical or radiological progression and impact of early necrosis on follow-up...
  34. ncbi request reprint The results of three different treatment modalities in patients with locally advanced nasopharyngeal carcinoma
    Banu Ozturk
    Gazi University Medical School, Department of Medical Oncology, Gazi Hospital, Ankara 06500, Turkey
    Med Oncol 25:269-73. 2008
    ..No difference was observed in median OS and PFS among three groups. In our study, the efficacy and toxicity of neoadjuvant and/or adjuvant chemotherapy with CCRT and CCRT alone were found similar...
  35. ncbi request reprint Prognostic value of serum IL-18 and nitric oxide activity in breast cancer patients at operable stage
    Nazan Gunel
    Department of Medical Oncology, Gazi University Medical School, Ankara, Turkey
    Am J Clin Oncol 26:416-21. 2003
    ..05). In conclusion, serum IL-18 level may be a useful marker to predict prognosis of patients with breast cancer in complete remission after surgery. Long-term follow-up is required to clarify this hypothesis...
  36. doi request reprint Coexistence Hodgkin's lymphoma and colonic adenocarcinoma: a case report
    Umut Demirci
    Department of Medical Oncology, Gazi University Medical Faculty, Ankara, Turkey
    Med Oncol 27:62-4. 2010
    ..The disease was confirmed with the removal of right posterior cervical lymph node. Coexistence of colonic carcinoma and lymphoma in the same patient is an uncommon event...
  37. doi request reprint Bevacizumab plus irinotecan-based therapy in metastatic colorectal cancer patients previously treated with oxaliplatin-based regimens
    Ramazan Yildiz
    Department of Medical Oncology, Gazi University Faculty of Medicine, Ankara, Turkey
    Cancer Invest 28:33-7. 2010
    ..Efficacy and toxicity of bevacizumab plus irinotecan-based regimens were assessed in the second-line treatment of MCRC patients...
  38. doi request reprint Gemcitabine plus capecitabine combination in metastatic breast cancer patients previously treated with anthracyclines and taxanes
    Mustafa Benekli
    Department of Medical Oncology, Erciyes University Faculty of Medicine, Kayseri, Turkey
    Oncology 72:308-13. 2007
    ..Effective and well-tolerated regimens are required. Gemcitabine plus capecitabine combination was assessed in MBC patients pretreated with anthracyclines and taxanes...
  39. ncbi request reprint Capecitabine plus oxaliplatin (xelox) in the treatment of chemotherapy-naive patients with metastatic colorectal cancer
    Emel Yaman
    Department of Medical Oncology, Gazi University Medical School, Besevler, Ankara, Turkey
    Med Oncol 24:431-5. 2007
    ..We evaluated our experience at two centers with capecitabine and oxaliplatin combination (XELOX) in previously untreated patients with MCRC...
  40. ncbi request reprint Interdigitating dendritic cell tumor with breast and cervical lymph-node involvement: a case report and review of the literature
    Omer Uluoglu
    Department of Pathology, Gazi University Medical School, Ankara, Turkey
    Virchows Arch 446:546-54. 2005
    ..IDCT has the potential for an aggressive clinical course. However, 32 months after the initial diagnosis, the patient is still alive and being followed with a stable tumor burden...
  41. doi request reprint Bevacizumab every 4 weeks is as effective as every 2 weeks in combination with biweekly FOLFIRI in metastatic colorectal cancer
    Ramazan Yildiz
    Departments of Medical Oncology, Gazi University Faculty of Medicine, Besevler, 06500 Ankara, Turkey
    J Cancer Res Clin Oncol 138:1845-52. 2012
    ....
  42. ncbi request reprint Synchronous bilateral breast cancer in an aged male patient
    Emel Yaman
    Department of Medical Oncology, Mersin State Hospital, Mersin, Turkey
    Onkologie 33:255-8. 2010
    ..Male breast cancer is an uncommon disease. Moreover, synchronous bilateral breast cancer is extremely rare in men. The management is still undefined, although it shows similarities to breast cancers in women...
  43. ncbi request reprint Serum granulocyte macrophage-colony stimulating factor: a tumor marker in colorectal carcinoma?
    Umut Demirci
    Department of Medical Oncology, Faculty of Medicine, Gazi University, Ankara, Turkey
    Asian Pac J Cancer Prev 10:1021-4. 2009
    ..The aim of the present study was to determine the effect of GM-CSF and carcinoembryogenic antigen levels in predicting survival...
