W A Corrigall

Summary

Publications

  1. ncbi request reprint Nicotine self-administration in animals as a dependence model
    W A Corrigall
    Biobehavioural Research Department, University of Toronto, Canada
    Nicotine Tob Res 1:11-20. 1999
  2. ncbi request reprint Manipulations of mu-opioid and nicotinic cholinergic receptors in the pontine tegmental region alter cocaine self-administration in rats
    W A Corrigall
    Biobehavioural Research Department, Centre for Addiction and Mental Health, ARF Division, 33 Russell Street, Toronto, Ontario, Canada, M5S 2S1
    Psychopharmacology (Berl) 145:412-7. 1999
  3. ncbi request reprint Response of nicotine self-administration in the rat to manipulations of mu-opioid and gamma-aminobutyric acid receptors in the ventral tegmental area
    W A Corrigall
    Smoking and Nicotine Dependence Research, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Psychopharmacology (Berl) 149:107-14. 2000
  4. ncbi request reprint Local perfusion of nicotine differentially modulates somatodendritic dopamine release in the rat ventral tegmental area after nicotine preexposure
    S Rahman
    Smoking and Nicotine Dependence Research, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario M5S 2S1, Canada
    Neurochem Res 29:1687-93. 2004
  5. ncbi request reprint GABA mechanisms in the pedunculopontine tegmental nucleus influence particular aspects of nicotine self-administration selectively in the rat
    W A Corrigall
    Smoking and Nicotine Dependence Research, Centre for Addiction and Mental Health, 33 Russell Street, Toronto, Ontario, Canada M5S 2S1
    Psychopharmacology (Berl) 158:190-7. 2001
  6. ncbi request reprint Neuroadaptive changes in the mesoaccumbens dopamine system after chronic nicotine self-administration: a microdialysis study
    S Rahman
    Smoking and Nicotine Dependence Research, Neuroscience Department, Centre for Addiction and Mental Health, University of Toronto, 33 Russell Street, Toronto, Ontario, M5S 2S1 Canada
    Neuroscience 129:415-24. 2004
  7. ncbi request reprint Involvement of nicotinic receptors in alcohol self-administration
    A D Le
    Centre for Addiction and Mental Health, University of Toronto, Ontario Canada
    Alcohol Clin Exp Res 24:155-63. 2000
  8. ncbi request reprint Effects of abstinence and smoking on information processing in adolescent smokers
    M Zack
    Neuroscience Department, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Psychopharmacology (Berl) 153:249-57. 2001
  9. ncbi request reprint Nicotine-induced fos expression in the pedunculopontine mesencephalic tegmentum in the rat
    A José Lança
    Centre for Addiction and Mental Health, University of Toronto, Ontario, M5S 2S1, Toronto, Canada
    Neuropharmacology 39:2808-17. 2000
  10. ncbi request reprint Nicotine maintains robust self-administration in rats on a limited-access schedule
    W A Corrigall
    Addiction Research Foundation, Toronto, Ontario, Canada
    Psychopharmacology (Berl) 99:473-8. 1989