  44. ncbi request reprint The role of positron emission tomography with 18F-fluorodeoxyglucose in nodal staging of clinical and radiological N₀ head and neck cancers
    Bulent Cetin
    Division of Medical Oncology, Department of Internal Medicine, Gazi University Faculty of Medicine, Besevler, Ankara 06500, Turkey
    Eur Arch Otorhinolaryngol 270:2307-13. 2013
    ..PET/CT proved to be accurate in 27 (75%) patients and inaccurate in 9 (25%) patients. PET/CT was a valuable tool to assess nodal stage of head and neck cancers, and should be considered before surgical treatment...
  45. ncbi request reprint Gemcitabine plus paclitaxel as second-line chemotherapy in patients with advanced non-small cell lung cancer
    Meltem Baykara
    Department of Medical Oncology, Sakarya University Training and Research Hospital, Sakarya, Turkey
    Asian Pac J Cancer Prev 13:5119-24. 2012
    ....
  46. doi request reprint Lapatinib plus capecitabine for brain metastases in patients with human epidermal growth factor receptor 2-positive advanced breast cancer: a review of the Anatolian Society of Medical Oncology (ASMO) experience
    Bulent Cetin
    Department of Medical Oncology, Gazi University Faculty of Medicine, Ankara, Turkey
    Onkologie 35:740-5. 2012
    ..We investigated the clinical outcome of patients with brain metastases (BMs) from human epidermal growth factor receptor 2-positive (HER2+) metastatic breast cancer (MBC) treated with lapatinib and capecitabine (LC)...
  47. doi request reprint Paclitaxel plus doxorubicin chemotherapy as second-line therapy in patients with advanced urothelial carcinoma pretreated with platinum plus gemcitabine chemotherapy
    Ali O Kaya
    Department of Medical Oncology, Bakirkoy Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey
    Onkologie 35:576-80. 2012
    ..We retrospectively evaluated the efficacy and toxicity of paclitaxel plus doxorubicin as a second-line treatment in patients with urothelial carcinoma, who had not responded to a prior platinum plus gemcitabine combination...
  48. ncbi request reprint Cisplatin plus docetaxel combination in the first-line treatment of metastatic non-small cell lung cancer
    Ali Osman Kaya
    Gazi University Faculty of Medicine, Department of Medical Oncology, Ankara, Turkey
    Tumori 96:400-4. 2010
    ..To evaluate activity and toxicity of cisplatin plus docetaxel combination in the first-line treatment of chemotherapy-naive patients with metastatic non-small cell lung cancer...
  49. ncbi request reprint Serum leptin levels are associated with tamoxifen-induced hepatic steatosis
    Nazan Gunel
    Department of Medical Oncology, Gazi University Medical School, Ankara, Turkey
    Curr Med Res Opin 19:47-50. 2003
    ..In this study, we compared serum leptin levels in tamoxifen-treated patients with and without hepatic steatosis...
  50. doi request reprint Cyclooxygenase-2 expression and its association with angiogenesis, Helicobacter pylori, and clinicopathologic characteristics of gastric carcinoma
    Deniz Yamac
    Department of Medical Oncology, Gazi University Medical School, Ankara, Turkey
    Pathol Res Pract 204:527-36. 2008
    ..Other factors which may be associated with COX-2 in gastric cancer, including angiogenesis and H.-pylori infection, should be investigated in further studies...
  51. ncbi request reprint Prognostic factors for recurrence-free survival in patients with HER2-positive early-stage breast cancer treated with adjuvant trastuzumab
    Onder Tonyali
    Division of Medical Oncology, Department of Internal Medicine, Gazi University Faculty of Medicine, Ankara, Turkey
    Onkologie 36:554-8. 2013
    ..The objective of this study was to identify prognostic factors affecting the recurrence-free survival (RFS) in patients who received a 52-week trastuzumab therapy for HER2-positive early stage breast cancer (EBC)...
  52. doi request reprint Is the pretreatment neutrophil to lymphocyte ratio an important prognostic parameter in patients with metastatic renal cell carcinoma?
    Bulent Cetin
    Department of Internal Medicine, Division of Medical Oncology, Gazi University Faculty of Medicine, Ankara, Turkey
    Clin Genitourin Cancer 11:141-8. 2013
    ..The NLR, an index of systemic inflammation, is associated with outcome in several cancer types. To study the association of pretreatment NLR with PFS and overall survival (OS) of patients treated with VEGF-targeted therapy...
  53. ncbi request reprint Clinicopathological features in bilateral breast cancer
    Meltem Baykara
    Department of Medical Oncology, Gazi University Medical Faculty, Ankara, Turkey
    Asian Pac J Cancer Prev 13:4571-5. 2012
    ....
  54. ncbi request reprint The nodal standard uptake value (SUV) as a prognostic factor in head and neck squamous cell cancer
    Umut Demirci
    Department of Medical Oncology, Ataturk Education and Research Hospital, Turkey
    Asian Pac J Cancer Prev 12:1817-20. 2011
    ..Abnormal FDG uptakes were analyzed using maximum standardized uptake values (SUVm). The disease-free survival (DFS) and overall survival (OS) were evaluated with several prognostic factors such as pre-treatment SUVm and %change in SUVm...
  55. doi request reprint Hepatotoxicity associated with lapatinib in an experimental rat model
    Umut Demirci
    Ataturk Education and Research Hospital, Department of Medical Oncology, Ankara, Turkey
    Eur J Cancer 48:279-85. 2012
    ..The current study is the first to evaluate the biochemical and histopathological features of hepatic toxicity of lapatinib...
  56. ncbi request reprint Coexistence of gastrointestinal stromal tumor (GIST) of the rectum and adenocarcinoma of the prostate in a patient with familial GIST
    Emel Yaman
    Department of Medical Oncology, Gazi University Faculty of Medicine, Ankara, Turkey
    Onkologie 31:697-9. 2008
    ..The rectum is a rare location for GIST. Prostate adenocarcinoma is the most common malignancy in geriatric men. Rarely, rectal GIST mimics prostate pathologies...
  57. ncbi request reprint Increased serum granulocyte colony stimulating factor in Turkish hepatocellular carcinoma patients
    Ali Osman Kaya
    Department of Medical Oncology, Faculty of Medicine, Gazi University, Ankara, Turkey
    Asian Pac J Cancer Prev 10:403-6. 2009
    ..To evaluate the serum levels of G-CSF in patients with hepatocellular carcinoma and to compare with values in healthy individuals...
  58. ncbi request reprint The effect of bevacizumab on serum soluble FAS/FASL and TRAIL and its receptors (DR4 and DR5) in metastatic colorectal cancer
    Ramazan Yildiz
    Department of Medical Oncology, Gazi University Faculty of Medicine, Besevler, Ankara 06500, Turkey
    J Cancer Res Clin Oncol 136:1471-6. 2010
    ....
  59. doi request reprint Opportunistic cytomegalovirus infection in a patient receiving temozolomide for treatment of malignant glioma
    Emel Yaman
    Department of Medical Oncology, Gazi University Faculty of Medicine, Ankara 06500, Turkey
    J Clin Neurosci 16:591-2. 2009
    ..To our knowledge, although there have been reported cases of Pneumocystis carinii infection associated with temozolomide therapy, there has only been one other case of CMV infection. We also review this report...
  60. ncbi request reprint Prognostic importance of COX-2 expression in patients with colorectal cancer
    Deniz Yamac
    Department of Medical Oncology, Gazi University Medical School, Ankara, Turkey
    Pathol Res Pract 201:497-502. 2005
    ..In the multivariate analysis, COX-2 expression was not found as an independent prognostic factor. We demonstrated that COX-2 expression was not correlated with clinicopathological characteristics of colon carcinoma and disease outcome...
  61. ncbi request reprint Clinical importance of serum interleukin-18 and nitric oxide activities in breast carcinoma patients
    Nazan Gunel
    Department of Medical Oncology, Gazi University Medical School, Ankara, Turkey
    Cancer 95:663-7. 2002
    ..Nitric oxide (NO) is a pleiotropic molecule that participates in the multistep processing of carcinogenesis...
  62. doi request reprint Gemcitabine-induced acute coronary syndrome: a case report
    Banu Ozturk
    Department of Medical Oncology, Gazi University Medical School, Ankara, Turkey
    Med Princ Pract 18:76-80. 2009
    ..To report a case of metastatic leiomyosarcoma, in which a patient developed chest pain accompanied by acute left bundle-branch block (LBBB) after gemcitabine infusion...