Detail Information

Publications13

  1. ncbi request reprint Nicotine self-administration in animals as a dependence model
    W A Corrigall
    Biobehavioural Research Department, University of Toronto, Canada
    Nicotine Tob Res 1:11-20. 1999
    ..Two examples of ongoing studies of the mechanisms of dependence are discussed: the role of cholinergic projections to midbrain dopamine cells, and the influence of opioid receptors in the vicinity of these same dopamine cells...
  2. ncbi request reprint Manipulations of mu-opioid and nicotinic cholinergic receptors in the pontine tegmental region alter cocaine self-administration in rats
    W A Corrigall
    Biobehavioural Research Department, Centre for Addiction and Mental Health, ARF Division, 33 Russell Street, Toronto, Ontario, Canada, M5S 2S1
    Psychopharmacology (Berl) 145:412-7. 1999
    ..However, little is known of the receptor systems within this nucleus which might be involved. Furthermore, some research suggests that the PPTg may also be part of the neuronal circuitry involved in established drug-taking behavior...
  3. ncbi request reprint Response of nicotine self-administration in the rat to manipulations of mu-opioid and gamma-aminobutyric acid receptors in the ventral tegmental area
    W A Corrigall
    Smoking and Nicotine Dependence Research, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Psychopharmacology (Berl) 149:107-14. 2000
    ..Other neuronal elements in the VTA are important in drug reward. In particular, mu opioid receptors in the VTA have been shown to influence cocaine reinforcement...
  4. ncbi request reprint Local perfusion of nicotine differentially modulates somatodendritic dopamine release in the rat ventral tegmental area after nicotine preexposure
    S Rahman
    Smoking and Nicotine Dependence Research, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario M5S 2S1, Canada
    Neurochem Res 29:1687-93. 2004
    ..These results suggest that local nicotine challenge potentiated the somatodendritic DA release after nicotine preexposure by stimulation of high-affinity nAChRs in the VTA...
  5. ncbi request reprint GABA mechanisms in the pedunculopontine tegmental nucleus influence particular aspects of nicotine self-administration selectively in the rat
    W A Corrigall
    Smoking and Nicotine Dependence Research, Centre for Addiction and Mental Health, 33 Russell Street, Toronto, Ontario, Canada M5S 2S1
    Psychopharmacology (Berl) 158:190-7. 2001
    ..However, anatomical studies of Fos expression suggest that nicotine targets primarily non-cholinergic neurons in the PPTg, especially GABAergic and glutamatergic neurons...
  6. ncbi request reprint Neuroadaptive changes in the mesoaccumbens dopamine system after chronic nicotine self-administration: a microdialysis study
    S Rahman
    Smoking and Nicotine Dependence Research, Neuroscience Department, Centre for Addiction and Mental Health, University of Toronto, 33 Russell Street, Toronto, Ontario, M5S 2S1 Canada
    Neuroscience 129:415-24. 2004
    ..Overall, these results provide clear evidence for a neuroadaptive change that alters dopamine transmission in the ACB during abstinence from chronic i.v. nicotine exposure...
  7. ncbi request reprint Involvement of nicotinic receptors in alcohol self-administration
    A D Le
    Centre for Addiction and Mental Health, University of Toronto, Ontario Canada
    Alcohol Clin Exp Res 24:155-63. 2000
    ..Nicotinic receptors also have been implicated in alcohol action. We designed the present study to examine the possible involvement of nicotinic receptors in alcohol self-administration...
  8. ncbi request reprint Effects of abstinence and smoking on information processing in adolescent smokers
    M Zack
    Neuroscience Department, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Psychopharmacology (Berl) 153:249-57. 2001
    ..Although adolescent smokers appear to display some of the hallmark features of dependence, the biological and behavioral effects of smoking in this population are poorly understood...
  9. ncbi request reprint Nicotine-induced fos expression in the pedunculopontine mesencephalic tegmentum in the rat
    A José Lança
    Centre for Addiction and Mental Health, University of Toronto, Ontario, M5S 2S1, Toronto, Canada
    Neuropharmacology 39:2808-17. 2000
    ..We postulate that activation of these non-cholinergic neurons modulates the activity of cholinergic cells in the PMT, which in turn may alter dopamine release in the mesolimbic system...
  10. ncbi request reprint Nicotine maintains robust self-administration in rats on a limited-access schedule
    W A Corrigall
    Addiction Research Foundation, Toronto, Ontario, Canada
    Psychopharmacology (Berl) 99:473-8. 1989
    ..These results demonstrate that intravenous nicotine can maintain substantial self-administration behavior in rodents...
  11. ncbi request reprint Effects of acute and chronic nicotine on somatodendritic dopamine release of the rat ventral tegmental area: in vivo microdialysis study
    S Rahman
    Smoking and Nicotine Dependence Research, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Neurosci Lett 348:61-4. 2003
    ..The enhancement of DA release to subsequent challenge nicotine may be susceptible to mild desensitization...
  12. ncbi request reprint Acute subjective and physiological responses to smoking in adolescents
    W A Corrigall
    Smoking and Nicotine Dependence Research and Clinical Neuroscience, Centre for Addiction and Mental Health, 33 Russell Street, Toronto, Ontario, Canada
    Addiction 96:1409-17. 2001
    ..To determine the topography of cigarette smoking and the subjective and physiological effects of abstinence and nicotine in adolescents who smoke on a daily versus a non-daily basis...
  13. ncbi request reprint Effect of CYP2D1 inhibition on the behavioural effects of d-amphetamine
    D M Tomkins
    Addiction Research Foundation, Toronto, Ontario, Canada
    Behav Pharmacol 8:223-35. 1997
    ..These studies indicate that AMP is responsible for the behavioural effects seen in rats and that a rat phenocopy model of the human CYP2D6 deficiency state can be produced by CYP2D1 inhibitors...