  63. ncbi request reprint Serum YKL-40 levels as a prognostic factor in patients with locally advanced breast cancer
    Deniz Yamac
    Department of Medical Oncology, Gazi University Medical School, Ankara, Turkey
    Adv Ther 25:801-9. 2008
    ..In the present study we evaluated the prognostic role of serum YKL-40 levels in patients with locally advanced breast cancer...
  64. ncbi request reprint Prognostic importance of tumor angiogenesis in breast carcinoma with adjuvant chemotherapy
    Nazan Gunel
    Gazi University Medical School, Department of Medical Oncology, Turkey
    Pathol Res Pract 198:7-12. 2002
    ..Additional studies are necessary to demonstrate the clinical importance of angiogenesis...
  65. doi request reprint Acute erythema and edematous skin reaction and ectropion following docetaxel in a patient with non-small cell lung cancer
    Ali Osman Kaya
    Department of Medical Oncology, Gazi University Faculty of Medicine, Ankara, Turkey
    Cutan Ocul Toxicol 27:327-31. 2008
    ..Docetaxel-associated skin reactions that are so extensive and severe as to lead to eye madarosis and ectropion are reported rarely in the literature...
  66. ncbi request reprint Efficacy of sunitinib in Turkish patients with gastrointestinal stromal tumors; retrospective multicenter experience
    Umut Kefeli
    Department of Medical Oncology, Dr Lutfi Kirdar Kartal Education and Research Hospital, Istanbul, Turkey
    Hepatogastroenterology 60:647-52. 2013
    ..Sunitinib is a multi-targeted thyrosine kinase receptor inhibitor used in patients with advanced gastrointestinal stromal tumours (GISTs). We evaluated the efficacy and tolerability of sunitinib therapy in Turkish patients with GISTs...
  67. doi request reprint Assessment of right ventricular functions during cancer chemotherapy
    Asli Tanindi
    Department of Cardiology, Gazi University Faculty of Medicine, Besevler, Ankara, Turkey
    Eur J Echocardiogr 12:834-40. 2011
    ..We aimed to investigate the early effects of chemotherapy on right heart, if any, in addition to the association between N-terminal pro-brain natriuretic peptide (NT-proBNP) and right heart echocardiographic indices...
  68. ncbi request reprint Temozolomide in newly diagnosed malignant gliomas: administered concomitantly with radiotherapy, and thereafter as consolidation treatment
    Emel Yaman
    Department of Medical Oncology, Gazi University Faculty of Medicine, Ankara, Turkey
    Onkologie 31:309-13. 2008
    ..We evaluated retrospectively the efficacy and the toxicity of temozolomide which was administered concomitantly with radiotherapy, and thereafter as consolidation treatment...
  69. doi request reprint Bevacizumab plus irinotecan in recurrent or progressive malign glioma: a multicenter study of the Anatolian Society of Medical Oncology (ASMO)
    Umut Demirci
    Department of Medical Oncology, Ataturk Training and Research Hospital, Bilkent, Ankara 0906800, Turkey
    J Cancer Res Clin Oncol 139:829-35. 2013
    ..We evaluated our multicenter retrospective experience for patients with recurrent MG administering bevacizumab and irinotecan in combination therapy...
  70. ncbi request reprint Sister Mary Joseph's nodule as a rare sign of lymphoma
    Bulent Cetin
    Division of Medical Oncology, Department of Internal Medicine, Gazi University Faculty of Medicine, Besevler, Ankara, 06500, Turkey
    Int J Hematol 94:209-12. 2011
    ..We should keep in mind that not all periumbilical tumoral deposits are the same...
  71. doi request reprint Histiocytic sarcoma: PET-CT evaluation of a rare entity
    Emel Yaman
    Department of Medical Oncology, Gazi University Faculty of Medicine, Besevler, Ankara, 06500, Turkey
    Ann Nucl Med 22:715-7. 2008
    ..The pertinent literature is reviewed...
  72. doi request reprint Synchronize primary breast osteosarcoma and contralateral benign cystosarcoma phylloides: radiologic and pathologic imaging
    Aytug Uner
    Department of Medical Oncology, Gazi University Medical School, Ankara, Turkey
    Breast J 14:109-10. 2008
  73. ncbi request reprint Efficacy and toxicity of gemcitabine and pegylated liposomal Doxorubicin in recurrent platinum-resistant/refractory epithelial ovarian cancer
    Aziz Karaoglu
    Department of Medical Oncology, Firat University, Elazig, Turkey
    Asian Pac J Cancer Prev 10:63-6. 2009
    ..In this study, we evaluated the efficacy and tolerability of the combination of gemcitabine and pegylated liposomal doxorubicin (PLD) in patients with platinum resistant/refractory ovarian cancer...
  74. doi request reprint Elevated serum levels of M30 and M65 in patients with locally advanced head and neck tumors
    Banu Ozturk
    Department of Medical Oncology, Gazi University Medical School, Ankara, Turkey
    Int Immunopharmacol 9:645-8. 2009
    ..In the present study, we measured serum M30 and M65 levels in the patients with locally advanced head and neck tumors, and compared with healthy controls...
  75. ncbi request reprint The prognostic value of p53 and c-erbB-2 expression, proliferative activity and angiogenesis in node-negative breast carcinoma
    Ozlem Erdem
    Department of Pathology, Faculty of Medicine, Gazi University, Ankara, Turkey
    Tumori 91:46-52. 2005
    ....
  76. ncbi request reprint Imatinib mesylate-induced acute liver failure in a patient with gastrointestinal stromal tumors
    Onder Tonyali
    Faculty of Medicine, Department of Medical Oncology, Gazi University, 06500, Besevler Ankara, Turkey
    Med Oncol 27:768-73. 2010
    ..In cases of imatinib-induced acute hepatitis, the administration of prednisolone may be useful in the resolution of the acute episode and allow the reintroduction of a drug without risking recurrence of hepatitis...
  77. ncbi request reprint Solitary iris metastasis from breast cancer with dramatic course: case report
    Banu Ozturk
    Department of Medical Oncology, Gazi University Medical Faculty, Gazi Hospital, Besevler, Ankara, Turkey
    Med Oncol 24:463-5. 2007
    ..The eye metastases of breast cancer are a part of systemic illness and must be treated by systemic chemotherapy...
  78. ncbi request reprint Risk factors of nasopharyngeal carcinoma in Turkey-an epidemiological survey of the Anatolian Society of Medical Oncology
    Fatma Paksoy Türköz
    Department of Medical Oncology, Ankara Oncology Teaching and Research Hospital, Ankara, Turkey
    Asian Pac J Cancer Prev 12:3017-21. 2011
    ..This is the first epidemiologic study aimed to evaluate the risk factors of nasopharyngeal carcinoma in the Turkish population...
  79. doi request reprint Isolated mucinous adrenal metastasis in a breast cancer patient
    Umut Demirci
    Faculty of Medicine, Department of Medical Oncology, Gazi University, Ankara, Turkey
    J Oncol Pharm Pract 17:444-7. 2011
    ..This case is unique due to the unexpected metastasis of pure mucinous carcinoma developed after 4 years of hormone therapy...
  80. ncbi request reprint Non-gestational uterine choriocarcinoma in a postmenopausal woman
    Ramazan Yildiz
    Department of Medical Oncology, Gazi University Medical School, Ankara, Turkey
    Onkologie 32:417-9. 2009
    ..Gestational trophoblastic disease occurs rarely in postmenopausal women...
  81. doi request reprint Ischemic colitis after capecitabine plus cisplatin treatment in advanced gastric cancer
    Bulent Cetin
    Division of Medical Oncology, Department of Internal Medicine, Gazi University Medical School, Ankara 06500, Turkey
    J Thromb Thrombolysis 31:503-6. 2011
    ..Once Clostridium difficile infection has been excluded, a diagnosis of ischemic colitis should be considered, especially in patients with cancer who have normal white blood cell counts...
  82. doi request reprint Parathyroid adenoma and chondrosarcoma after treatment of pediatric Hodgkin disease
    Ebru Yilmaz Keskin
    Department of Pediatric Hematology, Gazi University, Medical School, Ankara, Turkey
    J Pediatr Hematol Oncol 32:e294-6. 2010
    ..Consecutive occurrence of PTA and CS after treatment of pediatric HD, to the best of our knowledge, has not been reported earlier...
  83. ncbi request reprint Granulocyte colony stimulating factor (G-CSF) and macrophage colony stimulating factor (M-CSF) as potential tumor markers in non small cell lung cancer diagnosis
    Burak Bahar
    Department of Biochemistry, Faculty of Medicine, Gazi University, Ankara, Turkey
    Asian Pac J Cancer Prev 11:709-12. 2010
    ..There are different results in the literature about cytokine levels in NSCLC patients but the main conclusion, with which we concur, is that ongoing studies will provide consistent results of value to patients...
  84. doi request reprint Acute cholecystitis in a patient with metastatic renal cell carcinoma treated with everolimus
    Bulent Cetin
    Department of Medical Oncology, School of Medicine, Gazi University, Ankara, Turkey
    J Oncol Pharm Pract 17:274-8. 2011
    ..We report herein the first case of a metastatic renal cell carcinoma developed everolimus-associated cholecystitis that was completely reversed after drug withdrawal...
  85. doi request reprint Primary adult soft tissue sarcomas: analysis of 294 patients
    Necati Alkis
    Department of Medical Oncology, Ankara Oncology Hospital, Ankara, Turkey
    Med Oncol 28:391-6. 2011
    ..The 1-year overall survival for all patients was 73.4%, 3-year overall survival was 51.8%, and 5-year overall survival was 45.1%...
  86. ncbi request reprint Clinical significance of serum MMP-2 and MMP-7 in patients with ovarian cancer
    Ayla Acar
    Department of Obstetrics and Gynecology, Gazi University Medical School, Ankara, Turkey
    Med Oncol 25:279-83. 2008
    ..05). As a conclusion, MMP-7 can be a useful serum marker to show disease activity in malignant ovarian tumors...
  87. ncbi request reprint Polymyositis and hepatitis concurrent with breast cancer
    Deniz Yamac
    Department of Medical Oncology, Gazi University Medical School, Ankara, Turkey
    Med Princ Pract 13:171-5. 2004
    ..To present a rare case of breast cancer associated with both inflammatory muscle disease and liver disease as a paraneoplastic syndrome...
  88. ncbi request reprint Disseminated extranodal NK/T-cell lymphoma, nasal type, with multiple subcutaneous nodules: utility of 18F-FDG PET in staging
    Veli Berk
    Department of Medical Oncology, Gazi University Faculty of Medicine, Ankara, Turkey
    Clin Nucl Med 33:365-6. 2008
    ..There is limited literature data on the use of the PET scan in the diagnosis and staging of extranodal nasal NK/T-cell lymphomas. Our case highlights the important role of F-18 FDG PET in the staging of these patients...
  89. ncbi request reprint Serum interleukin-18 and nitric oxide activity in bladder carcinoma
    Neslihan Bukan
    Gazi University Medical School, Department of Biochemistry, Ankara, Turkey
    Eur Cytokine Netw 14:163-7. 2003
    ..Both interleukin-18 and nitric oxide are multifunctional molecules that are involved in the different steps of carcinogenesis...
  90. ncbi request reprint Digital ischemic changes after gemcitabine therapy in a patient with metastatic non-small-cell lung cancer
    Ramazan Yildiz
    Ann Pharmacother 41:901-2. 2007
  91. ncbi request reprint Serum big endothelin-1 levels in female patients with breast cancer
    Yesim Yildirim
    Baskent University Department of Medical Oncology, Turkey
    Int Immunopharmacol 8:1119-23. 2008
    ..Serum big ET- 1 levels can be an indicator of the breast cancer. Further studies are needed to demonstrate the prognostic importance of serum big ET-1 in patients with breast cancer...
  92. pmc The effects of atorvastatin therapy on endothelial function in patients with coronary artery disease
    Ahmet Yildiz
    Department of Cardiology, Gazi Hospital, Izmir, Turkey
    Cardiovasc Ultrasound 5:51. 2007
    ..These functions of statins have been briefly described as pleiotropic effects. The aim of our study was to evaluate the effect of atorvastatin therapy on endothelial functions in patients with CAD...
  93. ncbi request reprint Inhibitory effect of 5-fluorouracil on cytochrome P450 2C9 activity in cancer patients
    Arzu Gunes
    Department of Pharmacology, Gazi University, Medical Faculty, Ankara, Turkey
    Basic Clin Pharmacol Toxicol 98:197-200. 2006
    ..This inhibition was more pronounced when the total administered dose increased. This finding may help explain the mechanism of interaction between 5-fluorouracil and CYP2C9 substrates...